Department of Molecular Genetics
Postdoc position
Intracellular and intercellular RNA trafficking
Department of Molecular Genetics
PhD position
Intracellular and intercellular mRNA trafficking
Department of Condensed Matter Physics
Postdoc position
Post doc position opening in the semiconductor nanowires, molecular beam epitaxy growth laboratory of the Department of Condensed Matter Physics. The research focuses on advanced nanowire materials and structures for quantum research studies. The studies include growth and characterization by SEM, TEM and EDAX in close collaboration with the STM group of Prof Haim Beidenkopf.
Dr. Hadas Shtrikman
Department of Condensed matter Physics
Hadas.shtrikman@Weizmann.ac.il
Department of Chemical and Biological Physics
PhD position
We are looking for motivated students to join our group for the projects related to the solid-gas interfaces and fundamental catalysis, especially the CO2 hydrogenation reaction on various oxides. You will be working with a variety of surface-sensitive spectroscopy, microscopy, and scattering techniques.
Department of Chemical and Biological Physics
PhD position
We are looking for motivated students to join our group for the projects related to the electrochemical oxygen evolution reaction (OER), oxygen reduction reaction (ORR), and CO2 reduction reaction (CO2RR). You will be part of a team that designs and builds special reactor cells for scrutinising the surface chemistry of model catalysts under reaction conditions.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 2nd,3rd
Mechanisms of neuronal growth and regeneration
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Size matters, especially in neurons. Differentiated cells in higher eukaryotes exhibit a wide variety of shapes and sizes, while maintaining defined size ranges within cell subtypes. How do they do that? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. We are working on mechanisms of cell length and size sensing in neurons and other large cells, and how these mechanisms control growth and regeneration. People can integrate to a range of projects within this theme. For general information on our research please see the group home page at http://www.weizmann.ac.il/Biomolecular_Sciences/Fainzilber/ . Please note that research in our group requires work in animal models (mice, rats).
Department of Biomolecular Sciences
MSc position
Size sensing and growth control in neurons
More Information about MSc position
Size matters, especially in neurons. Differentiated cells in higher eukaryotes exhibit a wide variety of shapes and sizes, while maintaining defined size ranges within cell subtypes. How do they do that? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. We are working on mechanisms of cell length and size sensing in neurons and other large cells, and how these mechanisms control growth and regeneration. People can integrate to a range of projects within this theme. For general information on our research please see the group home page at http://www.weizmann.ac.il/Biomolecular_Sciences/Fainzilber/ . Please note that research in our group requires work in animal models (mice, rats).
Department of Biomolecular Sciences
Postdoc position
Size and growth control in neurons and other large cells - do cells sense their own size and how can they do that?
More Information about Postdoc position
Size matters, especially in neurons. Differentiated cells in higher eukaryotes exhibit a wide variety of shapes and sizes, while maintaining defined size ranges within cell subtypes. How do they do that? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. We are working on mechanisms of cell length and size sensing in neurons and other large cells, and how these mechanisms control growth and regeneration. People can integrate to a range of projects within this theme. For general information on our research please see the group home page at http://www.weizmann.ac.il/Biomolecular_Sciences/Fainzilber/ . Please note that research in our group requires work in animal models (mice, rats).
Department of Biomolecular Sciences
PhD position
Size and growth control in neurons and other large cells - do cells sense their own size and how can they do that?
More Information about PhD position
Size matters, especially in neurons. Differentiated cells in higher eukaryotes exhibit a wide variety of shapes and sizes, while maintaining defined size ranges within cell subtypes. How do they do that? Genome expression must be matched to different cell sizes, with rapidly growing cells likely requiring higher transcriptional and translational output than cells in slow growth or maintenance phase. Neurons exhibit the greatest size differences of any class of cells, with process lengths ranging from a few microns in central interneurons to a meter in human peripheral neurons, and even longer in larger mammals. We are working on mechanisms of cell length and size sensing in neurons and other large cells, and how these mechanisms control growth and regeneration. People can integrate to a range of projects within this theme. For general information on our research please see the group home page at http://www.weizmann.ac.il/Biomolecular_Sciences/Fainzilber/ . Please note that research in our group requires work in animal models (mice, rats).
Department of Chemical and Structural Biology
PhD position
Investigating the function of topological changes in membrane-crossing viral proteins.
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Please contact for additional details
Department of Chemical and Structural Biology
MSc position
Structural studies on viral/host interactions
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Please contact for additional details.
Department of Physics of Complex Systems
PhD position
Theoretical research in turbulence theory using the methods of quantum field theory.
Prefer somebody with MSc in field theory.
Department of Particle Physics and Astrophysics
PhD position
Theoretical high energy physics: string theory, field theory, gravity, black holes, relations to stat. mech., condensed matter physics and quantum chaos.
Department of Particle Physics and Astrophysics
MSc position
Theoretical high energy physics: string theory, field theory, gravity, black holes, relations to stat. mech., condensed matter physics and quantum chaos.
Department of Earth and Planetary Sciences
MSc position
Theoretical/numerical modelling, and laboratory experiments, to investigate a wide range of physical and biogeochemical transport processes in geological materials and other porous materials.
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A variety of tools from physics, mathematics and chemistry are integrated in our theoretical/numerical and experimental studies. Our projects range from analysis of fluid flow and chemical transport in geological formations, to development of physico-chemical methods to remediate water polluted by organic and metal compounds, to theoretical analyses of transport processes using methods of statistical physics. Methods to analyze transport and diffusion can be applied also to tissues and cells.
Department of Earth and Planetary Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Theoretical/numerical modelling, and laboratory experiments, to investigate a wide range of physical and biogeochemical transport processes in geological materials and other porous materials.
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A variety of tools from physics, mathematics and chemistry are integrated in our theoretical/numerical and experimental studies. Our projects range from analysis of fluid flow and chemical transport in geological formations, to development of physico-chemical methods to remediate water polluted by organic and metal compounds, to theoretical analyses of transport processes using methods of statistical physics. Methods to analyze transport and diffusion can be applied also to tissues and cells.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 3rd
Membrane protein folding and quality control
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Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. For more details, visit http://www.weizmann.ac.il/Biomolecular_Sciences/Fluman
Department of Biomolecular Sciences
PhD position
Membrane protein folding and quality control
More Information about PhD position
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. For more details, visit http://www.weizmann.ac.il/Biomolecular_Sciences/Fluman
Department of Biomolecular Sciences
MSc position
Membrane protein folding and quality control
More Information about MSc position
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. For more details, visit http://www.weizmann.ac.il/Biomolecular_Sciences/Fluman
Department of Biomolecular Sciences
Postdoc position
Membrane protein folding and quality control
More Information about Postdoc position
Membrane proteins make up a quarter of the proteome of every living organism and participate in nearly every biological process. We are interested in the fascinating process of how these proteins get produced, fold, and assemble in cells. The questions we address are: How do proteins fold in the membranes of living cells? How do the dynamic features of unfolded proteins assist in this process? How do cellular factors recognize membrane proteins that failed to fold and need to be cleared? The lab combines biochemical, cell biology, genetic and computational tools. For more details, visit http://www.weizmann.ac.il/Biomolecular_Sciences/Fluman
Department of Particle Physics and Astrophysics
MSc position
MSc positions in theoretical particle/astro physics.
https://www.weizmann.ac.il/particle/Blum/home
Department of Chemical and Biological Physics
Postdoc position
Scientists are being sought for developing new experiments in the area of electron-enhanced nuclear magnetic resonance. This so-called dynamic nuclear polarization (DNP) NMR experiment subjects electrons in the sample to microwave irradiation, and then uses the ensuing nuclear polarization enhancement to open new analytical and metabolic frontiers in NMR. Topics involved in this research will include developing new forms of quantum control between spins to enable a more efficient electron-->nuclear polarization transfer, automation, cryogenics, and the design and construction of radiofrequency and microwave components. Programming experience also required. Applications of this project to solve both analytical and biophysical problems are also envisioned.
Department of Chemical and Biological Physics
Postdoc position
Scientists with interest in working with magnetic resonance are sought for the development of new metabolic imaging experiments. The student will work on understanding the physics and performing an array of new MRI experiments on high end scanners, and apply these in the detection of small tumors, and in the evaluation of chemotherapeutic and biological treatments. The student will be advised by physicists, chemists and biologists/clinicians in this project
Department of Chemical and Biological Physics
MSc rotation
Available Rotations: 3rd
Students are being sought for developing new experiments in the area of electron-enhanced nuclear magnetic resonance. This so-called dynamic nuclear polarization (DNP) NMR experiment subjects electrons in the sample to microwave irradiation, and then uses the ensuing nuclear polarization enhancement to open new analytical and metabolic frontiers in NMR. Students are being sought that will participate in these experiments, and assist in programming the spin physics involved in them
Department of Chemical and Biological Physics
MSc position
Students are being sought for developing new experiments in the area of electron-enhanced nuclear magnetic resonance. This so-called dynamic nuclear polarization (DNP) NMR experiment subjects electrons in the sample to microwave irradiation, and then uses the ensuing nuclear polarization enhancement to open new analytical and metabolic frontiers in NMR. Topics involved in this research will include developing new forms of quantum control between spins to enable a more efficient electron-->nuclear polarization transfer, automation, cryogenics, and the design and construction of radiofrequency and microwave components. Programming experience also required. Applications of this project to solve both analytical and biophysical problems are also envisioned.
Department of Chemical and Biological Physics
PhD position
Students are being sought for developing new experiments in the area of electron-enhanced nuclear magnetic resonance. This so-called dynamic nuclear polarization (DNP) NMR experiment subjects electrons in the sample to microwave irradiation, and then uses the ensuing nuclear polarization enhancement to open new analytical and metabolic frontiers in NMR. Topics involved in this research will include developing new forms of quantum control between spins to enable a more efficient electron-->nuclear polarization transfer, automation, cryogenics, and the design and construction of radiofrequency and microwave components. Programming experience also required. Applications of this project to solve both analytical and biophysical problems are also envisioned.
Department of Chemical and Biological Physics
MSc position
Students with interest in working with magnetic resonance are sought for the development of new metabolic imaging experiments. The student will work on understanding the physics and performing an array of new MRI experiments on high end scanners, and apply these in the detection of small tumors, and in the evaluation of chemotherapeutic and biological treatments. The student will be advised by physicists, chemists and biologists/clinicians in this project
Department of Chemical and Biological Physics
PhD position
Students with interest in working with magnetic resonance are sought for the development of new metabolic imaging experiments. The student will work on understanding the physics and performing an array of new MRI experiments on high end scanners, and apply these in the detection of small tumors, and in the evaluation of chemotherapeutic and biological treatments. The student will be advised by physicists, chemists and biologists/clinicians in this project
Department of Biomolecular Sciences
PhD position
We are looking for a postdoctoral fellow to work on a new and exciting project on lipid complexity. There are many more lipids in cells and in cell membranes than once thought and this complexity has significant ramifications for understanding both the roles of lipids in the origin of life and also in modern cell function. A position is available for an enthusiastic candidate to work on lipids in the origin of life, lipid fine-tuning, and functional studies of lipid complexity. For publications and details see the lab web page at
https://www.weizmann.ac.il/Biomolecular_Sciences/Futerman/
More Information about PhD position
See short description
Department of Biomolecular Sciences
Postdoc position
We are looking for a postdoctoral fellow to work on a new and exciting project on lipid complexity. There are many more lipids in cells and in cell membranes than once thought and this complexity has significant ramifications for understanding both the roles of lipids in the origin of life and also in modern cell function. A position is available for an enthusiastic candidate to work on lipids in the origin of life, lipid fine-tuning, and functional studies of lipid complexity. For publications and details see the lab web page at
https://www.weizmann.ac.il/Biomolecular_Sciences/Futerman/
More Information about Postdoc position
See short description
Department of Plant and Environmental Sciences
PhD position
We are looking for extremely talented candidates to study the roles of dense mineral phases in the formation of biomaterials.
Department of Plant and Environmental Sciences
Postdoc position
We are looking for extremely talented candidates to use and develop state-of-the-art cryo electron microscopy techniques for the study of cellular mineralization.
Department of Particle Physics and Astrophysics
MSc position
M.Sc student working on analysis of large astrophysical data sets including development of new analysis methods
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I am looking for a student interested in working on large data sets that are now becoming available as part of the "data explosion" in astrophysics. Weizmann is a major world leader in this, both creating large data sets through our own observational work, as well as acting as a leading center curating large data sets from around the world on our systems. The focus of this project is on analysis of large observational data sets of exploding stars (supernovae) which require development of new methodologies, and is likely to shed light on fundamental questions in astrophysics. The work would interface with more traditional observational work using telescopes in Israel and abroad, as well as with some aspects of computing and mathematics.
Department of Particle Physics and Astrophysics
MSc position
M.Sc position in observational astrophysics: observing stars as they explode
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I am looking for a student interested in working on a search for supernovae - exploding stars - which we can find using our new observatory in Neot Smadar. The unique aspect of this project is the capability of the new observatory to find such explosions almost "as they happen" as it monitors the sky very frequently - several times every night. This could lead to new discoveries as the capability is novel. The project includes significant hands-on work related to the new observatory, data analysis, as well as work with large follow-up telescopes abroad.
Department of Particle Physics and Astrophysics
Postdoc position
Postdoctoral work on data from SoXS, a new spectrograph with novel capabilities
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I am looking for a postdoc interested in leading the work here at Weizmann on data from the new SoXS instrument, a very efficient, broad-band and high resolution spectrograph to be commissioned on the 3.6m NTT telescope in Chile in the coming year. The unique capabilities of this instrument open up new windows for discovery, and Weizmann is a leading institution in the consortium building and operating this instrument.
Department of Particle Physics and Astrophysics
PhD position
Ph.D thesis work in observational astrophysics with a focus on early spectroscopy of exploding stars
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I am looking for a student interesting in observational work focussed on observations, in particular spectroscopic, of exploding stars (supernovae), very shortly (within hours or days) of the explosion. The project includes analysis of a large set of data already in hand (the largest and best of its kind in the world; in collaboration with an experienced postdoc) as well as work toward obtaining even better data with the new spectroscopic array being developed in our Neot Smadar Observatory.
Department of Brain Sciences
MSc rotation
Available Rotations: 2nd,3rd
Studying tactile perception in mice using cutting edge methods, including cellular physiology Neuropixels, 2P imaging and other approaches.
Department of Brain Sciences
Postdoc position
Studying tactile perception in mice using cutting edge methods, including cellular physiology Neuropixels, 2P imaging and other approaches.
Department of Brain Sciences
PhD position
Studying tactile perception in mice using cutting edge methods, including cellular physiology Neuropixels, 2P imaging and other approaches.
Department of Particle Physics and Astrophysics
MSc position
We are looking for students interested in integrating their Physics skills with Math skills, particularly in the Machine Learning discipline. Students should be interested in both High Energy Physics and Machine Learning.
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We develop Machine Learning architectures to solve complicated problems in High Energy Physics. Our group is also active in the ATLAS experiment at CERN, implementing Machine Learning solutions to the search for New Physics. We also invest a lot of effort in solving problems related to Big Data management and analysis of collisions Data.
Department of Particle Physics and Astrophysics
PhD position
We are looking for students interested in integrating their Physics skills with Math skills, particularly in the Machine Learning discipline. Students should be interested in both High Energy Physics and Machine Learning.
More Information about PhD position
We develop Machine Learning architectures to solve complicated problems in High Energy Physics. Our group is also active in the ATLAS experiment at CERN, implementing Machine Learning solutions to the search for New Physics. We also invest a lot of effort in solving problems related to Big Data management and analysis of collisions Data.
Department of Physics of Complex Systems
PhD position
Fiber-optical analogue of the event horizon
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We are looking for a PhD student to join our experiment on probing the physics of the event horizon using nonlinear fiber optics.
Department of Physics of Complex Systems
MSc position
Fiber-optical analogue of the event horizon.
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Join our research on the theory and experiment of Hawking radiation in fiber optics.
Department of Molecular Cell Biology
Postdoc position
We are looking for highly motivated post-doctoral fellow or research associate to an ERC funded project studying the "Biology of Ageing"
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We are looking for highly motivated post-doctoral fellow or research associate to an ERC funded project studying the "Biology of Ageing" at Weizmann Institute. The project is a collaboration of laboratories of Uri Alon, Tali Kimchi and Valery Krizhanovsky. It will combine cutting edge methods in molecular and cellular biology, behavioral neuroscience and system biology in mouse models. An expertise in behavioral neuroscience, molecular biology and mouse models is a plus.
Department of Particle Physics and Astrophysics
MSc position
We live in fortunate times, where there are still many fundamental unsolved problems in astrophysics, while technological progress allows new observations, which may make some of them solvable. Now is the time to attack the most puzzling challenges posed to us by the Universe.
Join Doron Kushnir's group to study explosions and extreme stars of the Universe. We use theoretical and computational tools to interpret state-of-the-art observations, aiming at resolving fundamental problems in astrophysics.
Department of Particle Physics and Astrophysics
Postdoc position
We live in fortunate times, where there are still many fundamental unsolved problems in astrophysics, while technological progress allows new observations, which may make some of them solvable. Now is the time to attack the most puzzling challenges posed to us by the Universe.
Join Doron Kushnir's group to study explosions and extreme stars of the Universe. We use theoretical and computational tools to interpret state-of-the-art observations, aiming at resolving fundamental problems in astrophysics.
Department of Particle Physics and Astrophysics
PhD position
We live in fortunate times, where there are still many fundamental unsolved problems in astrophysics, while technological progress allows new observations, which may make some of them solvable. Now is the time to attack the most puzzling challenges posed to us by the Universe.
Join Doron Kushnir's group to study explosions and extreme stars of the Universe. We use theoretical and computational tools to interpret state-of-the-art observations, aiming at resolving fundamental problems in astrophysics.
Department of Molecular Genetics
MSc rotation
Available Rotations: 1st,2nd,3rd
How do fusing cells known when to stop fusing?
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Cell-cell fusion is an uncommon but essential process in our bodies. While a lot is known about how cell fusion initiates, very little is known about how the process is regulated and eventually terminated when "enough" fusion has occurred. We study these issues in osteoclasts, multi-nucleated cells that degrade bone and which are formed by fusion of monocyte precursor cells. Our studies focus on fusion of osteoclasts from wild-type mice and also from mice carrying mutated forms of sorting nexin 10 (SNX10), which fuse continuously and uncontrollably. Join us to characterize the molecular and cellular mechanisms that regulate osteoclast fusion!
Department of Molecular Genetics
MSc rotation
Available Rotations: 1st,2nd,3rd
Formation and function of osteoclasts (bone resorbing cells) in vitro and in vivo, in health and in disease.
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Bone degradation by specialized cells (osteoclasts) is a normal process and helps maintain normal bone structure and function; it's absence, as in the genetic disease osteopetrosis, is lethal. Our group searches for proteins that participate in forming these critical cells and direct their activity, using advanced molecular, cellular, and whole-organism approaches.
Department of Molecular Genetics
PhD position
Formation and function of osteoclasts (bone resorbing cells) in vitro and in vivo, in health and in disease.
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Bone degradation by specialized cells (osteoclasts) is a normal process and helps maintain normal bone structure and function; it's absence, as in the genetic disease osteopetrosis, is lethal. Our group studies how specific proteins (tyrosine phosphatases and others) affect production and function of these critical cells, using advanced molecular, cellular, and whole-organism approaches.
Department of Molecular Genetics
PhD position
PhD Joint Program Centre National de la Recherche (CNRS)-Weizmann Institute of Science (WIS) - 2022-2025
Two Ph.D. grants (3-year duration, starting Oct. 2022) one from Hornstein lab (WIS) and one from Monchaud lab (CNRS) have been awarded to our French/Israeli consortium, one for each country, to develop a chemical biology program aiming at deciphering the biology of a peculiar RNA structure referred to as G-quadruplex RNA (or G4-RNA) in human cells and diseases (chiefly cancers and neuropathology). The position at WIS (in Rehovot, IS) has been filled; the position at CNRS (in Dijon, FR) is still open.
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The functional relevance of G4-RNA in human cells has progressed at a pace dictated by the advances in chemical biology techniques and methodology. The prevalence of G4-RNA in human cells has been investigated in vitro thanks to rG4-seq combining ligand-stabilized G4-RNA, reverse transcriptase stalling and sequencing (cf. C. K. Kwok et al., Nat. Methods 2016, 13, 841) while G4RP-seq was developed for in vivo investigations (our work), being based on G4 isolation using the small molecule BioTASQ followed by sequencing (cf. S. Y. Yang et al., Nat. Commun. 2018, 9, 4730 & Nat. Protoc. 2022, 17, 870).
In the present project, we will go a step forward, combining sequencing and proteomics, focusing on the involvement of G4-RNA in stress response. Stress granules (SGs) are transient, cytoplasmic membraneless condensates, composed of proteins and untranslated mRNAs. Although RNA-binding proteins that may control G4-RNA were recently speculated to regulate SG assembly, it is unknown whether G4-RNA play a direct regulatory role in SG biology. The Hornstein lab (WIS, Rehovot, IS) is an expert of RNA biology and SG proteomics, especially in the framework of neurodegenerative diseases (cf. Marmor-Kollet et al., Mol. Cell. 2020, 80, 876); the Monchaud/Valverde lab (ICMUB, Dijon, FR) is an expert of the design of molecular tools aiming at deciphering the prevalence and functional relevance of G4-RNA in human cells. The Ph.D. position available in France will be focused on the synthesis and characterization of chemical biology tools (TASQ derivatives, cf. Stefan & Monchaud, Nat. Rev. Chem. 2019, 3, 650) to study G4-RNA impact on SG composition and dynamics and characterize G4-RNA binding proteins in the aim of better understanding SG biology.
The position is thus open to a chemist by training eager to work in a chemical biology research program, that is, at the interface between chemistry, biophysics, cellular biology and optical imaging, and interested to be part of an international collaboration in which short missions in both countries will be regularly planned.
-> Interested? Please contact david.monchaud@cnrs.fr; Ibai.Valverde@u-bourgogne.fr
Department of Biomolecular Sciences
PhD position
We are inviting students interested in evolution, microbial communities, gene-phenotype relations and their interaction with past and current environments to join us.
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Our lab utilises techniques such as: microfluidics, CRISPR, genetic barcoding, fluorescence and automated microscopy to study basic questions in the evolution of communities, using yeast as a model.
Department of Biomolecular Sciences
Postdoc position
We are inviting students interested in evolution, microbial communities, gene-phenotype relations and their interaction with past and current environments to join us.
More Information about Postdoc position
Our lab utilises techniques such as: microfluidics, CRISPR, genetic barcoding, fluorescence and automated microscopy to study basic questions in the evolution of communities, using yeast as a model.
Department of Biomolecular Sciences
MSc position
We are inviting students interested in evolution, microbial communities, gene-phenotype relations and their interaction with past and current environments to join us.
More Information about MSc position
Our lab utilises techniques such as: microfluidics, CRISPR, genetic barcoding, fluorescence and automated microscopy to study basic questions in the evolution of communities, using yeast as a model.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Our lab utilises techniques such as: microfluidics, CRISPR, genetic barcoding, fluorescence and automated microscopy to study basic questions in the evolution of communities, using yeast as a model.
Department of Particle Physics and Astrophysics
MSc position
Plasma Physics, Spectroscopy, Plasma Diagnostics, Atomic Physics
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We study processes in plasmas subjected to high-energy deposition: conversion of electric energy to heat and radiation, turbulence, fast penetration of magnetic fields into plasmas, and plasma rotation. For diagnosing the plasma we develop fast, high-resolution spectroscopy of radiation in the visible, U.V., vacuum UV, and x-ray regions. We have close collaboration with major universities and institutions in the US and Europe.
Department of Particle Physics and Astrophysics
PhD position
Plasma Physics, Spectroscopy, Plasma Diagnostics, Atomic Physics
More Information about PhD position
We study processes in plasmas subjected to high-energy deposition: conversion of electric energy to heat and radiation, turbulence, fast penetration of magnetic fields into plasmas, and plasma rotation. For diagnosing the plasma we develop fast, high-resolution spectroscopy of radiation in the visible, U.V., vacuum UV, and x-ray regions. We have close collaboration with major universities and institutions in the US and Europe.
Department of Particle Physics and Astrophysics
Postdoc position
Plasma Physics, Spectroscopy, Plasma Diagnostics, Atomic Physics
More Information about Postdoc position
We study processes in plasmas subjected to high-energy deposition: conversion of electric energy to heat and radiation, turbulence, fast penetration of magnetic fields into plasmas, and plasma rotation. For diagnosing the plasma we develop fast, high-resolution spectroscopy of radiation in the visible, U.V., vacuum UV, and x-ray regions. We have close collaboration with major universities and institutions in the US and Europe.
Department of Immunology and Regenerative Biology
PhD position
We are interested in understanding what kind of activities can long RNAs, including both long noncoding RNAs (lncRNAs) and mRNAs, or fragments thereof, carry out in mammalian cells. We particularly interested in the question of how these activities are encoded in the genomic sequences of these genes, how they are related to the secondary structures they adopt in cells, how mutations in lncRNA genes or in noncoding regions in mRNA UTRs affect their function, and how to exploit all this knowledge to design better therapeutic approaches for both rare and common diseases. We are addressing these questions using a combination of both experimental biology (including molecular biology, cell biology, stem cell biology, and neurobiology) and computational biology/bioinformatics. PhD projects focused on specific projects related to these questions are available.
Department of Immunology and Regenerative Biology
MSc position
We are interested in understanding what kind of activities can long RNAs, including both long noncoding RNAs (lncRNAs) and mRNAs, or fragments thereof, carry out in mammalian cells. We particularly interested in the question of how these activities are encoded in the genomic sequences of these genes, how they are related to the secondary structures they adopt in cells, how mutations in lncRNA genes or in noncoding regions in mRNA UTRs affect their function, and how to exploit all this knowledge to design better therapeutic approaches for both rare and common diseases. We are addressing these questions using a combination of both experimental biology (including molecular biology, cell biology, stem cell biology, and neurobiology) and computational biology/bioinformatics. PhD projects focused on specific projects related to these questions are available.
Department of Immunology and Regenerative Biology
Postdoc position
Experimental and computational approaches for studying the biology of long RNAs.
More Information about Postdoc position
We are interested in understanding what kind of activities can long RNAs, including both long noncoding RNAs (lncRNAs) and mRNAs, or fragments thereof, carry out in mammalian cells. We particularly interested in the question of how these activities are encoded in the genomic sequences of these genes, how they are related to the secondary structures they adopt in cells, how mutations in lncRNA genes or in noncoding regions in mRNA UTRs affect their function, and how to exploit all this knowledge to design better therapeutic approaches for both rare and common diseases. We are addressing these questions using a combination of both experimental biology (including molecular biology, cell biology, stem cell biology, and neurobiology) and computational biology/bioinformatics. Postdoctoral positions focused on specific projects related to these questions are available.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Understanding the evolution of variants of SARS-CoV-2, and drug development that will be effective against future variants.
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Since the beginning of the COVID-19 pandemic, we are actively investigating the evolution of the different variants, and how to make drugs that will combat them. We have published multiple papers in high impact journals on the subject
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Investigating protein-protein interactions and interferon actions
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Our research group is interested in investigating all aspects of protein-protein interactions, from their biophysical nature to their role in signaling within the cell. As our cellular model system we are investigating the multiple activities of type I interferons.
Department of Molecular Cell Biology
PhD position
Circuit remodeling - molecules, circuits and behavior
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Neuronal remodeling is an essential process used to sculpt the mature nervous system in vertebrates and invertebrates. One major mechanism is axon pruning in which neurons eliminate specific sections of their axons in a stereotypic manner. Not much is know about the molecular mechanisms that underlie this process. Defects in pruning may result in neurological conditions such as synesthesia or autism and the molecular mechanisms involved in axon pruning during development are also involved in axon fragmentation during neurodegenerative diseases such as Alzheimer's, Parkinson's and ALS. Therefore, uncovering the molecular mechanisms underlying axon pruning during development should increase our knowledge more broadly on axon fragmentation during development, disease and after injury. We are studying this process in the fly as it is an awesome genetic model organism with cutting edge techniques that enable us to mutate and visualize single neurons within a whole brain. We are looking for bright and enthusiastic rotation students to join and push forward one of our ongoing research projects. Looking forward to see you!
Department of Biomolecular Sciences
MSc position
We have open positions for Ph.D. candidates interested in mechanisms of channel regulation by GPCRs using, but not limited to, computational (molecular dynamics), electrophysiological, molecular and/or optical methodologies.
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G protein-coupled receptors (GPCRs) are the largest gene family in the human genome. Their role is to translate chemical information into cellular responses, like olfactory processing, neuronal activity modulation, and hormone actions or regulating blood pressure among many. Their cellular effectors can range from various enzymes to ion channels. Interestingly, nature has designed the GPCR as a major target for many natural compounds and the pharmaceutical industry has focused its attention on designing various agonists and antagonists to treat various illnesses. In the lab, we focus on the regulation of ion channels by GPCRs with the main focus on the regulation of potassium channels. This form of regulation comprises one of the major mechanisms in controlling slow synaptic inhibition in the brain, a process when compromised leads to seizures ataxia, and many other neuronal abnormalities.
The lab's interests span from a molecular understanding of channel regulating mechanisms at the single molecule level to animal behavior using various electrophysiological, molecular, imaging, and computational tools.
We seek highly motivated students to join us in this very exciting scientific journey.
Department of Biomolecular Sciences
Postdoc position
We have open positions for Ph.D. candidates interested in mechanisms of channel regulation by GPCRs using, but not limited to, computational (molecular dynamics), electrophysiological, molecular and/or optical methodologies.
More Information about Postdoc position
G protein-coupled receptors (GPCRs) are the largest gene family in the human genome. Their role is to translate chemical information into cellular responses, like olfactory processing, neuronal activity modulation, and hormone actions or regulating blood pressure among many. Their cellular effectors can range from various enzymes to ion channels. Interestingly, nature has designed the GPCR as a major target for many natural compounds and the pharmaceutical industry has focused its attention on designing various agonists and antagonists to treat various illnesses. In the lab, we focus on the regulation of ion channels by GPCRs with the main focus on the regulation of potassium channels. This form of regulation comprises one of the major mechanisms in controlling slow synaptic inhibition in the brain, a process when compromised leads to seizures ataxia, and many other neuronal abnormalities.
The lab's interests span from a molecular understanding of channel regulating mechanisms at the single molecule level to animal behavior using various electrophysiological, molecular, imaging, and computational tools.
We seek highly motivated students to join us in this very exciting scientific journey.
Department of Biomolecular Sciences
PhD position
We have open positions for Ph.D. candidates interested in mechanisms of channel regulation by GPCRs using, but not limited to, computational (molecular dynamics), electrophysiological, molecular and/or optical methodologies.
More Information about PhD position
G protein-coupled receptors (GPCRs) are the largest gene family in the human genome. Their role is to translate chemical information into cellular responses, like olfactory processing, neuronal activity modulation, and hormone actions or regulating blood pressure among many. Their cellular effectors can range from various enzymes to ion channels. Interestingly, nature has designed the GPCR as a major target for many natural compounds and the pharmaceutical industry has focused its attention on designing various agonists and antagonists to treat various illnesses. In the lab, we focus on the regulation of ion channels by GPCRs with the main focus on the regulation of potassium channels. This form of regulation comprises one of the major mechanisms in controlling slow synaptic inhibition in the brain, a process when compromised leads to seizures ataxia, and many other neuronal abnormalities.
The lab's interests span from a molecular understanding of channel regulating mechanisms at the single molecule level to animal behavior using various electrophysiological, molecular, imaging, and computational tools.
We seek highly motivated students to join us in this very exciting scientific journey.
Department of Physics of Complex Systems
PhD position
Context: laser plasma interaction at relativistic regime. Strong experimental component
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Laser plasma accelerators allow to produce the most extreme electric fields of TV/m that are revolutionarized accelerator physics. A critical limitation of laser driven Wakefield concept is that the velocity of the wave is getting slower when the trapped electrons are getting relativistic enough. To avoid such limitation we develop with spatio temporal coupling and special optic a solution that leads to luminal, sub or super- luminal wake of major interest for getting significant energy gain.
The purposes of the thesis is to explore all the benefits of such original approach using the unique 100 TW laser system at WIS.
Department of Physics of Complex Systems
Postdoc position
Experimental/Theory on application of laser plasma accelerator to radiotherapy
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The use of very high energy electron (250 MeV) as the one we currently produce at WIS, has been shown to improve cancer treatment. The aims of the work is to scale down the apparatus by optimising all the process in order to deliver such VHEE beam with a machine that has to be competitive with conventional RT machine and with a compact size.
Department of Physics of Complex Systems
PhD position
Laser plasma accelerators of electrons
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Experimental studies on relativistic laser matter interaction: applications to electrons acceleration
The goal of this research is to define a novel strategy for guiding intense laser in plasma to facilitate the obtention of high quality electron beam at GeV level
Department of Physics of Complex Systems
MSc position
Laser based electron accelerator
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Experimental work on the most powerful laser in Israel that aims to boost the electron energy to the GeV level
Department of Physics of Complex Systems
PhD position
Relativistic interaction at near critical density
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Interaction of intense laser pulse with dense plasma at near critical is new area of research that we can for the first time explored at WIS thanks to our recent development. Many new fundamental aspects are expected to be discovered. The new diagnostics and the new targets are now ready to probe non linear process such as filamentation, beam break up, soliton formation, etc.
Department of Earth and Planetary Sciences
Postdoc position
Develop and explore AI and Machine Learning architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
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Responsibilities:
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
Explore explainable AI approaches to gain a scientific understanding of the weather events' precursor processes and their physical patterns.
Identify and define unique challenges for AI in the field of remote sensing-driven extreme weather forecast models, and study novel solutions.
Explore the integration of fundamental physical and atmospherical theory (e.g., Navier–Stokes equations) within deep learning architectures.
Study unsupervised approaches for learning concise representations of large-scale spatio-temporal meteorological data sequences for various tasks, including memory compression, clustering, augmentation, and generative purposes.
The candidate is expected to advance the group's current AI capabilities and to be a source of knowledge for various machine learning and data science tasks carried out by other group members, including R&D projects of a drone-based system. Candidates should be passionate about Earth and planetary sciences, working in a small research team, and collaborating with researchers from other disciplines.
Minimum Qualifications:
- PhD in computer sciences/ physics/ environmental science/ engineering /statistics/ related fields
- Reach a theoretical understanding of deep learning and or statistical modeling.
- Proven experience in Python packages such as Scikit-learn, Pytorch, Tensorflow, etc.
- Proven independence, self-management, and self-learning skills
Preferred Background in:
- Experience in the analysis of spatio-temporal data/ remote sensing/ monitoring networks.
Department of Earth and Planetary Sciences
Postdoc position
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
More Information about Postdoc position
Responsibilities:
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
Explore explainable AI approaches to gain a scientific understanding of the weather events' precursor processes and their physical patterns.
Identify and define unique challenges for AI in the field of remote sensing-driven extreme weather forecast models, and study novel solutions.
Explore the integration of fundamental physical and atmospherical theory (e.g., Navier–Stokes equations) within deep learning architectures.
Study unsupervised approaches for learning concise representations of large-scale spatio-temporal meteorological data sequences for various tasks, including memory compression, clustering, augmentation, and generative purposes.
The candidate is expected to advance the group's current AI capabilities and to be a source of knowledge for various machine learning and data science tasks carried out by other group members, including R&D projects of a drone-based system. Candidates should be passionate about Earth and planetary sciences, working in a small research team, and collaborating with researchers from other disciplines.
Minimum Qualifications:
- PhD in computer sciences/ physics/ environmental science/ engineering /statistics/ related fields
- Reach a theoretical understanding of deep learning and or statistical modeling.
- Proven experience in Python packages such as Scikit-learn, Pytorch, Tensorflow, etc.
- Proven independence, self-management, and self-learning skills
Preferred Background in:
- Experience in the analysis of spatio-temporal data/ remote sensing/ monitoring networks.
Department of Earth and Planetary Sciences
PhD position
Investigation the biological and toxicological effects of SOA from on-road car emissions funded by the EU
More Information about PhD position
Description and lab research areas:
Our lab studies the health impacts of air pollution, the number one environmental cause of the global disease burden. This newly funded EU project ( ASVOLEE, Effects on Air quality of Semi-VOLatile Engine Emissions) involves studying cytotoxicity imposed by exposure to SOA particles formed from on-road cars under real driving conditions.
The project will use cultured cell models, together with big data analysis such as toxicology, RNA sequencing, and metabolomics analyses. Recent laboratory experience and basic molecular biology and biochemistry skills are an advantage. Through this new EU project, we will offer a dynamic and international collaboration between the Weizmann Institute of Science and other key laboratories in Europe. The work involves active collaborations between the participating groups and taking active roles in joint experimental campaigns, data analyses, paper writing, and weekly joint seminars, among other activities.
The target of this PhD/Post Doc research focuses on investigating the mechanisms (biological and toxicological effects) induced by collected SOA in field campaigns with advanced exposure models. In vitro exposure will focus on optimizing exposure of human epithelial lung cells and other tissue (liver, fat) cultures and developing differentiated 3D cell cultures and disease-oriented tissue models.
Required elements for research-based postdoc applications: Recent laboratory experience and basic molecular biology and biochemistry skills are an advantage. PhD in Chemistry, Biology, Biochemistry, Atmospheric sciences, or related fields.
Please send applications to Prof. Yinon Rudich, Department of Earth and Planetary Sciences, Weizmann Institute, Rehovot 76100, Israel
e-mail: yinon.rudich@weizmann.ac.il, Tel: 972 8 934 4237
Lab website: https://www.weizmann.ac.il/EPS/Rudich/
Department of Earth and Planetary Sciences
Postdoc position
Studying the Microbiome of the atmosphere.
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The atmospheric transport of microorganisms can affect the biodiversity and health of global ecosystems. However, the processes influencing airborne bacterial communities' abundance, composition, and dispersal are still not well understood. We study the aerial microbiome to better understand the structure, function, and ecological drivers of airborne communities transported by dust-plumes in the Eastern Mediterranean. We use state-of-the-art aerosol sampling techniques, Next-generation sequencing (NGS), molecular biology and bioinformatics tools.
We are looking for highly motivated and curious PhD students and PostDocs to join our team.
Required qualifications:
- MSc. or PhD. degree in microbial ecology, environmental genomics or related fields.
- Experience in DNA/RNA extraction techniques.
- Experience in bioinformatic/biostatistical pipelines using R or Python.
- Knowledge on the analysis and interpretation of microbial community genomics data.
The following additional qualifications will be advantageous:
- Background in bioaerosol research or related fields.
- Knowledge on molecular biology and microbiology techniques (i.e., genomic sequencing, qPCR, flow cytometry, cell culturing).
- The generation of NGS sequencing libraries.
Please contact:
Prof. Yinon Rudich
yinon.rudich@weizmann.ac.il
Department of Earth and Planetary Sciences
Weizmann Institute of Science
Department of Earth and Planetary Sciences
PhD position
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
More Information about PhD position
Develop and explore AI architectures for extreme weather events forecasting, driven by remote sensing and in-situ data, to replace theory-driven climate models.
Explore explainable AI approaches to gain a scientific understanding of the weather events' precursor processes and their physical patterns.
Identify and define unique challenges for AI in the field of remote sensing-driven extreme weather forecast models, and study novel solutions.
Explore the integration of fundamental physical and atmospherical theory (e.g., Navier–Stokes equations) within deep learning architectures.
Study unsupervised approaches for learning concise representations of large-scale spatio-temporal meteorological data sequences for various tasks, including memory compression, clustering, augmentation, and generative purposes.
The candidate is expected to advance the group's current AI capabilities and to be a source of knowledge for various machine learning and data science tasks carried out by other group members, including R&D projects of a drone-based system. Candidates should be passionate about Earth and planetary sciences, working in a small research team, and collaborating with researchers from other disciplines.
Minimum Qualifications:
- MSc in computer sciences/ physics/ environmental science/ engineering /statistics/ related fields
- Proven experience (theory and hands-on) in Statistical modeling/ machine learning / deep learning.
- Experience in developing research projects, from data acquisition through analysis to prediction.
- Proven independence, self-management, and self-learning skills
- Proven teamwork skills
Preferred Background in:
- Experience with Python packages such as Scikit-learn, Pytorch, Tensorflow, etc.
- Experience in the analysis of spatiotemporal data/remote sensing/
- monitoring networks.
- In-depth understanding of deep learning theory
Department of Earth and Planetary Sciences
PhD position
Studying the Microbiome of the atmosphere.
More Information about PhD position
The atmospheric transport of microorganisms can affect the biodiversity and health of global ecosystems. However, the processes influencing airborne bacterial communities' abundance, composition, and dispersal are still not well understood. We study the aerial microbiome to better understand the structure, function, and ecological drivers of airborne communities transported by dust-plumes in the Eastern Mediterranean. We use state-of-the-art aerosol sampling techniques, Next-generation sequencing (NGS), molecular biology and bioinformatics tools.
We are looking for highly motivated and curious PhD students and PostDocs to join our team.
Required qualifications:
- MSc. or PhD. degree in microbial ecology, environmental genomics or related fields.
- Experience in DNA/RNA extraction techniques.
- Experience in bioinformatic/biostatistical pipelines using R or Python.
- Knowledge on the analysis and interpretation of microbial community genomics data.
The following additional qualifications will be advantageous:
- Background in bioaerosol research or related fields.
- Knowledge on molecular biology and microbiology techniques (i.e., genomic sequencing, qPCR, flow cytometry, cell culturing).
- The generation of NGS sequencing libraries.
Please contact:
Prof. Yinon Rudich
yinon.rudich@weizmann.ac.il
Department of Earth and Planetary Sciences
Weizmann Institute of Science
Department of Earth and Planetary Sciences
Postdoc position
Investigating the atmospheric chemistry of organic aerosol aging, physical properties, and potential health effects
More Information about Postdoc position
Aerosols participate in many environmental processes affecting the climate, human health and ecosystems. The qualified candidate will work on topics related to organic aerosol aging, physical properties, and potential health effects. Our research efforts focus on: a) understanding the origin, molecular composition, atmospheric transformations, and optical properties of light-absorbing organic aerosols (anthropogenic, biogenic, urban, and biomass burning SOA), and b) connecting aerosol composition, its changes, and the resulting health effects. Some relevant papers:
Required elements for research-based postdoc applications
Ph.D. in chemistry, chemical or environmental engineering, with a solid background in atmospheric and analytical chemistry and technology. Strong publication record. Prior hands-on experience with aerosol analytical and physical chemistry. Expertise with some of the advanced analytical techniques for aerosol technology, such as HR- ToF - AMS, oxidation flow reactors (PAM), aerosol characterization and handling (such as SMPS, APS, CPC, flow control). Experience with analytical chemistry is advantageous (FTIR, Raman and UV-Vis spectroscopy). Additional requirements include practice with handling and interpretation of multi-modal data sets; complex data analysis, computer programming skills, experience in working in a research team environment, good oral and written communication skills, interpersonal skills, initiative, creative and innovative thinking.
Lab website: https://www.weizmann.ac.il/EPS/Rudich/
Contact information: Prof. Yinon Rudich, Department of Earth and Planetary Sciences, Weizmann Institute, Rehovot 76100, Israel
e-mail: yinon.rudich@weizmann.ac.il
Tel: 972 8 934 4237
Department of Earth and Planetary Sciences
Postdoc position
Investigation the biological and toxicological effects of SOA from on-road car emissions funded by the EU
More Information about Postdoc position
Description and lab research areas:
Our lab studies the health impacts of air pollution, the number one environmental cause of the global disease burden. This newly funded EU project ( ASVOLEE, Effects on Air quality of Semi-VOLatile Engine Emissions) involves studying cytotoxicity imposed by exposure to SOA particles formed from on-road cars under real driving conditions.
The project will use cultured cell models, together with big data analysis such as toxicology, RNA sequencing, and metabolomics analyses. Recent laboratory experience and basic molecular biology and biochemistry skills are an advantage. Through this new EU project, we will offer a dynamic and international collaboration between the Weizmann Institute of Science and other key laboratories in Europe. The work involves active collaborations between the participating groups and taking active roles in joint experimental campaigns, data analyses, paper writing, and weekly joint seminars, among other activities.
The target of this PhD/Post Doc research focuses on investigating the mechanisms (biological and toxicological effects) induced by collected SOA in field campaigns with advanced exposure models. In vitro exposure will focus on optimizing exposure of human epithelial lung cells and other tissue (liver, fat) cultures and developing differentiated 3D cell cultures and disease-oriented tissue models.
Required elements for research-based postdoc applications: Recent laboratory experience and basic molecular biology and biochemistry skills are an advantage. PhD in Chemistry, Biology, Biochemistry, Atmospheric sciences, or related fields.
Please send applications to Prof. Yinon Rudich, Department of Earth and Planetary Sciences, Weizmann Institute, Rehovot 76100, Israel
e-mail: yinon.rudich@weizmann.ac.il, Tel: 972 8 934 4237
Lab website: https://www.weizmann.ac.il/EPS/Rudich/
Department of Physics of Complex Systems
Postdoc position
Our lab tries to bring molecules into the forefront of quantum technologies. We have open postdoc positions for leading and developing state-of-the-art quantum systems based on molecules.
For more information on our lab, visit: https://www.weizmann.ac.il/complex/meir/
Candidates should send their CV, list of publications, and a brief summary of their relevant scientific skills and achievements so far to ziv.meir@weizmann.ac.il
Department of Physics of Complex Systems
PhD position
Our lab tries to bring molecules into the forefront of quantum technologies. We have open PhD positions for quantum-physics enthusiastic with the eager to learn many experimental skills and build state-of-the-art quantum systems.
For more information on our lab, visit: https://www.weizmann.ac.il/complex/meir/
Department of Physics of Complex Systems
MSc position
Experimental MSc projects related to trapping and quantum control of atomic and molecular ions are available.
For more information on our lab, visit: https://www.weizmann.ac.il/complex/meir/
Department of Chemical and Biological Physics
Postdoc position
Studies of transition times in quantum and classical mechanics. We want to answer the question how long does it take to make a quantum transition. We are also interested in classical transition times for protein folding and the information they give. For further details see our recent publications and visit my website.
Department of Chemical and Biological Physics
Postdoc position
Positions are for development of lower bounds to energies which compete with the Ritz variational method in accuracy. They are for one year with option of renewal for another year. For more information visit my website: http://www.weizmann.ac.il/chemphys/pollak/positions
Department of Condensed Matter Physics
PhD position
Our lab investigates quantum phenomena which focus on the interplay between correlations and topology. This intriguing interplay allows to develop unique realizations of non-abelian quasi-particles (qps) which are neither Boson nor Fermion-like. Among the phases which host these qps are the well-known fractional quantum Hall effect, topological superconductivity, and the recently emerging field of moire-superlattcies (twistronics). We are developing experiments in these arrowheads to unravel this intriguing physics.
This line of research often utilizes quantum materials whose reduced dimensionality enhances quantum effects. We profit from the use of various van der Waals (vdW) materials (graphene, hBN, TMDs, etc.) as well as high-mobility two-dimensional GaAs electron gas, which are both grown in our department. Fabrication is performed in a state-of-the-art clean room facility, specially designed for vdW materials nanofabrication.
These devices will be measured with transport techniques including quantum Hall interferometry, Josephson interferometry, capacitance measurements, thermal transport, and shot noise measurements. These measurements require high magnetic fields and low electron temperatures. Our lab will be equipped with an 8mK wet dilution refrigerator with a 20T magnet, a 7mK dry dilution with a 3D vector magnet, as well as a variable temperature cryostat.
Interested candidates should contact: yuval.ronen@weizmann.ac.il
Department of Condensed Matter Physics
MSc position
Our lab investigates quantum phenomena which focus on the interplay between correlations and topology. This intriguing interplay allows to develop unique realizations of non-abelian quasi-particles (qps) which are neither Boson nor Fermion-like. Among the phases which host these qps are the well-known fractional quantum Hall effect, topological superconductivity, and the recently emerging field of moire-superlattcies (twistronics). We are developing experiments in these arrowheads to unravel this intriguing physics.
This line of research often utilizes quantum materials whose reduced dimensionality enhances quantum effects. We profit from the use of various van der Waals (vdW) materials (graphene, hBN, TMDs, etc.) as well as high-mobility two-dimensional GaAs electron gas, which are both grown in our department. Fabrication is performed in a state-of-the-art clean room facility, specially designed for vdW materials nanofabrication.
These devices will be measured with transport techniques including quantum Hall interferometry, Josephson interferometry, capacitance measurements, thermal transport, and shot noise measurements. These measurements require high magnetic fields and low electron temperatures.
Department of Condensed Matter Physics
Postdoc position
Our lab investigates quantum phenomena which focus on the interplay between correlations and topology. This intriguing interplay allows to develop unique realizations of non-abelian quasi-particles (qps) which are neither Boson nor Fermion-like. Among the phases which host these qps are the well-known fractional quantum Hall effect, topological superconductivity, and the recently emerging field of moire-superlattcies (twistronics). We are developing experiments in these arrowheads to unravel this intriguing physics.
This line of research often utilizes quantum materials whose reduced dimensionality enhances quantum effects. We profit from the use of various van der Waals (vdW) materials (graphene, hBN, TMDs, etc.) as well as high-mobility two-dimensional GaAs electron gas, which are both grown in our department. Fabrication is performed in a state-of-the-art clean room facility, specially designed for vdW materials nanofabrication.
These devices will be measured with transport techniques including quantum Hall interferometry, Josephson interferometry, capacitance measurements, thermal transport, and shot noise measurements. These measurements require high magnetic fields and low electron temperatures. Our lab will be equipped with an 8mK wet dilution refrigerator with a 20T magnet, a 7mK dry dilution with a 3D vector magnet, as well as a variable temperature cryostat.
Funding is available for three years. Advantage for prior experience with: vdW materials, fabrication techniques, transport measurements and cryogenic systems.
Interested candidates should send CV and list of publications to yuval.ronen@weizmann.ac.il
Department of Condensed Matter Physics
Postdoc position
Development of novel types of superconducting qubits and their use in quantum computation and simulation.
Department of Condensed Matter Physics
PhD position
Development of novel types of superconducting qubits and their use in quantum computation and simulation.
Department of Condensed Matter Physics
Postdoc position
Development of novel types of superconducting qubits and their use in quantum computation and simulation.
Department of Particle Physics and Astrophysics
MSc position
Phenomenology of particle physics
Department of Chemical and Biological Physics
Postdoc position
Postdoc in theoretical biological physics of cells - including mesoscale structure and dynamics of the cytoplasm and of the nucleus. Most projects are in collaboration with experimental partners. Strong background in statistical physics and soft matter physics is very useful. For examples of our research and publications see: https://www.weizmann.ac.il/chembiophys/SafranGroup/
More Information about Postdoc position
The Safran group focuses on theoretical studies of the structure, phase behavior and dynamics of biological cells and their relation to the soft matter, physical properties of membranes, macromolecules, and colloids, using the approaches of coarse-grained, statistical thermodynamics and dynamics. Through our interactions with experimental groups, the theory is applied to problems such as: cell volume determination, phase separation and chromatin organization at the nuclear scale, and spontaneous oscillations of cardiomyocytes.
Department of Particle Physics and Astrophysics
MSc position
M.Sc. in obsevational astrophysics, instrumentations, and methods.
More Information about MSc position
Working with the Large Array Survey Telescope (LAST). Including searching for fast transients and gravitational wave optical counterparts.
Department of Particle Physics and Astrophysics
PhD position
Using novel statistical and algorithmic tools to improve observational astrophysics (exoplanets, gravitational waves and pulsar astrophysics)
More Information about PhD position
The research in my group focuses on observational astrophysics, and our main tools are algorithms and statistics. We use these tools to improve observing capabilities in pulsar, FRB, exoplanet and gravitational wave astronomy.
Observational astrophysics is full with algorithmic and statistical questions that once solved, will dramatically improve our ability to observe the cosmos.
In my group, we combine tools of signal processing, statistical inference, dynamic programming, data structures, lattice algorithms, linear algebra algorithms, signal approximation, phase retrieval, optimization and Bayesian parameter estimation. Mastering these will be an indispensable tool for you wherever you go (academy / Hi-Tech)
It is very common that we invent new tools while trying to observe the cosmos. If you are looking for ways in which you can use your talent and creativity to observe the cosmos, this job post is for you.
Department of Particle Physics and Astrophysics
MSc position
Using novel statistical and algorithmic tools to improve observational astrophysics (exoplanets, gravitational waves and pulsar astrophysics)
More Information about MSc position
The research in my group focuses on observational astrophysics, and our main tools are algorithms and statistics. We use these tools to improve observing capabilities in pulsar, FRB, exoplanet and gravitational wave astronomy.
Observational astrophysics is full with algorithmic and statistical questions that once solved, will dramatically improve our ability to observe the cosmos.
In my group, we combine tools of signal processing, statistical inference, dynamic programming, data structures, lattice algorithms, linear algebra algorithms, signal approximation, phase retrieval, optimization and Bayesian parameter estimation. Mastering these will be an indispensable tool for you wherever you go (academy / Hi-Tech)
It is very common that we invent new tools while trying to observe the cosmos. If you are looking for ways in which you can use your talent and creativity to observe the cosmos, this job post is for you.
Department of Biomolecular Sciences
Postdoc position
The goal of our research is to understand how pancreatic beta cells perform their unique functions. Beta cells are the only cell in the body capable of significant production of insulin. They store insulin intracellularly, releasing it to the bloodstream in response to a variety of physiological stimuli including nutrients such as glucose and fatty acids, hormones and neurotransmitters.
More Information about Postdoc position
In our research, we focus on the following aspects of beta cell function:
- The transcriptional mechanisms underlying the normal embryonic development of beta cells and the functioning of mature beta cells
- Manipulating pancreatic cellular identity: molecular mechanisms controlling exocrine to endocrine cell reprogramming
- Dissecting the signaling mechanism that permit beta cells to respond to modulators of insulin secretion, in particular long chain and short chain fatty acids
See:
https://www.weizmann.ac.il/Biomolecular_Sciences/Walker/
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
The goal of our research is to understand how pancreatic beta cells perform their unique functions. Beta cells are the only cell in the body capable of significant production of insulin. They store insulin intracellularly, releasing it to the bloodstream in response to a variety of physiological stimuli including nutrients such as glucose and fatty acids, hormones and neurotransmitters.
More Information about MSc rotation
In our research, we focus on the following aspects of beta cell function:
- The transcriptional mechanisms underlying the normal embryonic development of beta cells and the functioning of mature beta cells
- Manipulating pancreatic cellular identity: molecular mechanisms controlling exocrine to endocrine cell reprogramming
- Dissecting the signaling mechanism that permit beta cells to respond to modulators of insulin secretion, in particular long chain and short chain fatty acids
See:
https://www.weizmann.ac.il/Biomolecular_Sciences/Walker/
Department of Biomolecular Sciences
Postdoc position
Molecular signaling in control of immune defense: regulation of programmed cell death and signaling for gene activation.
More Information about Postdoc position
Motivated and creative students with background in molecular biology are invited to join our studies of the mechanisms by which signaling by the TNF family contributes to immune defense, to chronic inflammatory and autoimmune diseases and to cancer, and our attempts to derive from this knowledge new ways of therapy. See our website and list of publications for the range of research subjects that we are exploring and for the range of experimental approaches that we are applying. (https://www.weizmann.ac.il/Biomolecular_Sciences/Wallach/home)
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Exploring the tumor-suppressor role of caspase-8, particularly in lung cancer.
More Information about MSc rotation
Caspase-8, a cysteine protease discovered in our laboratory, is the main proximal signaling enzyme in the activation of the extrinsic cell-death pathway by receptors of the TNF/NGF family. In certain cells it also participates in the regulation of cell growth, differentiation and survival. A number of different human tumors, including small cell lung carcinoma, neuroblastoma, hepatocellular carcinoma, and others, are frequently deficient of caspase-8. This deficiency occurs by several different mechanisms, indicating that it is not a consequence of the oncogenic transformation but is rather causal to it. Applying molecular approaches, cell-culture and animal models we explore the mechanisms accounting for the tumor suppressor role of caspase-8 and the functional consequences of its deletion in cancer cells.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Exploring the physiological function of signaling proteins that are activated by receptors of the TNF/NGF family.
More Information about MSc rotation
Transgenic and conditional-knockout mouse models are applied to gain better knowledge of the physiological and pathophysiological function of the following signaling proteins that were discovered in our laboratory: (a) Caspase-8, a cysteine protease that we have initially found to serve as the main proximal signaling protein in the initiation of death induction by the receptors (the extrinsic cell-death pathway), yet has more recently found also to serve various non-apoptotic roles. We are mainly interested in further exploring its function in the cross-talk between the epidermal and dermal layers of the skin, in the liver, and in the insulin-producing beta Langerhans cells. (b) NIK, a protein kinase (a MAP3K) that signals for activation of transcription factors of the NF kappa B family, specifically by receptors that, through activation of NF kappa B, control adaptive immunity and lymph-node generation. (c) CYLD, a deubiquitination enzyme that acts specifically to reverse K63-linked ubiquitination and thus serves to arrest initiation of several signaling cascades. (d) IREN, a member of the sorting-nexins family that mediates trafficking of signaling proteins activated by the receptors of the TNF/NGF family.
Department of Particle Physics and Astrophysics
PhD position
Theoretical high energy astrophysics research
Department of Particle Physics and Astrophysics
MSc position
Theoretical high energy astrophysics research
Department of Immunology and Regenerative Biology
Postdoc position
Emergence of resistance to anti-cancer drugs currently limits the application of relatively specific new drugs. We are interested in resolving the underlying mechanisms and, accordingly, offer novel combinations of drugs.
More Information about Postdoc position
Adaptive changes enable cancer cells to evade the apoptosis-inducing effects of anti-cancer drugs. We are interested in kinase inhibitors and monoclonal anti-tumor antibodies, which are often highly effective initially, but frequently loose activity due to adaptations and emergence of new mutations. Once the underlying mechanisms of drug resistance are resolved a new drug combination might be offered. The emergence of new mutations is driven by mutators that interfere with the normal function of the DNA replication fork, which is the focus of our studies. Similarly, we are interested in checkpoint inhibitors, such as PD-L1, the underlying oncogenic effects and ways to enhance responses to checkpoint inhibitors.
Department of Immunology and Regenerative Biology
MSc rotation
Available Rotations: 1st,2nd,3rd
Mechanisms of signal transduction by growth factors and their relevance to cancer therapy.
More Information about MSc rotation
The rotation will deal with the biochemical pathways underlying cell activation by growth factors. This relates to both cell proliferation and cell migration. We use RNA-sequencing, yeast 2-hybrid and immunological methods to resolve specific pathways. Currently we concentrate on mechanisms that inactivate cellular signals as part of negative feedback loops. These pathways are relevant to pharmacological attempts to block growth factor and tyrosine kinase signaling in human cancer. In this context, the work involves several novel drugs aimed at inhibiting lung, breast and colon cancer.
Department of Biomolecular Sciences
Postdoc position
We are looking for skilled and motivated postdocs to lead a project on gene amplification evolution in cancer. This project requires knowledge in experimental biology, microscopy and image analysis, and a variety of sequencing methodologies.
The candidate should have experience in cell culture work, molecular biology, and microscopy.
Expertise in bioinformatic analyses of DNA and RNA sequencing is a big advantage.
Our lab studies how catastrophic numerical and structural chromosome aberrations are formed in cancer. Such chromosome defects are found in the majority of human tumors and are strong drivers of cancer initiation, growth, metastasis, and therapy resistance. By understanding the underlying mechanisms of chromosome alterations, we aim to identify targetable vulnerabilities to be used for novel therapy design.
For more details, please contact Ofer: ofer.shoshani@weizmann.ac.il
Department of Plant and Environmental Sciences
Postdoc position
The Vardi lab is seeking highly skilled and motivated candidates with expertise in metabolomics to join a new and exciting project funded by the ERC in the field of chemical ecology, focusing on chemical communication during tripartite symbiotic and pathogenic interactions in the ocean. We aim to unravel the metabolic crosstalk between algae, viruses, and the associated microbiome, which has major ecological consequences on cell fate of algal blooms in the ocean.
Our laboratory employs state-of-the-art mass spectrometry, including high resolution LC-MS and GC-MS to investigate the metabolic dynamics of microbial interactions at sea.
The project will involve diverse analytical chemistry tools, such as:
- Targeted metabolomics and lipidomics
- Non-targeted metabolic profiling and fingerprinting
- de novo identification of novel metabolites
Department of Plant and Environmental Sciences
PhD position
The Vardi lab is seeking a highly motivated candidate to join a new and exciting project, funded by the ERC, to study the chemical language during host-pathogen interactions in the ocean. We aim to unravel the metabolic crosstalk between algae, viruses, and the associated microbiome, which has major ecological consequences on the oceanic carbon cycle. In light of climate change and increasing pathogenicity in marine ecosystems, these interactions may have a profound effect on ocean health.
The successful candidate will master analytical chemistry tools for targeted and untargeted metabolomics, as well as data analysis. They will employ state-of-the-art mass spectrometry, coupled to novel microbiology methods such as single cell analyses, both in model systems in the lab and natural communities in the ocean.
Department of Brain Sciences
PhD position
We study the genetic and cellular mechanisms through which sensory and emotional experiences alter information processing in neural circuits. Our research is highly interdisciplinary and combines genomic, molecular, histological, electrophysiological, in vivo imaging and behavioral techniques into an integrative Molecular Systems Neuroscience approach.
We seek to recruit Ph.D. students for the following projects:
- Molecular properties of functionally defined neurons in the cortex - the project combines in vivo GCaMP imaging & photo-labelling, advanced sequences methods and spatial transcriptomics.
- Genetic and cellular mechanisms through which schizophrenia-associated interneurons regulate the plasticity of cortical circuits.
- The genetic basis of representational stability in the cortex.
- Genes & transcriptional mechanisms in GABAergic interneurons that restrict plasticity in cortical circuits.
- Subcellular genetic mechanisms that integrate sensory and contextual/emotional information in neurons.
Department of Brain Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
We study the genetic and cellular mechanisms through which sensory and emotional experiences alter information processing in neural circuits. Our research is highly interdisciplinary and combines genomic, molecular, histological, electrophysiological, in vivo imaging and behavioral techniques into an integrative Molecular Systems Neuroscience approach.
We seek to recruit M.Sc. students for the following projects:
- Molecular properties of functionally defined neurons in the cortex - the project combines in vivo GCaMP imaging & photo-labelling, advanced sequences methods and spatial transcriptomics.
- Genetic and cellular mechanisms through which schizophrenia-associated interneurons regulate the plasticity of cortical circuits.
- The genetic basis of representational stability in the cortex.
- Genes & transcriptional mechanisms in GABAergic interneurons that restrict plasticity in cortical circuits.
- Subcellular genetic mechanisms that integrate sensory and contextual/emotional information in neurons.
Department of Brain Sciences
Postdoc position
We study the genetic and cellular mechanisms through which sensory and emotional experiences alter information processing in neural circuits. Our research is highly interdisciplinary and combines genomic, molecular, histological, electrophysiological, in vivo imaging and behavioral techniques into an integrative Molecular Systems Neuroscience approach.
We seek to recruit Ph.D. students for the following projects:
- Molecular properties of functionally defined neurons in the cortex - the project combines in vivo GCaMP imaging & photo-labelling, advanced sequences methods and spatial transcriptomics.
- Genetic and cellular mechanisms through which schizophrenia-associated interneurons regulate the plasticity of cortical circuits.
- The genetic basis of representational stability in the cortex.
- Genes & transcriptional mechanisms in GABAergic interneurons that restrict plasticity in cortical circuits.
- Subcellular genetic mechanisms that integrate sensory and contextual/emotional information in neurons.
Department of Physics of Complex Systems
MSc rotation
Available Rotations: 1st,2nd,3rd
Physics and Biology of natural microbial communities from an ancient site
Department of Physics of Complex Systems
PhD position
The physics of bacterial active matter
Department of Physics of Complex Systems
PhD position
Experimental study of the ecology of bacterial communities from a 700 million year old site
More Information about PhD position
Study active matter flocking in bacterial suspensions experimentally. The study involves in addition to real time experiments, image analysis using computer vision techniques and understanding the importance of metabolic interactions.
Study the stability/diversity interplay in bacterial consortia, and life under extreme conditions. The model system under study sheds light on astrobiology aspects as well as on sustainability under warming conditions
Department of Physics of Complex Systems
Postdoc position
Experimental study of the ecology of bacterial communities from a 700 million year old site
Department of Physics of Complex Systems
MSc position
Experimental study of the ecology of bacterial communities from a 700 million year old site
More Information about MSc position
Study active matter flocking in bacterial suspensions experimentally. The study involves in addition to real time experiments, image analysis using computer vision techniques and understanding the importance of metabolic interactions.
Department of Physics of Complex Systems
Postdoc position
Study of dynamics of viscoelastic straight channel flow, the role of inertial effect on its properties, and possible relation between elastic and elasto-inertial turbulence.
More Information about Postdoc position
Funding is available for three years. Contract is for one year, and will be renewed with good progress. The candidate should have a demonstrated potential for excellence in research. Advantage for background in experimental hydrodynamics, experience in particle image velocimetry (PIV), programming and computationally intensive data analysis. Knowledge and experience to characterize polymer solution is desirable. Interested candidates should send CV and list of publications to victor.steinberg@weizmann.ac.il
Department of Condensed Matter Physics
Postdoc position
Synthesis, fabrication, and study of van der Waals single crystals and heterostructures
More Information about Postdoc position
There are two classes of quantum materials that take the condensed matter community by storm, topological materials, and van der Waals heterostructures. In these systems specific electronic band structures, magnetic properties, and confinement of electrons to two dimensions lead to new states of matter with huge potential for future applications. Our group specializes in the synthesis and in-depth study of these materials, using the facilities of our recently established quantum materials laboratory. The project focuses on transition metal dichalcogenides, which are a rich playground for new types of topology protected surface states in bulk crystals, as well as important building blocks for van der Waals heterostructures when exfoliated down to few-layer or monolayer crystal sheets. The candidate will engage in synthesis and detailed experimental study of high purity single crystals, develop advanced synthesis methods, and closely collaborate with our ab-initio materials simulation group, as well as our nano-probe microscopy groups. Our infrastructure offers a wide range of facilities for chemical, structural and physical property analysis, and state-of-the-art tools for device fabrication. Synchrotron x-ray scattering at international facilities, high pressure experiments, and involvement in nano-probe microscopy experiments are further options, depending on background and inclination. The candidate should have extensive experience in materials synthesis and characterization, device fabrication, and the physics of topological materials or van der Waals heterostructures. The initial contract is for one year with possibility of extension up to three years pending on progress. Interested candidates should send a CV and list of publications to markus.huecker@weizmann.ac.il.
Department of Condensed Matter Physics
Postdoc position
Scanning probe microscopy of quantum and topological states of matter
More Information about Postdoc position
Study of quantum and topological states of matter using novel scanning probe microscopy tools. We have recently developed a nano-SQUID (Superconducting Quantum Interference Device) that resides on a very sharp tip and allows imaging of local magnetic fields with single electron spin sensitivity and of current flow patterns. This device provides also a unique tool for cryogenic thermal imaging with 1 ֲµK sensitivity and scanning gate microscopy allowing imaging electron scattering and dissipation mechanisms on the nanoscale. The project will focus on utilizing these novel techniques for microscopic investigation of topological and quantum states of matter including investigation of local topology, superconductivity, magnetism, strongly correlated electronic states, and dissipation in graphene, moiré superlattices, and van der Waals heterostructures.
Department of Condensed Matter Physics
MSc position
Scanning probe microscopy of quantum and topological states of matter
More Information about MSc position
Study of quantum and topological states of matter using novel scanning probe microscopy tools. We have recently developed a nano-SQUID (Superconducting Quantum Interference Device) that resides on a very sharp tip and allows imaging of local magnetic fields with single electron spin sensitivity and of current flow patterns. This device provides also a unique tool for cryogenic thermal imaging with 1 ֲµK sensitivity and scanning gate microscopy allowing imaging electron scattering and dissipation mechanisms on the nanoscale. The project will focus on utilizing these novel techniques for microscopic investigation of topological and quantum states of matter including investigation of local topology, superconductivity, magnetism, strongly correlated electronic states, and dissipation in graphene, moiré superlattices, and van der Waals heterostructures.
Department of Condensed Matter Physics
PhD position
Scanning probe microscopy of quantum and topological states of matter
More Information about PhD position
Study of quantum and topological states of matter using novel scanning probe microscopy tools. We have recently developed a nano-SQUID (Superconducting Quantum Interference Device) that resides on a very sharp tip and allows imaging of local magnetic fields with single electron spin sensitivity and of current flow patterns. This device provides also a unique tool for cryogenic thermal imaging with 1 ֲµK sensitivity and scanning gate microscopy allowing imaging electron scattering and dissipation mechanisms on the nanoscale. The project will focus on utilizing these novel techniques for microscopic investigation of topological and quantum states of matter including investigation of local topology, superconductivity, magnetism, strongly correlated electronic states, and dissipation in graphene, moiré superlattices, and van der Waals heterostructures.
Department of Immunology and Regenerative Biology
MSc rotation
Available Rotations: 1st,2nd,3rd
Functional Pre-Clinical Models for Normal and Leukemic Human Stem Cells: Molecular and cellular communication between stem cells and their bone marrow microenvironment. Circadian regulation of innate host immunity responses to bacterial infections by light and darkness cues as well as daily light and darkness onset regulation of blood and bone forming forming stem cells.
Department of Chemical and Structural Biology
PhD position
Talented and motivated student who wishes to study allostery and function in eukaryotic chaperonins and their connection to various diseases
Department of Chemical and Structural Biology
Postdoc position
Talented and motivated individual who wishes to study the mechanism of GroEL-assisted folding using molecular biology and biophysical approaches
Department of Molecular Cell Biology
Postdoc position
Immunotherapy has sparked new hope for oncology in recent years, due to its remarkable ability to induce durable response in patients with metastatic cancer. It is therefore essential to accurately delineate the interactions of cancer cells with the immune system. The project will use multiomic tools including whole exome sequencing , RNAseq, ribosome profiling, proteomic, HLA-peptidomics and systems biology to decipher the genetic, neo-antigenic and immune landscape in melanoma. Followup functional and immunological analysis of relevant genes and neoantigens will be conducted using novel mouse models
More Information about Postdoc position
Within the past decade, major advances have been made in the treatment of melanoma through the use of targeted therapy and immunotherapy, however responses are not universal and are not always durable. The project aims to further delineate the interactions of melanoma cells with the immune system to better understand molecular and immune mechanisms of therapeutic response and resistance. Our lab combines genomic tools, systems biology tools, advanced somatic cell knockout and knock-in techniques and various comprehensive mouse model approaches to study melanoma immune-genetics. Our studies link basic biology, computational biology and clinical studies. Trainees will learn sophisticated technologies such as whole exome sequencing, Riboseq, HLA-peptidomics, somatic cell knockouts and expression and proteomic analyses. Candidates who wish to join the group may contact me at: Yardena.samuels@weizmann.ac.il
Department of Molecular Cell Biology
Postdoc position
Immunotherapy has sparked new hope for oncology in recent years, due to its remarkable ability to induce durable response in patients with metastatic cancer. It is therefore essential to accurately delineate the interactions of cancer cells with the immune system. The project will use multiomic tools including whole exome sequencing , RNAseq, ribosome profiling, proteomic, HLA-peptidomics and systems biology to decipher the genetic, neo-antigenic and immune landscape in melanoma. Followup functional and immunological analysis of relevant genes and neoantigens will be conducted using novel mouse models
More Information about Postdoc position
Within the past decade, major advances have been made in the treatment of melanoma through the use of targeted therapy and immunotherapy, however responses are not universal and are not always durable. The project aims to further delineate the interactions of melanoma cells with the immune system to better understand molecular and immune mechanisms of therapeutic response and resistance. Our lab combines genomic tools, systems biology tools, advanced somatic cell knockout and knock-in techniques and various comprehensive mouse model approaches to study melanoma immune-genetics. Our studies link basic biology, computational biology and clinical studies. Trainees will learn sophisticated technologies such as whole exome sequencing, Riboseq, HLA-peptidomics, somatic cell knockouts and expression and proteomic analyses. Candidates who wish to join the group may contact me at: Yardena.samuels@weizmann.ac.il
Department of Molecular Cell Biology
PhD position
Immunotherapy has sparked new hope for oncology in recent years, due to its remarkable ability to induce durable response in patients with metastatic cancer. It is therefore essential to accurately delineate the interactions of cancer cells with the immune system. The project will use multiomic tools including whole exome sequencing , RNAseq, ribosome profiling, proteomic, HLA-peptidomics and systems biology to decipher the genetic, neo-antigenic and immune landscape in melanoma. Followup functional and immunological analysis of relevant genes and neoantigens will be conducted using novel mouse models
More Information about PhD position
Within the past decade, major advances have been made in the treatment of melanoma through the use of targeted therapy and immunotherapy, however responses are not universal and are not always durable. The project aims to further delineate the interactions of melanoma cells with the immune system to better understand molecular and immune mechanisms of therapeutic response and resistance. Our lab combines genomic tools, systems biology tools, advanced somatic cell knockout and knock-in techniques and various comprehensive mouse model approaches to study melanoma immune-genetics. Our studies link basic biology, computational biology and clinical studies. Trainees will learn sophisticated technologies such as whole exome sequencing, Riboseq, HLA-peptidomics, somatic cell knockouts and expression and proteomic analyses. Candidates who wish to join the group may contact me at: Yardena.samuels@weizmann.ac.il
Department of Molecular Cell Biology
MSc position
Immunotherapy has sparked new hope for oncology in recent years, due to its remarkable ability to induce durable response in patients with metastatic cancer. It is therefore essential to accurately delineate the interactions of cancer cells with the immune system. The project will use multiomic tools including whole exome sequencing , RNAseq, ribosome profiling, proteomic, HLA-peptidomics and systems biology to decipher the genetic, neo-antigenic and immune landscape in melanoma. Followup functional and immunological analysis of relevant genes and neoantigens will be conducted using novel mouse models
More Information about MSc position
Within the past decade, major advances have been made in the treatment of melanoma through the use of targeted therapy and immunotherapy, however responses are not universal and are not always durable. The project aims to further delineate the interactions of melanoma cells with the immune system to better understand molecular and immune mechanisms of therapeutic response and resistance. Our lab combines genomic tools, systems biology tools, advanced somatic cell knockout and knock-in techniques and various comprehensive mouse model approaches to study melanoma immune-genetics. Our studies link basic biology, computational biology and clinical studies. Trainees will learn sophisticated technologies such as whole exome sequencing, Riboseq, HLA-peptidomics, somatic cell knockouts and expression and proteomic analyses. Candidates who wish to join the group may contact me at: Yardena.samuels@weizmann.ac.il
Department of Molecular Cell Biology
PhD position
Immunotherapy has sparked new hope for oncology in recent years, due to its remarkable ability to induce durable response in patients with metastatic cancer. It is therefore essential to accurately delineate the interactions of cancer cells with the immune system. The project will use multiomic tools including whole exome sequencing , RNAseq, ribosome profiling, proteomic, HLA-peptidomics and systems biology to decipher the genetic, neo-antigenic and immune landscape in melanoma. Followup functional and immunological analysis of relevant genes and neoantigens will be conducted using novel mouse models
More Information about PhD position
Within the past decade, major advances have been made in the treatment of melanoma through the use of targeted therapy and immunotherapy, however responses are not universal and are not always durable. The project aims to further delineate the interactions of melanoma cells with the immune system to better understand molecular and immune mechanisms of therapeutic response and resistance. Our lab combines genomic tools, systems biology tools, advanced somatic cell knockout and knock-in techniques and various comprehensive mouse model approaches to study melanoma immune-genetics. Our studies link basic biology, computational biology and clinical studies. Trainees will learn sophisticated technologies such as whole exome sequencing, Riboseq, HLA-peptidomics, somatic cell knockouts and expression and proteomic analyses. Candidates who wish to join the group may contact me at: Yardena.samuels@weizmann.ac.il
Department of Molecular Cell Biology
PhD position
Immunotherapy has sparked new hope for oncology in recent years, due to its remarkable ability to induce durable response in patients with metastatic cancer. It is therefore essential to accurately delineate the interactions of cancer cells with the immune system. The project will use multiomic tools including whole exome sequencing , RNAseq, ribosome profiling, proteomic, HLA-peptidomics and systems biology to decipher the genetic, neo-antigenic and immune landscape in melanoma. Followup functional and immunological analysis of relevant genes and neoantigens will be conducted using novel mouse models
More Information about PhD position
Within the past decade, major advances have been made in the treatment of melanoma through the use of targeted therapy and immunotherapy, however responses are not universal and are not always durable. The project aims to further delineate the interactions of melanoma cells with the immune system to better understand molecular and immune mechanisms of therapeutic response and resistance. Our lab combines genomic tools, systems biology tools, advanced somatic cell knockout and knock-in techniques and various comprehensive mouse model approaches to study melanoma immune-genetics. Our studies link basic biology, computational biology and clinical studies. Trainees will learn sophisticated technologies such as whole exome sequencing, Riboseq, HLA-peptidomics, somatic cell knockouts and expression and proteomic analyses. Candidates who wish to join the group may contact me at: Yardena.samuels@weizmann.ac.il
Department of Molecular Cell Biology
Postdoc position
Dissecting metabolic changes that accompany carcinogenesis at the tumor, microenvironment and host levels for improving cancer diagnosis and therapy.
More Information about Postdoc position
Starting from a clinically relevant question we follow the metabolic changes that occur along cancer disease course. Identifying such changes enables us to optimize early cancer diagnosis and to intervene therapeutically.
Department of Molecular Cell Biology
PhD position
Dissecting metabolic changes that accompany carcinogenesis at the tumor, microenvironment and host levels for improving cancer diagnosis and therapy.
Department of Molecular Cell Biology
MSc rotation
Available Rotations: 1st,2nd,3rd
Identifying metabolic changes during carcinogenesis at the tumor, environment and host levels for imporoving cancer diagnosis and therapy.
Department of Computer Science and Applied Mathematics
MSc position
The Signal Acquisition, Modeling,Processing and Learning (SAMPL) lab headed by Prof. Yonina Eldar at the Weizmann Institute of Science is recruiting PhD, MSc and post-doctoral students for cutting-edge research applying machine learning and deep networks to clinical problems.
Department of Computer Science and Applied Mathematics
MSc rotation
Available Rotations: 1st,2nd,3rd
Rotation in using machine learning for drug discovery. Involves advanced AI over graphs describing drug interactions.
Department of Computer Science and Applied Mathematics
MSc rotation
Available Rotations: 1st,2nd,3rd
Rotation in using machine learning for inverse radar to measure inside the human skull. Involves advanced AI with radar and clinical applications.
Department of Computer Science and Applied Mathematics
MSc rotation
Available Rotations: 1st,2nd,3rd
Rotation in the use of radar for vital sign monitoring: combining signal processing with biological properties.
Department of Computer Science and Applied Mathematics
MSc rotation
Available Rotations: 1st,2nd,3rd
Rotation in new ideas of samlping thoery and their applications to certain communication problems.
Department of Computer Science and Applied Mathematics
PhD position
Recruiting PhD, MSc and post-doctoral students for cutting-edge research applying signal processing and machine learning for communication and radar systems.
Department of Computer Science and Applied Mathematics
MSc position
Recruiting PhD, MSc and post-doctoral students for cutting-edge research applying signal processing and machine learning for communication and radar systems.
Department of Particle Physics and Astrophysics
MSc position
Particle physics data analysis / Particle physics detectors
A standalone project that will be part of the real work at the lab.
Department of Particle Physics and Astrophysics
PhD position
Data analysis from the ATLAS experiment.
Heavy Ion Physics is about exploring what the Strong Force Interaction is. Our World is not only confined to two- and three-quark particles. Imagine a system built of as many quarks as you want. Do we know enough to tell how such a system would behave? Would it be a quark-gluon plasma, a hadronic gas, or liquid? Does QCD do a good job predicting its properties, or...
You can help to find answers to these and many other questions. About one month in a year, the LHC collides ions of heavy elements. Each of these collisions is a mini-universe that sends hundreds of times more particles into ATLAS detector than a proton-proton interaction. You can be a part of a team to dive into this sea of quarks and gluons and find an answer to one of many questions.
Heavy-ion data from the ATLAS experiment is an excellent opportunity for students seeking an academic carrier to do research and get fantastic visibility in the physics community. But if you want to learn the most sophisticated data analysis, create your own algorithms, and get into the world of finance, data mining or high-tech, it's a place for you too.
Department of Physics of Complex Systems
PhD position
Experimental and theoretical studies of neutral atom quantum simulators
More Information about PhD position
In collaboration with Ofer Firstenberg recently started a new joint project on efficient coupling of neutral-atom tweezer arrays to light. On the theoretical side we are collaborating with Efi Shahmoon. We plan to extend Efi’s original ideas for strong coupling in atomic arrays in sub-wavelength optical lattices (recently verified experimentally by Immanuel Bloch) to the emerging and promising field of quantum simulators with Rydberg atoms in tweezer arrays, where the spacing between the atoms is larger than the wavelength. The challenge to achieved strong coupling to light in such large-spacing arrays emerges from the existence of many diffraction orders that cannot be controlled.
Our proposed scheme to overcome this challenge is based on two supplementary efforts: first we will reduce the spacing between neighboring atoms in the array to <1.5 microns, by suppressing the mutual interferences that limit this distance to >3 microns in most state of the art demonstrations. Such spacing reduction will reduce the non-vanishing diffraction orders from the periodic array from many tens to only few. Next we will incorporate the tweezer array inside a medium finesse optical cavity that will enhance the zero diffraction order as compared to the others so as to ensure strong coupling to it.
We plan to achieve strong coupling to light, show efficient transfer of coherence and quantum states from the array onto a single radiation mode and then use it to demonstrate and study novel schemes for quantum simulators within the atomic tweezer array as well as quantum coupling between tweezer arrays for “scalable” quantum computer based on Rydberg induced gates.
Department of Physics of Complex Systems
Postdoc position
Experimental and theoretical studies of ultra-cold quantum degenerate Bose and Fermi gas
More Information about Postdoc position
In collaboration with Roee Ozeri we form Bose Einstein condensates of rubidium 87 atoms, quantum degenerated fermionic gas of potassium 40 atoms, and their mixtures using laser cooling and evaporative cooling in magnetic and far-detuned optical traps and study their properties. Such dilute quantum gases offer full control of external and internal degrees of freedom and variety of unique interrogation tools that enable precise studies of many body quantum systems.
By using magnetic Feshbach resonances we tune the system from weakly interacting where the it can be simply described by a macroscopic wave function to the strongly interacting where highly correlated many body states can be generated and studied. We study and characterize the coherence, dynamics and elementary excitations of these dilute quantum gases using laser and microwave probes and study new type of an opto-mechanical force when they are illuminated with far-detuned uniform laser beam.
Department of Physics of Complex Systems
PhD position
Experimental and theoretical studies of ultra-cold quantum degenerate Bose and Fermi gas
More Information about PhD position
In collaboration with Roee Ozeri we form Bose Einstein condensates of rubidium 87 atoms, quantum degenerated fermionic gas of potassium 40 atoms, and their mixtures using laser cooling and evaporative cooling in magnetic and far-detuned optical traps and study their properties. Such dilute quantum gases offer full control of external and internal degrees of freedom and variety of unique interrogation tools that enable precise studies of many body quantum systems.
By using magnetic Feshbach resonances we tune the system from weakly interacting where the it can be simply described by a macroscopic wave function to the strongly interacting where highly correlated many body states can be generated and studied. We study and characterize the coherence, dynamics and elementary excitations of these dilute quantum gases using laser and microwave probes and study new type of an opto-mechanical force when they are illuminated with far-detuned uniform laser beam.
Department of Physics of Complex Systems
Postdoc position
Experimental and theoretical studies of laser spin simulators and solvers
More Information about Postdoc position
We investigate phase locking of large arrays of coupled lasers in a modified degenerate cavity. We show that the minimal loss lasing solution is mapped to the ground state of an XY spin Hamiltonian with the same coupling matrix provided the intensity of all the lasers is uniform. We study the probability to obtain this ground state for various coupling schemes, system parameters and topological constrains. We demonstrate the effect of crowd synchrony with a sharp transition into an ordered state above a critical number of coupled lasers. Finally, we present recent results demonstrating the ability of our system to solve related problems such as phase retrieval, imaging through scattering medium and more.
Department of Physics of Complex Systems
PhD position
Experimental and theoretical studies of laser spin simulators and solvers
More Information about PhD position
We investigate phase locking of large arrays of coupled lasers in a modified degenerate cavity. We show that the minimal loss lasing solution is mapped to the ground state of an XY spin Hamiltonian with the same coupling matrix provided the intensity of all the lasers is uniform. We study the probability to obtain this ground state for various coupling schemes, system parameters and topological constrains. We demonstrate the effect of crowd synchrony with a sharp transition into an ordered state above a critical number of coupled lasers. Finally, we present recent results demonstrating the ability of our system to solve related problems such as phase retrieval, imaging through scattering medium and more.
Department of Physics of Complex Systems
MSc position
Experimental and theoretical studies of neutral atom quantum simulators
More Information about MSc position
In collaboration with Ofer Firstenberg recently started a new joint project on efficient coupling of neutral-atom tweezer arrays to light. On the theoretical side we are collaborating with Efi Shahmoon. We plan to extend Efi’s original ideas for strong coupling in atomic arrays in sub-wavelength optical lattices (recently verified experimentally by Immanuel Bloch) to the emerging and promising field of quantum simulators with Rydberg atoms in tweezer arrays, where the spacing between the atoms is larger than the wavelength. The challenge to achieved strong coupling to light in such large-spacing arrays emerges from the existence of many diffraction orders that cannot be controlled.
Our proposed scheme to overcome this challenge is based on two supplementary efforts: first we will reduce the spacing between neighboring atoms in the array to <1.5 microns, by suppressing the mutual interferences that limit this distance to >3 microns in most state of the art demonstrations. Such spacing reduction will reduce the non-vanishing diffraction orders from the periodic array from many tens to only few. Next we will incorporate the tweezer array inside a medium finesse optical cavity that will enhance the zero diffraction order as compared to the others so as to ensure strong coupling to it.
We plan to achieve strong coupling to light, show efficient transfer of coherence and quantum states from the array onto a single radiation mode and then use it to demonstrate and study novel schemes for quantum simulators within the atomic tweezer array as well as quantum coupling between tweezer arrays for “scalable” quantum computer based on Rydberg induced gates.
Department of Physics of Complex Systems
MSc position
Experimental and theoretical studies of ultra-cold quantum degenerate Bose and Fermi gas
More Information about MSc position
In collaboration with Roee Ozeri we form Bose Einstein condensates of rubidium 87 atoms, quantum degenerated fermionic gas of potassium 40 atoms, and their mixtures using laser cooling and evaporative cooling in magnetic and far-detuned optical traps and study their properties. Such dilute quantum gases offer full control of external and internal degrees of freedom and variety of unique interrogation tools that enable precise studies of many body quantum systems.
By using magnetic Feshbach resonances we tune the system from weakly interacting where the it can be simply described by a macroscopic wave function to the strongly interacting where highly correlated many body states can be generated and studied. We study and characterize the coherence, dynamics and elementary excitations of these dilute quantum gases using laser and microwave probes and study new type of an opto-mechanical force when they are illuminated with far-detuned uniform laser beam.
Department of Physics of Complex Systems
MSc position
Experimental and theoretical studies of laser spin simulators and solvers
More Information about MSc position
We investigate phase locking of large arrays of coupled lasers in a modified degenerate cavity. We show that the minimal loss lasing solution is mapped to the ground state of an XY spin Hamiltonian with the same coupling matrix provided the intensity of all the lasers is uniform. We study the probability to obtain this ground state for various coupling schemes, system parameters and topological constrains. We demonstrate the effect of crowd synchrony with a sharp transition into an ordered state above a critical number of coupled lasers. Finally, we present recent results demonstrating the ability of our system to solve related problems such as phase retrieval, imaging through scattering medium and more.
Department of Physics of Complex Systems
Postdoc position
Experimental and theoretical studies of neutral atom quantum simulators
More Information about Postdoc position
In collaboration with Ofer Firstenberg recently started a new joint project on efficient coupling of neutral-atom tweezer arrays to light. On the theoretical side we are collaborating with Efi Shahmoon. We plan to extend Efi’s original ideas for strong coupling in atomic arrays in sub-wavelength optical lattices (recently verified experimentally by Immanuel Bloch) to the emerging and promising field of quantum simulators with Rydberg atoms in tweezer arrays, where the spacing between the atoms is larger than the wavelength. The challenge to achieved strong coupling to light in such large-spacing arrays emerges from the existence of many diffraction orders that cannot be controlled.
Our proposed scheme to overcome this challenge is based on two supplementary efforts: first we will reduce the spacing between neighboring atoms in the array to <1.5 microns, by suppressing the mutual interferences that limit this distance to >3 microns in most state of the art demonstrations. Such spacing reduction will reduce the non-vanishing diffraction orders from the periodic array from many tens to only few. Next we will incorporate the tweezer array inside a medium finesse optical cavity that will enhance the zero diffraction order as compared to the others so as to ensure strong coupling to it.
We plan to achieve strong coupling to light, show efficient transfer of coherence and quantum states from the array onto a single radiation mode and then use it to demonstrate and study novel schemes for quantum simulators within the atomic tweezer array as well as quantum coupling between tweezer arrays for “scalable” quantum computer based on Rydberg induced gates.
Department of Chemical and Biological Physics
Postdoc position
Employ state-of-the-art single-molecule fluorescence methods to study the dynamics of large protein machines. Decipher the role of microsecond-time-scale motions on the function of these machines.
Experience in single-molecule spectroscopy is a plus, but candidates with experience in any branch of spectroscopy or biophysics are welcome.
Department of Chemical and Biological Physics
PhD position
Employ state-of-the-art single-molecule fluorescence methods to study the dynamics of large protein machines. Decipher the role of microsecond-time-scale motions on the function of these machines.
Acquire a broad set of skills, from protein chemistry to single-molecule spectroscopy and statistical methodology for data analysis.
Department of Chemical and Biological Physics
MSc rotation
Available Rotations: 2nd,3rd
Nanoplasmonics- interaction of light with small metallic particles and molecules
Department of Chemical and Biological Physics
MSc rotation
Available Rotations: 2nd,3rd
Single-molecule fluorescence experiments to study protein folding and dynamics.
Department of Biomolecular Sciences
PhD position
We study the mitochondria, and are especially passionate about their most ancient and conserved pathway- iron-sulfur cluster biosynthesis
More Information about PhD position
Mitochondria are essential for the function of the eukaryotic cell- why?
Over the past two decades it has become apparent that a core and ubiquitous function of mitochondria is iron-sulfur (Fe-S) cluster biosynthesis. These ancient co-factors, which are produced in the mitochondria, are vital for proteins that take part in DNA replication, translation, metabolism and cellular respiration. In light of these essential tasks, it's not surprising that problems in Fe-S cluster synthesis are linked to human diseases, including the most common mitochondrial disease- Friedreich's ataxia. Yet surprisingly little is known about this pathway, and how it is regulated by the cell is even more mysterious.
Our lab couples cutting edge genetic and high content tools with cell biology and biochemistry approaches to shed new light on this essential pathway and how it's wired into the human cell.
To learn more, visit: https://www.astlabweizmann.com/
To hear Tslil talking about our science, visit: https://www.youtube.com/watch?v=H4u6p8WmzvE&t=17s
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 3rd
We study the mitochondria in human health and disease, and are especially passionate about their most ancient and conserved pathway- iron-sulfur cluster biosynthesis.
More Information about MSc rotation
Mitochondria are essential for the function of the eukaryotic cell- why?
Over the past two decades it has become apparent that a core and ubiquitous function of mitochondria is iron-sulfur (Fe-S) cluster biosynthesis. These ancient co-factors, which are produced in the mitochondria, are vital for proteins that take part in DNA replication, translation, metabolism and cellular respiration. In light of these essential tasks, it's not surprising that problems in Fe-S cluster synthesis are linked to human diseases, including the most common mitochondrial disease- Friedreich's ataxia. Yet surprisingly little is known about this pathway, and how it is regulated by the cell is even more mysterious.
Our lab couples cutting edge genetic and high content tools with cell biology and biochemistry approaches to shed new light on this essential pathway and how it's wired into the human cell.
To learn more, visit: https://www.astlabweizmann.com/
To hear Tslil talking about our science, visit: https://www.youtube.com/watch?v=H4u6p8WmzvE&t=17s
Department of Biomolecular Sciences
MSc position
Understanding how the transcription and translation processes control the cellular response to extra-cellular stimuli
More Information about MSc position
Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to environmental stimuli; (ii) to reveal the connections between the transcription and translation processes and (iii) to develop tools to manipulate these processes for the potential treatment of cancer, chronic inflammation and neurodegenerative diseases.
Department of Biomolecular Sciences
PhD position
Understanding how the transcription and translation processes control the cellular response to extra-cellular stimuli
More Information about PhD position
Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to environmental stimuli; (ii) to reveal the connections between the transcription and translation processes and (iii) to develop tools to manipulate these processes for the potential treatment of cancer, chronic inflammation and neurodegenerative diseases.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Understanding how the transcription and translation processes control the cellular response to extra-cellular stimuli
More Information about MSc rotation
Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to enviromental stimuli; (ii) to reveal the connections between the transcription and translation processes and (iii) to develop tools to manipulate these processes for potential treatment of cancer, chronic inflammation and neurodegenrative diseases.
Department of Biomolecular Sciences
Postdoc position
Understanding how the transcription and translation processes control the cellular response to extra-cellular stimuli
More Information about Postdoc position
Regulation of gene expression at the transcriptional and translational levels is fundamental to all biological activities and is frequently altered in disease states. Our broad research interests are (i) to elucidate how the transcription and translation processes control the cellular response to enviromental stimuli; (ii) to reveal the connections between the transcription and translation processes and (iii) to develop tools to manipulate these processes for the potential treatment of cancer, chronic inflammation and neurodegenrative diseases.
Department of Molecular Cell Biology
Postdoc position
Combination therapies for TNBC
More Information about Postdoc position
Triple negative breast cancer (TNBC) is a highly aggressive disease that affects young women and currently has no effective treatment. The goal of our studies is to identify new therapeutic strategies for this particular subtype of breast cancer. Synthetic lethality is a powerful approach to selectively eliminate vulnerable cancer cells, and thus can be exploited for cancer therapy. Many studies including our own indicate that synthetic lethality screens could be a promising approach to identify novel drug targets for TNBC. A postdoctoral position is available to establish a genome-wide synthetic lethal screen to identify potent combination therapies for TNBC subtypes.
Department of Molecular Cell Biology
Postdoc position
More Information about Postdoc position
Ferroptosis is a newly discovered cell death pathway driven by iron-dependent lipid peroxidation. We recently discovered new inducers of ferroptosis, and specific metabolic states that increase vulnerability to ferroptosis, and thus can be used for cancer therapy. We have multidisciplinary projects related to ferroptosis in TNBC, and we are currently looking for two talented and enthusiastic postdocs to join us.
Department of Molecular Genetics
MSc rotation
Available Rotations: 1st,2nd,3rd
The Laufman lab studies the ways human RNA viruses interact with their host cells and transform them into viral manufactories using state-of-the-art microscopy, molecular and cell biology, genetic and biochemistry approaches. We tackle questions at the forefront of the exciting field of virology, and offer an exceptional scientific environment to develop your skills and career as a researcher. We are looking for talented and highly motivated rotation students to join our team.
Department of Molecular Genetics
PhD position
The Laufman lab studies the ways human RNA viruses interact with their host cells and transform them into viral manufactories using state-of-the-art microscopy, molecular and cell biology, genetic and biochemistry approaches. We tackle questions at the forefront of the exciting field of virology. We are looking for talented and highly motivated PhD students to join us. If you possess a strong background in molecular biology and the passion to execute a groundbreaking research - your place is with us! We offer an exceptional scientific environment to develop into a mature top-class researcher. Our team members enjoy a pleasant and supportive research environment at the heart of the vibrant campus of the Weizmann Institute of Science.
Department of Molecular Genetics
Postdoc position
The Laufman lab studies the ways human RNA viruses interact with their host cells and transform them into viral manufactories using cutting-edge microscopy, molecular and cell biology, genetic and biochemistry approaches. We tackle questions at the forefront of the exciting field of virology. We are looking for talented and highly motivated postdocs to join our team. If you possess a strong background in molecular biology and the passion to execute a groundbreaking research – your place is with us! We are located in the heart of the vibrant campus of the Weizmann Institute of Science, with state-of-the-art research facilities and a variety of supportive services such as recreation center, infants’ daycare, lawns and sport fields and much more.
Department of Systems Immunology
PhD position
a brand-new lab at the Systems Immunology department looking to recruit the first generation of lab members!
Our focus is on understanding the cellular networks that control both inflammatory and peaceful immune responses. We develop cutting-edge technologies and combine them with classical immunology techniques, along with mouse genetics, to investigate communication between T cells and various types of antigen-presenting cells.
More Information about PhD position
As living creatures, we are continually interacting with our surroundings and our immune system is required to distinguish non-harmful entities from dangerous intruders and react accordingly. CD4 T cells are activated by different antigen presenting cell (APC) and acquire alternative cell fates to mediate distinct immune responses. Antigen presentation also allows activated T cells to act and instruct specific antigen presenters. Thus, antigen presentation is the beating heart of adaptive immunity, allowing ongoing cross-talk between multiple cell types to achieve immunity and tissue adaptation.
?Which APCs instruct T cells? Which APCs are instructed by T cells?
?While tools to allow monitoring of specific T cell responses were invented 20 years ago and revolutionized our understanding of adaptive immunity, identifying which APC presents specific peptides, at the single cell level is still out of reach.
We will combine an engineering approach and biochemistry with single-cell RNA sequencing technologies, to develop a method for detecting specific antigen presenters. We believe that this technology along with classical immunology, will enable us to address fundamental questions in the field of antigen presentation.
Department of Systems Immunology
Postdoc position
a brand-new lab at the Systems Immunology department looking to recruit the first generation of lab members!
Our focus is on understanding the cellular networks that control both inflammatory and peaceful immune responses. We develop cutting-edge technologies and combine them with classical immunology techniques, along with mouse genetics, to investigate communication between T cells and various types of antigen-presenting cells.
More Information about Postdoc position
As living creatures, we are continually interacting with our surroundings and our immune system is required to distinguish non-harmful entities from dangerous intruders and react accordingly. CD4 T cells are activated by different antigen presenting cell (APC) and acquire alternative cell fates to mediate distinct immune responses. Antigen presentation also allows activated T cells to act and instruct specific antigen presenters. Thus, antigen presentation is the beating heart of adaptive immunity, allowing ongoing cross-talk between multiple cell types to achieve immunity and tissue adaptation.
?Which APCs instruct T cells? Which APCs are instructed by T cells?
?While tools to allow monitoring of specific T cell responses were invented 20 years ago and revolutionized our understanding of adaptive immunity, identifying which APC presents specific peptides, at the single cell level is still out of reach.
We will combine an engineering approach and biochemistry with single-cell RNA sequencing technologies, to develop a method for detecting specific antigen presenters. We believe that this technology along with classical immunology, will enable us to address fundamental questions in the field of antigen presentation.
Department of Systems Immunology
MSc rotation
Available Rotations: 3rd
a brand-new lab at the Systems Immunology department looking to recruit the first generation of lab members!
Our focus is on understanding the cellular networks that control both inflammatory and peaceful immune responses. We develop cutting-edge technologies and combine them with classical immunology techniques, along with mouse genetics, to investigate communication between T cells and various types of antigen-presenting cells.
More Information about MSc rotation
As living creatures, we are continually interacting with our surroundings and our immune system is required to distinguish non-harmful entities from dangerous intruders and react accordingly. CD4 T cells are activated by different antigen presenting cell (APC) and acquire alternative cell fates to mediate distinct immune responses. Antigen presentation also allows activated T cells to act and instruct specific antigen presenters. Thus, antigen presentation is the beating heart of adaptive immunity, allowing ongoing cross-talk between multiple cell types to achieve immunity and tissue adaptation.
?Which APCs instruct T cells? Which APCs are instructed by T cells?
?While tools to allow monitoring of specific T cell responses were invented 20 years ago and revolutionized our understanding of adaptive immunity, identifying which APC presents specific peptides, at the single cell level is still out of reach.
We will combine an engineering approach and biochemistry with single-cell RNA sequencing technologies, to develop a method for detecting specific antigen presenters. We believe that this technology along with classical immunology, will enable us to address fundamental questions in the field of antigen presentation.
Department of Chemical and Structural Biology
PhD position
NMR studies of transient chaperone-substrate interactions
More Information about PhD position
Almost all proteins depend on a well-defined three-dimensional structure to obtain their functionality. In order to prevent misfolding, aggregation, and the generation of toxic species, the process of protein folding in the cell is often guided by molecular chaperones. These complex protein networks either interact with substrate polypeptides to help them fold; unfold misfolded species; dissolve aggregates; or deliver substrates to proteolysis. Very little structural information, however, is available regarding how chaperones bind their substrates or the manner in which they protect proteins from misfolding and aggregation.
This lack of information arises from the highly dynamic nature of chaperone-substrate complexes – a trait that prevents their characterization by traditional structural techniques, but fortunately for us, makes them great targets for NMR spectroscopy.
In this project we will use solution-state NMR to probe the molecular interactions between hundreds-of-kilodalton large chaperone complexes and “client” proteins, as well as the structural and dynamic features of these complexes
Department of Chemical and Structural Biology
MSc rotation
Available Rotations: 1st,2nd,3rd
Elucidating the role of molecular chaperones in cancer
More Information about MSc rotation
The Hsp70 chaperone is of prime importance to cancer biology; supporting proliferative growth and stress survival, blocking apoptosis, and fighting protein aggregation caused by aneuploidy or mutation. One central cancer-related substrate of the Hsp70 system is the p53 tumor suppressor protein, in both wild-type and mutant forms, which interacts with the Hsp70 system for (re)folding, stabilization, and degradation. The molecular basis of these interactions and pathway triaging, however, are unknown. This project therefore aims to characterize the roles these molecular chaperones play in cancer pathology.
Department of Immunology and Regenerative Biology
Postdoc position
Genetically encoded metal transporters in pregnancy
More Information about Postdoc position
Development of novel genetically encoded metal binding proteins for targeted imaging and therapy.
This study will extend our research on ferritin as a reporter gene for MRI:
https://www.weizmann.ac.il/dept/irb/neeman/research-activities/protocols-reporter-genes-and-probes-molecular-imaging
Department of Immunology and Regenerative Biology
Postdoc position
The objective of this study is to better understand the state and severity of infection during pregnancy and its effect on fetal development and neonatal outcome.
Department of Immunology and Regenerative Biology
MSc position
MRI pathology of placenta and pregnancy complications
More Information about MSc position
The objective of this study is to better understand and provide early markers for pregnancy complications, the state and severity of infection during pregnancy and their effect on fetal development and neonatal outcome.
Department of Immunology and Regenerative Biology
MSc rotation
Available Rotations: 1st,2nd,3rd
MRI and optical imaging of placenta function and fetal development.
More Information about MSc rotation
Analysis of placenta function, understanding placenta transport mechanisms and analysis of placenta pathologies in human pregnancy complications and in transgenic mouse models.
Department of Biomolecular Sciences
Postdoc position
OPEN POSTDOC positions
We are seeking highly motivated, independent, committed and curious researchers to join our team as Post-Doc. The projects center on the cellular biology of the malaria parasite, immune response, parasite-host interaction and the field of cell-cell communication.
More Information about Postdoc position
Applicants with a strong research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms (including image analysis) or advanced protein chemistry is advantageous. This is a full-time position available from October 2023 for a period of two years with a possibility of a further extension subject to funding availability. Candidate should send a cover letter and CV (includes a publication list) to Dr. Neta Regev-Rudzki. For any informal inquiries please contact us by email at neta.regev-rudzki@weizmann.ac.il
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
We invite rotation students to join our research on malaria, immunology, host-pathogen interactions and extracellular vesicles.
More Information about MSc rotation
Our research combines molecular biology, microbiology, genetics (including CRISPR/Cas9), biochemistry, advanced imaging platforms, omics and biophysics.
Anyone interested or having questions, please email Professor Neta Regev-Rudzki:
neta.regev-rudzki@weizmann.ac.il
Department of Biomolecular Sciences
PhD position
We are seeking for highly motivated PhD STUDENTS.
The projects center on the cellular biology of the malaria parasite, immune response, parasite-host interaction and the field of cell-cell communication.
More Information about PhD position
Applicants with a research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics, imaging platforms or protein chemistry is advantageous.
Department of Biomolecular Sciences
MSc position
Our lab is open for ROTATION students
We invite rotation students to join our research on malaria parasite, immunology, host-pathogen interactions, cell communication and extracellular vesicles (cell-cell communication system).
More Information about MSc position
Our projects center on different fascinating molecular aspects of the cellular biology of the malaria parasite, combining imaging tools, biochemistry, omics, genetics (crispr) and biophysics.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 2nd,3rd
We invite rotation students to join our research on malaria, host-pathogen interactions and/or extracellular vesicles (cell-cell communication system). Our research combines molecular biology and genetics (including CRISPR/Cas9), biochemistry, advanced imaging platforms and analysis and/or biophysics.
Anyone interested or having questions, please email Professor Neta Regev-Rudzki.
neta.regev-rudzki@weizmann.ac.il
Department of Biomolecular Sciences
Postdoc position
Applicants with a strong research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms (including image analysis) or advanced protein chemistry is advantageous.
This is a full-time position available from June 2022 for a period of three years with a possibility of a further extension subject to funding availability.
Candidate should send a cover letter and CV (includes a publication list) to Dr. Neta Regev-Rudzki.
For any informal inquiries please contact us by email at
neta.regev-rudzki@weizmann.ac.il
Department of Biomolecular Sciences
PhD position
Applicants with a research background at the intersection of molecular biology, biochemistry, imaging and/or biophysics are encouraged to apply. Experience in microbiology, molecular genetics (including CRISPR/Cas9), advanced imaging platforms (including image analysis) or advanced protein chemistry is advantageous.
This is a full-time position available from June 2022 for a period of 4 years with a possibility of a further extension subject to funding availability.
Candidate should send a cover letter and CV (includes a publication list) to Dr. Neta Regev-Rudzki.
For any informal inquiries please contact us by email at
neta.regev-rudzki@weizmann.ac.il
Department of Brain Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Imaging the human brain: ultra-high field MRI and new biomarkers for brain function
More Information about MSc rotation
The study of Magnetic Resonance Imaging (MRI) and of functional MRI (fMRI) is a prime example of contemporary multidisciplinary science; where Physics, Chemistry, Biology and Engineering are combined. The study combines on one hand - physics background for development of new MRI techniques, on another - Neurobiology background to perform actual human volunteer studies. Our lab research focuses on ultra-high field MRI aiming to better understand the human brain function. To do so, we design basic functional MRI experiments to explore high temporal and spatial resolution capabilities and develop new MRI pulse sequences for functional and structural MRI.
Department of Biomolecular Sciences
PhD position
Discovering the mechanisms that control and coordinate the activity of molecular machines involved in the protein degradation pathway by combining native mass spectrometry and cell biology approaches
Department of Biomolecular Sciences
PhD position
Developing novel structural mass spectrometry methods
Department of Biomolecular Sciences
Postdoc position
Developing a computational approach to assign mass spectrometry data - a theoretical project.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Studying large protein complexes involved in the protein degradation pathway using a novel mass spectrometry approach.
Department of Chemical and Biological Physics
MSc rotation
Available Rotations: 2nd,3rd
Develop and study new biomimetic systems based on the cell cytoskeleton network capable of recapitulating some of the cell's most fundamental functions, such as emergence flows and high-order structures.
Department of Biomolecular Sciences
PhD position
Clocks resetting
How the clock integrates different resetting cues? Are there differences in resetting capacity between different cell types? How different pharmaceutics influence the clock? Can it be harnessed to improve therapy?
More Information about PhD position
Our lab has a longstanding interest in circadian clock resetting. We previously have identified and characterized novel resetting cues such as hypoxia and CO2. Recently, we have developed a new method to study resetting agents in vitro in an efficient and high-throughput manner, dubbed Circa-SCOPE. The method allows screening of multiple drugs in parallel to identify which affects the clock and how. Hence, it opens the door to a wide range of basic and translational research opportunities.
Department of Biomolecular Sciences
PhD position
Interactions between circadian clocks and exercise physiology
We employ various clock mutant mouse models with different light regimens to characterize the interaction between clocks and exercise. Further, we have designed and built fully automated time-controlled Running Wheels that can be programmed in advance to be in locked or unlocked positions for designated times to enable scheduled training of animals without manual interventions.
More Information about PhD position
Circadian clocks are key regulators of daily physiology and metabolism in mammals. Our understanding of the role of the circadian clock and specific clock proteins in controlling exercise capacity is rudimentary. Consequently, there is growing interest in exercise biology in general, specifically in its interaction with other processes that govern whole-body physiology and metabolism. We have reported that mice show a day-time variance in exercise capacity, and it is affected by exercise intensity and clock proteins and elicits a distinct muscle transcriptomic and metabolic signature. Specifically, we demonstrated that ZMP, an AMPK activator, is induced by exercise in a daytime-dependent manner. We continue to study various aspects of exercise physiology through the lens of circadian biology (Ezagouri et al., Cell Metabolism, 2019; Adamovich et al., Proc. Natl. Acad. Sci., 2021.).
Department of Biomolecular Sciences
PhD position
Oxygen and Circadian Clocks
How does chronic exposure to hypoxia, as occurs with people living at high altitude, affects the human clock? How oxygen is connected to exercise performance and is there a time preference for high altitude training? (Tripartite model for performance: Clocks, oxygen, and exercise) How does HIF-1a endogenously integrate with circadian clock complexes during the circadian cycle? How do HIF-1a and BMAL1 regulate rhythmic transcriptome?
More Information about PhD position
We demonstrated that low-amplitude oxygen cycles, which mimic the daily physiological cycles in oxygen levels observed in rodents, can reset the clock in a HIF-1a-dependent manner (Adamovich et al., Cell Metabolism 2017). Subsequently, we showed that oxygen and carbon dioxide rhythms are circadian clock controlled and differentially directed by behavioral signals (Adamovich et al., Cell Metabolism 2019). More recently we found that hypoxic conditions, as occur in sleep apnea, elicit circadian misalignment between clocks in different peripheral organs (Manella et al., P.N.A.S. 2020). We continue our venture to study the cross-talk between oxygen and circadian clocks at different levels.
Department of Biomolecular Sciences
Postdoc position
- Circadian exercise
-
In the past 7 years, we studied the cross-talk between metabolism and circadian rhythms, leading us to venture into other fields, like exercise biology. Some exciting questions, both related to physiology and molecular mechanism, that stem from our recent publications (Adamovich et al., Proc. Natl. Acad. Sci. USA, 2021; Ezagouri et al., Cell Metabolism, 2019) are now under investigation.
More Information about Postdoc position
The relevant projects address the influence of circadian clocks on exercise performance, and training efficiency, as well as the effect of chronotype, feeding, and hypoxia on exercise capacity.
Circadian clocks are key regulators of daily physiology and metabolism in mammals. Our understanding of the role of the circadian clock and specific clock proteins in controlling exercise capacity is rudimentary. Consequently, there is growing interest in exercise biology in general, specifically in its interaction with other processes that govern whole-body physiology and metabolism. We have reported that mice show a day-time variance in exercise capacity, and it is affected by exercise intensity and clock proteins and elicits a distinct muscle transcriptomic and metabolic signature. Specifically, we demonstrated that ZMP, an AMPK activator, is induced by exercise in a daytime-dependent manner. We continue to study various aspects of exercise physiology through the lens of circadian biology (Ezagouri et al., Cell Metabolism, 2019; Adamovich et al., Proc. Natl. Acad. Sci., 2021.).
We employ various clock mutant mouse models with different light regimens to characterize the interaction between clocks and exercise. Further, we have designed and built fully automated time-controlled Running Wheels that can be programmed in advance to be in locked or unlocked positions for designated times to enable scheduled training of animals without manual interventions. This experimental setup is optimized for addressing questions regarding the involvement of daytime and circadian clocks in regulating exercise capacity (Adamovich et al., STAR Protocols, 2021).
We are also studying the molecular clock and skeletal muscle metabolism in health and disease.
Department of Biomolecular Sciences
Postdoc position
-
Circadian clock resetting and Chrono-medicine
-
How the clock integrates different resetting cues? Are there differences in resetting capacity between different cell types? How different pharmaceutics influence the clock? Can it be harnessed to improve therapy?
More Information about Postdoc position
- Clocks resetting | Recently, we have developed a new method to study resetting agents in vitro in an efficient and high-throughput manner, dubbed Circa-SCOPE (Manella et al., Nature Communication 2021). This methodology opens the door to a wide range of applications, in both basic and translational research. For example, it allows screening multiple drugs (in-use or newly developed) in parallel to identify which affects the clock and how – with high relevance to chrono-medicine. It also allows the experimental testing of different models of clock resetting quantitatively. Hence, it opens the door to a wide range of basic and translational research opportunities.
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Biochemical identification of metabolic sensors
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
Computational analyses of rhythmic outputs (e.g. metabolites, gases)
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
The relationship between hypoxia and the core circadian clock
Department of Biomolecular Sciences
MSc rotation
Available Rotations: 1st,2nd,3rd
The interplay between circadian clocks and exercise performance
Department of Immunology and Regenerative Biology
PhD position
We are looking for a talented PhD student to join the lab. The project involves microbiology, immunology single cell tools and bioinformatic analysis. Prior knowledge is an advantage but not required.
More Information about PhD position
The laboratory of Dr. Roi Avraham, at the Weizmann Institute of Science, Israel, is looking for a PhD student position to study microbial manipulation of host immune response.
Encounters between immune cells and invading bacteria involves multiple host cell types with different attack strategies and counter-defenses by the bacteria. We are applying state-of-the-art single cell RNA-seq analysis of human PBMCs in response to intracellular bacterial infection, in order to build a fundamental understanding of how individual interactions between a bacterium and a host cell drive the outcome of infection. The project will revolve around understanding how Salmonella subvert immunity within the context of its host macrophage, to shed light on possible non-cell autonomous effects of internalized Salmonella to manipulate host immune responses.
The candidate must be highly motivated, enthusiastic, and an efficient researcher with a Msc in the relevant discipline, preferably microbiology. The applicant must be capable of working in a team, as well as to individually lead a research project. Excellent communication skills in both written and spoken English are required.
Department of Physics of Complex Systems
Postdoc position
Our research centers on the theory of complex systems and biophysics, applied to a broad spectrum of problems, mainly in the context of the physics of living systems. Our research is often done in collaboration with experimental groups. Key themes of our lab include mathematical modeling of cell growth and mechanics, both at the single-cell level and the population level, stochastic processes, disordered systems, and coarse-grained modeling of complex processes.
For more information and recent publications see: https://amir.seas.harvard.edu/
Department of Physics of Complex Systems
PhD position
Our research centers on the theory of complex systems and biophysics, applied to a broad spectrum of problems, mainly in the context of the physics of living systems. Our research is often done in collaboration with experimental groups. Key themes of our lab include mathematical modeling of cell growth and mechanics, both at the single-cell level and the population level, stochastic processes, disordered systems, and coarse-grained modeling of complex processes.
For more information and recent publications see: https://amir.seas.harvard.edu/
Department of Physics of Complex Systems
MSc position
Our research centers on the theory of complex systems and biophysics, applied to a broad spectrum of problems, mainly in the context of the physics of living systems. Our research is often done in collaboration with experimental groups. Key themes of our lab include mathematical modeling of cell growth and mechanics, both at the single-cell level and the population level, stochastic processes, disordered systems, and coarse-grained modeling of complex processes.
For more information and recent publications see: https://amir.seas.harvard.edu/
Department of Physics of Complex Systems
MSc position
Geometry, topology and order in soft materials
More Information about MSc position
Our group conducts theoretical study of various soft matter problems, typically ones that bring out geometry and topology as a crucial element in explaining observed physical phenomena (patterns, structures, mechanical properties, etc.). Our interests span many types of systems, materials and length scales, and includes liquid crystals, responsive smart materials, metamaterials, biological systems and more.
Department of Physics of Complex Systems
MSc position
Geometry, topology and order in soft materials
More Information about MSc position
Our group conducts theoretical study of various soft matter problems, typically ones that bring out geometry and topology as a crucial element in explaining observed physical phenomena (patterns, structures, mechanical properties, etc.). Our interests span many types of systems, materials and length scales, and includes liquid crystals, responsive smart materials, metamaterials, biological systems and more.
Department of Particle Physics and Astrophysics
PhD position
0-1 positions for Ph. D. students in theoretical high-energy physics, working on quantum field theory, string theory and/or quantum gravity
Department of Particle Physics and Astrophysics
MSc position
0-1 positions for M. Sc. students in theoretical high-energy physics, working on quantum field theory, string theory and/or quantum gravity