• Picture of Prof. Ed Bayer

    Prof. Ed Bayer

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    Structural and functional aspects of the multi-enzyme cellulosome complex from cellulose-degrading bacteria.
    The cohesin-dockerin couple - Protein-protein interactions that mediate recognition and specificity in cellulosome assembly.
    Cellulose-binding domains as models for protein-sugar interactions.
    Bioinformatics of cellulases and cellulosome components
    Comparative genomics of cellulosome components.
    Structure determination of cellulosome components.
    Enzymology of cellulosomes for conversion of biomass to biofuels
    Designer cellulosomes - Selective engineering of chimaeric cellulosome constructs for nanotechnology.
    Avidin-biotin system - Mutated avidins and streptavidins

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  • Picture of Prof. Zvulun Elazar

    Prof. Zvulun Elazar

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    Molecular mechanisms of autophagy
    Mechanism of autophagosomes biogenesis
    Autophagy and neurodegeneration
    Regulation of autophagy in yeast and mammals
    Mechanism of intracellular protein trafficking
    Regulation of intra-Golgi protein transport

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  • Picture of Prof. Hadassa Degani

    Prof. Hadassa Degani

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    Perfusion and angiogensis in lung cancer: The role of the bronchial and pulmonary vascular network using Fluorescence and magnetic resonance imaging methods
    Molecular magnetic resonance imaging of the estrogen receptor
    Collaboration with:  Professors David Milstein and Joel Sussman, Weizmann Institute
    Synthesis of new, high affinity ligands of the estrogen receptor as probes for molecular imaging
    Structuaral studies (x-ray crystalography and NMR) of the estrogen receptor - targeted ligands complex
    Functional activities and molecular imaging of the new targeted ligands in estrogen receptor positive huaman breast cancer cells
    Mechanisms of lymphatic metastasis in breast cancer; In vivo fluorescence and magnetic resonanc imaging
    Advanced non invasive MRI methods for breast cancer detection and diagnosis ; clinical investigations
    Collaboration with:  Dr. Myra Shapiro, Meir medical Center
    3D Tracking of the mammary tree using diffusion tensor magnetic resonance imaging
    Advanced methods for analysis of dynamic contrast enhanced MRI based on a combined model free and model based method.
    Hyperpolarized magnetic resonance spectroscopy and imaging of cancer metabolism; searching for novel metabolic markers of cancer
    Collaboration with:  Professor Lucio Frydman, Weizmann Institute
    Renal function through sodium grandients; Non-invasive, high resolution sodium MRI.
    Collaboration with:  Dr. Edna Haran, Weizmann Institute
    Estrogen regulation of angiogenesis and perfusion of breast cancer; from molecular mechanisms to functional MRI of the microvascular physiology

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  • Picture of Prof. Michael Elbaum

    Prof. Michael Elbaum

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    Cellular Biophysics and Molecular Transport Machines
    Single-molecule manipulations using optical tweezers.
    Dynamics of DNA uptake into the cell nucleus.
    Structure and function of the nuclear pore complex (with Z. Reich): application of atomic force microscopy and advanced optical spectroscopies.
    Anomalous diffusion in polymer networks and living cells (with R. Granek).
    Organization of forces driving cell movements (with A. Bershadsky): optical force measurements and particle tracking studies; influence of cell biochemistry on biophysical forces.
    Novel surface-patterning lithographies.

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  • Picture of Prof. David Wallach

    Prof. David Wallach

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    Regulation of cell death and tissue damage:
    Proteins involved in the signaling for the cell-killing (apoptotic and necrotic), immunoregulatory, and inflammatory functions of cytokines of the tumor necrosis factor (TNF) family, and in the regulation of these functions.
    In vivo models for the functions of the signaling mechanisms activated by ligands of the TNF family and for their pathological aberrations.
    Natural antagonists to ligands of the TNF family, for protection against the deleterious effects of these cytokines in autoimmune and infectious diseases.
    Regulation of the activity of the NF kappa B transcription factors.
    The caspases, their functions and mechanisms of activation.
    Molecular mechanisms for chronic inflammatory skin diseases.
    Contributions of aberrations in the function of signaling proteins activated by ligands of the TNF family to cancer
    cancer-cells' survival factors

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  • Picture of Prof. Ilan Koren

    Prof. Ilan Koren

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    The twilight zone - convective clouds and their interaction with the free atmosphere
    Collaboration with:  NOAA-ESRL Boulder CO.
    Anthropogenic Effects on Clouds and Precipitation and the Derived Climate Forcing
    Collaboration with:  NASA-GSFC, UMBC
    Cloud microphysics and dynamics
    Cloud classification and cloud textures and morphology

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  • Picture of Prof. Anthony Joseph

    Prof. Anthony Joseph

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    Lie algebras and enveloping algebras, quantum groups. Invariant theory.

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  • Picture of Prof. Idit Shachar

    Prof. Idit Shachar

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    Analyze the pathway regulateing the survival cascades in Chronic lymphocytic leukemia
    Collaboration with:  Dr Michal Haran, Kaplan Medical center
    Follow the mechanisms controlling homing of immune cells in health and disease.
    Determine the mechanisms regulating peripheral B cell maturation and survival in health and disease.

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  • Picture of Prof. Asaph Aharoni

    Prof. Asaph Aharoni

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    Genetic Regulation of Metabolic Pathways and its Co-ordination with Developmental and Stress Response Programs in Plant Biology
    The Primary-Secondary Metabolism Interface
    Regulation of Plant Surface Formation
    Regulation of Secondary Metabolism Associated Metabolic Pathways
    Plant and Yeast Metabolomics
    Riboswitches in Plants: Post Transcriptional Regulators of Metabolic Pathways

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