• Prof. Michael Sela

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    Importance of negligible amounts of a partner in antibody combinations
    An aptamer strategy to target oncogenic signaling in ErbB2 carrying human tumors.
    Collaboration with:  G. Mahlknecht , Y. Yarden G. Mahlknecht
    Synergy of antibodies towards decreasing pancreatic cancer.
    Collaboration with:  R. Maron, B. Schechter, Y. Yarden
    Towards vaccination: Generation of peptide mimotopes specific for anti ErbB-2 monoclonal antibodies.
    Collaboration with:  E. Witsch, Y. Yarden
    Mechanism of action of Copolymer 1 (Copaxone), a therapeutic vaccine against multiple sclerosis.
    Collaboration with:  R. Arnon
    Effective synergism by anti ErbB-2 mAb combinations comprising one mAb against the dimerization site of ErbB-2.
    Collaboration with:  Y. Yarden
    Monoclonal antibodies (mAbs) to ErbB-1 and ErbB-2 receptors and their role in potential anti-tumor strategy.
    Collaboration with:  B. Schechter, Y. Yarden
    Synergistic effects of combinations of mAb against distinct epitopes on EGFR/ErbB-1 and ErbB-2 receptors: accelerated receptor aggregation, down regulation and inhibition of tumor growth.
    Collaboration with:  B. Schechter, Y. Yarden
  • Picture of Prof. Rony Seger

    Prof. Rony Seger

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    The nuclear translocation of signaling protein as a drug target for cancer and inflammation
    The nuclear translocation of ERK
    The nuclear translocation of JNK and p38
    Develop peptide inhibitors of the nuclear translocation of ERK/JNK/p38 for the cure of cancer and inflammation
    Development of small molecular weight inhibitors of the nuclear translocation of ERK for the cure of cancer
    The subcellular localisation of AKT
    The mechanisms and roles of MEK nuclear translocation
    ERK1c in the regulation of Golgi fragmentation
    The mechanisms of golgi translocation of ERK1c
    Substrates of ERK1c in the Golgi
    Mechanism of ERK1c-regulated Golgi architecture

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  • Picture of Prof. Menahem Segal

    Prof. Menahem Segal

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    Intracellular calcium and structural/functional plasticity in cultured neurons.
    Collaboration with:  Dr. Eduard Korkotian
    Human Embryonic Stem Cells of Fragile X patients
    Collaboration with:  Prof. Dalit Ben Yosef (TAU)
    Network activity in cultured neurons
    Collaboration with:  Professor Elisha Moses (Physics)

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  • Picture of Prof. Adam Schwimmer

    Prof. Adam Schwimmer

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    String theory.
    Conformal field theory.
    Dynamics of gauge theory.
  • Picture of Prof. Michal Schwartz

    Prof. Michal Schwartz

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    The cross-talk between the immune and nervous systems – autoimmunity as a mechanism of tissue repair: Molecular, cellular, physiological and behavioral aspects.
    Immunological aspects of neuronal loss in neurodegenerative and mental disorders (Alzheimer’s, ALS, Huntingdon, Glaucoma).
    Spinal cord injury and repair
    Development of vaccination for neurodegenerative disorders.
    Neurogenesis (stem cells) and inflammation in the CNS.

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  • Picture of Prof. Oren Schuldiner

    Prof. Oren Schuldiner

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    A genetic dissection of developmental axon regeneration
    Molecular mechanisms of neuronal remodeling during development: Developmental axon pruning in Drosophila
    The role of cell-cell interaction in regulating developmental axon pruning
    The role of intracellular signaling in regulating developmental axon pruning
    The role of trafficking in regulating developmental axon pruning
    Glia and their effect on neuronal growth and remodeling

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  • Picture of Prof. Maya Schuldiner

    Prof. Maya Schuldiner

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    Uncovering tethers, functions and regulators of membrane contact sites in yeast
    Mitochondria-ER contact sites
    Peroxisome-Lipid Droplet contact sites
    Nucleus-Mitochondria contact sites
    The proteome of contact sites
    Golgi contact sites
    Targeting and translocation to Organelles
    Uncovering a role for the Ssh1, the alternative, translocon in yeast
    Deciphering targeting of proteins to mitochondria
    Targeting of membrane proteins to peroxisomes
    Targeting of low-hydrophobicity SS proteins to the ER
    Uncovering new peroxisomal proteins and their functions
    Collaboration with:  Dr. Einat Zalckvar
    Metabolite transport across the peroxisome membrane
    Peroxisome contact sites
    Peroxisome quality control
    Peroxisome targeting
    New peroxisomal enzymes and their functions
    Novel methodologies for systematic exploration of yeast organelle protein functions
    Creation of versatile yeast libraries
    High throughput electron microscopy techniques
    Translocation sensors

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  • Picture of Prof. Elad Schneidman

    Prof. Elad Schneidman

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    Biological networks
    Decision making and learning
    Animal swarming and collective behavior
    Computational Neuroscience
    Neural Coding
    Information and noise in neural populations
    Decoding neural activity
    Network organization and design
    Natural Scenes

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  • Picture of Dr. Rita Schmidt

    Dr. Rita Schmidt

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    Developing new tools for human MRI, especially at ultra-high field 7T MRI scanner, aiming to better understand the human brain function
    Developing new methods to improve the spatial and temporal resolution in functional brain MRI
    Developing new contrast methods for functional MRI to study brain function
    Advancing dedicated MR pulse sequences to achieve fast and ultrafast high quality MR imaging and spectroscopic imaging
    Boosting the accessible MR signal in localized functional brain trials

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  • Picture of Dr. Ruth Scherz-Shouval

    Dr. Ruth Scherz-Shouval

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    Tumor microenvironment
    Transcriptional profiling of stromal cells within tumors, Characterization of stromal stress responses

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