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Prof. Maya Schuldiner
Uncovering tethers, functions and regulators of membrane contact sites in yeastMitochondria-Peroxisome contact sitesPeroxisome-Plasma membrane contact sitesLipid Droplet-Mitochondria contact sitesThe proteome of contact sitesTargeting and translocation to OrganellesUncovering a role for the Ssh1, the alternative, translocon in yeastDeciphering targeting of proteins to mitochondriaTargeting of membrane proteins to peroxisomesTargeting priority of matrix proteins to peroxisomesUncovering new peroxisomal proteins and their functionsCollaboration with: Dr. Einat ZalckvarMetabolite transport across the peroxisome membranePeroxisome contact sitesPeroxisome quality controlPeroxisome targetingNew peroxisomal enzymes and their functionsNovel methodologies for systematic exploration of yeast organelle protein functionsCreation of versatile yeast librariesHigh throughput electron microscopy techniquesTranslocation sensorsHigh throughput expansion microscopy in yeast
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Prof. Avigdor Scherz
Quantification of atoms, groups and molecules electronegati using metal substituted bacteriochlorophylls and application to chemical reactivity.Resolving the forces which drive membrane protein assembly.The mechenism behind generation of reactive oxygen species (ROS) by illuminating novel bacteriochlorophyll derivatives and their application in photodynamic therapy (PDT) of tumors.
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Prof. Yardena Samuels
Synthetic lethal interaction network of melanomaIdentification of melanoma hub interactomesCRISPR screens to reveal driver gene interactions and drug resistance genesDecipher the immuno-genetic interactions between melanoma and T cellsHLA peptidome analysis of metastatic melanoma lesions
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Prof. Jacob Sagiv
Supramolecular Architecture at Interfaces (with R. Maoz)Supramolecular Surface Chemistry: Bottom-up Nanofabrication using Planned Self-Assembling Mono- and Multilayer Systems (with R. Maoz)Constructive Lithography: Contact Electrochemical Surface Patterning on Lateral Length Scales from Nanometer to Centimeter (with R. Maoz)
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Prof. Samuel Safran
Cell Mechanics - theoryCollaboration with: Dennis Discher, Univ. Pennsylvania - DNA damage in migrating cells as a model of metastasis : experiments Talila Volk, Weizmann Institute - muscle cells and nuclear deformation: experiments Gary Karpen, Berekely - phase separation in the cellular nucleus: experimentsSoft Matter Physics TheoryElectrostatics in soft matter - theory Cell shape and volume - theory
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