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Professor Emeritus Zvi Kam
Cellular BiophysicsCollaboration with: Benjamin Geiger, John Sedat, David Agard (UCSF)Quantitative analysis of structural features and dynamic changes in cells using microscope imagingHigh throughput high-definition microscopy application in systems cell biologyAdaptive optics methods applied to thick sample imagingCell level informatics
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Prof. Steffen Jung
Brain Macrophage contributions to CNS pathologies, including MS, Alzheimer and Parkinson disease and Multiple sclerosis (MS)Collaboration with: Marco Prinz, University of Freiburg, Germany Pablo Blinder, TAU, Israel Reuven Stein, TAU, Israel Susanne Wolf, MDC, Berlin Soyon Hong, UCL, London, UK Kia Movahedi, VIB, Brussels, BelgiumMicroglia contributions to brain pathologiesContributions of perivascular macrophages to brain pathologiesModules ensuring microglia quiescence and restoration of the microglia ground state following activation, with a particular focus on the IL-10 axisContributions of IL-23 producing monocytes to the generation of pathogenic T cells in the MS model EAEComparative analysis of HSC-derived engrafted brain macrophages and host microglia in health and diseasedevelopment of novel animal models that allow the functional dissection of parenchymal and perivascular brain macrophagesThe role CX3C chemokine axis in intercellular communication.Contributions of Dendritic cell, Macrophages and Monocytes Contributions to Gut Health and Inflammatory Bowel Disease (IBD).Studying Molecular Cues guiding Mononuclear Phagocyte DifferentiationDefinition of monocyte development in physiology and pathophysiology (IBD, obesity)Study of differentiation of monocytes into tissue macrophages in small and large intestine and bloodDefinition of functional conytributions of classical monocyte subsets including neutrophil - and DC- like cells.Studying Interactions of Macrophages with Sympathetic Nerve SystemCollaboration with: Avraham Yaron, Weizmann InstituteCompetitive Fungal commensalism as a therapeutic strategy to curb candidiasisCollaboration with: Neta Shlezinger, HU Bernhard Hube,Leibniz-HKI, Jena, Germany Petra Bacher, University of Kiel, Germany
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Prof. Amnon Horovitz
Linear free energy relationships (LFER) analysis of allosteric transitions in proteins.Analysis of correlated mutations in proteinsCollaboration with: Ron Unger (Bar Ilan University)Allostery in the structure and function of GroEL and CCT chaperonins.Collaboration with: Keith Willison (Imperial College, London); Michal Sharon;Chaperonin-mediated protein folding.Collaboration with: Gilad HaranAnalysis of protein substrate specificity of chaperonins
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Prof. Eran Hornstein
molecular NeurodegenerationRNA and RNA -binding proteins in motor neurons and amyotrophic lateral sclerosis (ALS)Human genetics for neuroscience researchBiomarkers of neurodegenerationMulti-omics and machine learning for biomarkersbiomolecular condensates and stress granules in ALS
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Prof. Avi Hofstein
Research and evaluationCollaboration with: R. MamlokFormative and summative of curriculum units that are developed by the chemistry group and the science for all studentsTeachers' and students' perceptions and attitudes towards science and technology.Non science oriented students' conception of key ideas and concept in chemistryThe development of modules for non-science oriented studentsAnalysis of learning difficulties and misconception in chemistry in the Israeli BagrutDevelopment of argumentation skills in inquiry laboratoriesMisconception regarding bonding and structure of moleculesAssessment of students' perception of the chemistry classroom and laboratory learning environmentHigh school chemistry curriculum development and implementationCollaboration with: Rachel mamlok-Naaman,The development and implementation of text books and teachers' guidePreparation of resources and units for the teaching of Industrial chemistry in Israel.Development of new instructional techniques to teach chemistry in high schools.Inquiry type experiments andThe use of internet for instruction.Development of CAI (computer Assisst Instruction)Development of introductory (basic) modules for a new syllabus in high school chemistry. (Development of modules for non-science oriented students in high schools
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Prof. Gary Hodes
Semiconductor-sensitized nanoporous solar cells and semiconductor film depositionCollaboration with: D. Cahen (WIS)Electrochemical and chemical bath deposition of semiconductor films.Nanocrystalline solar cells; semiconductor-sensitized nanoporous cellsCharge transfer in nanocrystalline films
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