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Prof. Eitan Bibi
Structure/function studies of the <I>E. coli</I> multidrug transporter, MdfA.Collaboration with: Klaas Martinus Pos, Goethe University, Frankfurt, Germany Hassane Mchaourab, Vanderbilt University, Nashville, TN, USA Melissa Brown, Flinders University, Adelaide SA, AustraliaThe multidrug recognition pocket of MdfA (genetic and biochemical studies)3D crystallization of MdfAMechanism of MdfA-mediated multidrug transport (proton/drug antiport)Conformational behavior of MdfAMembrane protein biogenesis in E. coliCollaboration with: Gert Bange, Philipps University Marburg, GermanyFtsY, the essential prokaryotic SRP-receptor: biogenesis and functionMembrane targeting and association of ribosomes in E. coli.Membrane targeting and association of mRNAs encoding membrane proteins
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Prof. Alexander D. Bershadsky
Integrin-mediated cell-matrix adhesions as mechanosensors: molecular requirements for the force-induced focal adhesion growth.Cell-cell contact-dependent regulation of the actin cytoskeleton and microtubule system: Role of p120 catenin and other components of cadherin adhesion complex.Role of myosin-driven contractility in the retrograde surface flow and cell motility.Cooperation between neuregulin, ErbB-family receptors, and cell surface heparan sulfate proteoglycans in the regulation of cell motility and morphogenesis.
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Prof. Brian Berkowitz
Development of chemical methods for remediation of water polluted by organic compounds and heavy metals.Fluid flow and chemical transport in groundwater systems.Percolation, scaling and statistical physics models of structural and dynamic processes in geological formations.Experimental and theoretical analysis of reactive transport and precipitation/dissolution patterns in porous media.
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