• Picture of Prof. Yardena Samuels

    Prof. Yardena Samuels

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    Synthetic lethal interaction network of melanoma
    Identification of melanoma hub interactomes
    CRISPR screens to reveal driver gene interactions and drug resistance genes
    Decipher the immuno-genetic interactions between melanoma and T cells
    HLA peptidome analysis of metastatic melanoma lesions

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  • Picture of Prof. Jacob Sagiv

    Prof. Jacob Sagiv

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    Supramolecular Architecture at Interfaces (with R. Maoz)
    Supramolecular Surface Chemistry: Bottom-up Nanofabrication using Planned Self-Assembling Mono- and Multilayer Systems (with R. Maoz)
    Constructive Lithography: Contact Electrochemical Surface Patterning on Lateral Length Scales from Nanometer to Centimeter (with R. Maoz)
  • Picture of Prof. Irit Sagi

    Prof. Irit Sagi

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    Extracellular Matrix (ECM) remodeling: from biophysical principles to drug design
    ECM remodeling by unique enzymes: investigating ECM proteolysis and cross-linking that provide chemical and mechanical stimuli regulating cellular behavior in health and disease.
    Drug Design: develop specific inhibitors to control the enzymatic activity of ECM remodeling enzymes, elucidating their function, mode of action, and therapeutic potential.
    Matrix Biology: the ECM and its remodeling enzymes in physiological and pathological conditions. Development of novel tools in the fields of systems biology, immunological tools, molecular and biochemical methods, and a wide range of imaging techniques to study ECM functional remodeling.

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  • Picture of Prof. Dov Sagi

    Prof. Dov Sagi

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    Human vision, with an emphasis on processes involved in image segmentation, learning, and memory.

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  • Picture of Prof. Samuel Safran

    Prof. Samuel Safran

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    Cell Mechanics - theory
    Collaboration with:  Dennis Discher, Univ. Pennsylvania - DNA damage in migrating cells as a model of metastasis : experiments Talila Volk, Weizmann Institute - muscle cells and nuclear deformation: experiments Gary Karpen, Berekely - phase separation in the cellular nucleus: experiments Frank Juilicher - MPI Dresden - phase separation theory Tony Hyman - MPI Dresden - phase separation - biological experiments
    Soft Matter Physics Theory
    Electrostatics in soft matter - theory Cell shape and volume - theory

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  • Picture of Prof. Boris Rybtchinski

    Prof. Boris Rybtchinski

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    Organic self-assembly: nanoreactors and nanocapsules
    Solar fuels: photoinduced water splitting for hydrogen production
    Artificial photosynthesis: light-harvesting materials for solar energy conversion

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  • Picture of Prof. Yinon Rudich

    Prof. Yinon Rudich

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    Health effects of atmospheric particulate matter
    Collaboration with:  Prof. Ralf Zimmermann - Helmholtz Center Munich and University of Rostock, Germany Prof. Astrid Kiendler-Scharr - Hemholtz Ceter Juelich, Germany
    Ice nucleation by atmospheric particles
    Collaboration with:  Prof. Ido Braslvski - Hebrew University
    The transport of microorganisms in the atmosphere and their possible biogeochemical effects. Atmospheric microbiome.
    Optical properties of atmospheric organic aerosols
    Collaboration with:  Dr. Steve Brown - NOAA, Boulder CO Prof. Alexander Laskin - Purdue University

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  • Picture of Prof. Menachem Rubinstein

    Prof. Menachem Rubinstein

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    In vivo gene therapy and targeted viral oncolysis
    Collaboration with:  Gideon Schreiber Zvi Lapidot
    cancer research Hematopoietic stem cells

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  • Picture of Prof. Varda Rotter

    Prof. Varda Rotter

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    Molecular mechanisms controlling the expression of p53 in normal cells and its deregulation in cancer cells
    Involvement of p53 in cell differentiation and apoptosis: <I>in vivo</I> and in vitro models.
    Cellular proteins that specifically complex with the p53 protein.
    Cellular proteins that are induced upstream or downstream to the p53 protein following genotoxic stress.

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  • Picture of Dr. Rina Rosenzweig

    Dr. Rina Rosenzweig

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    Chaperone interactions with substrates
    Protein disaggregation machinery
    NMR of large proteins

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