• Picture of Prof. Michal Sharon

    Prof. Michal Sharon

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    Studying large protein complexes involved in the protein degradation pathway using a novel mass spectrometry approach.
    Developing novel methodological approaches for structural mass spectrometry
    Structure-function relationship of the signalosome complex
    Investigation of the 20S ubiquitin-independent degradation pathway

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  • Picture of Prof. Ehud Shapiro

    Prof. Ehud Shapiro

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    Laying the Biological, Computational and Architectural Foundations for Human Cell Lineage Discovery
    Collaboration with:  E. Shapiro, V. Adalsteinsson, H. Brodi, M. Minden, R. Halaban, C. Klein, M. Meyerson, C. Wu, T. Zukerman, R. Shalom

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  • Picture of Prof. Abraham Shanzer

    Prof. Abraham Shanzer

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    Supramolecular chemistry
    Biomimetic ion binders, diagnostic tools in imaging technologies (fluorescent probes) and potential therapeutic agents. Synthesis, using classical and combinatorial chemistry methods and evaluation.
    Synthesis and properties of molecular based devices; molecular sensors, switches and logical gates for application in nanotechnology.
    Surface bound functional assemblies.

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  • Picture of Dr. Ohad Shamir

    Dr. Ohad Shamir

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    Machine Learning, statistical learning, online learning, learning theory, optimization

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  • Picture of Prof. Adi Shamir

    Prof. Adi Shamir

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    Cryptography, cryptanalysis, electronic money, smartcard security, internet security, complexity theory, the design and analysis of algorithms.
  • Picture of Prof. Zippora Shakked

    Prof. Zippora Shakked

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    Crystal structure and solution studies of DNA oligomers.
    Collaboration with:  Donald Crothers (Yale University)
    DNA regulatory elements
    DNA bending by adenine-thymine tracts
    Structural and biochemical studies of proteins involved in transcriptional regulation.
    The tumor-suppressor protein p53 and its interaction with DNA and the basal transcription machinery
    The leukemia-related RUNX1(AML1) transcription regulator

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  • Prof. Guy Shakhar

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    Dendritic cell behavior:
    The dynamics of antigen sampling, chemokinesis, lymphatic migration
    Antigen presentation by dendritic cells as revealed by intravital imaging
  • Picture of Prof. Yechiel Shai

    Prof. Yechiel Shai

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    Membrane-protein interaction and molecular recognition within the membrane milieu. Implication to the function and structure of membrane proteins.
    Assembly and organization of pore forming toxins and ion channels in membranes: Studies with isolated fragments and intact proteins.
    Molecular mechanism of membrane fusion and its inhibition: Studies with HIV and Sendai Virus.
    Molecular basis for cell selectivity by cytolytic antimicrobial peptides.

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  • Prof. Dan Shahar

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    Physics of electron's spin
    Quantum phase transitions: General transport studies and mesoscopics of the metal-insulator, superconductor-insulator and other transitions.
    Scanning tunneling experiments at ultra-low temperatures
    Fractional and integer quantum Hall effect and related phenomena.
    Experiments on materials at ultra low-temperatures.

  • Prof. Michael Sela

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    An aptamer strategy to target oncogenic signaling in ErbB2 carrying human tumors.
    Collaboration with:  G. Mahlknecht , Y. Yarden G. Mahlknecht
    Synergy of antibodies towards decreasing pancreatic cancer.
    Collaboration with:  R. Maron, B. Schechter, Y. Yarden
    Towards vaccination: Generation of peptide mimotopes specific for anti ErbB-2 monoclonal antibodies.
    Collaboration with:  E. Witsch, Y. Yarden
    Mechanism of action of Copolymer 1 (Copaxone), a therapeutic vaccine against multiple sclerosis.
    Collaboration with:  R. Arnon
    Effective synergism by anti ErbB-2 mAb combinations comprising one mAb against the dimerization site of ErbB-2.
    Collaboration with:  Y. Yarden
    Monoclonal antibodies (mAbs) to ErbB-1 and ErbB-2 receptors and their role in potential anti-tumor strategy.
    Collaboration with:  B. Schechter, Y. Yarden
    Synergistic effects of combinations of mAb against distinct epitopes on EGFR/ErbB-1 and ErbB-2 receptors: accelerated receptor aggregation, down regulation and inhibition of tumor growth.
    Collaboration with:  B. Schechter, Y. Yarden

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