Signal transduction and protein kinase C isozymes in brain of normal and growth-retarded fetuses.

Free radicals and lipid modulators in the developing and aging brain.

Novel genes during oxidative stress in utero and role of docosahexaenoic acid.

Organic synthesis through free radical reactions.

Synthesis of Yingzhaosu A and related antimalarial drug candidates.

Stereocontrol through Sulfur-Mediated Temporary Intramolecularization of Reactions.

Rational conformal field theory and solvable lattice models.

Cancer Immunity: a) Tetrameric MHC-peptide complexes in cancer detection and as cancer vaccines, b) Fas/Fas-L in tumor immunity c) Tumor escape mechanisms.

Immunological memory in cancer.

Apoptosis of the heart muscle.

Plasticity of gene expression during differenatiation in the gonads.

Crosstalk amond signals that control apoptosis.

Carcinogenesis in endocrine glands.

Anti-cancer treatments :

Reactive oxygen species, their generation by bacteriochlorophyll and light, their role in signal transduction and mechanisms of cell and tumor destruction.

Vascular biology and vascular destruction.

Comparison of the properties of the leukemogenic ALL-1 fusion proteins with those of normal ALL-1.

Transcription profiles of primary tumors with ALL-1 rearrangements.

Functions of the human ASH1 protein.

Studies of the ALR gene.

Systemic lupus erythematosus (SLE): Mechanisms for the induction and development and approaches for disease immunomodulation.

T cell and cytokine dysregulation in autoimmune diseases.

T cell epitopes of the human acetylcholine receptor and their analogs in myasthenia gravis.

Autoimmunity in aging: The SLE experimental model.

Modeling ligand-protein interactions.

Consensus structures for ATP binding sites.

Computer tools for analyzing molecular structures.

Tentoxin: structural mechanism of action.

Genetic engineering of aquatic plants.

National Center for Bioinformatic-Genetic Infrastructure.

Developing computational methods for using and identifying protein motifs and applying them for the analysis of particular protein families.