• Picture of Prof. Orly Reiner

    Prof. Orly Reiner

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    Formation of the brain structure in human is a complex process. One of the most striking features of the human brain is characteristic convolutions. These convolutions are lacking in a severe human brain malformation known as lissencephaly (smooth brain).
    Identification of genes that are downstream to Lis1 mutation using microarray technology.
    Study of LIS1 and DCX functions through characterization of protein interactions
    Analysis of the developmental function of LIS1, DCX and Doublecortin-like-kinase using gene targeting in the mouse.
    Functional Analysis of Genes Involved in Lissencephaly.

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  • Prof. Yitzhak Frishman

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    Confinement and screening.
    Collaboration with:  Jacob Sonnenschein
    Non-abelian gauge theories.
    Collaboration with:  Marek Karliner, Jacob Sonnenschein
    From current to constituent quarks.
    Collaboration with:  Marek Karliner
  • Picture of Prof. Asher Friesem

    Prof. Asher Friesem

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    Diffractive Optical Elements and Planar Optics.
    Photonic Devices.
    Novel Laser Configurations.

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  • Picture of Prof. Michal Schwartz

    Prof. Michal Schwartz

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    The cross-talk between the immune and nervous systems – autoimmunity as a mechanism of tissue repair: Molecular, cellular, physiological and behavioral aspects.
    Immunological aspects of neuronal loss in neurodegenerative and mental disorders (Alzheimer’s, ALS, Huntingdon, Glaucoma).
    Spinal cord injury and repair
    Development of vaccination for neurodegenerative disorders.
    Neurogenesis (stem cells) and inflammation in the CNS.

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  • Picture of Prof. Zippora Shakked

    Prof. Zippora Shakked

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    Crystal structure and solution studies of DNA oligomers.
    Collaboration with:  Donald Crothers (Yale University)
    DNA regulatory elements
    DNA bending by adenine-thymine tracts
    Structural and biochemical studies of proteins involved in transcriptional regulation.
    The tumor-suppressor protein p53 and its interaction with DNA and the basal transcription machinery
    The leukemia-related RUNX1(AML1) transcription regulator

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  • Picture of Prof. Irun R. Cohen

    Prof. Irun R. Cohen

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    Autoimmune T cells and tissue maintenance in the nervous system
    Collaboration with:  M. Schwartz
    Autoimmunity to hsp60 and the development of subunit vaccines against infectious diseases.
    Regulation of immune inflammation by small carbohydrate molecules
    Collaboration with:  O. Lider
    Autoimmunity to p53 and the development of systemic lupus erythematosus
    Collaboration with:  V. Rotter
    Autoimmune diabetes: Pathogenesis and immune therapy.

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  • Picture of Prof. Michel Revel

    Prof. Michel Revel

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    Applications of IL-6 Chimera and Interferon-beta in neurology, hematopoiesis, and oncology.
    Collaboration with:  J. Chebath
    Interleukin-6 Chimera, a superactivator of the gp130 receptor system: role in nerve myelination, neuroprotection and in the development of neuro-glial cells from embryonic tissues and stem cells.
    Collaboration with:  J. Chebath
    Transdifferentiation of neural crest cell derived melanoma into myelinating Schwann cell. Genes controlling cell growth, differentiation, melanogenesis and synthesis of myelin proteins.
    Collaboration with:  J. Chebath
  • Picture of Prof. Abraham Arcavi

    Prof. Abraham Arcavi

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    Research on cognitive characteristics of non academically oriented math students.
    Collaboration with:  Dr. Ronnie Karsenty
    Design of curriculum materials as a research based activity
    Collaboration with:  Dr. Sue Magidson
    Long-term design of a new curriculum for grades 10, 11 and 12 for non-academically oriented students.
    Collaboration with:  Dr. Nurit Hadas

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  • Picture of Prof. Varda Rotter

    Prof. Varda Rotter

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    Molecular mechanisms controlling the expression of p53 in normal cells and its deregulation in cancer cells
    Involvement of p53 in cell differentiation and apoptosis: <I>in vivo</I> and in vitro models.
    Cellular proteins that specifically complex with the p53 protein.
    Cellular proteins that are induced upstream or downstream to the p53 protein following genotoxic stress.

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  • Picture of Prof. David Milstein

    Prof. David Milstein

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    Organometallic chemistry and catalysis
    Bond activation by electron-rich transition metal complexes.
    Rational design of homogeneous catalysis and synthetic methodology based on transition metal complexes.
    Impact of molecular order on catalysis and reactivity.
    Generation and stabilization of elusive (potentially biologically active) molecules

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