Monocyte and Brain Macrophage Functions in Experimental Autoimmune Encephalomyelitis (EAE), a model for multiple sclerosis (MS)
Collaboration with:
Marco Prinz, University of Freiburg, Germany
Pablo Blinder, TAU, Israel
Microglia contributions to relapsing remitting EAE
Contributions of perivascular macrophages to EAE.
Modules ensuring microglia quiescence and restoration of the microglia ground state following activation, with a particular focus on the IL-10 axis
Contributions of IL-23 producing monocytes in the generation of pathogenic T cells in EAE
Comparative analysis of HSC-derived engrafted brain macrophages and host microglia in health and disease
The role CX3C chemokine axis in intercellular communication.
Contributions of Dendritic cell, Macrophages and Monocytes Contributions to Gut Health and Inflammatory Bowel Disease (IBD).
Studying Molecular Cues guiding Mononuclear Phagocyte Differentiation
Definition of monocyte development in physiology and pathophysiology (IBD, obesity)
Study of differentiation of monocytes into tissue macrophages in small and large intestine and blood
Studying Interactions of Macrophages with Sympathetic Nerve System
Collaboration with:
Avraham Yaron, Weizmann Institute
