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Prof. Alex Tsafriri
Molecular regulation of ovulatory changes in mammals.Collaboration with: Helena Ashkenazi, Shmulik Motola, Xiumei Cao, Malka Popliker, Seymour Pomerantz, Marco Conti, StanfordThe roles of gonadotropins and EGF-like factors in triggering ovulation.The resumption of meiosis and its regulation.Ovulation as a tissue remodeling process.The development and demise of ovarian follicles <I>in vivo</I> and <I>in vitro</I>: the role of apoptosis.Collaboration with: Atan Gross, KerenYacobi
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Prof. Edriss S. Titi
Fluid Dynamics and geophysical flowsNavier-Stokes, Euler and related geophysical modelsTurbulence theoryPolymeric flows and non-Newtonian complex fluidNonlinear Partial Differential Equations and Dynamical SystemsInfinite-dimensional dynamical systems , Reduced dynamical systems, Numerical analysis of dissipative PDEsLimit behavior of fast and slow dynamics
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Dr. Itay Tirosh
Intra-tumor heterogeneity: combining computational and experimental approaches to understand the diversity of cells within tumors, their functions, interactions and clinical significance.Collaboration with: Mario Suva, Massachusetts General Hospital. Sid Puram, Washington University.Single cell analysis of clinical tumor samples, with a focus on gliomaComputational modeling of the tumor ecosystemTesting the function of tumor subpopulations in cell and animal models
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Prof. Reshef Tenne
Inorganic nanotubes from ternary "misfit" layered compoundsCollaboration with: Dr. R. Arenal, Laboratorio de Microscopías Avanzadas, Instituto de Nanociencia de Aragón, Universidad de Zaragoza, 50018 Zara-goza, Spain Dr. Luc Lajaunie, Departamento de Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica, Facultad de Ciencias, Uni-versidad de Cádiz, Campus Río San Pedro S/N, Puerto Real 11510, Cádiz, Spain Prof. Ernesto Joselevich, Department of Materials and Interfaces, Weizmann Institute, Rehovot 76100, Israel Dr. Lothar Houben, Chemical Research Support Department, Weizmann Institute, Rehovot 76100, Israel Prof. Janina Maultzsch, Department of Physics, FAU Erlangen-Nürnberg, 91058 Erlangen, Germany Dr. Iddo Pinkas, Chemical Research Support Department, Weizmann Institute, Rehovot 76100, IsraelSynthesis of nanotubes from misfit layered compounds (MLC), their structural electrical and optical characterization
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Prof. Dan Tawfik
Evolution and mechanism of enzymesMolecular evolution in man-made cell-like compartments.Directed evolution of tailor-made hydrolases (esterases, phosphoesterases, organophosphate hydrolases, and amidases) and DNA-modifying enzymes.Structure, mechanism and evolution of serum paraoxonases (PONs)The role of promiscuity and conformational plasticity in protein evolution.Directed evolution of DNA-methyltransferases and DNase inhibitorsThe stability effects of mutationsProtein evolvabilityChaperones and protein evolution
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Dr. Noam Tal Hod
Physics analysis with the ATLAS experiment at the LHC (CERN)Collaboration with: NIKHEF, The University of MichiganDirect tests of lepton universalitySearch for exotic heavy resonances, contact interactions and clockwork-like signals with dilepton final statesUpgrade of the ATLAS muon spectrometerCollaboration with: Multiple institutions (mostly from Canada, Chile, Russia, China and the USA)Construction and integration of the sTGC detectors in the New Small Wheel of ATLASLUXE experiment at DESYCollaboration with: DESY, Tel Aviv UniversityTests of QED in a strong electromagnetic field, in collisions of electron beam and high intensity laser pulseDevelopment of solid-state detectors for tracking and calorimetry
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Prof. Joel Sussman
3D Structure Funciton Studies or proteins related to AutismCollaboration with: Israel Silman3D Structure Fucntions studies of ParaoxonaseCollaboration with: Dan Tawfik & Israel SilmanApplication of ultra rapid X-ray diffraction methods to study the enzymatic mechanism of AChE in real time.Collaboration with: Israel SilmanStructure based drug design studies on AChE and beta-secretase, including studies of complexes with transition state analogs; potential drugs for the treatment of Alzheimer's disease; and snake neurotoxins.Collaboration with: Israel SilmanX-ray structural analysis and molecular biology studies on proteins from the nervous system, including acetylcholinesterase (AChE), human, torpedo, drosophila, and krait; butyrylcholinesterase; neural cell adhesion proteins with sequence similarity to AChCollaboration with: Israel Silman3D Structure Funciton of proteins related to Gaucher DiseaseCollaboration with: Tony Futerman & Israel SilmanVisualization of 3D Protein Structures via new web based tool ProteopediaCollaboration with: Jaime Prilusky & Israel Silman
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Dr. Ravid Straussman
Tumor microenvironment-mediated chemoresistanceTumor microbiomeEx-vivo Cultures of Tumor Tissues for Rapid Tailoring of Anti-Cancer TherapyPhenotypic and Mechanistic Characterization of Drug Tolerant Persister Cancer CellsSignalome: A Novel Approach for the Analysis of Signaling Pathway Activity in Cancer
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