Pages
September 12, 2014
-
Date:21WednesdayDecember 2022Lecture
Israel Quantum Information Theory Day
More information Time 09:30 - 09:30Location The David Lopatie Conference CentreOrganizer The Center for Quantum Science and TechnologyHomepage Contact Abstract Show full text abstract about The Israel Quantum Information Theory day brings together re...» The Israel Quantum Information Theory day brings together researchers, postdoctoral scholars and Ph.D. students from Israel working on the theory of quantum computation and information processing for a day of scientific talks, research discussions and social interaction.
Registration: https://tinyurl.com/2rxsuykb
-
Date:21WednesdayDecember 2022Lecture
Chemical and Biological Physics Guest Seminar
More information Time 15:00 - 15:00Title Quantum simulations and interfaces with Rydberg atomsLocation Perlman Chemical Sciences BuildingLecturer Prof David Petrosyan, Prof. Gershon Kurizki
IESL, FORTH, GreeceOrganizer Department of Chemical and Biological PhysicsContact Abstract Show full text abstract about Atoms in the highly excited Rydberg states possess unique pr...» Atoms in the highly excited Rydberg states possess unique properties, including long lifetimes and huge dipole moments, which facilitate their use in various quantum technology applications. I will discuss recent progress in quantum simulations of many-body physics with strongly-interacting Rydberg atoms and coherent interfaces of Rydberg atoms with superconducting microwave resonators and optical photons, and present some of our results in this research. -
Date:22ThursdayDecember 2022Colloquia
Physics Hybrid Colloquium
More information Time 11:15 - 12:30Title New Astrophysical Puzzles from Studies of Low Mass Galaxies beyond the Milky WayLocation Edna and K.B. Weissman Building of Physical SciencesLecturer Dr. Shani Danieli
Princeton University - New JerseyOrganizer Faculty of PhysicsContact Abstract Show full text abstract about Low-mass galaxies provide an essential testing ground for th...» Low-mass galaxies provide an essential testing ground for theoretical predictions of cosmology. Their number densities, structures, and internal dynamics provide some of the most interesting clues to the nature of dark matter and the theory of galaxy formation on small scales. Recent advances in telescope instrumentation and image analysis techniques have enabled comprehensive investigations of such low surface brightness galaxies. I will present results from novel observations of low-mass galaxies beyond our local galactic neighborhood, uncovering their significant diverseness and new astrophysical puzzles. I will discuss some of the follow-up observations of these extragalactic low-mass galaxies, focusing on their dark matter content and intriguing globular cluster populations. I will conclude by briefly discussing ongoing and future surveys that collectively have the potential to unveil the physics of dark matter. -
Date:25SundayDecember 2022Lecture
Lightning, Biology, and Evolution
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Colin Price
Tel Aviv UniversityOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about Most electrical activity in vertebrates and invertebrates oc...» Most electrical activity in vertebrates and invertebrates occurs at extremely low frequencies (ELF), with characteristic maxima below 50 Hz. The origin of these frequency maxima is unknown and remains a mystery. We propose that over billions of years during the evolutionary history of living organisms on Earth, the natural electromagnetic resonant frequencies in the atmosphere, continuously generated by global lightning activity, provided the background electric fields for the development of cellular electrical activity. In some animals, the electrical spectrum is difficult to differentiate from the natural background atmosphericelectric field produced by lightning. In this talk I will present evidence for the link between the natural ELF fields and those found in many living organisms, including humans. Furthermore, recent experiments show links between the ELF fields and photosynthesis in plants.
-
Date:25SundayDecember 2022Lecture
RNA-Lipid Nanoparticles 2.0: From Gene Silencing to Genome Editing
More information Time 11:00 - 12:00Location Perlman Chemical Sciences BuildingLecturer Prof. Dan Peer
Laboratory of Precision NanoMedicine, Tel Aviv UniversityOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Accumulating work points out relevant genes and signaling pa...» Accumulating work points out relevant genes and signaling pathways hampered in human disorders as potential candidates for therapeutics. Developing nucleic acid-based tools to manipulate gene expression, such as siRNAs, mRNA and genome editing strategies, open up opportunities for personalized medicine. Yet, although major progress was achieved in developing RNA targeted delivery carriers, mainly by utilizing monoclonal antibodies (mAbs) for targeting, their clinical translation has not occurred. In part because of massive development and production requirements and high batch-to-batch variability of current technologies, which relies on chemical conjugation. Here we present a self-assembled modular platform that enables to construct theoretically unlimited repertoire of RNA targeted carriers. The platform self-assembly is based on a membrane-anchored lipoprotein, incorporated into RNA-loaded novel, unique lipid nanoparticles that interact with the antibody Fc domain. We show that a simple switch of 8 different mAbs, redirects specific uptake of siRNAs by diverse leukocyte subsets in vivo. The platform therapeutic potential is demonstrated in an inflammatory bowel disease model, by targeting colon macrophages to reduce inflammatory symptoms, and in Mantle Cell Lymphoma xenograft model, by targeting cancer cells to induce cell death and improve survival. In addition, I will discuss novel approach for delivering modified mRNA to specific cell types in vivo utilizing this platform. I will also share some data on mRNA vaccines for COVID19 and Finally, I will share new data showing very high efficiency genome editing in glioma and metastatic ovarian cancer. This modular delivery platform can serve as a milestone in turning precision medicine feasible.
-
Date:26MondayDecember 2022Colloquia
One hundred years of electrified interfaces: What’s new with the theories of Debye and Onsager?
More information Time 11:00 - 12:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. David Andelman
School of Physics, Tel Aviv UniversityOrganizer Faculty of ChemistryHomepage Contact Abstract Show full text abstract about The Poisson-Boltzmann theory stems from the pioneering works...» The Poisson-Boltzmann theory stems from the pioneering works of Debye and Onsager and is considered even today as the benchmark of ionic solutions and electrified interfaces. It has been instrumental during the last century in predicting charge distributions and interactions between charged surfaces, membranes, electrodes as well as macromolecules and colloids. The electrostatic model of charged fluids, on which the Poisson-Boltzmann description rests and its statistical mechanical consequences have been scrutinized in great detail. Much less, however, is understood about its probable shortcomings when dealing with various aspects of real physical, chemical, and biological systems. After reviewing the Poisson-Boltzmann theory, I will discuss several extensions and modifications to the seminal works of Debye and Onsager as applied to ions and macromolecules in confined geometries. These novel ideas include the effect of dipolar solvent molecules, finite size of ions, ionic specificity, surface tension, and conductivity of concentrated ionic solutions. -
Date:27TuesdayDecember 2022Conference
SAMPL 2022 Workshop - Bringing Science, Technology and Medicine Together
More information Time 08:00 - 18:00Location The David Lopatie Conference CentreChairperson Yonina Eldar -
Date:27TuesdayDecember 2022Lecture
iSCAR seminar
More information Time 09:00 - 10:00Location Max and Lillian Candiotty BuildingLecturer Prof. Yossi Buganim
"The different paths governing the creation of artificial embryo stem cells"Organizer Department of Immunology and Regenerative BiologyContact -
Date:27TuesdayDecember 2022Lecture
ATFS-1 coordinates mitochondrial network expansion and peroxisome biogenesis in the model organism Caenorhabditis elegans
More information Time 10:00 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Tomer Shpika
Dept. of Molecular, Cell and Cancer Biology. University of Massachusetts Medical SchoolOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about As organisms develop, individual cells generate mitochondria...» As organisms develop, individual cells generate mitochondria and peroxisomes to fulfill their physiological requirements. A decline, or dysfunction in these organelles is associated with ageing and a vast array of clinical manifestations including metabolic disorders and neurodegenerative diseases. Despite this, it is unknown how mitochondrial network expansion and peroxisome biogenesis is scaled to cell growth, and how cells maintain the organelles’ function during stress. The mitochondrial unfolded protein response (UPRmt) is a protective signaling pathway mediated by the transcription factor ATFS-1. Using genetic and biochemical approaches in the model organism Caenorhabditis elegans we demonstrate that ATFS-1 mediates an adaptable mitochondrial network expansion program and a peroxisomal retrograde response that is active throughout normal development. These findings as well as the therapeutic potential and future directions of my studies will be presented. -
Date:27TuesdayDecember 2022Lecture
“Intelligentsia of Nano-Architected Hierarchical Materials”
More information Time 11:15 - 12:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Julia Greer
California Institute of TechnologyOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Creation of reconfigurable and multi-functional materials ca...» Creation of reconfigurable and multi-functional materials can be achieved by incorporating architecture into material design. In our research, we design and fabricate three-dimensional (3D) nano-architected materials that can exhibit superior and often tunable thermal, photonic, electrochemical, biochemical, and mechanical properties at extremely low mass densities (lighter than aerogels), which renders them useful and enabling in technological applications. Dominant properties of such meta-materials are driven by their multi-scale nature: from characteristic material microstructure (atoms) to individual constituents (nanometers) to structural components (microns) to overall architectures (millimeters and above).
Our research is focused on fabrication and synthesis of nano- and micro-architected materials using 3D lithography, nanofabrication, and additive manufacturing (AM) techniques, as well as on investigating their mechanical, biochemical, electrochemical, electromechanical, and thermal properties as a function of architecture, constituent materials, and microstructural detail. Additive manufacturing (AM) represents a set of processes that fabricate complex 3D structures using a layer-by-layer approach, with some advanced methods attaining nanometer resolution and the creation of unique, multifunctional materials and shapes derived from a photoinitiation-based chemical reaction of custom-synthesized resins and thermal post-processing. A type of AM, vat polymerization, has allowed for using hydrogels as precursors, and exploiting novel material properties, especially those that arise at the nano-scale and do not occur in conventional materials. The focus of this talk is on additive manufacturing via vat polymerization and function-containing chemical synthesis to create 3D nano- and micro-architected metals, ceramics, multifunctional metal oxides (nano-photonics, photocatalytic, piezoelectric, etc.), and metal-containing polymer complexes, etc., as well as demonstrate their potential in some real-use biomedical, protective, and sensing applications. I will describe how the choice of architecture, material, and external stimulus can elicit stimulus-responsive, reconfigurable, and multifunctional response -
Date:27TuesdayDecember 2022Lecture
Biosynthesis of Plant Natural Products: from the Colours of Beet to Defences in Wheat
More information Time 11:30 - 12:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Guy Polturak
John Innes CentreOrganizer Department of Plant and Environmental SciencesContact Abstract Show full text abstract about Plants produce a vast range of specialized metabolites that ...» Plants produce a vast range of specialized metabolites that serve various roles, including mediating interactions with their immediate environments and providing defence against (a)biotic stresses. The ‘omics era’ has brought a new golden age for plant specialized metabolism research, vastly accelerating the discovery of novel metabolites and our understanding of their biosynthesis, roles and regulation. Two studies exemplifying omics-driven discovery of metabolic pathways, in beet and in wheat, will be presented:
1. Betalains are red-violet and yellow pigments restricted to order Caryophyllales, which have attracted interest due to their health-promoting properties and use as food colorants. Transcriptomics-led discovery of enzymes catalyzing the last unknown step in betalain biosynthesis in red beet enabled us to heterologously produce these pigments in plants and microbes, providing a valuable platform for studying their in-planta roles and enabling their subsequent utilization as reporter genes and plant transformation markers.
2. Wheat is one of the most widely grown crops in the world but is susceptible to numerous pests and pathogens, leading to major annual losses. Despite its agricultural importance, current knowledge of wheat chemical defenses remains very limited. Using a genome mining approach we uncovered six previously unknown pathogen-induced metabolic pathways in hexaploid bread wheat, which produce a diverse set of molecules and are encoded by biosynthetic gene clusters. Discovery and characterization of these cluster-encoded metabolic pathways provides key insights into the molecular basis of biotic stress responses in wheat, thus opening new potential avenues for improvement of this major food crop.
-
Date:27TuesdayDecember 2022Lecture
Bird nests and nesting behavior
More information Time 15:30 - 16:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Uri Moran Organizer Department of Plant and Environmental SciencesContact -
Date:29ThursdayDecember 202230FridayDecember 2022Lecture
Hanukkah STAR - mini workshop 2022
More information Time All dayLocation Jacob Ziskind BuildingOrganizer Faculty of Mathematics and Computer ScienceHomepage Contact -
Date:29ThursdayDecember 2022Colloquia
physics Hybrid Colloquium
More information Time 11:15 - 12:30Title Tba..Location Edna and K.B. Weissman Building of Physical SciencesLecturer Ahmed Almheiri Organizer Faculty of PhysicsContact Abstract Show full text abstract about Tba.. ...» Tba.. -
Date:29ThursdayDecember 2022Lecture
From Stem Cells to Synthetic Embryos
More information Time 13:00 - 14:00Location Gerhard M.J. Schmidt Lecture HallLecturer Dr. Noa Novershtern
Department of Molecular GeneticsContact Abstract Show full text abstract about Gastrulation, the early stage of embryonic development in wh...» Gastrulation, the early stage of embryonic development in which the organs are starting to form, is an elusive stage, which is hard to investigate because its access in mammals is limited. In this talk I will describe how our lab was able to grow mouse embryos outside the uterus, and how our work on stem cells has ultimately enabled us to grow synthetic embryos, generated from stem cells without egg and sperm, thus allowing us a window to mammalian gastrulation. -
Date:29ThursdayDecember 2022Academic Events
Scientific Council Meeting
More information Time 14:00 - 16:00Location The David Lopatie Conference CentreContact -
Date:29ThursdayDecember 2022Lecture
Computational approaches for identifying genomic and metabolic predictors of cancer patient response to immune checkpoint blockade therapy
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Dr. Keren Yizhak
Department of Cell Biology and Cancer Science, Faculty of Medicine, TechnionOrganizer Dwek Institute for Cancer Therapy ResearchContact -
Date:29ThursdayDecember 2022Lecture
FIRST PES Student Seminar
More information Time 15:00 - 16:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Ofir Aharon Kuperman & Ben Labbel& Sam Lovat
Ofir Aharon Kuperman | PhD student- Natalio Lab Ben Labbel | PhD student- Vardi Lab Sam Lovat | Visiting student Lovat | Visiting student- Milo LabOrganizer Department of Plant and Environmental SciencesContact -
Date:01SundayJanuary 2023Lecture
Special Guest Seminar
More information Time 10:00 - 11:00Title Deep learning for protein-RNA interactionsLocation Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Yaron Orenstein Organizer Department of Molecular GeneticsContact -
Date:01SundayJanuary 2023Lecture
TBA
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Yishai Weinstein
Bar Ilan UnivrsityOrganizer Department of Earth and Planetary SciencesContact
