-
Prof. Shimon Levit
Full vector path integrals for light propagation in dielectrics.Resonant scattaring off photonic slabsVariational Approach to Tunneling Dynamics.Application to Hot Superfluid Fermi Systems.Application to spontaneous and induced fissionTunneling of hot bosonic systems
Homepage
-
Prof. Sima Lev
Signaling networks in cancer development and metastasisCollaboration with: Thomas Karn, Eytan Ruppin, Gordon Mills, Flavio Maina, Frank Westermann, Yosef YardenTumorigenic signaling networks in triple negative breast cancer (TNBC) subtypesCombination therapy, drug resistance, and cancer stem cellsFerroptosis and TNBC therapyReceptor Tyrosine Kinases (RTKs) (AXL, cMet, EGFR) and non-RTKs (PYK2, FAK) signaling in TNBCEpithelial-Mesenchymal Transition (EMT) & TNBC metastasis
Homepage
-
Dr. Michal Leskes
Our research is focused on correlating structure and function in energy storage and conversion materials by advanced magnetic resonance methods. We aim to understand how the composition of materials affects their functionality and how we can control their functionality through deviation from ideal stoichiometry. In particular we are interested in materials for energy storage, such as Li and Na ion batteries, and in the role interfacial chemistry plays in the functionality of electrode and electrolyte materials. We use a wide range of magnetic resonance techniques: solid state NMR, Electron Paramagnetic Resonance (EPR) and Dynamic Nuclear Polarization (DNP). Additionally we investigate the process of polarization transfer from electron spins to nuclear spins in solids DNP utilizing external and internal polarization agents. For more detailed information, please click below and see our home page.
Homepage
-
Dr. Orly Laufman
Molecular and Cell Biology of RNA virusesRNA viruses including corona, zika and dengue are a major threat to human health. We study how RNA viruses interact with their host cells and transform them into viral manufactories.Our main model is enteroviruses - common viral pathogens that cause severe medical complications in humans, with no available therapeutic treatments.We investigate how enteroviruses remodel the structure and function of host organelles to generate an environment favorable to virus replication.Another key question we tackle is how enteroviruses, that express only a small number of proteins, take control of human cells with complex protein machineries. We study the different roles of viral proteins and the mechanisms they use to hijack host machineries.We aim to piece together the complete program of enterovirus replication. This could lead to the development of new antiviral therapeutics.
Homepage
-
Prof. Tsvee Lapidot
Metabolic regulation of Blood and Bone forming Stem Cells by Daily Light and Dark Cues (NE, TNF, Melatonin and PGE2).Regulation of Human and Murine Hematopoietic Stem Cell Migration and Development by Coagulation Cascades (both aPC/EPCR/Par1 anti inflammatory signals and Thrombin/PAR1 pro-inflammatory signals).Studying Molecular Cues guiding Human and murine Hematopoietic Stem Cells Homing and Bone Marrow (BM) recognition, retention and mobilization to the circulation.Metabolic regulation of BM Neutrophils activation and recruitment by Lactatae and GPR81 Signaling.Metabolic regulation of BM Neutrophils by Daily Light and Dark Cues.Energy sharing, Chemotherapy Resistance and Stress induced Mitochondira Transfer between Blood and Bone forming Stem Cells.AML AF9 Leukemic Stem Cells Metabolic interactions with BM Stromal Cells and Chemotherapy Resistance.Dynamic regulation of the Blood Bone Marrow Endothelial Barrier and Hematopoietic Stem Cell Niches.
Homepage
