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April 30, 2015

  • Date:27WednesdayDecember 2017

    Developmental Club Series 2017-2018

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    Time
    10:00 - 11:00
    Title
    “Decoding the regulatory information in genomes: lessons from enhancer evolution”
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerElla Preger-Ben Noon
    HHMI Janelia Research Campus
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:27WednesdayDecember 2017

    Serotonin's roles in learning and decision-making

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    Time
    10:30 - 10:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerDr. Eran Lottem
    Champalimaud Centre for the Unknown, Lisbon
    Organizer
    Department of Brain Sciences
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    Lecture
  • Date:28ThursdayDecember 2017

    Magnetic Resonance Seminar

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    Time
    09:30 - 09:30
    Title
    From Lex's adiabatic pulses to phase-modulated saturation pulses:‎ pushing the limits of quadrupolar NMR
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Amir Goldbourt‎‎
    Tel Aviv University
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about The periodic table is dominated by nuclei having a nuclear s...»
    The periodic table is dominated by nuclei having a nuclear spin larger than one-half, which possess a quadrupolar interaction, or spins having extensively large chemical shift anisotropies. The bottleneck in manipulating such spins is the low bandwidth, hence excitation efficiency, of conventional RF pulses. The demonstration of the spin locking mechanism in quadrupolar spins undergoing magic-angle spinning (A.J. Vega, JMR 96, 50, 1992) allowed the development of efficient quadrupolar-spin 1/2 distance measurements using sequences such as TRAPDOR and REAPDOR. Yet, adiabaticity fails for large quadrupolar couplings or at fast spinning rates, which are common in today's hardware, again due to insufficient RF power. Several developments to overcome this "sudden passage" limit have been proposed in recent years pushing the limit of nuclei that can be analyzed efficiently. I will discuss these advances, and show how our phase-modulated pulse approach provides complete randomization of all powder crystallites and consequently generates macroscopic spin saturation. As a result, distances to quadrupolar nuclei with extremely large couplings can be measured accurately and efficiently (up to frequencies of 10s of MHz), and reliable lifetimes of quadrupolar spins can be determined.
    Lecture
  • Date:28ThursdayDecember 2017

    Special Colloquium in honor of Prof. Shimon Levit’s 70th birthday

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerMario Livio
    UCL
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about HUMAN CURIOSITY The ability to ask “why?” makes us uniquely...»
    HUMAN CURIOSITY
    The ability to ask “why?” makes us uniquely human. Curiosity drives basic scientific research, is the engine behind creativity in all disciplines from the arts to technology, is a necessary ingredient in education, and a facilitating tool in every form of storytelling (literature, film, TV, or even a simple conversation) that delights rather than bores. In a fascinating and entertaining lecture, astrophysicist and bestselling author Mario Livio surveys and interprets cutting-edge research in psychology and neuroscience that aims at exploring and understanding the origin and mechanisms of human curiosity. As part of his research into the subject, Livio examined in detail the personalities of two individuals who arguably represent the most curious minds to have ever existed: Leonardo da Vinci and Richard Feynman. He also interviewed 9 exceptionally curious people living today, among them Fabiola Gianotti, the Director General of CERN (who is also an accomplished pianist), paleontologist Jack Horner, and the virtuoso lead guitarist of the rock band Queen, Brian May (who also holds a PhD in astrophysics), and Livio presents fascinating conclusions from these conversations.
    Colloquia
  • Date:28ThursdayDecember 2017

    Genomic approaches to studying cancer aneuploidy

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    Time
    11:15 - 11:15
    Location
    Wolfson Building for Biological Research
    LecturerDr. Uri Ben-David
    Broad Institute Cambridge, Massachusetts
    Organizer
    Department of Molecular Cell Biology
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    Lecture
  • Date:28ThursdayDecember 2017

    Special Guest Seminar

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    Time
    12:00 - 13:00
    Title
    A journey with cytoplasmic receptors NOD1&2 and Human Cytomegalovirus- from bedside to bench and back
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerRavit Boger, MD
    Associate Professor of Pediatrics Division of Infectious Diseases Johns Hopkins Hospital
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:28ThursdayDecember 2017

    Pelletron meeting (by invitation only)

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    Time
    16:00 - 18:00
    Location
    Dolfi and Lola Ebner Auditorium
    Contact
    Lecture
  • Date:31SundayDecember 2017

    The National Mathematical Olympiad in memory of Prof. Joseph Gillis

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    Time
    11:00 - 16:00
    Organizer
    Faculty of Mathematics and Computer Science
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    Lecture
  • Date:31SundayDecember 2017

    An information machine with tunable correlations based on colloid particle diffusion

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    Time
    11:00 - 12:00
    Location
    Perlman Chemical Sciences Building
    LecturerDr. Yael Roichman
    School of Chemistry, TAU
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    AbstractShow full text abstract about We realize experimentally an information machine converting ...»
    We realize experimentally an information machine converting information to work. Our experimental design is comprised of a colloidal particle diffusing in a microfluidic channel, with a repelling laser based barrier that is moved in feedback to the measured particle position. In a quasi-static mode of operation, the amount of used information is related to the Shannon entropy of uncorrelated steps. We develop a scheme to calculate this information at steady state at fast operation, which induces temporal correlations. We use this calculation to characterize the output power and efficiency of our information machine as a function of feedback cycle time.
    Lecture
  • Date:31SundayDecember 2017

    Fine-scale planktonic systems: characteristics and processes

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    Time
    11:00 - 11:00
    Location
    Sussman Family Building for Environmental Sciences
    LecturerYoav Lehahn
    Haifa University
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    Lecture
  • Date:31SundayDecember 2017

    High precision correlated light and electron microscopy

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    Time
    15:00 - 16:00
    Location
    Camelia Botnar Building
    LecturerProf. Ori Avinoam
    Organizer
    Department of Life Sciences Core Facilities
    Contact
    Lecture
  • Date:01MondayJanuary 2018

    "Chiral Single-Walled Carbon Nanotubes – New Platforms for Spintronics"

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    Time
    11:00 - 12:15
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Michael J. Therien
    Duke University
    Organizer
    Faculty of Chemistry
    Contact
    Colloquia
  • Date:01MondayJanuary 2018

    Chemical and Biological Physics Dept Guest Seminar

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    Time
    14:00 - 14:00
    Title
    Swimmer-microrheology
    Location
    Perlman Chemical Sciences Building
    LecturerProf. Shigeyuki Komura
    Tokyo Metropolitan University
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about We discuss the locomotion of a three-sphere microswimmer in ...»
    We discuss the locomotion of a three-sphere microswimmer in a viscoelastic medium and propose a new type of active microrheology.‎ We derive a relation that connects the average swimming velocity and the frequency-dependent viscosity of the surrounding medium.‎
    ‎In this relation, the viscous contribution can exist only when the time-reversal symmetry is broken, whereas the elastic contribution is present only when the structural symmetry of the swimmer is ‎broken.‎ Purcell's scallop theorem breaks down for a three-sphere swimmer in a viscoelastic medium
    Lecture
  • Date:02TuesdayJanuary 201804ThursdayJanuary 2018

    2018 JUSTEN PASSWELL MEMORIAL SYMPOSIUM

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    Time
    08:00 - 08:00
    Location
    The David Lopatie Conference Centre
    Chairperson
    Ofer Yizhar
    Homepage
    Conference
  • Date:02TuesdayJanuary 2018

    Fixing the nitrogen gap - plant strategies of symbiotic dinitrogen fixation across biomes

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    Time
    11:30 - 11:30
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerDr. Efrat Sheffer
    The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Robert H. Smith Faculty of Agriculture, Food and Environment at Rehovot, The Hebrew University of Jerusalem
    Organizer
    Department of Plant and Environmental Sciences
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    Contact
    Lecture
  • Date:02TuesdayJanuary 2018

    Various approaches to online inference - human behavior and theoretical models

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    Time
    12:30 - 12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerDr. Rava Azeredo da Silveira
    Ecole Normale Superieure, Paris, France
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about In natural settings, we make decisions based on streams of p...»
    In natural settings, we make decisions based on streams of partial and noisy information. Arguably, we summarize the perceived information into a probabilistic model of the world, which we can exploit to make decisions. This talk will explore such ‘mental models’ in the context of idealized tasks that can be carried out in the laboratory and modeled quantitatively. The starting point of the talk will be a sequential inference task that probes inference in changing environments, in humans. I will describe the task and an experimental finding, namely, that humans make use of fine differences in temporal statistics when making inferences. While our observations agrees qualitatively with an optimal inference model, the data exhibit biases. What is more, human responses, unlike those of the optimal model, are variable, and this behavioral variability is itself modulated during the inference task. In order to uncover the putative algorithmic framework employed by humans, I will go on to examine a family of models that break away from the optimal model in diverse ways. This investigation will suggest a picture in which humans carry out inference using noisy mental representations. More specifically, rather than representing a whole probability function, human subjects may manipulate probabilities using a (possibly modest) number of samples. The approach just outlined illustrates a range of possible computational structures of sub-optimal inference, but it lacks the appeal of a normative framework. If time permits, I will discuss recent ideas on a normative approach to human inference subject to internal ‘costs’ or ‘drives’, which can explain various biases. While different in its formulation, this approach shares conceptual commonalities with the rational inattention theory and other constrained optimization frameworks in cognitive science.
    Lecture
  • Date:03WednesdayJanuary 2018

    Cancer Immunotherapy: successes and challenges

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    Time
    08:00 - 08:00
    Location
    Dolfi and Lola Ebner Auditorium
    Chairperson
    Dina Preise
    Organizer
    Moross Integrated Cancer Center (MICC)
    Homepage
    Conference
  • Date:03WednesdayJanuary 2018

    Reconstructing temperature and composition histories of sedimentary basins using carbonate clumped-isotope thermometry

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    Time
    10:00 - 10:00
    Location
    Sussman Family Building for Environmental Sciences
    LecturerUri Ryb
    Division of Geological and Planetary Sciences California Institute of Technology
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    AbstractShow full text abstract about Sedimentary basins are commonly viewed as archives of ancien...»
    Sedimentary basins are commonly viewed as archives of ancient depositional environments and geochemical signals measured in these basins are frequently interpreted as proxies for ancient Earth-surface environments. However, in the course of the sedimentary basins life-cycle, sedimentary rocks can undergo alteration in diagenetic, epigenetic and metamorphic environments. When put in the correct context, these altered geochemical records are valuable sources of information that reflect the complex thermal, compositional, and deformational histories experienced by the sedimentary rocks. Additionally these measurements can serve as key observations in the study of the interactions among the Earth’s surface and internal processes.
    In the talk, I will demonstrate how carbonate clumped isotope thermometry (a relatively new temperature-proxy) can be used to study the thermal history of the Colorado Plateau (southwestern N. America), and constrain the oxygen isotope composition of the Phanerozoic Ocean. Clumped and single isotope compositions of calcite and dolomite minerals collected from the Paleozoic sedimentary sequence at the Grand Canyon are consistent with isotopic alteration through open-system recrystallization and/or solid-state isotopic reordering at elevated burial temperatures. By comparing these values with modeled predictions of isotopic signal alteration, we constrain the peak burial temperatures and thermal gradient, and infer the total overburden and exhumation above the top Paleozoic datum at the Colorado Plateau. We also use our data to back-calculate the oxygen isotope composition of dolomite parental water and our results indicate that the oxygen isotope composition of seawater has remained stable throughout the Phanerozoic. This stability suggests that the fluxes of globally averaged oxygen isotope exchange, associated with weathering and hydrothermal alteration reactions, have remained proportional through time. This observation is consistent with the hypothesis that a steady-state balance exists between seafloor hydrothermal activity and surface weathering.
    Lecture
  • Date:03WednesdayJanuary 2018

    G-INCPM Special Seminar - Dr. Yifat Merbl, Dept. of Immunology, Weizmann - "A Ubiquitin-Dependent Mechanism of Proteostasis Control"

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    Time
    14:00 - 15:15
    Location
    Nancy and Stephen Grand Israel National Center for Personalized Medicine
    LecturerProf. Yifat Merbl
    Dept. of Immunology, Weizmann
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Primary focus has been given to the endoplasmic reticulum (E...»
    Primary focus has been given to the endoplasmic reticulum (ER) in the context of quality control of misfolded or aberrant proteins. Although passage from the ER through the Golgi is mandatory for endomembrane and secreted proteins, the Golgi has mainly been studied in the context of its role as a packaging and sorting organelle, and as a site of protein glycomodification. Here I will describe the discovery of a Golgi ApparatusRelated Degradation (GARD) quality control mechanism, which constitutes a novel and important checkpoint in the secretory pathway. Our findings may have significant implications on proteostasis regulation in health and disease.
    Lecture
  • Date:04ThursdayJanuary 2018

    “To see beyond the dot: recent advances in Imaging Flow Cytometry”

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    Time
    09:00 - 10:00
    Location
    Max and Lillian Candiotty Building
    LecturerDr. Ziv Porat
    Flow Cytometry unit
    Organizer
    Department of Life Sciences Core Facilities
    Contact
    Lecture

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