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January 12, 2015
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Date:09MondayFebruary 2015Cultural Events
"Nana Salima baeer hagdola"
More information Time 20:30 - 22:45Title Iraqi playLocation Michael Sela AuditoriumContact -
Date:10TuesdayFebruary 2015Lecture
mechanisms of nuclear positioning during cell migration and muscle formation
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Edgar R. Gomes
Instituto de Medicina Molecular Faculdade de Medicina da Universidade de Lisboa, PortugalOrganizer Department of Molecular GeneticsContact -
Date:10TuesdayFebruary 2015Lecture
Grounds states of the stationary Choquard equations
More information Time 11:00 - 11:00Location Jacob Ziskind BuildingLecturer Vitaly Moroz
Swansea University, UKOrganizer Faculty of Mathematics and Computer ScienceContact -
Date:10TuesdayFebruary 2015Lecture
Evidences of metabolic competition between methionine and glutathione biosynthetic pathways
More information Time 11:15 - 11:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Rachel Amir
Plant metabolism laboratory, MIGAL, Galilee Research Institute, Northern IsraelOrganizer Department of Plant and Environmental SciencesContact Abstract Show full text abstract about http://www.migal.org.il/Rachel-Amir ...» http://www.migal.org.il/Rachel-Amir -
Date:10TuesdayFebruary 2015Lecture
DNA interrogation by the CRISPR RNA-guided Endonucluease Cas9
More information Time 11:30 - 11:30Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Samuel H. Sternberg
Doudna Laboratory, Dept. of Chemistry, University of California, Berkeley, USAContact Abstract Show full text abstract about Cas9 is an RNA-guided DNA endonuclease found in clustered re...» Cas9 is an RNA-guided DNA endonuclease found in clustered regularly interspaced short palindromic repeats (CRISPR) bacterial immune systems. Recently, Cas9 and CRISPR-derived guide RNAs have been repurposed for powerful genome engineering applications in plants and animals, yet the underlying molecular cues that enable programmable DNA recognition have been poorly understood. Using a combination of structural, biochemical, and single-molecule approaches, we determined the mechanisms of DNA target search and recognition. We show that Cas9 consists of two structural lobes that undergo RNA-induced conformational changes to create a central DNA-binding channel. DNA binding requires the initial recognition of a short trinucleotide motif known as the PAM, and PAM interactions trigger Cas9 catalytic activity. Building on these insights, we developed new applications including programmable RNA manipulation with Cas9, and a split-Cas9 enzyme that will enable enhanced spatiotemporal control of genome engineering events in cells. Finally, ongoing work with evolutionarily related CRISPR-Cas immune systems has revealed how distinct RNA-guided protein complexes have converged on common mechanisms of target recognition. -
Date:10TuesdayFebruary 2015Lecture
Human Papillomavirus and Cancer, Viral Genomics, Evolution and Pathogenesis in Humans
More information Time 15:00 - 15:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Robert D. Burk Organizer Department of Molecular GeneticsContact -
Date:10TuesdayFebruary 2015Cultural Events
"Habait Shel Yael"
More information Time 17:30 - 19:00Title Children's theatreLocation Michael Sela AuditoriumContact -
Date:11WednesdayFebruary 2015Lecture
Isometric scaling in developing long bones is achieved by an optimal epiphyseal growth balance
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Elazar Zelzer
Dept. of Molecular Genetics, WISContact -
Date:11WednesdayFebruary 2015Lecture
Algebraic Geometry and Representation Theory Seminar
More information Time 11:00 - 12:30Title gl(infty) and Deligne categoriesLocation Jacob Ziskind BuildingLecturer Vera Serganova
University of California, BerkeleyContact -
Date:11WednesdayFebruary 2015Lecture
Science with orbital phase curves in the space age
More information Time 11:15 - 12:00Location Nella and Leon Benoziyo Physics BuildingLecturer Avi Shporer
Sagan Fellow, Caltech/JPLOrganizer Nella and Leon Benoziyo Center for AstrophysicsContact Abstract Show full text abstract about Advancements in the field of observational astronomy are usu...» Advancements in the field of observational astronomy are usually limited by technological capabilities. In the current era technology has allowed for space-based surveys delivering a growing sample of high quality time series photometry. This has finally enabled the detailed study of variability along the orbital motion, or orbital phase, of stellar binaries and star-planet systems. These orbital modulations are induced by a combination of gravitational and atmospheric processes. Gravitational processes include the beaming effect (also known as Doppler boosting) and tidal ellipsoidal distortion, so the photometric light curve shape is sensitive to the companion’s mass and orbit’s shape. Atmospheric processes include reflection of light and thermal emission by the companion, making phase curves a tool for probing the companion’s atmosphere. Therefore, the study of phase curves has a large scientific potential, which we have only begun to explore in recent years. I will present the science done with phase curves, including the mass measurement of companions to hot early-type stars (where the mass cannot be measured using radial velocities), the search for non-eclipsing systems, and the study of the companions’ atmosphere. Finally, I will briefly discuss the study of phase curves with current and future space-based surveys including K2, TESS, and PLATO. -
Date:12ThursdayFebruary 2015Lecture
Magnetic Resonance Seminar
More information Time 09:30 - 09:30Title The Role of ESR in Determining Structure, Dynamics, and Function of Protein Complexes and SuperstructuresLocation Gerhard M.J. Schmidt Lecture HallLecturer Prof. Jack Freed
Cornell University, NY, USAOrganizer Department of Chemical and Biological PhysicsContact -
Date:12ThursdayFebruary 2015Lecture
Geometric Functional Analysis and Probability Seminar
More information Time 11:05 - 01:00Title Invariants of Random Knots and LinksLocation Jacob Ziskind BuildingLecturer Chaim Even Zohar
Hebrew University of JerusalemContact Abstract Show full text abstract about We study random knots and links in R^3 using the Petaluma mo...» We study random knots and links in R^3 using the Petaluma model, which is based on the petal projections developed by Adams et al. (2012).
In this model we obtain a formula for the distribution of the linking number of a random two-component link. We also obtain formulas for the expectations and the higher moments of the Casson invariant and the order-three knot invariant v3. These are the first precise formulas given for the distributions of invariants in any model for random knots or links.
All terms above will be defined and explained.
Joint work with Joel Hass, Nati Linial, and Tahl Nowik. -
Date:12ThursdayFebruary 2015Colloquia
Scaling arguments and many-body physics to predict
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Phillipe Cluzel
HarvardOrganizer Faculty of PhysicsContact Abstract Show full text abstract about An outstanding problem in medicine is to combat bacteria res...» An outstanding problem in medicine is to combat bacteria resistant to antibiotics and cancer cells resistant to chemotherapy treatments. Drug combinations are often used to counter resistance, but therapies developed on drug-sensitive cells often fail when applied to resistant mutants. The talk will describe a series of experiments and theoretical approaches using scaling arguments, to infer the response of resistant cancer cells and bacteria to multidrug treatments. I will show that general symmetry arguments are sufficient to unify the behaviors of drug-resistant and drug-sensitive cells. Experiments validate this approach, which holds for many cell types across several domains of life. Thus, such simplifying arguments may foster our understanding of drug resistance even before specific detailed biochemical mecha-nisms have been elucidated.
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Date:12ThursdayFebruary 2015Lecture
Type II Innate Immunity
More information Time 11:30 - 11:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. William E. Paul
National Institutes of Health Distinguished Investigator Chief, Laboratory of ImmunologyOrganizer Department of Systems ImmunologyContact -
Date:14SaturdayFebruary 2015Cultural Events
"Kol echad vemazalo"
More information Time 21:00 - 22:45Title Morrocan comedy playLocation Michael Sela AuditoriumContact -
Date:15SundayFebruary 2015Conference
The Sounds of PHOTOSYNTHESIS -Symposium on the 80th Birthday of Shmuel Malkin
More information Time 09:00 - 16:30Location The David Lopatie Conference CentreChairperson Avigdor Scherz -
Date:15SundayFebruary 2015Lecture
The effect of mechanical force on the free-energy landscape of proteins in single molecule experiments
More information Time 11:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Dr. Ronen Berkovich
Department of Chemical Engineering, Ben Gurion UniversityOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:15SundayFebruary 2015Lecture
To be announced
More information Time 13:00 - 13:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Sarit Flohr Edelheit
Rotem Sorek's group, Dept. of Molecular GeneticsContact -
Date:16MondayFebruary 2015Conference
WIS CRISPR WORKSHOP
More information Time All dayLocation Arthur and Rochelle Belfer Building for Biomedical ResearchChairperson Rebecca Haffner-KrauszHomepage Contact -
Date:16MondayFebruary 201518WednesdayFebruary 2015Conference
Computational Challenges in Large Scale Image Analysis
More information Time All dayLocation The David Lopatie Conference CentreChairperson Boaz NadlerContact