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Prof. Yardena Samuels
Synthetic lethal interaction network of melanomaIdentification of melanoma hub interactomesCRISPR screens to reveal driver gene interactions and drug resistance genesDecipher the immuno-genetic interactions between melanoma and T cellsHLA peptidome analysis of metastatic melanoma lesions
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Prof. Yoram Salomon
Anti-cancer treatments :Development of novel bacteriochlorophyll-based drugs for photochemotherapy.Boron neutron capture therapy.Reactive oxygen species, their generation by bacteriochlorophyll and light, their role in signal transduction and mechanisms of cell and tumor destruction.Vascular biology and vascular destruction.
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Prof. Jacob Sagiv
Supramolecular Architecture at Interfaces (with R. Maoz)Supramolecular Surface Chemistry: Bottom-up Nanofabrication using Planned Self-Assembling Mono- and Multilayer Systems (with R. Maoz)Constructive Lithography: Contact Electrochemical Surface Patterning on Lateral Length Scales from Nanometer to Centimeter (with R. Maoz)
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Prof. Menachem Rubinstein
Role of oxidative stress in type 2 diabetesCollaboration with: Mike WalkerMetabolic diseasesCAR-T optimizationCollaboration with: Zelig EshharGene therapy in cancerRole of C/EBPbeta in multidrug resistanceCollaboration with: Chiara Riganti (Univ. Torino, Italy)Cancer ResearchAttenuation of chemotherapy side effectsCollaboration with: Gillian Dank (Koret School of Veterinary Medicine of the Hebrew University of Jerusalem)Cancer Research
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Prof. Israel Rubinstein
Functional NanomaterialsSelf-assembled supramolecular nanostructures on surfaces (with A. Vaskevich, H. Leader)Nanoparticle organization on surfaces using coordination layer-by-layer assembly (with A. Vaskevich, H. Leader)Plasmonic systems based on metal nano-island films prepared by evaporation/annealing (with A. Vaskevich)Application of metal nanoisland films in chemical and biological sensing using localized surface plasmon resonance spectroscopy (with A. Vaskevich)
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Prof. Varda Rotter
Molecular mechanisms controlling the expression of p53 in normal cells and its deregulation in cancer cellsInvolvement of p53 in cell differentiation and apoptosis: <I>in vivo</I> and in vitro models.Cellular proteins that specifically complex with the p53 protein.Cellular proteins that are induced upstream or downstream to the p53 protein following genotoxic stress.
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