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Prof. Dan Tawfik
Evolution and mechanism of enzymesMolecular evolution in man-made cell-like compartments.Directed evolution of tailor-made hydrolases (esterases, phosphoesterases, organophosphate hydrolases, and amidases) and DNA-modifying enzymes.Structure, mechanism and evolution of serum paraoxonases (PONs)The role of promiscuity and conformational plasticity in protein evolution.Directed evolution of DNA-methyltransferases and DNase inhibitorsThe stability effects of mutationsProtein evolvabilityChaperones and protein evolution
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Dr. Noam Tal Hod
Physics analysis with the ATLAS experiment at the LHC (CERN)Collaboration with: NIKHEF, The University of MichiganDirect tests of lepton universalitySearch for exotic heavy resonances, contact interactions and clockwork-like signals with dilepton final statesUpgrade of the ATLAS muon spectrometerCollaboration with: Multiple institutions (mostly from Canada, Chile, Russia, China and the USA)Construction and integration of the sTGC detectors in the New Small Wheel of ATLASLUXE experiment at DESYCollaboration with: DESY, Tel Aviv UniversityTests of QED in a strong electromagnetic field, in collisions of electron beam and high intensity laser pulseDevelopment of solid-state detectors for tracking and calorimetry
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Prof. Joel Sussman
3D Structure Funciton Studies or proteins related to AutismCollaboration with: Israel Silman3D Structure Fucntions studies of ParaoxonaseCollaboration with: Dan Tawfik & Israel SilmanApplication of ultra rapid X-ray diffraction methods to study the enzymatic mechanism of AChE in real time.Collaboration with: Israel SilmanStructure based drug design studies on AChE and beta-secretase, including studies of complexes with transition state analogs; potential drugs for the treatment of Alzheimer's disease; and snake neurotoxins.Collaboration with: Israel SilmanX-ray structural analysis and molecular biology studies on proteins from the nervous system, including acetylcholinesterase (AChE), human, torpedo, drosophila, and krait; butyrylcholinesterase; neural cell adhesion proteins with sequence similarity to AChCollaboration with: Israel Silman3D Structure Funciton of proteins related to Gaucher DiseaseCollaboration with: Tony Futerman & Israel SilmanVisualization of 3D Protein Structures via new web based tool ProteopediaCollaboration with: Jaime Prilusky & Israel Silman
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Dr. Ravid Straussman
Tumor microenvironment-mediated chemoresistanceTumor microbiomeEx-vivo Cultures of Tumor Tissues for Rapid Tailoring of Anti-Cancer TherapyPhenotypic and Mechanistic Characterization of Drug Tolerant Persister Cancer CellsSignalome: A Novel Approach for the Analysis of Signaling Pathway Activity in Cancer
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Prof. Adi Stern
Quantum interference phenomena in the fractional Quantum Hall effect. Electronic transport in strong magnetic fields.Non-abelian electronic states - quantum Hall states, topological superconductors and Majorana fermions.Fractionalized topological phases - how to construct them, how to measure them, and how to use them for topological quantum computationLow density two dimensional electronic systems.One dimensional electronic systems - electronic transport in the presence of interactions.
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Prof. Victor Steinberg
Physical hydrodynamics, hydrodynamics of complex fluids, dynamics of single flexible micro-objects (molecules, membranes, etc) in complex fluid flowsCollaboration with: Prof. G. Falkovich, Prof. V. Lebedev, Prof. Y. DubiefHydrodynamics of polymer solutions, Elastic turbulence and Turbulent mixing by polymers.Hydrodynamics and rheology of complex fluids (vesicle, capsule, worm-like micelle, etc suspensions)Dynamics and conformation of single polymer molecule, vesicle, micro-capsule, etc in complex fluid flows.Microfluidics: mixing, cell separation, random flows.Development of non-invasive local sensors for measurements of stress field in fluid flow
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