Pages
September 01, 2016
-
Date:17SundayMarch 2019Lecture
Pattern restoration for wound healing in plants
More information Time 10:00 - 10:00Title Special Guest SeminarLocation Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Jiri Friml
Institute of Science and Technology Austria (IST Austria)Organizer Department of Plant and Environmental SciencesHomepage Contact -
Date:17SundayMarch 2019Lecture
Reductionist vs. Emergence-based approaches to the study of complex systems: Examples from cloud systems
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Graham Feingold
NOAAOrganizer Department of Earth and Planetary SciencesContact -
Date:17SundayMarch 2019Lecture
Phase separation in multicomponent liquid mixtures
More information Time 13:00 - 13:00Location Edna and K.B. Weissman Building of Physical SciencesLecturer Andrej Kosmrlj
PrincetonOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about Multicomponent systems are ubiquitous in nature and industry...» Multicomponent systems are ubiquitous in nature and industry. While the physics of binary and ternary liquid mixtures is well-understood, the thermodynamic and kinetic properties of N-component mixtures with N>3 have remained relatively unexplored. Inspired by recent examples of intracellular phase separation, we investigate equilibrium phase behavior and morphology of N-component liquid mixtures within the Flory-Huggins theory of regular solutions. In order to determine the number of coexisting phases and their compositions, we developed a new algorithm for constructing complete phase diagrams, based on numerical convexification of the discretized free energy landscape. Together with a Cahn-Hilliard approach for kinetics, we employ this method to study mixtures with N=4 and 5 components. In this talk I will discuss both the coarsening behavior of such systems, as well as the resulting morphologies in 3D. I will also mention how the number of coexisting phases and their compositions can be extracted with Principal Component Analysis (PCA) and K-Means clustering algorithms. Finally, I will discuss how one can reverse engineer the interaction parameters and volume fractions of components in order to achieve a range of desired packing structures, such as nested "Russian dolls" and encapsulated Janus droplets. -
Date:18MondayMarch 2019Lecture
The clever way Vibrio invades, forming a protective, intracellular niche in host cells.
More information Time 10:00 - 11:00Title Host-pathogen interactions clubLocation Max and Lillian Candiotty BuildingLecturer Prof. Kim Orth
UT Southwestern Medical Center, Dallas, TexasOrganizer Department of Immunology and Regenerative BiologyContact -
Date:18MondayMarch 2019Colloquia
"Smart Interfacial Materials: from Super-Wettability to Binary Cooperative Complementary Systems"
More information Time 11:00 - 12:30Location Camelia Botnar BuildingLecturer Prof. Lei Jiang
Beihang UniversityOrganizer Faculty of ChemistryContact -
Date:18MondayMarch 2019Lecture
“LAP and LANDO: Noncanonical functions of autophagy proteins in anti-cancer immunity and Alzheimer's Disease”
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Dr. Douglas R. Green
Chair, Dept. of Immunology St. Jude Children's Research Hospital Memphis, Tennessee, USAOrganizer Department of Molecular Cell BiologyContact -
Date:18MondayMarch 2019Lecture
Effects of Stochasticity and non-locality on a model of aggregation-fragmentation for Saturn rings
More information Time 14:15 - 14:15Location Edna and K.B. Weissman Building of Physical SciencesLecturer Bijoy Daga
Institute of Mathematical Sciences, Chennai, IndiaOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about Saturn rings are composed of water-ice particles and traces ...» Saturn rings are composed of water-ice particles and traces of rocky materials whose sizes may vary from micro meters to a few meters. A model that describes the observed size distribution considers aggregation and fragmentation of ring particles upon collision and the distribution can be calculated analytically by solving the steady state Smoluchowski equation.
In writing down the deterministic Smoluchowski equation, it is assumed that the total mass is infinite. We try to understand the behavior of the system when the total mass is finite and the effects of Stochasticity becomes important.
Further, it has been observed that the steady state in these systems becomes unstable and shows oscillations for non-local reaction Kernels. We will also discuss the role of non-locality for the case of finite total mass when Stochasticity becomes relevant and see whether oscillations would survive or not.
-
Date:19TuesdayMarch 2019Lecture
Degron discovery: Hunt for the elusive dark matter of protein quality control
More information Time 14:00 - 15:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Tommer Ravid
HUJIOrganizer Department of Chemical and Structural BiologyContact -
Date:19TuesdayMarch 2019Lecture
Department of Molecular Genetics seminar for thesis defense
More information Time 14:00 - 15:00Title “Proliferation Limitations in the Budding Yeast”Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Eyal Metzl Raz Organizer Department of Molecular GeneticsContact -
Date:20WednesdayMarch 2019Lecture
Developmental Club Series 2018-2019
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Eran Hornstein Organizer Department of Molecular GeneticsContact -
Date:20WednesdayMarch 2019Lecture
Developmental Club Series 2018-2019
More information Time 10:00 - 11:00Title “Stepwise assembly of dendritic arbors”Location Camelia Botnar BuildingLecturer Hannes Buelow
Albert Einstein College of Medicine, NYOrganizer Department of Molecular GeneticsContact -
Date:21ThursdayMarch 2019Lecture
Exosomal transmission between macrophages and cancer cells: new insights to sroma-mediated drug resistance
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Ziv Gil Organizer Department of Immunology and Regenerative BiologyContact -
Date:24SundayMarch 2019Lecture
Multiphase Chemistry of Organic Aerosols and Reactive Oxygen Species in the Atmosphere
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Manabu Shiraiwa
UCIOrganizer Department of Earth and Planetary SciencesContact -
Date:24SundayMarch 2019Lecture
Interfacial rheology - why, what, and how
More information Time 11:00 - 12:00Location Perlman Chemical Sciences BuildingLecturer Prof. Moshe Gottlieb
Dept of Chemical Engineering, Ben Gurion UniversityOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about The idea that complex liquid-air interfaces laden with sur...»
The idea that complex liquid-air interfaces laden with surfactants, colloids, or polymer molecules, possess rheological properties that differ from those of the bulk sub-phase has been suggested 150 years ago. Yet, even today we are still struggling with the means to properly measure these properties. In this talk we will first explore the reasons to worry at all about the properties of the interface, examine some of the consequences of interfacial rheology, and revisit a century old technique - the unjustifiably named “Langmuir trough”, pointing out some experimental peculiarities.
-
Date:25MondayMarch 201926TuesdayMarch 2019Conference
Big Data in Education
More information Time 08:00 - 08:00Chairperson Giora Alexandron -
Date:25MondayMarch 2019Lecture
Guest seminar- Dr. Gunnar Dittmar will lecture on "“Large-scale mapping of PTM-induced interactome changes.”
More information Time 11:00 - 12:00Location Camelia Botnar BuildingLecturer Dr. Gunnar Dittmar
Luxembourg Institute of Health, Quantitative Biology unit Proteomics of cellular signaling.Organizer Department of Systems ImmunologyContact -
Date:25MondayMarch 2019Lecture
IMM Guest seminar- Prof.Yuval Shaked will lecture on "Therapy-induced a phenotype and functional switch in cells at the tumor microenvironment in response to therapy dictates tumor fate.""
More information Time 13:00 - 14:00Location Wolfson Building for Biological ResearchLecturer Prof. Yuval Shaked
Cell Biology and Cancer Science Technion Integrated Cancer Center Rappaport Faculty of Medicine Technion - Israel Institute of Technology .Organizer Department of Systems ImmunologyContact -
Date:25MondayMarch 2019Lecture
Hyperuniformity of driven suspensions
More information Time 14:15 - 14:15Location Edna and K.B. Weissman Building of Physical SciencesLecturer Haim Diamant
Chemistry, TAUOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about An arrangement of particles is said to be "hyperuniform...» An arrangement of particles is said to be "hyperuniform" if its density fluctuations over large distances are strongly suppressed relative to a random configuration. Crystals, for example, are hyperuniform. Recently, several disordered materials have been found to be hyperuniform. Examples are sheared suspensions and emulsions, and, possibly, random close packings of particles. We show that externally driven particles in a liquid suspension (as in sedimentation, for example) self-organize hyperuniformly in certain directions relative to the external force. This dynamic hyperuniformity arises from the long-range coupling, induced by the force and carried by the fluid, between the concentration of particles and their velocity field. We obtain the general requirements, which the coupling should satisfy in order for this phenomenon to
occur. Under other conditions (e.g., for certain particle shapes), the
coupling can lead to the opposite effect -- enhancement of density
fluctuations and instability. We confirm these analytical results in a
simple two-dimensional simulation.
-
Date:26TuesdayMarch 2019Lecture
Long noncoding RNAs in neurogenesis and neuroregeneration
More information Time 09:00 - 10:00Title Stem Cells, Regeneration and Aging SeminarLocation Max and Lillian Candiotty BuildingLecturer To be announced Organizer Department of Immunology and Regenerative BiologyContact -
Date:26TuesdayMarch 2019Lecture
The mitochondrial protein Efhd1 is regulated by Liver Kinase B1 and is required for neuronal development
More information Time 10:00 - 10:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Valeria Ulisse
Department of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about During development, neurons need to couple their robust axon...» During development, neurons need to couple their robust axonal growth with their energetic balance. The mechanisms that regulate this coupling are largely unknown. Here we show that sensory neurons that lack Liver Kinase B1 (LKB1), a master regulator of energy homeostasis, exhibit reduced axonal growth and branching. Biochemical analysis of these LKB1 KO neurons revealed metabolic irregularities, manifested by axonal reduction in ATP levels. Genomic analysis uncovered downregulation in Efhd1 (EF-Hand Domain Family Member D1), a mitochondrial Ca2+-binding protein in the LKB1 KO sensory neurons. Strikingly, genetic ablation of Efhd1 caused a decrease in the axonal ATP levels and activation of the AMPK (AMP-activated protein kinase) pathway in sensory neurons. Moreover, we detected shortened mitochondria at the axonal growth cones and activation of the mitophagy regulator ULK (Unc-51 like autophagy activating kinase). Suggesting that Efhd1 is an important regulator of the axonal mitochondria. Notably, these metabolic dysfunctions were manifested by reduced axonal growth in vitro, and axonal branching defects and enhanced neuronal death in vivo. Overall, our work uncovers a new metabolic pathway that couples mitochondrial and axonal growth through Efhd1.