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June 06, 2016
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Date:11MondayMarch 2019Conference
2nd Israeli Synthetic biology meeting: recent advancements in academia and industry
More information Time 09:00 - 18:00Location The David Lopatie Conference CentreChairperson Roee Ben-NissanHomepage -
Date:11MondayMarch 2019Colloquia
Life Science Colloquium
More information Time 11:00 - 12:00Title Life at the edge of sightLocation Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Roberto Kolter
Microbioloogy & Immunology, Harvard Medical School, BostonContact -
Date:11MondayMarch 2019Colloquia
"Supramolecular Assembly with Mechanical Action"
More information Time 11:00 - 12:30Location Max and Lillian Candiotty BuildingLecturer Prof. Myongsoo Lee
Jilin UniversityOrganizer Faculty of ChemistryContact Abstract Show full text abstract about In this symposium, I will introduce our recent results how t...» In this symposium, I will introduce our recent results how to construct dynamic self-assembled nanostructures exhibiting switchable functions, inspired by life systems. For example, synthetic tubular pores are able to undergo open-closed gating driven by an external signal, which function as an artificial enzyme. When self-assembled tubules embed DNA inside the hollow cavities, the DNA-coat assembly undergoes collective motion in helicity switching. In the case of toroid assembly, the static toroids are able to undergo spontaneous helical growth when they switch into out-of-equilibrium state. The helical growing drives actuation of spherical vesicles into tubular vesicles, reminiscent of microtubles. Moving from 1-D to 2-D structures, the internal pores are able to form chiral interior which selectively capture only one enantiomer in racemic solution with pumping action. I will discuss recently discovered these results with their complex functions. -
Date:11MondayMarch 2019Lecture
Making the right disulfides-- the role of redox and protein structure
More information Time 11:00 - 12:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Neil Bulleid
Director of the Institute of Molecular Cell & Systems Biology University of GlasgowOrganizer Department of Chemical and Structural BiologyContact -
Date:11MondayMarch 2019Lecture
The Israel Young Academy
More information Time 13:00 - 13:00Title The Israel Young Academy - Leveraging the Potential of the Israeli AcademyLocation Jacob Ziskind BuildingLecturer Prof. Eran Bouchbinder
Department of Chemical and Biological PhysicsOrganizer Department of Chemical and Biological PhysicsContact Abstract Show full text abstract about Professor Eran Bouchbinder recently completed his term as Ch...» Professor Eran Bouchbinder recently completed his term as Chair of the Israel Young Academy. To mark the event and to learn more about the Israel Young Academy, Eran will describe the role of the Young Academy in the Israeli academic society -
Date:12TuesdayMarch 2019Conference
Automorphic Forms Theory. In Memory of Ilya Piatetski-Shapiro
More information Time 08:00 - 17:00Location The David Lopatie Conference CentreChairperson Vladimir BerkovichHomepage -
Date:12TuesdayMarch 2019Lecture
Spectral editing techniques for chemical exchange saturation transfer imaging
More information Time 10:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Prof. Jiadi Xu
Kennedy Krieger Institute and Johns Hopkins School of MedicineOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Chemical exchange saturation transfer (CEST) imaging is a re...» Chemical exchange saturation transfer (CEST) imaging is a relatively new MRI technology allowing the detection of low concentration endogenous cellular proteins and metabolites indirectly through water. CEST MRI is still under development and one major impediment for more widespread application is limited specificity due to spectral overlap of CEST signal from other metabolites and proteins. In this presentation, I will demonstrate several novel CEST spectral editing techniques developed by our group to extract information from CEST images, such as one variable delay multi pulse (VDMP) CEST that acts an exchange rate filter to separate CEST effects from the confounding factors, one ultra-short echo (UTE)-CEST method that can monitor in vivo protein aggregation process and one polynomial and Lorentzian line-shape fitting (PLOF) CEST that can detect creatine and phosphocreatine in tissue with high specialty. Their applications on the stroke and Alzheimer’s disease models will be covered. At last, I will explore one artificial neural network approach to overcome the challenges of implementing the CEST technique on 3T clinical MRI scanners. -
Date:12TuesdayMarch 2019Lecture
A non coding RNA/protein dancing couple, 7SK and HEXIM
More information Time 10:00 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Olivier Bensaude
IBENS - CNRS UMR 8541 Ecole Normale Supérieure, PARISOrganizer Department of Biomolecular SciencesContact -
Date:12TuesdayMarch 2019Lecture
Towards Increased Complexity in Dynamic Covalent Systems and Metal-Organic Cages
More information Time 11:00 - 12:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Anna McConnell
Otto-Diels-Institut für Organische Chemie Christian-Albrechts-Universität zu KielOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Anna McConnell, Otto Diels Institute of Organic Chemistry, C...» Anna McConnell, Otto Diels Institute of Organic Chemistry, Christian-Albrechts-Universität zu Kiel
The supramolecular toolbox enables the self-assembly of supramolecular architectures from relatively simple building blocks through reversible, weak non-covalent interactions. Supramolecular architectures with increased complexity are appealing targets for not only the synthetic challenge but also for the potential to access new types of chemistry and functionality. Efforts towards increasing the complexity of both the supramolecular architecture and stimuli-responsive behaviour[1] in dynamic covalent and metal-organic cage systems will be presented. In one approach, the post-assembly reduction of achiral iminoboronates gives access to three isomeric products containing two stereogenic centres and two of these products interconvert through unusual lability of the covalent B-N bonds.[2] In another approach, progress towards the development and characterisation of spin-crossover cages[3] with increased complexity will be discussed.
References
[1] A. J. McConnell, C. S. Wood, P. P. Neelakandan, J. R. Nitschke, Chem. Rev. 2015, 115, 7729-7793.
[2] E. N. Keyzer, A. Sava, T. K. Ronson, J. R. Nitschke, A. J. McConnell, Chem. Eur. J. 2018, 24, 12000-12005.
[3] A. J. McConnell, Supramol. Chem. 2018, 30, 858-868.
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Date:12TuesdayMarch 2019Lecture
Dr. Neta Regev-Rudzki - Communication between malaria parasites
More information Time 12:00 - 12:00Title Communication between malaria parasitesLocation Dolfi and Lola Ebner AuditoriumLecturer Prof. Neta Regev-Rudzki Organizer Communications and Spokesperson DepartmentHomepage Contact -
Date:12TuesdayMarch 2019Lecture
What makes tetra-ubiquitin a preferred signal for targeting proteins to the proteasome?
More information Time 14:00 - 15:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Michael Glickman
TechnionOrganizer Department of Chemical and Structural BiologyContact -
Date:12TuesdayMarch 2019Lecture
The odor identity puzzle: How odor information can be shared across hemispheres if there are no cortical odor maps?
More information Time 14:00 - 14:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Dr. Rafi Haddad
The Gonda Multidisciplinary Brain Research Center Bar-Ilan UniversityOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Sensory input reaching the brain from bilateral and offset c...» Sensory input reaching the brain from bilateral and offset channels is nonetheless perceived as unified. This unity could be explained by simultaneous projections to both hemispheres, or inter-hemispheric information transfer between sensory cortical maps. Odor input, however, is not topographically organized, nor does it project bilaterally, making olfactory perceptual unity enigmatic. Here we report a circuit that interconnects mirror-symmetric isofunctional output cells between the mouse olfactory bulbs. Connected neurons respond to similar odors from ipsi- and contra-nostrils, whereas unconnected neurons do not respond to odors from the contralateral nostril. This circuit enables sharing of odor information across hemispheres in the absence of a cortical topographical organization, suggesting that olfactory glomerular maps are the equivalent of cortical sensory maps found in other senses. -
Date:13WednesdayMarch 2019Lecture
Developmental Club Series 2018-2019
More information Time 10:00 - 10:00Title “Regulation of cell cycle by nuclear mechanical inputs”Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Talila Volk Organizer Department of Molecular GeneticsContact -
Date:13WednesdayMarch 2019Lecture
The Lab on a Beam: From Learning Physics to Atomic Manipulation in Scanning Transmission Electron Microscopy
More information Time 11:00 - 12:00Location Perlman Chemical Sciences BuildingLecturer Dr. Sergei Kalinin
Institute for Functional Imaging of Materials (IFIM), Oak Ridge National LabOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Atomically-resolved imaging of materials has become the main...» Atomically-resolved imaging of materials has become the mainstay of modern materials science, as enabled by advent of aberration corrected scanning transmission electron microscopy (STEM). However, the wealth of quantitative information contained in the fine details of atomic structure or spectra remains largely unexplored. In this talk, I will present the new opportunities enabled by physics-informed big data and machine learning technologies to extract physical information from static and dynamic STEM images. The deep learning models trained on theoretically simulated images or labeled library data demonstrate extremely high efficiency in extracting atomic coordinates and trajectories, converting massive volumes of statistical and dynamic data into structural descriptors. I further present a method to take advantage of atomic-scale observations of chemical and structural fluctuations and use them to build a generative model (including near-neighbor interactions) that can be used to predict the phase diagram of the system in a finite temperature and composition space. Similar approach is applied to probe the kinetics of solid-state reactions on a single defect level and defect formation in solids via atomic-scale observations. Finally, synergy of deep learning image analytics and real-time feedback further allows harnessing beam-induced atomic and bond dynamics to enable direct atom-by-atom fabrication. Examples of direct atomic motion over mesoscopic distances, engineered doping at selected lattice site, and assembly of multiatomic structures will be demonstrated. These advances position STEM towards transition from purely imaging tool for atomic-scale laboratory of electronic, phonon, and quantum phenomena in atomically-engineered structures. -
Date:13WednesdayMarch 2019Lecture
MM Special Guest Seminar: Hiderou Yoshida, Ph. D., will lecture about "New insights into ER- and Golgi- stress responses."
More information Time 13:00 - 14:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Hiderou Yoshida, Ph. D.
Department of Biochemistry and Molecular Biology University of Hyogo, JapanOrganizer Department of Systems ImmunologyContact -
Date:14ThursdayMarch 2019Conference
EPScon 2019
More information Time 08:00 - 08:00Location The David Lopatie Conference CentreChairperson Madi AmerOrganizer Department of Earth and Planetary SciencesHomepage -
Date:14ThursdayMarch 2019Colloquia
Silicon Day: Plant Minerals in Modern and Archaeological Environments
More information Time 09:00 - 12:00Title If you intend to attend, please let us know in advanced.Location Faculty of Agriculture, Cabin – 8Lecturer Rivka Elbaum, Nerya Zexer, Evgenia Vaganov, Steve Weiner, Rosa M. Albert, Oriol Andreu, and Filipe Natalio., Prof. Elisabetta Boaretto Organizer Academic Educational ResearchContact -
Date:14ThursdayMarch 2019Lecture
Nonlinear light-matter interaction: from superconducting qubits to spins in diamond
More information Time 10:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Prof. Eyal Buks
Faculty of Electrical Engineering, TechnionOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about The talk is devoted to the study of the light-matter inter...»
The talk is devoted to the study of the light-matter interaction in the nonlinear regime using three different cavity quantum electrodynamics (CQED) systems. The matter under study is a Josephson flux qubit in the first experiment [1], a spin ensemble of diphenylpicrylhydrazyl (DPPH) molecules in the second one, and different spin ensembles in a diamond lattice in the third one [3]. In all three experiments the matter under study interact with photons (light) confined in a superconducting microwave resonator (cavity). A variety of nonlinear effects are explored, including super-harmonic resonances, multi-photon resonances, effective cavity heating and cooling and motional narrowing induced by quantum-jumps. The effect of nonlinearity on spin detection sensitivity will be discussed.
1. Eyal Buks, Chunqing Deng, Jean-Luc F.X. Orgazzi, Martin Otto and Adrian Lupascu, Phys. Rev. A 94, 033807 (2016).
2. Hui Wang, Sergei Masis, Roei Levi, Oleg Shtempluk and Eyal Buks, Phys. Rev. A 95, 053853 (2017).
3. Nir Alfasi, Sergei Masis, Roni Winik, Demitry Farfurnik, Oleg Shtempluck, Nir Bar-Gill and Eyal Buks, Phys. Rev. A 97 (2018).
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Date:14ThursdayMarch 2019Lecture
A linear multisite phosphorylation code controls cell cycle progression
More information Time 11:00 - 12:00Location Max and Lillian Candiotty BuildingLecturer Prof. Mart Loog Organizer Department of Immunology and Regenerative BiologyContact -
Date:14ThursdayMarch 2019Lecture
Genetic programs that differentiate tomato axillary shoots from their primary shoot progenitor
More information Time 11:00 - 11:00Title PhD thesis defenseLocation Nella and Leon Benoziyo Building for Biological SciencesLecturer Anna Goren
Prof. Yuval Eshed's lab, Department of Plant and Environmental SciencesOrganizer Department of Plant and Environmental SciencesContact
