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Prof. Avigdor Scherz
Quantification of atoms, groups and molecules electronegati using metal substituted bacteriochlorophylls and application to chemical reactivity.Resolving the forces which drive membrane protein assembly.The mechenism behind generation of reactive oxygen species (ROS) by illuminating novel bacteriochlorophyll derivatives and their application in photodynamic therapy (PDT) of tumors.
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Prof. Yardena Samuels
Synthetic lethal interaction network of melanomaIdentification of melanoma hub interactomesCRISPR screens to reveal driver gene interactions and drug resistance genesDecipher the immuno-genetic interactions between melanoma and T cellsHLA peptidome analysis of metastatic melanoma lesions
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Prof. Yoram Salomon
Anti-cancer treatments :Development of novel bacteriochlorophyll-based drugs for photochemotherapy.Boron neutron capture therapy.Reactive oxygen species, their generation by bacteriochlorophyll and light, their role in signal transduction and mechanisms of cell and tumor destruction.Vascular biology and vascular destruction.
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Prof. Jacob Sagiv
Supramolecular Architecture at Interfaces (with R. Maoz)Supramolecular Surface Chemistry: Bottom-up Nanofabrication using Planned Self-Assembling Mono- and Multilayer Systems (with R. Maoz)Constructive Lithography: Contact Electrochemical Surface Patterning on Lateral Length Scales from Nanometer to Centimeter (with R. Maoz)
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Prof. Menachem Rubinstein
Role of oxidative stress in type 2 diabetesCollaboration with: Mike WalkerMetabolic diseasesCAR-T optimizationCollaboration with: Zelig EshharGene therapy in cancerRole of C/EBPbeta in multidrug resistanceCollaboration with: Chiara Riganti (Univ. Torino, Italy)Cancer ResearchAttenuation of chemotherapy side effectsCollaboration with: Gillian Dank (Koret School of Veterinary Medicine of the Hebrew University of Jerusalem)Cancer Research
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