• Picture of Prof. Michal Schwartz

    Prof. Michal Schwartz

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    The cross-talk between the immune and nervous systems – autoimmunity as a mechanism of tissue repair: Molecular, cellular, physiological and behavioral aspects.
    Immunological aspects of neuronal loss in neurodegenerative and mental disorders (Alzheimer’s, ALS, Huntingdon, Glaucoma).
    Spinal cord injury and repair
    Development of vaccination for neurodegenerative disorders.
    Neurogenesis (stem cells) and inflammation in the CNS.

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  • Picture of Prof. Zippora Shakked

    Prof. Zippora Shakked

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    Crystal structure and solution studies of DNA oligomers.
    Collaboration with:  Donald Crothers (Yale University)
    DNA regulatory elements
    DNA bending by adenine-thymine tracts
    Structural and biochemical studies of proteins involved in transcriptional regulation.
    The tumor-suppressor protein p53 and its interaction with DNA and the basal transcription machinery
    The leukemia-related RUNX1(AML1) transcription regulator

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  • Picture of Prof. Irun R. Cohen

    Prof. Irun R. Cohen

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    Autoimmune T cells and tissue maintenance in the nervous system
    Collaboration with:  M. Schwartz
    Autoimmunity to hsp60 and the development of subunit vaccines against infectious diseases.
    Regulation of immune inflammation by small carbohydrate molecules
    Collaboration with:  O. Lider
    Autoimmunity to p53 and the development of systemic lupus erythematosus
    Collaboration with:  V. Rotter
    Autoimmune diabetes: Pathogenesis and immune therapy.

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  • Picture of Prof. Michel Revel

    Prof. Michel Revel

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    Applications of IL-6 Chimera and Interferon-beta in neurology, hematopoiesis, and oncology.
    Collaboration with:  J. Chebath
    Interleukin-6 Chimera, a superactivator of the gp130 receptor system: role in nerve myelination, neuroprotection and in the development of neuro-glial cells from embryonic tissues and stem cells.
    Collaboration with:  J. Chebath
    Transdifferentiation of neural crest cell derived melanoma into myelinating Schwann cell. Genes controlling cell growth, differentiation, melanogenesis and synthesis of myelin proteins.
    Collaboration with:  J. Chebath
  • Picture of Prof. Abraham Arcavi

    Prof. Abraham Arcavi

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    Research on cognitive characteristics of non academically oriented math students.
    Collaboration with:  Dr. Ronnie Karsenty
    Design of curriculum materials as a research based activity
    Collaboration with:  Dr. Sue Magidson
    Long-term design of a new curriculum for grades 10, 11 and 12 for non-academically oriented students.
    Collaboration with:  Dr. Nurit Hadas

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  • Picture of Prof. Varda Rotter

    Prof. Varda Rotter

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    Molecular mechanisms controlling the expression of p53 in normal cells and its deregulation in cancer cells
    Involvement of p53 in cell differentiation and apoptosis: <I>in vivo</I> and in vitro models.
    Cellular proteins that specifically complex with the p53 protein.
    Cellular proteins that are induced upstream or downstream to the p53 protein following genotoxic stress.

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  • Picture of Prof. David Milstein

    Prof. David Milstein

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    Organometallic chemistry and catalysis
    Bond activation by electron-rich transition metal complexes.
    Rational design of homogeneous catalysis and synthetic methodology based on transition metal complexes.
    Impact of molecular order on catalysis and reactivity.
    Generation and stabilization of elusive (potentially biologically active) molecules

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  • Picture of Prof. Michail Tsodyks

    Prof. Michail Tsodyks

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    Information transmission through dynamic synapses.
    Collaboration with:  H. Markram
    Modeling of cortical neuronal populations: From microcircuits to large scale networks.
    Population activity in visual cortex.
    Collaboration with:  A. Grinvald, D. Sagi

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  • Picture of Prof. Matityahu Fridkin

    Prof. Matityahu Fridkin

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    Chemical-Biological and Clinical studies on novel drugs, primarily of peptidic nature,related to therapy of infectious ,inflamatory and neoplastic diseases.
    Collaboration with:  Y. Koch I. Gozes (TAU ) I. Offek (TAU ) R. Catane (TEL-HASHOMER )
    Anticancer, Antibacterial Antiinflammatory
    Novel synthetic and analytical methdologies are being developed.
    Solid-phase synthesis
    Classical solution chemistry
    Combinatorial technologies
    Studies include: drug design, pro-drugs, long-acting drugs and drug delivery.
    Collaboration with:  Y. Shechter
    Novel iron chelatores as potential drugs for neurodegenarative diseases
    Collaboration with:  M. Youdim ( Technio9n )
    small-molecules
    amino acids and peptides

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  • Picture of Prof. Elazar Zelzer

    Prof. Elazar Zelzer

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    the roles of the VEGF pathway in different steps during skeletal development.
    Studying the role of mechanical load on embryonic bone development

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