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December 01, 2013
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Date:19SundayMarch 2017Lecture
LINCing noncoding transcription to control of hepatic nutrient partitioning
More information Time 15:00 - 16:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Jan-Wilhelm Kornfeld
Max-Planck-Institute for Metabolism Research. Cologne, GermanyContact -
Date:19SundayMarch 2017Cultural Events
English Musical - Annie
More information Time 18:30 - 18:30Location Michael Sela AuditoriumContact -
Date:20MondayMarch 2017Colloquia
Life Sciences Colloquium
More information Time 11:00 - 12:00Title TBDLocation Dolfi and Lola Ebner AuditoriumLecturer Prof. Christine Jacobs- Wagner
Department of Molecular, Cellular and Developmental Biology, Yale University, Microbial Pathogenesis Dept, Yale School of Medicine, Howard Hughes Medical InstituteContact -
Date:20MondayMarch 2017Lecture
Recent advances in understanding the cellular roles of GSK-3 and its potential therapeutic implications
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Hagit Eldar-Finkelman
Professor of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv UniversityOrganizer Department of Immunology and Regenerative BiologyContact -
Date:20MondayMarch 2017Cultural Events
Afternoon Music - Asaf Ayalon host Alma Zohar
More information Time 16:30 - 16:30Location Michael Sela AuditoriumContact -
Date:21TuesdayMarch 2017Lecture
The shifting structure of the clathrin coat as revealed by correlative light and electron tomography
More information Time 10:00 - 11:00Location Wolfson Building for Biological ResearchLecturer Prof. Ori Avinoam
Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Clathrin mediated endocytosis (CME) is a basic cellular func...» Clathrin mediated endocytosis (CME) is a basic cellular function playing essential roles in nutrient uptake, membrane recycling, synaptic transmission and viral infection. At the level of individual core components, CME might be considered well understood because we have an abundance of structural, biochemical, biophysical and dynamic information. However, researchers remain divided between two contradictory models for how clathrin coated vesicles (CCVs) form. The first, suggests that clathrin assembles as a planar lattice that subsequently bends as the membrane invaginates. For this to happen, complex rearrangements within the clathrin network must occur during budding. The second model avoids this difficulty by proposing that large flat clathrin lattices are not precursors of CME, and that at sites of CME, clathrin directly assembles to produce the curved coat as the membrane invaginates. To distinguish between these models, we applied a high precision correlative fluorescence microscopy (FM) and electron tomography (ET) approach to locate CCPs and obtain 3D information about their ultrastructure. We found that clathrin is recruited to the membrane early in endocytosis, before any significant membrane bending has occurred, and then rearranges as the membrane bends to wrap around the forming vesicle. Furthermore, we showed by FM that clathrin undergoes rapid exchange with the cytoplasmic pool at sites of endocytosis, providing insights into the mechanism driving coat rearrangement. To obtain structural information on the organization of the clathrin lattice at different stages of maturation, we performed correlated cryo -FM and -ET (Cryo-CLEM) on intact, genome edited mammalian cells expressing clathrin-GFP. We targeted sites of endocytosis using the fluorescence and resolved the positions of individual clathrin molecules within the assembled lattice. Our preliminary data suggests that lattice geometry changes during maturation from a flat sheet to a curved sphere. This fundamental knowledge in necessary to achieve a holistic understanding of this basic cellular function.
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Date:21TuesdayMarch 2017Lecture
Evaluating the Role of Water Availability in Determining the Yield/Plant Population Density Relationship
More information Time 11:15 - 11:15Location Ullmann Building of Life SciencesLecturer Dr. Shmulik Friedman
Department of Environmental Physics and Irrigation, Institute of Soil, Water and Environmental Sciences, Agriculture Research Organization (ARO) Volcani Research Center, Bet DaganOrganizer Department of Plant and Environmental SciencesContact Abstract Show full text abstract about Thirty-eight yield/plant-population-density (Y-PPD) data set...» Thirty-eight yield/plant-population-density (Y-PPD) data sets were collected from the literature and analyzed statistically to yield, inter alia, a single "universal" relationship that realistically describes the Y-PPD data obtained with various plants in various agricultural and environmental conditions. The present study aims to facilitate evaluation of the dependence of water availability to plant-root systems on plant-population density, plant-arrangement geometry, active-root-system size, and soil texture. The outlined evaluation of the relative water uptake rate/plant-population-density (RWUR-PPD) relationship can quantify the roles of water availability and competition among neighboring root systems in determining the Y-PPD relationship. In particular, this methodology quantifies the effects of root system size, soil capillary length and planting rectangularity, on the Y-PPD relationship. Overall, the proposed RWUR evaluation shows, in reasonable qualitative agreement with experimental findings, that the Y-PPD relationship increases with increasing root system radius and soil capillary length, and with decreasing rectangularity. RWUR evaluation shows that interplant competition for water increases approximately linearly with the product of (root-system radius) × (soil capillary length). The water-competition factor is approximately equal to 4 r01-1, i.e. to the surface area of a sphere with a radius equal to the geometric mean of the radius of root system (r0) and the soil capillary length (-1). Plant roots and shoots compete also for resources other than water, e.g., soil nutrients and oxygen and solar radiation. Thus, the agronomically important Y-PPD relationship depends on genetic, agricultural, and environmental factors that affect availability of other resources differently from their effects on water availability; and these differences render it virtually impossible to define and quantify the roles of the various essential resources and the effects of diverse factors in determining the Y-PPD relationship. This is why practical agronomists use empirical mathematical expressions to describe Y-PPD. -
Date:21TuesdayMarch 2017Lecture
Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?
More information Time 12:00 - 12:00Title Viruses: Friend or Foe?Location Dolfi and Lola Ebner AuditoriumLecturer Prof. Noam Stern-Ginossar Organizer Communications and Spokesperson DepartmentHomepage Contact -
Date:21TuesdayMarch 2017Lecture
Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?
More information Time 12:00 - 12:00Title Viruses: Friend or Foe?Location Dolfi and Lola Ebner AuditoriumLecturer Prof. Noam Stern-Ginossar Organizer Communications and Spokesperson DepartmentHomepage Contact -
Date:21TuesdayMarch 2017Lecture
Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?
More information Time 12:00 - 12:00Title Viruses: Friend or Foe?Location Dolfi and Lola Ebner AuditoriumLecturer Prof. Noam Stern-Ginossar Organizer Communications and Spokesperson DepartmentHomepage Contact -
Date:21TuesdayMarch 2017Lecture
Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?
More information Time 12:00 - 12:00Title Viruses: Friend or Foe?Location Dolfi and Lola Ebner AuditoriumLecturer Prof. Noam Stern-Ginossar Organizer Communications and Spokesperson DepartmentHomepage Contact -
Date:21TuesdayMarch 2017Lecture
Dr. Noam Stern-Ginossar - Viruses: Friend or Foe?
More information Time 12:00 - 12:00Title Viruses: Friend or Foe?Location Dolfi and Lola Ebner AuditoriumLecturer Prof. Noam Stern-Ginossar Organizer Communications and Spokesperson DepartmentHomepage Contact -
Date:21TuesdayMarch 2017Lecture
MCB - Students seminar
More information Time 12:15 - 12:15Title TBALocation Wolfson Building for Biological ResearchOrganizer Department of Molecular Cell BiologyContact -
Date:21TuesdayMarch 2017Lecture
Chemical love – The molecular neuroetholgy of pheromonal communication
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Yehuda Ben-Shahar
Washington University School of Medicine Washington UniversityOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Research in the Ben-Shahar lab at Washington University in S...» Research in the Ben-Shahar lab at Washington University in St. Louis is focused on several integrative projects at the interface of evolution, genetics, and neuroethology. Specifically, research in the lab follows two major themes: 1) The genetic and neuronal processes that regulate the interactions between individual animals and their social environment, including the evolution and signaling mechanisms associated with pheromonal communication in insects, and the neuronal circuits that drive pheromone-induced behaviors; 2) the molecular evolution and genetics of the neuronal stress response, with a specific focus on mechanistic tradeoffs between neuronal robustness and cognition. -
Date:21TuesdayMarch 2017Lecture
AMO Special Seminar
More information Time 13:15 - 14:15Title The delay-time distribution in scattering of ultra-short light pulses from complex targetsLocation Edna and K.B. Weissman Building of Physical SciencesLecturer Prof. Uzy Smilansky
Physics of Complex Systems, WeizmannOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about When time-narrow wave-packets scatter by complex target, th...» When time-narrow wave-packets scatter by complex target, the field is trapped for some time, and emerges as a time broadened pulse, whose shape reflects the distribution of the delay (trapping) -times. I shall present a comprehensive framework for the computation of the delay-time distribution, and its dependence on the scattering dynamics, the wave-packet envelope (profile) and the dispersion relation. I shall then show how the well-known Wigner-Smith mean delay time and the semi-classical approximation emerge as limiting cases, valid only under special circumstances. For scattering on random media, localization has a drastic effect on the delay-time distribution. I shall demonstrate it for a particular one-dimensional system which can be analytically solved. -
Date:21TuesdayMarch 2017Lecture
Chemical Physics Department Guest Seminar
More information Time 15:00 - 15:00Title Neural Control of Abundant Systems as Local Algorithms Stabilizing SubspacesLocation Perlman Chemical Sciences BuildingLecturer Prof Vladimir Akulin
Laboratoire Aime Cotton CNRS, FranceOrganizer Department of Chemical and Biological PhysicsContact Abstract Show full text abstract about We address the problem of stability of motor actions impleme...» We address the problem of stability of motor actions implemented by the central nervous system based on simple algorithms potentially reflecting physical (including physiological) processes within the body. A number of conceptually simple algorithms that solve motor tasks with a high probability of success may be based on feedback schemes that ensure stability of subspaces of neural variables associated with accomplishing those tasks. The task is formulated in terms of linear constrains imposed either on the human body mechanical variables or on neural variables; we discuss three reference frames relevant to these processes. We discuss underlying basic principles of such algorithms, their architecture, and efficiency, and compare the outcomes of implementation of such algorithms with the results of experiments performed on the human hand. -
Date:21TuesdayMarch 2017Cultural Events
Peter Pan - Children's theater
More information Time 17:30 - 17:30Location Michael Sela AuditoriumContact -
Date:22WednesdayMarch 2017Lecture
"Glass Ceiling and Power Inequality in Social Network"
More information Time 11:00 - 11:00Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. David Peleg
Dean, Mathematics and Computer Science facultyOrganizer Department of Chemical and Biological PhysicsContact -
Date:23ThursdayMarch 2017Colloquia
Properties of Elementary Particles Fluxes and their Ratios in Cosmic Rays
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Andrei Kounine
CernOrganizer Faculty of PhysicsContact Abstract Show full text abstract about The Alpha Magnetic Spectrometer is a state-of-art particle p...» The Alpha Magnetic Spectrometer is a state-of-art particle physics detector
collecting data on the International Space Station since May 2011. Precision
measurements of all elementary charged cosmic ray particles have been
performed by AMS using a data sample of 85 billion events collected during the
first five years of operations on the Station. The latest AMS results on the fluxes
and flux ratios of the elementary cosmic ray particles show unique features that
require accurate theoretical interpretation of their origin, be it from dark matter
collisions or new astrophysical sources.
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Date:23ThursdayMarch 2017Lecture
Local motion signals: statistics, responses and generative models
More information Time 14:30 - 14:30Location Nella and Leon Benoziyo Building for Brain ResearchLecturer Dr. Eyal Nitzany
Dept of Physics and Astronomy, Northwestern University and Dept of Organismal Biology and Anatomy, University of ChicagoOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Many visual tasks, such as separation of figures from ground...» Many visual tasks, such as separation of figures from ground and navigation, benefit from the extraction and the usage of local motion signals. Yet, there are many ways in which local motion signals are being represented (mostly based on mathematical and computational considerations). I’ll begin this talk by presenting a computational work that explored whether specific kinds of local motion signals occur in the natural world (Nitzany&Victor, 2014, Journal of Vision).
Next, I will present the results of a neurophysiological experiment where we recorded from the main visual brain areas of two visually accomplished, but very different, animals—macaque monkeys and dragonflies. We found similar responses to local motion signals across species, which may serve as neurophysiologic evidence that mammalian visual cortex and the visual centers of the dragonfly brain process motion using similar algorithms and may have converged on a common computational scheme for detecting visual motion.
Finally, I’ll present our current work, which extends and manipulates a few machine learning techniques to generate novel stimuli, where specific characteristics, with regards to local motion signals, are being preserved.
If time permits, I will discuss another line of work (Menda et. al., 2014, Current Biology, Shamble et. al., 2016, Current Biology), where we were able to record from neurons of jumping spiders. I will explain our approach that enables us to record from those tiny marvelous creatures and review our main findings with regards to visual and auditory cues.
