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February 21, 2016
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Date:20TuesdayApril 2021Lecture
From light-harvesting to assembly: Modularity and heterogeneity in photosynthetic antenna systems
More information Time 15:00 - 16:00Title Guest Seminar via ZoomLocation https://weizmann.zoom.us/j/99097904761?pwd=MitYaVJjL0Y4OFU3NWRVeCtDNkkyZz09 Password 247214Lecturer Dr. Hila Toporik
School of Molecular Sciences/The Biodesign Institute, The Center for Applied Structural Discovery, Arizona State UniversityOrganizer Department of Plant and Environmental SciencesContact -
Date:22ThursdayApril 2021Colloquia
Atmospheric Dynamics on Jupiter: New Results from the Juno Mission
More information Time 11:15 - 12:30Location https://weizmann.zoom.us/j/94477142638?pwd=aWNlZGVzNmdJdnJVZVNZUi9sZ0VBZz09Lecturer Prof. Yohai Kaspi
WISOrganizer Faculty of PhysicsContact Abstract Show full text abstract about NASA's Juno Mission is now completing its 5 year nomina...» NASA's Juno Mission is now completing its 5 year nominal mission around Jupiter, orbiting the planet in an eccentric polar-orbit every 53 days. One of the prime mission objectives is better understanding the atmospheric dynamics through gravitational, microwave, infrared and magnetic measurements. In this talk, we will focus on three new results explaining different aspects of the dynamics on Jupiter. First, infrared imaging data revealed that Jupiter’s poles are surrounded by 5 cyclones around the North Pole and 8 cyclones around the South Pole. We explain the location, size and stability of these circumpolar cyclones based on vorticity dynamics. Second, using microwave data, revealing Jupiter’s deep ammonia abundance structure, we show that Jupiter has 8 meridional circulation cells in each hemisphere. These cells resemble in their governing physics Earth's midlatitude Ferrel cells, and relate to the observed red and white belts and zones at Jupiter’s cloud-level. Finally, using Juno’s gravity measurements we constrain the depth of Jupiter’s east-west jet-streams, and the depth (mass) of the most iconic vortex in the Solar system — Jupiter’s Great Red Spot. Overall, this unique multiple instrument dataset allows now explaining the governing physics of several outstanding aspects of Jupiter’s internal and atmospheric dynamics. We will also compare the dynamics to those of Saturn, generalizing some of the this new understanding. -
Date:22ThursdayApril 2021Lecture
Therapeutic Exploitation of Metabolic Vulnerabilities of Cancer
More information Time 14:00 - 15:00Lecturer Prof. Eyal Gottlieb
Ruth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of TechnologyOrganizer Dwek Institute for Cancer Therapy ResearchContact -
Date:25SundayApril 2021Lecture
“Elastic-mediated interactions between cells”
More information Time 11:00 - 12:00Lecturer Prof. Shelly Tzlil
Faculty of Mechanical Engineering, TechnionOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Zoom Link: https://weizmann.zoom.us/j/97324532197?pwd=MGoxSG...» Zoom Link: https://weizmann.zoom.us/j/97324532197?pwd=MGoxSGhJODNWQ2ZGT1p4elJjMG9lZz09
Cell-cell communication is essential for growth, development and function. Cells can communicate mechanically by responding to mechanical deformations generated by their neighbors in the extracellular matrix (ECM). The ECM is a non-linear viscoelastic material and therefore mechanical communication is expected to be frequency-dependent. In my talk, I will describe our work on the characteristics and implications of mechanical communication over the ECM. -
Date:25SundayApril 2021Lecture
Seminar for Thesis defense of Gat Krieger
More information Time 13:30 - 14:30Title Evolution of gene regulation in yeast through changes in transcription factor binding and gene expressionLocation https://weizmann.zoom.us/j/93751101380?pwd=QWJRQzVSZXVOWitiRWdJU1ZMSlFSQT09Lecturer Gat Krieger Organizer Department of Molecular GeneticsContact -
Date:26MondayApril 2021Lecture
Physics-guided machine-learning parameterizations of subgrid processes for climate modeling
More information Time 14:00 - 14:00Location https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09Lecturer Janni Yuval
Earth, Atmospheric and Planetary Sciences MIT school of ScienceOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about Global climate models represent small-scale processes, such ...» Global climate models represent small-scale processes, such as clouds and convection, using subgrid models known as parameterizations. Traditional parameterizations are usually based on simplified physical models, and inaccuracies in these parameterizations are a main cause for the large uncertainty in climate projections. One alternative to traditional parameterizations is to use machine learning to learn new parameterizations which are data driven. However, machine-learning parameterizations might violate physical principles and often lead to instabilities when coupled to an atmospheric model. I will show how machine learning algorithms, such as neural networks and random forests, can be used to learn new parameterizations from the output of a three-dimensional high-resolution atmospheric model, while obeying physical constraints such as energy conservation. Implementing these parameterizations in the atmospheric model at coarse resolution leads to stable simulations that replicate the climate of the high-resolution simulation, and capture important statistics such as precipitation extremes. I will also discuss how machine-learning parameterizations can give further insights into the parameterization problem. Specifically, I will show that failures of machine-learning parameterizations can be used to better understand the relationship between large-scale fields and subgrid processes. -
Date:27TuesdayApril 2021Lecture
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
More information Time 10:00 - 11:00Location Via zoom:https://weizmann.zoom.us/j/95881429481?pwd=VkxwUmg1Z2ErZmhpZDJqMTZwellGZz09Lecturer Oshrat Galibov-Levi
Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about In the colon, long-term exposure to chronic inflammation dri...» In the colon, long-term exposure to chronic inflammation drives colitis-associated colon cancer (CAC). However, molecular understanding of how this occurs is still lacking. Within the tumor, cancer cells are surrounded by a variety of non-malignant cells and by the extracellular matrix (ECM), which together compose the tumor microenvironment (TME), which is essential for tumor homeostasis and progression. While the cancer cells are highly mutated, the stromal cells are genomically stable. Master regulator heat shock factor 1 (HSF1) was shown to play an important part in the transcriptional reprogramming of the TME. By using proteomic and advanced methods of microscopy and image analysis we show that HSF1-dependent ECM remodeling plays a crucial role in mediating inflammation-driven colon cancer.
/j/95881429481?pwd=VkxwUmg1Z2ErZmhpZDJqMTZwellGZz09 -
Date:27TuesdayApril 2021Lecture
Deposition of Gypsum Deltas at the Holocene Dead Sea by outsalting and paleoclimatic insights
More information Time 10:00 - 11:00Location https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09Lecturer Nurit Weber
Department of Earth and Planetary Sciences Weizmann Institute of SciencesOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about The rapid retreat of the Dead Sea during the past decades le...» The rapid retreat of the Dead Sea during the past decades led the exposure of unique structures of massive gypsum and aragonite crusts: large capes pointing towards the open lake (termed here “gypsum deltas”) and numerous small gypsum mounds scattered on the lake’s exposed shores. Geological field relations, 14C and 34S measurements and thermodynamic calculations provide evidence that the gypsum deltas and the mounds were formed during time-intervals of low lake stands (~420±10 m below mean sea level), when sulfate-rich Ca-chloride brines discharged from the coastal aquifer via saline springs, mixed with the Dead Sea brine and precipitated the gypsum. This mixing process describes a mechanism of “gypsum outsalting”, which is completely different from the conventional view of gypsum as a product of evaporative deposition.
Condition for enhanced saline springs discharge and “gypsum outsalting” occurred in the mid to late Holocene period (~ 6.6 to 0.6 ka), and were mainly intensive at the latest stages of regional aridity cycles when lake level was still low and the Dead Sea salinity was at its highest. The ages of formation of the gypsum structures coincide with times of North Atlantic cooling events and grand solar minima suggesting a direct impact of the latter on the Dead Sea hydrology and high sensitivity of the regional hydrology (controlling lake level) to global solar-related events. The frequency of appearance of the gypsum structures seems to follow the Hallstat Cycle that approached minimum at ~3000 2000 years ago.
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Date:27TuesdayApril 2021Lecture
New Insights on Bioaggregates and the Aquatic N Cycle
More information Time 11:30 - 12:30Title Hybrid Guest Seminar-Room 690C, floor6!Location https://weizmann.zoom.us/j/94920680518?pwd=MDhOVUZsQWRaMGZSYndIME5lZGtRdz09 Password 151190Lecturer Dr. Edo Bar-Zeev
Roy J Zuckerberg Career Development Chair for Water Research, Department of Environmental Hydrology & Microbiology, Zuckerberg Institute for Water Research (ZIWR), The Jacob Blaustein Institutes for Desert Research (BIDR), Ben-Gurion University of the NegevOrganizer Department of Plant and Environmental SciencesContact -
Date:27TuesdayApril 2021Lecture
Neural correlates of future weight loss reveal a possible role for brain-gastric interactions
More information Time 12:30 - 13:30Lecturer Prof. Galia Avidan
Dept of Psychology Ben Gurion University of the NegevOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Lifestyle dietary interventions are an essential practice in...» Lifestyle dietary interventions are an essential practice in treating obesity, hence neural factors that may assist in predicting individual treatment success are of great significance. Here, in a prospective, open-label, three arms study, we examined the correlation between brain resting-state functional connectivity measured at baseline and weight loss following 6 months of lifestyle intervention in 92 overweight participants. We report a robust subnetwork composed mainly of sensory and motor cortical regions, whose edges correlated with future weight loss. This effect was found regardless of intervention group. Importantly, this main finding was further corroborated using a stringent connectivity-based prediction model assessed with cross-validation thus attesting to its robustness. The engagement of senso-motor regions in this subnetwork is consistent with the over-sensitivity to food cues theory of weight regulation. Finally, we tested an additional hypothesis regarding the role of brain-gastric interaction in this subnetwork, considering recent findings of a cortical network synchronized with gastric activity. Accordingly, we found a significant spatial overlap with the subnetwork reported in the present study. Moreover, power in the gastric basal electric frequency within our reported subnetwork negatively correlated with future weight loss. This finding was specific to the weight loss related subnetwork and to the gastric basal frequency. These findings should be further corroborated by combining direct recordings of gastric activity in future studies. Taken together, these intriguing results may have important implications for our understanding of the etiology of obesity and the mechanism of response to dietary intervention as well as to interoceptive perception.
Zoom link to join:
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
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Date:28WednesdayApril 2021Lecture
Spotlight on Science Lecture - Travelling The SILC Road: The Non-Coding Path to Nerve Regeneration
More information Time 11:00 - 12:00Title https://weizmann.zoom.us/j/99718325744?pwd=QWJVNGw5cTA5SU1Ed1VVZnViZ0lUQT09 Password: 193088Location https://weizmann.zoom.us/j/99718325744?pwd=QWJVNGw5cTA5SU1Ed1VVZnViZ0lUQT09Lecturer Dr. Rotem Ben-Tov-Perry
Department of Biological RegulationOrganizer Department of Life Sciences Core FacilitiesContact Abstract Show full text abstract about Travelling The SILC Road: The Non-Coding Path to Nerve Rege...» Travelling The SILC Road:
The Non-Coding Path to Nerve Regeneration -
Date:02SundayMay 202103MondayMay 2021International Board
Executive Board and committees meetings 2021
More information Time All dayLocation Digital platformContact -
Date:03MondayMay 2021Colloquia
Magnetic control over chemical bonds in atomic-wires and molecular junctions
More information Time 11:00 - 12:00Location https://weizmann.zoom.us/j/98063488104?pwd=N3VqTC9sU1A4RHVDZ1dhOGVxbU1iUT09Lecturer Prof. Oren Tal
Department of Chemical & Biological Physics, WISOrganizer Faculty of ChemistryContact Abstract Show full text abstract about Controlling the properties of chemical bonds by an external ...» Controlling the properties of chemical bonds by an external stimulus is a central goal in chemistry. At the level of individual bonds, such control was achieved using light, current, electrochemical potential and electric field. In my talk, I will show that the size and direction of applied magnetic fields can affect bond stability, interatomic distance, and bond-formation probability. This behavior is demonstrated in a variety of atomic wires and single-molecule junctions. The revealed magneto-structural phenomena show that the influence of magnetic interactions on chemical bonds can be dramatic in nanoscale systems. -
Date:03MondayMay 2021Lecture
IMM Guest seminar- Dr. Michael Brusilovsky, will lecture on "Unlocking the mechanisms of innate-immune sensory systems."
More information Time 13:00 - 14:00Lecturer Dr. Michael Brusilovsky Organizer Department of Systems ImmunologyContact -
Date:03MondayMay 2021Lecture
Cooperative Carbon Capture in Metal–Organic Frameworks
More information Time 18:00 - 19:00Title SAERI - Sustainability and Energy Research Initiative seminar seriesLocation via zoomLecturer Prof. Jeffrey R. Long
Departments of Chemistry and Chemical & Biomolecular Engineering,University of California, Berkeley, USAOrganizer Weizmann School of ScienceContact -
Date:04TuesdayMay 2021Lecture
What causes the leakiness of the North Atlantic Deep Western Boundary Current?
More information Time 10:00 - 10:00Location https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09Lecturer Aviv Solodoch
Department of Atmospheric and Oceanic Sciences UCLAOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about The Atlantic Meridional Overturning Circulation (AMOC) is a ...» The Atlantic Meridional Overturning Circulation (AMOC) is a circulation pattern of great climatic importance. Its northward heat flux at the upper water column moderates European winter climate, and its descending branch captures atmospheric CO2 into the deep ocean, hence buffering the anthropogenically induced rise in global temperature.
The Deep Western Boundary Current (DWBC) has classically been considered to be the main AMOC conduit southward at depth. However, tracer data have shown in recent decades that the DWBC "leaks" most of its material to the ocean interior in a small region of the North Atlantic, and that this leaked material continues southward in different, complex routes. These pathways and their causes are still little-explored and not well understood.
In this talk I will present analysis of the DWBC leakiness properties and dynamics, based on existing datasets of passively drifting floats, a new high resolution regional numerical model, and theoretical analysis. Several alternative mechanisms of leakiness are considered, and a novel finding is that a leading cause for the leakiness is inertial separation of the current from the seafloor, near underwater capes. The role of eddies and their interaction with the separation process is investigated as well. Implications for the robustness of the deep AMOC pathways are discussed.
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Date:04TuesdayMay 2021Lecture
Dissection of floral transition by single meristem transcriptomes at high temporal resolution
More information Time 11:30 - 12:30Title Dept. Seminar via ZoomLocation https://weizmann.zoom.us/j/94920680518?pwd=MDhOVUZsQWRaMGZSYndIME5lZGtRdz09 Password 151190Lecturer Zohar Meir
PhD student, co-advised by Prof. Amos Tanay, Faculty of Mathematics & Computer Science and Prof. Yuval Eshed, Department of Plant and Environmental SciencesOrganizer Department of Plant and Environmental SciencesContact -
Date:04TuesdayMay 2021Lecture
The Vagus Nerve and Physiology of Reward and Digestion
More information Time 15:00 - 15:00Lecturer Prof. Ivan E de Araujo
Neuroscience Dept, Diabetes, Obesity and Metabolism Institute Icahn School of Medicine at Mount SinaiOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The presentation will discuss recent evidence supporting a...»
The presentation will discuss recent evidence supporting a role for the gut-brain axis in controlling brain circuits involved in reward. It will be argued that sensory neurons of vagus nerve function as reward neurons. Via defined brainstem targets, vagal signals dopaminergic brain reward circuits in midbrain. The mapping of these circuits opens a window into how signals generated by internal body organs give rise to motivated and emotional behaviors.
Zoom link to join-
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
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Date:06ThursdayMay 2021Lecture
Examples of method development for targeted metabolic analysis using LC-MS
More information Time 09:00 - 09:00Location via ZOOMLecturer Dr. Alexander Brandis
Targeted Metabolomics UnitOrganizer Department of Life Sciences Core FacilitiesHomepage Contact -
Date:06ThursdayMay 2021Lecture
Zoom Lecture: “NMR of RNA: dynamics or in-cells”
More information Time 09:15 - 10:15Lecturer Prof. Katja Petzold
Dept. of Medical Biochemistry and Biophysics, Karolinska Institute, StockholmOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Zoom Lecture: https://weizmann.zoom.us/j/98819686427?pwd=...» Zoom Lecture: https://weizmann.zoom.us/j/98819686427?pwd=algvMEJUNHdvaFppNS9xVzlTUkhYQT09
Passcode: 551107
Many functions of RNA depend on rearrangements in secondary structure that are triggered by external factors, such as protein or small molecule binding. These transitions can feature on one hand localized structural changes in base-pairs or can be presented by a change in chemical identity of e.g. a nucleo-base tautomer. We use and develop R1ρ-relaxation-dispersion NMR methods for characterizing transient structures of RNA that exist in low abundance (populations
