Publishing research papers is a cornerstone of working in life sciences, but do you know what actually happens to your manuscript once it is submitted to a scientific journal? Anne Nielsen – scientific editor for The EMBO journal – will take you behind the scenes of scientific publishing at EMBO and explain how editors make decisions, find referees and work with authors to improve the revised manuscript. She will also discuss some of the challenges faced by the current publishing landscape, talk about the efforts EMBO is making to prevent errors and fraud from entering the literature, and offer advice on manuscript writing and submission.