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February 01, 2019
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Date:12TuesdayMarch 2019Lecture
Towards Increased Complexity in Dynamic Covalent Systems and Metal-Organic Cages
More information Time 11:00 - 12:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Anna McConnell
Otto-Diels-Institut für Organische Chemie Christian-Albrechts-Universität zu KielOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Anna McConnell, Otto Diels Institute of Organic Chemistry, C...» Anna McConnell, Otto Diels Institute of Organic Chemistry, Christian-Albrechts-Universität zu Kiel
The supramolecular toolbox enables the self-assembly of supramolecular architectures from relatively simple building blocks through reversible, weak non-covalent interactions. Supramolecular architectures with increased complexity are appealing targets for not only the synthetic challenge but also for the potential to access new types of chemistry and functionality. Efforts towards increasing the complexity of both the supramolecular architecture and stimuli-responsive behaviour[1] in dynamic covalent and metal-organic cage systems will be presented. In one approach, the post-assembly reduction of achiral iminoboronates gives access to three isomeric products containing two stereogenic centres and two of these products interconvert through unusual lability of the covalent B-N bonds.[2] In another approach, progress towards the development and characterisation of spin-crossover cages[3] with increased complexity will be discussed.
References
[1] A. J. McConnell, C. S. Wood, P. P. Neelakandan, J. R. Nitschke, Chem. Rev. 2015, 115, 7729-7793.
[2] E. N. Keyzer, A. Sava, T. K. Ronson, J. R. Nitschke, A. J. McConnell, Chem. Eur. J. 2018, 24, 12000-12005.
[3] A. J. McConnell, Supramol. Chem. 2018, 30, 858-868.
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Date:12TuesdayMarch 2019Lecture
Dr. Neta Regev-Rudzki - Communication between malaria parasites
More information Time 12:00 - 12:00Title Communication between malaria parasitesLocation Dolfi and Lola Ebner AuditoriumLecturer Prof. Neta Regev-Rudzki Organizer Communications and Spokesperson DepartmentHomepage Contact -
Date:12TuesdayMarch 2019Lecture
What makes tetra-ubiquitin a preferred signal for targeting proteins to the proteasome?
More information Time 14:00 - 15:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Michael Glickman
TechnionOrganizer Department of Chemical and Structural BiologyContact -
Date:12TuesdayMarch 2019Lecture
The odor identity puzzle: How odor information can be shared across hemispheres if there are no cortical odor maps?
More information Time 14:00 - 14:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Rafi Haddad
The Gonda Multidisciplinary Brain Research Center Bar-Ilan UniversityOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Sensory input reaching the brain from bilateral and offset c...» Sensory input reaching the brain from bilateral and offset channels is nonetheless perceived as unified. This unity could be explained by simultaneous projections to both hemispheres, or inter-hemispheric information transfer between sensory cortical maps. Odor input, however, is not topographically organized, nor does it project bilaterally, making olfactory perceptual unity enigmatic. Here we report a circuit that interconnects mirror-symmetric isofunctional output cells between the mouse olfactory bulbs. Connected neurons respond to similar odors from ipsi- and contra-nostrils, whereas unconnected neurons do not respond to odors from the contralateral nostril. This circuit enables sharing of odor information across hemispheres in the absence of a cortical topographical organization, suggesting that olfactory glomerular maps are the equivalent of cortical sensory maps found in other senses. -
Date:13WednesdayMarch 2019Lecture
Developmental Club Series 2018-2019
More information Time 10:00 - 10:00Title “Regulation of cell cycle by nuclear mechanical inputs”Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Talila Volk Organizer Department of Molecular GeneticsContact -
Date:13WednesdayMarch 2019Lecture
The Lab on a Beam: From Learning Physics to Atomic Manipulation in Scanning Transmission Electron Microscopy
More information Time 11:00 - 12:00Location Perlman Chemical Sciences BuildingLecturer Dr. Sergei Kalinin
Institute for Functional Imaging of Materials (IFIM), Oak Ridge National LabOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Atomically-resolved imaging of materials has become the main...» Atomically-resolved imaging of materials has become the mainstay of modern materials science, as enabled by advent of aberration corrected scanning transmission electron microscopy (STEM). However, the wealth of quantitative information contained in the fine details of atomic structure or spectra remains largely unexplored. In this talk, I will present the new opportunities enabled by physics-informed big data and machine learning technologies to extract physical information from static and dynamic STEM images. The deep learning models trained on theoretically simulated images or labeled library data demonstrate extremely high efficiency in extracting atomic coordinates and trajectories, converting massive volumes of statistical and dynamic data into structural descriptors. I further present a method to take advantage of atomic-scale observations of chemical and structural fluctuations and use them to build a generative model (including near-neighbor interactions) that can be used to predict the phase diagram of the system in a finite temperature and composition space. Similar approach is applied to probe the kinetics of solid-state reactions on a single defect level and defect formation in solids via atomic-scale observations. Finally, synergy of deep learning image analytics and real-time feedback further allows harnessing beam-induced atomic and bond dynamics to enable direct atom-by-atom fabrication. Examples of direct atomic motion over mesoscopic distances, engineered doping at selected lattice site, and assembly of multiatomic structures will be demonstrated. These advances position STEM towards transition from purely imaging tool for atomic-scale laboratory of electronic, phonon, and quantum phenomena in atomically-engineered structures. -
Date:13WednesdayMarch 2019Lecture
MM Special Guest Seminar: Hiderou Yoshida, Ph. D., will lecture about "New insights into ER- and Golgi- stress responses."
More information Time 13:00 - 14:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Hiderou Yoshida, Ph. D.
Department of Biochemistry and Molecular Biology University of Hyogo, JapanOrganizer Department of Systems ImmunologyContact -
Date:14ThursdayMarch 2019Conference
EPScon 2019
More information Time 08:00 - 08:00Location The David Lopatie Conference CentreChairperson Madi AmerOrganizer Department of Earth and Planetary SciencesHomepage -
Date:14ThursdayMarch 2019Colloquia
Silicon Day: Plant Minerals in Modern and Archaeological Environments
More information Time 09:00 - 12:00Title If you intend to attend, please let us know in advanced.Location Faculty of Agriculture, Cabin – 8Lecturer Rivka Elbaum, Nerya Zexer, Evgenia Vaganov, Steve Weiner, Rosa M. Albert, Oriol Andreu, and Filipe Natalio., Prof. Elisabetta Boaretto Organizer Academic Educational ResearchContact -
Date:14ThursdayMarch 2019Lecture
Nonlinear light-matter interaction: from superconducting qubits to spins in diamond
More information Time 10:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Prof. Eyal Buks
Faculty of Electrical Engineering, TechnionOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about The talk is devoted to the study of the light-matter inter...»
The talk is devoted to the study of the light-matter interaction in the nonlinear regime using three different cavity quantum electrodynamics (CQED) systems. The matter under study is a Josephson flux qubit in the first experiment [1], a spin ensemble of diphenylpicrylhydrazyl (DPPH) molecules in the second one, and different spin ensembles in a diamond lattice in the third one [3]. In all three experiments the matter under study interact with photons (light) confined in a superconducting microwave resonator (cavity). A variety of nonlinear effects are explored, including super-harmonic resonances, multi-photon resonances, effective cavity heating and cooling and motional narrowing induced by quantum-jumps. The effect of nonlinearity on spin detection sensitivity will be discussed.
1. Eyal Buks, Chunqing Deng, Jean-Luc F.X. Orgazzi, Martin Otto and Adrian Lupascu, Phys. Rev. A 94, 033807 (2016).
2. Hui Wang, Sergei Masis, Roei Levi, Oleg Shtempluk and Eyal Buks, Phys. Rev. A 95, 053853 (2017).
3. Nir Alfasi, Sergei Masis, Roni Winik, Demitry Farfurnik, Oleg Shtempluck, Nir Bar-Gill and Eyal Buks, Phys. Rev. A 97 (2018).
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Date:14ThursdayMarch 2019Lecture
A linear multisite phosphorylation code controls cell cycle progression
More information Time 11:00 - 12:00Location Max and Lillian Candiotty BuildingLecturer Prof. Mart Loog Organizer Department of Immunology and Regenerative BiologyContact -
Date:14ThursdayMarch 2019Lecture
Genetic programs that differentiate tomato axillary shoots from their primary shoot progenitor
More information Time 11:00 - 11:00Title PhD thesis defenseLocation Nella and Leon Benoziyo Building for Biological SciencesLecturer Anna Goren
Prof. Yuval Eshed's lab, Department of Plant and Environmental SciencesOrganizer Department of Plant and Environmental SciencesContact -
Date:14ThursdayMarch 2019Colloquia
Plasmas at the extreme
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Luis O. Silva
GoLP/IPFN and Phys Dep, Instituto Superior Tecnico, Universidade de Lisboa, PortugalOrganizer Faculty of PhysicsContact Abstract Show full text abstract about Many astrophysical and laboratory scenarios share common und...» Many astrophysical and laboratory scenarios share common underlying microphysics, and collective plasma effects associated with intense fields can have direct consequences on the plasma dynamics. These mechanisms, also involving QED effects, are highly nonlinear and multi scale, and require a combination of theory and large scale numerical simulations. The main challenges to address these scenarios will be discussed, as well as recent progresses triggered by large scale simulations of compact objects or of conditions in their vicinity, and developments on multi dimensional laser/beam plasma interactions in the presence of fields close to the critical Schwinger field, as expected in the most intense lasers now being built or in the most advanced particle accelerators. The connections between these scenarios will be discussed, emphasising the interplay between collective plasma dynamics and QED processes. Examples from both laboratory and astrophysical conditions will be provided.
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Date:14ThursdayMarch 2019Lecture
Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer
More information Time 14:00 - 15:00Title Special Guest SeminarLocation Max and Lillian Candiotty BuildingLecturer Prof. Shulamit Katzav-Shapira
Developmental Biology and Cancer Research, School of Medicine, Hebrew University JerusalemOrganizer Department of Immunology and Regenerative BiologyContact -
Date:17SundayMarch 201921ThursdayMarch 2019Conference
Brain Malformations: A Roadmap for Future Research
More information Time 08:00 - 08:00Location The David Lopatie Conference CentreChairperson Orly ReinerHomepage -
Date:17SundayMarch 2019Lecture
Department of Molecular Genetics seminar for thesis defense
More information Time 09:00 - 10:00Title “Identification of the IDPs sequence motifs conferring targeting to the 20S proteasome-PSMA3 and p21 model”Location Belfer room 325Lecturer Marianna Riutin Organizer Department of Molecular GeneticsContact -
Date:17SundayMarch 2019Lecture
Pattern restoration for wound healing in plants
More information Time 10:00 - 10:00Title Special Guest SeminarLocation Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Jiri Friml
Institute of Science and Technology Austria (IST Austria)Organizer Department of Plant and Environmental SciencesHomepage Contact -
Date:17SundayMarch 2019Lecture
Reductionist vs. Emergence-based approaches to the study of complex systems: Examples from cloud systems
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Graham Feingold
NOAAOrganizer Department of Earth and Planetary SciencesContact -
Date:17SundayMarch 2019Lecture
Phase separation in multicomponent liquid mixtures
More information Time 13:00 - 13:00Location Edna and K.B. Weissman Building of Physical SciencesLecturer Andrej Kosmrlj
PrincetonOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about Multicomponent systems are ubiquitous in nature and industry...» Multicomponent systems are ubiquitous in nature and industry. While the physics of binary and ternary liquid mixtures is well-understood, the thermodynamic and kinetic properties of N-component mixtures with N>3 have remained relatively unexplored. Inspired by recent examples of intracellular phase separation, we investigate equilibrium phase behavior and morphology of N-component liquid mixtures within the Flory-Huggins theory of regular solutions. In order to determine the number of coexisting phases and their compositions, we developed a new algorithm for constructing complete phase diagrams, based on numerical convexification of the discretized free energy landscape. Together with a Cahn-Hilliard approach for kinetics, we employ this method to study mixtures with N=4 and 5 components. In this talk I will discuss both the coarsening behavior of such systems, as well as the resulting morphologies in 3D. I will also mention how the number of coexisting phases and their compositions can be extracted with Principal Component Analysis (PCA) and K-Means clustering algorithms. Finally, I will discuss how one can reverse engineer the interaction parameters and volume fractions of components in order to achieve a range of desired packing structures, such as nested "Russian dolls" and encapsulated Janus droplets. -
Date:18MondayMarch 2019Lecture
The clever way Vibrio invades, forming a protective, intracellular niche in host cells.
More information Time 10:00 - 11:00Title Host-pathogen interactions clubLocation Max and Lillian Candiotty BuildingLecturer Prof. Kim Orth
UT Southwestern Medical Center, Dallas, TexasOrganizer Department of Immunology and Regenerative BiologyContact
