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December 01, 2013

  • Date:19SundayMarch 2017

    LINCing noncoding transcription to control of hepatic nutrient partitioning

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    Time
    15:00 - 16:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerDr. Jan-Wilhelm Kornfeld
    Max-Planck-Institute for Metabolism Research. Cologne, Germany
    Contact
    Lecture
  • Date:19SundayMarch 2017

    English Musical - Annie

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    Time
    18:30 - 18:30
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:20MondayMarch 2017

    Life Sciences Colloquium

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    Time
    11:00 - 12:00
    Title
    TBD
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Christine Jacobs- Wagner
    Department of Molecular, Cellular and Developmental Biology, Yale University, Microbial Pathogenesis Dept, Yale School of Medicine, Howard Hughes Medical Institute
    Contact
    Colloquia
  • Date:20MondayMarch 2017

    Recent advances in understanding the cellular roles of GSK-3 and its potential therapeutic implications

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    Time
    14:00 - 15:00
    Location
    Max and Lillian Candiotty Building
    LecturerProf. Hagit Eldar-Finkelman
    Professor of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv University
    Organizer
    Department of Immunology and Regenerative Biology
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    Lecture
  • Date:20MondayMarch 2017

    Afternoon Music - Asaf Ayalon host Alma Zohar

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    Time
    16:30 - 16:30
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:21TuesdayMarch 2017

    The shifting structure of the clathrin coat as revealed by correlative light and electron tomography

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    Time
    10:00 - 11:00
    Location
    Wolfson Building for Biological Research
    LecturerProf. Ori Avinoam
    Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Clathrin mediated endocytosis (CME) is a basic cellular func...»
    Clathrin mediated endocytosis (CME) is a basic cellular function playing essential roles in nutrient uptake, membrane recycling, synaptic transmission and viral infection. At the level of individual core components, CME might be considered well understood because we have an abundance of structural, biochemical, biophysical and dynamic information. However, researchers remain divided between two contradictory models for how clathrin coated vesicles (CCVs) form. The first, suggests that clathrin assembles as a planar lattice that subsequently bends as the membrane invaginates. For this to happen, complex rearrangements within the clathrin network must occur during budding. The second model avoids this difficulty by proposing that large flat clathrin lattices are not precursors of CME, and that at sites of CME, clathrin directly assembles to produce the curved coat as the membrane invaginates. To distinguish between these models, we applied a high precision correlative fluorescence microscopy (FM) and electron tomography (ET) approach to locate CCPs and obtain 3D information about their ultrastructure. We found that clathrin is recruited to the membrane early in endocytosis, before any significant membrane bending has occurred, and then rearranges as the membrane bends to wrap around the forming vesicle. Furthermore, we showed by FM that clathrin undergoes rapid exchange with the cytoplasmic pool at sites of endocytosis, providing insights into the mechanism driving coat rearrangement. To obtain structural information on the organization of the clathrin lattice at different stages of maturation, we performed correlated cryo -FM and -ET (Cryo-CLEM) on intact, genome edited mammalian cells expressing clathrin-GFP. We targeted sites of endocytosis using the fluorescence and resolved the positions of individual clathrin molecules within the assembled lattice. Our preliminary data suggests that lattice geometry changes during maturation from a flat sheet to a curved sphere. This fundamental knowledge in necessary to achieve a holistic understanding of this basic cellular function.

    Lecture
  • Date:21TuesdayMarch 2017

    Evaluating the Role of Water Availability in Determining the Yield/Plant Population Density Relationship

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    Time
    11:15 - 11:15
    Location
    Ullmann Building of Life Sciences
    LecturerDr. Shmulik Friedman
    Department of Environmental Physics and Irrigation, Institute of Soil, Water and Environmental Sciences, Agriculture Research Organization (ARO) Volcani Research Center, Bet Dagan
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    AbstractShow full text abstract about Thirty-eight yield/plant-population-density (Y-PPD) data set...»
    Thirty-eight yield/plant-population-density (Y-PPD) data sets were collected from the literature and analyzed statistically to yield, inter alia, a single "universal" relationship that realistically describes the Y-PPD data obtained with various plants in various agricultural and environmental conditions. The present study aims to facilitate evaluation of the dependence of water availability to plant-root systems on plant-population density, plant-arrangement geometry, active-root-system size, and soil texture. The outlined evaluation of the relative water uptake rate/plant-population-density (RWUR-PPD) relationship can quantify the roles of water availability and competition among neighboring root systems in determining the Y-PPD relationship. In particular, this methodology quantifies the effects of root system size, soil capillary length and planting rectangularity, on the Y-PPD relationship. Overall, the proposed RWUR evaluation shows, in reasonable qualitative agreement with experimental findings, that the Y-PPD relationship increases with increasing root system radius and soil capillary length, and with decreasing rectangularity. RWUR evaluation shows that interplant competition for water increases approximately linearly with the product of (root-system radius) × (soil capillary length). The water-competition factor is approximately equal to 4 r01-1, i.e. to the surface area of a sphere with a radius equal to the geometric mean of the radius of root system (r0) and the soil capillary length (-1). Plant roots and shoots compete also for resources other than water, e.g., soil nutrients and oxygen and solar radiation. Thus, the agronomically important Y-PPD relationship depends on genetic, agricultural, and environmental factors that affect availability of other resources differently from their effects on water availability; and these differences render it virtually impossible to define and quantify the roles of the various essential resources and the effects of diverse factors in determining the Y-PPD relationship. This is why practical agronomists use empirical mathematical expressions to describe Y-PPD.
    Lecture
  • Date:21TuesdayMarch 2017

    Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?

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    Time
    12:00 - 12:00
    Title
    Viruses: Friend or Foe?
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Noam Stern-Ginossar
    Organizer
    Communications and Spokesperson Department
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    Contact
    Lecture
  • Date:21TuesdayMarch 2017

    Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?

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    Time
    12:00 - 12:00
    Title
    Viruses: Friend or Foe?
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Noam Stern-Ginossar
    Organizer
    Communications and Spokesperson Department
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    Contact
    Lecture
  • Date:21TuesdayMarch 2017

    Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?

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    Time
    12:00 - 12:00
    Title
    Viruses: Friend or Foe?
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Noam Stern-Ginossar
    Organizer
    Communications and Spokesperson Department
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    Contact
    Lecture
  • Date:21TuesdayMarch 2017

    Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?

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    Time
    12:00 - 12:00
    Title
    Viruses: Friend or Foe?
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Noam Stern-Ginossar
    Organizer
    Communications and Spokesperson Department
    Homepage
    Contact
    Lecture
  • Date:21TuesdayMarch 2017

    Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?

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    Time
    12:00 - 12:00
    Title
    Viruses: Friend or Foe?
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Noam Stern-Ginossar
    Organizer
    Communications and Spokesperson Department
    Homepage
    Contact
    Lecture
  • Date:21TuesdayMarch 2017

    MCB - Students seminar

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    Time
    12:15 - 12:15
    Title
    TBA
    Location
    Wolfson Building for Biological Research
    Organizer
    Department of Molecular Cell Biology
    Contact
    Lecture
  • Date:21TuesdayMarch 2017

    Chemical love – The molecular neuroetholgy of pheromonal communication

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    Time
    12:30 - 12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Yehuda Ben-Shahar
    Washington University School of Medicine Washington University
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about Research in the Ben-Shahar lab at Washington University in S...»
    Research in the Ben-Shahar lab at Washington University in St. Louis is focused on several integrative projects at the interface of evolution, genetics, and neuroethology. Specifically, research in the lab follows two major themes: 1) The genetic and neuronal processes that regulate the interactions between individual animals and their social environment, including the evolution and signaling mechanisms associated with pheromonal communication in insects, and the neuronal circuits that drive pheromone-induced behaviors; 2) the molecular evolution and genetics of the neuronal stress response, with a specific focus on mechanistic tradeoffs between neuronal robustness and cognition.
    Lecture
  • Date:21TuesdayMarch 2017

    AMO Special Seminar

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    Time
    13:15 - 14:15
    Title
    The delay-time distribution in scattering of ultra-short light pulses from complex targets
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerProf. Uzy Smilansky
    Physics of Complex Systems, Weizmann
    Organizer
    Department of Physics of Complex Systems
    Contact
    AbstractShow full text abstract about When time-narrow wave-packets scatter by complex target, th...»
    When time-narrow wave-packets scatter by complex target, the field is trapped for some time, and emerges as a time broadened pulse, whose shape reflects the distribution of the delay (trapping) -times. I shall present a comprehensive framework for the computation of the delay-time distribution, and its dependence on the scattering dynamics, the wave-packet envelope (profile) and the dispersion relation. I shall then show how the well-known Wigner-Smith mean delay time and the semi-classical approximation emerge as limiting cases, valid only under special circumstances. For scattering on random media, localization has a drastic effect on the delay-time distribution. I shall demonstrate it for a particular one-dimensional system which can be analytically solved.
    Lecture
  • Date:21TuesdayMarch 2017

    Chemical Physics Department Guest Seminar

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    Time
    15:00 - 15:00
    Title
    Neural Control of Abundant Systems as Local Algorithms Stabilizing Subspaces
    Location
    Perlman Chemical Sciences Building
    LecturerProf Vladimir Akulin
    Laboratoire Aime Cotton CNRS, France
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about We address the problem of stability of motor actions impleme...»
    We address the problem of stability of motor actions implemented by the central nervous system based on simple algorithms potentially reflecting physical (including physiological) processes within the body. A number of conceptually simple algorithms that solve motor tasks with a high probability of success may be based on feedback schemes that ensure stability of subspaces of neural variables associated with accomplishing those tasks. The task is formulated in terms of linear constrains imposed either on the human body mechanical variables or on neural variables; we discuss three reference frames relevant to these processes. We discuss underlying basic principles of such algorithms, their architecture, and efficiency, and compare the outcomes of implementation of such algorithms with the results of experiments performed on the human hand.
    Lecture
  • Date:21TuesdayMarch 2017

    Peter Pan - Children's theater

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    Time
    17:30 - 17:30
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:22WednesdayMarch 2017

    "Glass Ceiling and Power Inequality in Social Network"

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    Time
    11:00 - 11:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. David Peleg
    Dean, Mathematics and Computer Science faculty
    Organizer
    Department of Chemical and Biological Physics
    Contact
    Lecture
  • Date:23ThursdayMarch 2017

    Properties of Elementary Particles Fluxes and their Ratios in Cosmic Rays

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerAndrei Kounine
    Cern
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about The Alpha Magnetic Spectrometer is a state-of-art particle p...»
    The Alpha Magnetic Spectrometer is a state-of-art particle physics detector
    collecting data on the International Space Station since May 2011. Precision
    measurements of all elementary charged cosmic ray particles have been
    performed by AMS using a data sample of 85 billion events collected during the
    first five years of operations on the Station. The latest AMS results on the fluxes
    and flux ratios of the elementary cosmic ray particles show unique features that
    require accurate theoretical interpretation of their origin, be it from dark matter
    collisions or new astrophysical sources.
    Colloquia
  • Date:23ThursdayMarch 2017

    Local motion signals: statistics, responses and generative models

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    Time
    14:30 - 14:30
    Location
    Nella and Leon Benoziyo Building for Brain Research
    LecturerDr. Eyal Nitzany
    Dept of Physics and Astronomy, Northwestern University and Dept of Organismal Biology and Anatomy, University of Chicago
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about Many visual tasks, such as separation of figures from ground...»
    Many visual tasks, such as separation of figures from ground and navigation, benefit from the extraction and the usage of local motion signals. Yet, there are many ways in which local motion signals are being represented (mostly based on mathematical and computational considerations). I’ll begin this talk by presenting a computational work that explored whether specific kinds of local motion signals occur in the natural world (Nitzany&Victor, 2014, Journal of Vision).
    Next, I will present the results of a neurophysiological experiment where we recorded from the main visual brain areas of two visually accomplished, but very different, animals—macaque monkeys and dragonflies. We found similar responses to local motion signals across species, which may serve as neurophysiologic evidence that mammalian visual cortex and the visual centers of the dragonfly brain process motion using similar algorithms and may have converged on a common computational scheme for detecting visual motion.
    Finally, I’ll present our current work, which extends and manipulates a few machine learning techniques to generate novel stimuli, where specific characteristics, with regards to local motion signals, are being preserved.
    If time permits, I will discuss another line of work (Menda et. al., 2014, Current Biology, Shamble et. al., 2016, Current Biology), where we were able to record from neurons of jumping spiders. I will explain our approach that enables us to record from those tiny marvelous creatures and review our main findings with regards to visual and auditory cues.

    Lecture

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