Electrical activity in small hippocampal networks

Intracellular calcium and structural/functional plasticity in cultured neurons.

Activity maintains survival of neurons in culture

Hippocampal structure and function during stress

Pathological mechanism in the CNS of various multiple sclerosis animal models.

Neuroprotection, neurogenesis and remyelination – consequences of Glatiramer Acetate treatment in EAE.

Mechanism of action of Copolymer 1 (Copaxone®), a therapeutic vaccine against multiple sclerosis.

Development of universal vaccine for the control of allergic responses.

Study of colorectal induced tumors in colitis.

Redirecting regulatory T cells for adoptive cell therapy of autoimmune inflammation.

Redirecting effector T cells for adoptive cell treatment of cancer.

Electron transfer mechanisms in proteins.

Antigen recognition and trans-membrane signaling by immuno-receptors.

An aptamer strategy to target oncogenic signaling in ErbB2 carrying human tumors.

Synergy of antibodies towards decreasing pancreatic cancer.

Towards vaccination: Generation of peptide mimotopes specific for anti ErbB-2 monoclonal antibodies.

Mechanism of action of Copolymer 1 (Copaxone), a therapeutic vaccine against multiple sclerosis.

Effective synergism by anti ErbB-2 mAb combinations comprising one mAb against the dimerization site of ErbB-2.

Monoclonal antibodies (mAbs) to ErbB-1 and ErbB-2 receptors and their role in potential anti-tumor strategy.

Synergistic effects of combinations of mAb against distinct epitopes on EGFR/ErbB-1 and ErbB-2 receptors: accelerated receptor aggregation, down regulation and inhibition of tumor growth.

Role of FABP4 and PPARgamma in ER stress - imlications in the metabolic syndrome

Cytokine receptors and binding proteins

The mode of action of the soluble LDL receptor as an antiviral protein

Regulation and role of endoplasmic reticulum stress in cell survival and cell death

Chemotaxis of bacteria

Sperm guidance in humans

Studying large protein complexes involved in the protein degradation pathway using a novel mass spectrometry approach.

* Neurophysiological recordings of individual neurons in freely flying bats, using radio-telemetry -- in hippocampus and entorhinal cortex

* The neural basis of behavior

* From the bat's biological sonar system to spatial cognition

* Mammalian hippocampus (hippocampal place cells) and entorhinal cortex (grid cells)

* Neuronal circuits: hippocampal and entorhinal neural activity in freely-behaving echolocating bats

* Neural codes for 2-D and 3-D space in the mammalian brain

* Neurobiology of learning and memory: a systems neuroscience approach

Earth and environmental sciences education: research, development and implemntation from K-12.

The outdoor as a learning environment