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September 12, 2014

  • Date:03WednesdayMarch 2021

    A quantitative perspective on the geo / bio / socio spheres interface

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    Time
    09:00 - 10:00
    Title
    MSc Thesis Defense via Zoom
    Location
    https://weizmann.zoom.us/j/94410804953?pwd=M1BmbmJ3Y29haDZ4a2xrSkhhVHE5dz09Password997244
    LecturerLior Greenspoon
    Prof. Ron Milo's Lab., Department of Plant and Environmental Sciences
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:04ThursdayMarch 2021

    Inflammation, Metabolism and Immunity in Liver Cancer: From Pathogenesis to Treatment

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    Time
    09:00 - 10:00
    LecturerDr. Michael Karin
    Departments of Pharmacology and Pathology, University of California San Diego, School of Medicine
    Organizer
    Dwek Institute for Cancer Therapy Research
    Contact
    Lecture
  • Date:04ThursdayMarch 2021

    Using Ultra-High Field MRI to Study the Human Brain

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    Time
    09:00 - 10:00
    Location
    ZOOM
    LecturerDr. Edna Furman-Haran
    MRI Unit
    Organizer
    Department of Life Sciences Core Facilities
    Homepage
    Contact
    Lecture
  • Date:04ThursdayMarch 2021

    “Beyond mapping: perturbation as the key to understanding function”

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    Time
    09:30 - 10:30
    LecturerDr. Michal Ramot
    Dept Neurobiology, WIS
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    AbstractShow full text abstract about Zoom link: https://weizmann.zoom.us/j/94322871667?pwd=NXkvO...»
    Zoom link:
    https://weizmann.zoom.us/j/94322871667?pwd=NXkvODRXWVZlbW9hSEtScHN1M0F4dz09
    passcode: 870711


    Neuroimaging has allowed us to map the correlations between brain activation, and external stimuli or behaviour. Yet these correlations can only hint at the function of the brain regions involved. In order to more casually investigate these relationships between brain and behaviour, we must perturb the brain, and see what changes this brings about in behaviour. I will provide a framework for doing so through covert neurofeedback. This technique allows us to perturb brain networks by reinforcing desired network states directly, through a reward orthogonal to the networks being trained. Yet a prerequisite for such a test of function and causality, is a strong hypothesis regarding the purported link between a specific network and behaviour. We must therefore also develop better behavioural tools, in order to establish such links.
    Lecture
  • Date:04ThursdayMarch 2021

    Radiocarbon and geochemical investigation of corals from the northern Indian Ocean

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    Time
    11:30 - 11:30
    Location
    https://weizmann.zoom.us/j/6168548886 Passcode: 976012
    LecturerDr. Harsh Raj
    Geosciences Division, Physical Research Laboratory, Navrangpura, Ahmedabad, India
    Contact
    Lecture
  • Date:07SundayMarch 202109TuesdayMarch 2021

    Biomolecular Phase Separartion: A Student Organzied Conference

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    Time
    08:00 - 08:00
    Location
    The David Lopatie Conference Centre
    Chairperson
    Yair Harel
    Conference
  • Date:07SundayMarch 2021

    Department of Molecular Genetics department seminar

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    Time
    13:00 - 13:30
    Title
    “Ambiguity resolution in the TGFb/ BMP pathways through combinatorial SMAD complex formation”
    Location
    https://weizmann.zoom.us/j/92440011671?pwd=Yk9kQUpqWkJnUmFMRUlnT0NaSlliUT09
    LecturerJohannes Auth
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:08MondayMarch 2021

    Proteins mobility, affinity & stability for optimized function

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    Time
    11:00 - 12:00
    Location
    https://weizmann.zoom.us/j/98063488104?pwd=N3VqTC9sU1A4RHVDZ1dhOGVxbU1iUT09
    LecturerProf. Koby Levy
    Department of Structural Biology
    Organizer
    Faculty of Chemistry
    Contact
    AbstractShow full text abstract about Proteins, which are at the heart of many biological processe...»
    Proteins, which are at the heart of many biological processes, are involved in a variety of self-assembly processes that are controlled by various chemical and physical interactions. Quantifying the driving forces that govern these processes and particularly the trade-offs between them is essential to obtaining a more complete understanding of protein dynamics and function. In my lecture, I will discuss the molecular determinants that govern linear diffusion of proteins along DNA or along microtubules. These and other cellular processes, such as protein folding, are subject to conflicting forces some of which are regulated by post-translational modifications. Understanding the trade-offs between the stability, affinity and mobility is not only essential to decipher transport processes in the cell but also for formulating concepts for their engineering. I will discuss the power of computational models in formulating fundamental biomolecular concepts and in predicting novel principles of cellular function or for its optimization.
    Colloquia
  • Date:08MondayMarch 2021

    Women's Day 2021

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    Time
    12:30 - 15:00
    Title
    Save the date
    Contact
    Lecture
  • Date:09TuesdayMarch 2021

    To be announced

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    Time
    10:00 - 10:30
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerDr. Mattia Morandi
    Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    Lecture
  • Date:09TuesdayMarch 2021

    Diatom modulation of associated bacteria

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    Time
    11:30 - 12:30
    Title
    Guest Seminar via Zoom
    Location
    https://weizmann.zoom.us/j/91943922657?pwd=QnF1eThwV0lWTk45ZWFBWnlHeGx2Zz09Password620591
    LecturerDr. Ahmed Shibl
    Marine Microbial Ecology Lab - New York University Abu Dhabi
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:09TuesdayMarch 2021

    Dissecting the Alzheimer’s brain: from disease single cells to cellular communities

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    Time
    12:30 - 13:30
    LecturerProf. Naomi Habib
    Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about Alzheimer’s disease (AD) is one of the most pressing globa...»

    Alzheimer’s disease (AD) is one of the most pressing global medical issues to date with no effective therapeutic strategies. Despite extensive research much remains unknown regarding the crosstalk between brain cells and the role of non-neuronal cells in the progression of Alzheimer’s disease (AD). We use single nucleus RNA-sequencing and machine learning algorithms to build detailed cellular maps of mice and human brain and to follow molecular changes in each cell type along disease progression. Our maps revealed new disease associated states in glia cells as well as unique multi-cellular communities linked to AD. Specifically, we found a link between populations of disease-associated astrocytes (DAAs), microglia, oligodendrocytes and GABAergic neurons to AD related traits in mouse models and in post-mortem human brains. Expanding the data analysis across multiple cell types, we found co-occurrences of cellular populations across individuals, which we define as multi-cellular communities. Among these communities we discovered a unique cellular community linked to cognitive decline and Alzheimer’s disease pathology. These new insights are shaping our understanding of the unique cellular environment of the Alzheimer’s disease brains.


    Zoom link to join:
    https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09

    Meeting ID: 966 0803 3618
    Password: 564068

    Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
    Lecture
  • Date:14SundayMarch 2021

    Nucleation fronts initiate frictional motion

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    Time
    11:00 - 12:00
    LecturerProf. Jay Fineberg
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    AbstractShow full text abstract about Zoom LInk: https://weizmann.zoom.us/j/97917323609?pwd=OGpCV...»
    Zoom LInk: https://weizmann.zoom.us/j/97917323609?pwd=OGpCVzNKWGlCSS9lbTIyS0FtN1lHUT09

    Recent experiments have demonstrated that rapid rupture fronts, akin to earthquakes, mediate the transition to frictional motion. Moreover, once these dynamic rupture fronts ("laboratory earthquakes" ) are created, their singular form, dynamics and arrest are well-described by fracture mechanics. Ruptures, however, need to be created within initially rough frictional interfaces, before they are able to propagate. This is the reason that ``static friction coefficients” are not well-defined; frictional ruptures can nucleate for a wide range of applied forces. A critical open question is, therefore, how the nucleation of rupture fronts actually takes place. We experimentally demonstrate that rupture front nucleation is prefaced by slow nucleation fronts. These nucleation fronts, which are self-similar, are not described by fracture mechanics. They emerge from initially rough frictional interfaces at a well-defined stress threshold, evolve at characteristic velocity and time scales governed by stress levels, and propagate within a frictional interface to form the initial rupture from which fracture mechanics take over. These results are of fundamental importance to questions ranging from earthquake nucleation and prediction to processes governing material failure.
    Lecture
  • Date:14SundayMarch 2021

    Department of Molecular Genetics departmental seminar

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    Time
    13:00 - 13:30
    Title
    “Quantitative analysis by 3D MAPs reveals new cell morphogenetic behaviors which drive bone growth”
    Location
    https://weizmann.zoom.us/j/97246877306?pwd=R1FSemROR3hseTNWRDhQeVNBSExWZz09
    LecturerSarah Rubin
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:16TuesdayMarch 2021

    Supported Nanocomposites for Water Decontamination

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    Time
    10:00 - 11:00
    Location
    https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09
    LecturerInes Zucker
    Tel Aviv University
    Organizer
    Department of Earth and Planetary Sciences
    Contact
    AbstractShow full text abstract about Contamination of drinking water sources by a variety of orga...»
    Contamination of drinking water sources by a variety of organic and inorganic compounds demands more efficacious and reliable treatment technologies. However, conventional water treatment technologies remain chemically demanding, energy intensive, and ineffective in removing key trace contaminants. As such, nanotechnology-based approaches have been increasingly explored to enhance or replace traditional remediation methods because of the high reactivity and tunable-properties of nanomaterials. In her talk, Dr. Zucker will provide an overview on the current status of nano-enabled water decontamination, including promising opportunities and barriers for implementation. Specifically, the application of molybdenum disulfide (MoS2) for heavy metal removal will be extensively discussed as a case study, where material properties, removal mechanisms, and large-scale applications are optimized.
    Lecture
  • Date:16TuesdayMarch 2021

    Root plasma membrane aquaporins regulate root hydraulics, shoot gas exchange and plant growth

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    Time
    11:30 - 12:30
    Title
    Guest Seminar via Zoom
    Location
    https://weizmann.zoom.us/j/92082019125?pwd=eUdmSGZIVEc4d3lMWTNNZU02SUZpdz09 Password 879831
    LecturerDr. Nir Sade
    School of Plant Sciences and Food Security, The Institute for Cereal Crops Improvement, Tel-Aviv University
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:16TuesdayMarch 2021

    Cortical Layer 1 – The Memory Layer?

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    Time
    12:30 - 12:30
    LecturerDr. Guy Doron
    Humboldt University of Berlin Neurocure Cluster of Excellence, Berlin
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about The hippocampus and related medial temporal lobe structures ...»
    The hippocampus and related medial temporal lobe structures (entorhinal cortex, perirhinal cortex, etc.) play a vital role in transforming experience into long-term memories that are then stored in the cortex, however the cellular mechanisms which designate single neurons to be part of a memory trace remain unknown. Part of the difficulty in addressing the mechanisms of transformation of short-term to long-term memories is the distributed nature of the resulting “engram” at synapses throughout the cortex. We therefore used a behavioral paradigm dependent on both the hippocampus and neocortex that enabled us to generate memory traces rapidly and reliably in a specific cortical location, by training rodents to associate the direct electrical microstimulation of the primary sensory neocortex with a reward. We found that medial-temporal input to neocortical Layer 1 (L1) gated the emergence of specific firing responses in subpopulations of Layer 5 pyramidal neurons marked by increased burstiness related to apical dendritic activity. Following learning and during memory retrieval, these neocortical responses became independent of the medial-temporal influence but continued to evoke behaviour with single bursts sufficient to elicit a correct response. These findings suggest that L1 is the locus for hippocampal-dependent associative learning in the neocortex, where memory engrams are established in subsets of pyramidal neurons by enhancing the sensitivity of tuft dendrites to contextual inputs and driving burst firing.

    Zoom link to join- https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09

    Meeting ID: 966 0803 3618
    Password: 564068
    Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
    Lecture
  • Date:16TuesdayMarch 2021

    Ecosystem ecology to inform global biodiversity restoration

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    Time
    13:00 - 14:00
    Title
    SAERI - Sustainability and Energy Research Initiative seminar series
    Location
    via zoom
    LecturerProf. Thomas Crowther
    Department of Environmental Systems Science, ETH Zurich, Switzerland
    Organizer
    Weizmann School of Science
    Contact
    Lecture
  • Date:18ThursdayMarch 2021

    Solving computational problems with coupled lasers

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    Time
    11:15 - 12:30
    Location
    https://weizmann.zoom.us/j/94477142638?pwd=aWNlZGVzNmdJdnJVZVNZUi9sZ0VBZz09
    LecturerProf. Nir Davidson
    Weizmann Institute of Science
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about Computational problems may be solved by realizing physics sy...»
    Computational problems may be solved by realizing physics systems that can simulate them. Here we present a new system of coupled lasers in a modified degenerate cavity that is used to solve difficult computational tasks. The degenerate cavity possesses a huge number of degrees of freedom (300,000 modes in our system), that can be coupled and controlled with direct access to both the x-space and k-space components of the lasing mode. Placing constraints on these components are mapped on different computational minimization problems. Due to mode competition, the lasers select the mode with minimal loss to find the solution. We demonstrate this ability for simulating XY spin systems and finding their ground state, for phase retrieval, for imaging through scattering medium, and more.
    Colloquia
  • Date:18ThursdayMarch 2021

    RNA Therapeutics: From Gene Silencing to Gene Editing

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    Time
    14:00 - 15:00
    LecturerDan Peer, PhD
    Director, Laboratory of Precision NanoMedicine Tel Aviv University
    Organizer
    Dwek Institute for Cancer Therapy Research
    Contact
    Lecture

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