2024 research activities
Overview
Plants offer the world its only renewable resource of foods, alternative energy and biotherapeutic compounds. Plants have highly sophisticated short and long-term adaptive mechanisms to the environment as a result of the simple fact that they cannot alter their location during environmental change. Basic understanding of how plants react to the environment and why they grow the way they do are central to devising a rational approach to address three important global challenges, namely to secure more and healthier food, to develop novel plant-based products associated with biotherapeutics and to produce alternative energy resources in the form of biofuels. Research activities in the Department of Plant Sciences are associated with all of the above-mentioned global challenges and range from studies on the function and regulation of isolated genes to their interactive behavior in the context of the whole plant. We have developed extensive in-house genomic, bioinformatics and transgenic infrastructure that enables us to isolate novel genes by gene trapping, knockout or map-based cloning. Cloned genes are manipulated and studied by transgenic analysis to establish their potential in the whole plant. Our research as listed below integrates methodologies of molecular biology, protein modeling, genomics, metabolomics, bioinformatics, system biology, genetics, biochemistry and physiology.
Harnessing light energy and energy transduction in the plant cell: Research is carried out on the basic biophysical phenomenon of photon absorption by chlorophyll through transduction of this energy to ATP and the regulation of energy flux by the plant redox state.
Adaptive response in the plant to the biotic and abiotic environment: Molecular mechanisms that drive the cellular response are investigated under environmental perturbation. Research is directed in understanding the elements that play a role in the recognition of pathogens and the subsequent mounting of plant defense responses as well as in the response of plants to abiotic stresses, such as salt stress.
Plant metabolism and growth: Research is centered around elucidating regulatory metabolic networks for production of essential primary and secondary metabolites as well as understanding gene expression and hormonal networks that control plant metabolism, growth, reproduction and productivity.
Plant genome organization: Molecular tools have been developed to examine the fluidity of the plant genome, as described by transposon element, and the evolution of polyploid plants.
ScientistsShow details
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Prof. Asaph Aharoni
Genetic Regulation of Metabolic Pathways and its Co-ordination with Developmental and Stress Response Programs in Plant BiologyThe Primary-Secondary Metabolism InterfaceRegulation of Plant Surface FormationRegulation of Secondary Metabolism Associated Metabolic PathwaysPlant and Yeast MetabolomicsRiboswitches in Plants: Post Transcriptional Regulators of Metabolic Pathways
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Prof. Marvin Edelman
Duckweed biotechnologyCollaboration with: Barak Cohen, Ron VunshVolumetric growth of WolffiaPolyploidization of duckweeds for biomass increase and metabolic vigorMutagenesis from photoautotrpphy to photoheterotrophyTransgenic duckweed for veterinary productsGenomic analysis of calcium dependent protein kinases in duckweeds
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Prof. Moshe Feldman
Wheat genetics and evolutionCollaboration with: Prof. Avi LevyNone
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Prof. Robert Fluhr
Plant Response to Environmental StressReactive oxygen species in plant stress responseCellular REDOX stateGene expression networks in abiotic and biotic stressOxylipins, singlet oxygen and lipidomics of the osmotic stress response in rootsSinglet oxygen production in mutants, during photosynthesis and by natural photosensitizers and the resultant modification of RNA to yield translational arrest
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Dr. Assaf Gal
Morphogenesis of biological materailsUsing cryo electron microscopy for in-cell analysis of mineral formation.The role of liquid-liquid phase separation in biological mineralization.Silica formation in diatoms, from intracellular condensation of silica to morphogenesis of the cell-wall structure.Mechanisms of calcium carbonate precipitation by coccolithophores.
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Prof. Gad Galili
Association of metabolism and cell biology with plant development and response to stressCollaboration with: Zevulun Elazar, Aviah Zilberstein, Rachel Amir, Yoram Kapulnik, Alisaider FernieGene expression programs and metabolic networks associated with seed maturation and germinationMetabolic engineering of high-lysine plantsGenetic, genomic and bioinformatics approaches to elucidate metabolic networks in plantsRegulatory interactions between primary and secondary metabolism of plantsCell biology and physiology of autophagy-associated processes in plants
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Prof. Jonathan Gressel
Developing slow release herbicide formulationsCollaboration with: Michael BurnetDesigning tandem constructs to mitigate gene flow from transgenic crops to weeds
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Dr. Tamir Klein
Tree carbon metabolismTree-Tree root carbon transferWhole-tree carbon balanceTree-mycorrhiza interactionStarch metabolism in woody tissuesTree water transportTree drought resistanceXylem recovery from embolismThe role of aquaporins in woody tissues
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Prof. Ron Milo
Quantifying the AnthropoceneAnthropomassGlobal mammalian biomassGlobal arthropod biomassCell Biology by the NumbersCOVID-19Cellular turnoverDesign principles in energy and carbon fixationSynthetic autotrophyThe C1 economy
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Prof. Avigdor Scherz
Quantification of atoms, groups and molecules electronegati using metal substituted bacteriochlorophylls and application to chemical reactivity.Resolving the forces which drive membrane protein assembly.The mechenism behind generation of reactive oxygen species (ROS) by illuminating novel bacteriochlorophyll derivatives and their application in photodynamic therapy (PDT) of tumors.
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Prof. Assaf Vardi
The ecological and evolutionary role of programmed cell death in single-celled marine photosynthetic microorganismsThe role of infochemicals and their regulation of cell fate and cell-cell interactions in marine photosynthetic microorganismsSensing Environmental Stress and Acclimation Strategies in Marine AlgaeCell Signaling Pathways and their role in the Chemical Arms Race during Algal Host-Virus and Predator-Prey interactions
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