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January 01, 2015
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Date:16TuesdayMay 2023Lecture
Special Guest Seminar
More information Time 15:00 - 16:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Alexander Meissner & Prof. Paul Tesar Organizer Department of Molecular GeneticsContact -
Date:16TuesdayMay 2023Lecture
Special Guest Seminar
More information Time 15:00 - 15:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Alexander Meissner & Prof. Paul Tesar Organizer Department of Molecular GeneticsContact -
Date:17WednesdayMay 2023Lecture
Factors determining the early steps in the disease initiation of myeloproliferative neoplasms by the JAK2-mutated hematopoietic stem cell
More information Time 10:00 - 11:00Location Ullmann Building of Life SciencesLecturer Prof. Dr. Radek C. Skoda
Department of Biomedicine, University of Basel, SwitzerlandOrganizer Department of Molecular Cell BiologyContact -
Date:17WednesdayMay 2023Lecture
CALR mutated myeloproliferative neoplasms: pathogenesis and targeted therapies
More information Time 11:00 - 12:00Location Ullmann Building of Life SciencesLecturer Assistant-Prof Robert Kralovics, Ph.D
Department of Laboratory Medicine, Medical University of Vienna, AustriaOrganizer Department of Molecular Cell BiologyContact -
Date:18ThursdayMay 2023Lecture
Non-invasive Methods for Extracting Microstructural Information from Human Tissues: Implementation in a Clinical MRI Scanner
More information Time 09:30 - 10:30Location Gerhard M.J. Schmidt Lecture HallLecturer Ana Naamat
Medical Physics Department, Bariloche Atomic CenterOrganizer Clore Institute for High-Field Magnetic Resonance Imaging and SpectroscopyContact Abstract Show full text abstract about Extracting quantitative information about tissue microstruct...» Extracting quantitative information about tissue microstructure using non-invasive methods is an exceptional challenge in understanding disease mechanisms and enabling early diagnosis of pathologies. Magnetic Resonance Imaging (MRI) is a promising and widely used technique to achieve this goal, but it still provides low resolution to reveal details of the microstructure. Recently, we have developed methods to produce images with quantitative information about the microstructure based on selective probing of spin dephasing induced by molecular diffusion restriction in cavities of the tissue microstructure [1-3]. The feasibility of the theoretical method has been demonstrated so far by first-principles experiments and simulations on typical size distributions of white matter in the mouse brain [3]. As a next step towards practical implementation, we have implemented this method in clinical scanners [4]. In this work, I present the challenges and preliminary results of this implementation in both phantoms and human volunteers. These results open up a new avenue for MRI to advance in extracting quantitative, and fast microstructural information from images.
[1] A. Zwick, D. Sueter, G. Kurizki, G. A. Álvarez, Phys. Rev. Applied 14, 024088, (2020).
[2] M. Capiglioni, A. Zwick, P. Jiménez, G. A. Álvarez. Proc. Intl. Soc. Mag. Reson. Med. 29, 2036 (2021)
[3] M. Capiglioni, A. Zwick, P. Jiménez and G. A. Álvarez, Phys. Rev. Applied 15, 014045 (2021).
[4] E. Saidman, A. Zwick, S. Tambalo, T. Feiweier, J. Jovicich, G. A. Álvarez. Proc. Intl. Soc. Mag. Reson. Med. (2023)
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Date:18ThursdayMay 2023Colloquia
Physics Colloquium
More information Time 11:15 - 12:30Title TBA...Location Edna and K.B. Weissman Building of Physical SciencesLecturer Prof. Eva Andre Organizer Faculty of PhysicsContact Abstract Show full text abstract about TBA... ...» TBA... -
Date:18ThursdayMay 2023Lecture
Stromal and immune plasticity shape the metastatic microenvironment
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Neta Erez
The Department of Pathology, Faculty of Medicine, Tel Aviv UniversityOrganizer Dwek Institute for Cancer Therapy ResearchContact -
Date:20SaturdayMay 202324WednesdayMay 2023Conference
New Frontiers in Cardiac and Vascular Biology
More information Time 08:00 - 08:00Location The David Lopatie Conference CentreChairperson Karina YanivOrganizer Department of Physics of Complex SystemsHomepage -
Date:21SundayMay 2023Lecture
“ Programmatic and Deep Learning Analysis Pipelines for 4D-STEM Materials Science Experiments”
More information Time 11:00 - 12:00Location Gerhard M.J. Schmidt Lecture HallLecturer Dr. Colin Ophus
Lawrence Berkeley National Laboratory, BerkeleyOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Scanning transmission electron microscopy (STEM) is one of t...» Scanning transmission electron microscopy (STEM) is one of the most popular materials science methods to characterize the structure and chemistry of nanoscale samples, owing to its high resolution and many flexible operating modes. In a conventional STEM experiment, we focus the electron beam down to a probe from nanometer to sub-angstrom scale, and scan it over the sample surface while recording diffracted signals which are transmitted through the specimen. STEM can also record analytic signals such as x-rays generated by the electron beam to measure composition, or energy loss of the transmitted electrons to probe the electronic structure of samples. Conventional STEM imaging detectors experiments produce only a few intensity values at each probe position, but modern high-speed detectors allow us to measure a full 2D diffraction pattern, over a grid of 2D probe positions, forming a four dimensional (4D)-STEM dataset. These 4D-STEM datasets record information about the local phase, orientation, deformation, and other parameters, for both crystalline and amorphous materials. 4D-STEM datasets can contain millions of images and therefore require highly automated and robust software codes to extract the target properties. In this talk, I will introduce our open source py4DSTEM analysis toolkit, and show how we use these codes to perform data-intensive studies of material properties over functional length scales. I will also demonstrate some applications of modern machine learning tools, to perform measurements on electron diffraction patterns where property signals have been scrambled by multiple scattering of the electron beam.
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Date:21SundayMay 2023Lecture
Determining past lake temperatures in saline lake systems using fluid inclusions: an example from the Dead Sea
More information Time 11:00 - 12:00Location Sussman Family Building for Environmental SciencesLecturer Niels Brall
The Hebrew University of JerusalemOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about In recent decades, various temperature proxies have been dev...» In recent decades, various temperature proxies have been developed and further established in the scientific community, at both low and high accuracy, however, not every method can be applied without restriction to all minerals or rocks. Evaporitic rocks, for example, are abundant chemical sediments at the Earth's surface that are deposited from supersaturated brines in marine, terrestrial, and lacustrine environments. Halite is the most abundant rock-forming mineral in this group, which during crystal formation entraps tiny water droplets (fluid inclusions, FIs) that store the chemical composition of the parent brine at a specific pressure-temperature dependent density. Such FIs are therefore excellent records of the original physicochemical conditions of the source brine.
Brillouin spectroscopy (BS) is a novel laser-based technique that uses density fluctuations in FIs to directly measure entrapment temperatures and thus the initial brine temperature during crystal growth. In this seminar, the BS method will be introduced and two application cases will be presented using salt layers from the Dead Sea which were deposited during two interglacial periods. In addition to the basic principles, both the recommended sampling strategy and pitfalls along with associated limitations will be presented.
The conclusion will be that the salt layers commonly deposited in the Dead Sea basin consist of two types that formed preferentially in summer (coarse-grained crystals) and winter (fine-grained crystals), which is mainly controlled by the degree of salt saturation of the lake water. Furthermore, it will be shown how (1) lake bottom temperatures have fluctuated seasonally (summer/winter), and that (2) paleo temperature trends can be reconstructed for an entire halite layer that was deposited during holomictic periods in the Dead Sea basin. This method is particularly promising for evaporites that formed near the surface if the material has not been affected by external processes such as tectonic burial/uplift, erosion, or mineral replacement.
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Date:21SundayMay 2023Lecture
Illuminating neural computations with structured light and sound wavefronts
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Shy Shoham
Neural Interface Engineering lab, NYUOrganizer Department of Brain SciencesContact -
Date:21SundayMay 2023Lecture
PhD Thesis Defense by Omer Goldman (Ayelet Erez Lab)
More information Time 13:00 - 13:00Title Non-liver cancers rewire liver metabolism in the hostLocation Max and Lillian Candiotty BuildingLecturer Omer Goldman (Ayelet Erez Lab) Organizer Department of Molecular Cell BiologyContact -
Date:21SundayMay 2023Lecture
Brown Fat: From Basic Cell Biology to Human Health and Disease
More information Time 15:00 - 16:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Paul Cohen
The Rockefeller University, NY, USAContact -
Date:22MondayMay 2023Colloquia
Ultrafast processes and the challenge of decoherence
More information Time 11:00 - 12:15Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Eberhard K. U. Gross
Fritz Haber Center for Molecular Dynamics, HUJI, JerusalemOrganizer Faculty of ChemistryHomepage Contact Abstract Show full text abstract about A prominent goal of present-day condensed-matter physics is ...» A prominent goal of present-day condensed-matter physics is the design of electronic devices with ever faster switching times. As an example I will present the optically induced spin transfer between magnetic sublattices, the so-called OISTR effect, which allows the switching of magnetic textures on the scale of a femto-second or less. This effect was first predicted with real-time TDDFT and later confirmed in many experiments. To create from this effect a real-world device on has to face the problem of decoherence, i.e. the phenomenon that quantum systems tend to lose their quantumness due to interactions with the environment. For electrons, the principal source of decoherence is the non-adiabatic interaction with nuclear degrees of freedom, i.e. with an “environment” that cannot be removed. In fact, the paradigm of electronic-structure theory where electrons move in the static Coulomb potential of clamped nuclei, while useful in the ground state, is an idealization hardly ever satisfied in dynamical processes. Non-adiabaticity, i.e. effects of the coupled motion of electrons and nuclei beyond the Born-Oppenheimer approximation are found everywhere. In this lecture, the exact factorization will be presented as a universal approach to understand and, ultimately, control non-adiabatic effects, in particular decoherence, from an ab-initio perspective. -
Date:23TuesdayMay 2023Lecture
Exploring sex-specific regulation of aging and health
More information Time 10:00 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Itamar Harel
Dept. of Genetics, HUJIOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Bio: Experimental biology of vertebrate aging and age-relate...» Bio: Experimental biology of vertebrate aging and age-related diseases: http://harel-lab.com/
Itamar Harel received his PhD in developmental biology at the Weizmann Institute of Science, and then trained in aging research at Stanford University. In 2018 he joined the Department of Genetics at the Hebrew University as Assistant Professor. The Harel lab is exploring fundamental questions in aging biology, such as why is aging such a strong driver of disease? To address a major challenge in aging research, Itamar has developed a comprehensive genetic platform for rapid exploration of aging and disease in a naturally short-lived vertebrate. The findings by the Harel lab have clinical implications for developing new strategies for modeling and treating age-related diseases, and for developing pro-longevity interventions. -
Date:23TuesdayMay 2023Lecture
Bacterial lag phase shortening is triggered by methyl groups – a primer for phototroph-heterotroph interactions?
More information Time 11:30 - 12:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Martin Sperfeld
Segev LabOrganizer Department of Plant and Environmental SciencesContact -
Date:23TuesdayMay 2023Lecture
The neurocircuit underlying social approach and avoidance behavior
More information Time 12:30 - 13:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Camilla Bellone
Dept of Basic Neurosciences Faculty of Medicine University of GenevaOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The ability to approach or avoid conspecifics is essential f...» The ability to approach or avoid conspecifics is essential for survival in many species, and the nature of the social interaction often determines it. Positive or rewarding interactions with conspecifics lead individuals to approach them, while aversive or threatening interactions lead individuals to avoid them. The rewarding or aversive nature of these interactions is defined as social valence. I will discuss the neuronal circuits and mechanisms underlying social valance encoding.
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Date:23TuesdayMay 2023Lecture
Advances of Liquid Biopsy Diagnostics and Structural Models in the Development of Data-Driven AI in Future Hospitals
More information Time 14:00 - 15:00Location Gerhard M.J. Schmidt Lecture HallLecturer Dr. Milana Frenkel-Morgenstern
Azrieli Faculty of Medicine Bar-Ilan UniversityOrganizer Department of Chemical and Structural BiologyContact -
Date:24WednesdayMay 2023Lecture
Simplifying Multicolor Panel Construction for Conventional and Spectral Flow Cytometers
More information Time 10:00 - 11:00Location Ullmann Building of Life SciencesLecturer Dr. Jiri Sinkora
Application Specialist at BDOrganizer Department of Life Sciences Core FacilitiesContact -
Date:24WednesdayMay 2023Lecture
Machine Learning and Statistics Seminar
More information Time 11:15 - 12:30Title Cycle-edge message passing for group and non-group synchronizationLocation Jacob Ziskind BuildingLecturer Prof. Gilad Lerman
U. MinnesotaOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about The general synchronization problem asks to recover states o...» The general synchronization problem asks to recover states of objects from their corrupted relative measurements. When the states are represented by group elements (e.g. 3-D rotations or permutations) this problem is known as group synchronization. In several applications, the algebraic structure of the states is more complicated, for example, the states can be represented by partial permutations. The synchronization problem has many applications, in particular, to structure-from-motion (SfM), where one needs to estimate the 3D structure of a scene from a set of its projected 2D images. I will first describe a general framework for group synchronization, the Cycle-Edge Message Passing (CEMP), and then explain its generalization to non groups, by exemplifying the case of partial permutation synchronization. I will emphasize mathematical difficulties, review some mathematical guarantees for the proposed methods and also demonstrate an application. This is a joint work with Shaohan Li and Yunpeng Shi.
