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June 06, 2016
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Date:11ThursdaySeptember 2025Lecture
Department of Molecular Genetics Special Guest Seminar
More information Time 10:00 - 11:00Title Functional characterization and therapeutic targeting of gene regulatory elementsLocation Botnar AuditoriumLecturer Nadav Ahituv Contact Abstract Show full text abstract about Nucleotide variation in gene regulatory elements is a major ...» Nucleotide variation in gene regulatory elements is a major determinant of phenotypes including morphological diversity between species, human variation and human disease. Despite continual progress in the cataloging of these elements, little is known about the code and grammatical rules that govern their function. Deciphering the code and their grammatical rules will enable high-resolution mapping of regulatory elements, accurate interpretation of nucleotide variation within them and the design of sequences that can deliver molecules for therapeutic purposes. To this end, we are using massively parallel reporter assays (MPRAs), including capture-C based MPRAs, to simultaneously test the activity of thousands of gene regulatory elements and their target promoter in parallel. Regulatory elements can also serve as therapeutic targets. By targeting regulatory elements via CRISPR activation (CRISPRa), we show that they can be used to rescue a variety of haploinsufficient diseases (having -50% dosage reduction due to having only one functional allele). In addition, utilizing CRISPRa to engineer adipocytes and adipose organoids to outcompete tumors for nutrients, we show that they can be used as a novel cancer therapy, termed Adipose Manipulation Transplantation (AMT). -
Date:15MondaySeptember 2025Lecture
Functional genomic approaches to cancer
More information Time 11:00 - 12:00Location Candiotty
AuditoriumLecturer Prof. Todd Golub Organizer Dwek Institute for Cancer Therapy Research -
Date:16TuesdaySeptember 202518ThursdaySeptember 2025Academic Events
Minerva Annual meeting 2025
More information Time All dayContact -
Date:16TuesdaySeptember 202518ThursdaySeptember 2025Conference
Minerva 2025
More information Time 08:00 - 08:00Title Minerva 2025Chairperson Igal NevoContact -
Date:16TuesdaySeptember 2025Lecture
EPS AI discussion (via zoom): Advances in Inferring Air Quality from Global to Local Scales using Deep Learning Constrained by Satellite Remote Sensing and Modeling
More information Time 16:00 - 17:00Location via zoomLecturer Randall Martin Organizer Department of Earth and Planetary SciencesAbstract Show full text abstract about Human exposure to atmospheric aerosols is increasingly recog...» Human exposure to atmospheric aerosols is increasingly recognized as the leading global environmental determinant of health and longevity. However, ground-based monitoring remains sparse in many regions of the world. Deep learning offers immense potential to advance understanding of air quality by leveraging large satellite remote sensing datasets. However, the spatial heterogeneity and autocorrelation of ground-based measurements pose challenges to the training and testing of algorithms for true out of sample prediction. Thus, algorithms benefit from additional process-based constraints from a chemical transport model and targeted ground-based measurements of aerosol chemical composition. This talk will highlight recent advances in applying deep learning by building on satellite remote sensing, global modeling, and ground-based measurements to improve understanding of air quality and planetary health from global toward urban scales -
Date:17WednesdaySeptember 2025Lecture
2025-2026 Spotlight on Science Seminar
More information Time 12:30 - 14:00Title Unveiling the Invisible: XRM/Micro-CT and its ApplicationsLocation Arthur and Rochelle Belfer Building for Biomedical Research
Botnar AuditoriumContact -
Date:18ThursdaySeptember 2025Lecture
Geometric Functional Analysis and Probability Seminar
More information Time 13:30 - 14:30Title Curvature-Dimension for Autonomous LagrangiansLocation Jacob Ziskind Building
Room 155 - חדר 155Lecturer Rotem Assouline
WISOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about In this talk, we will demonstrate how the celebrated connect...» In this talk, we will demonstrate how the celebrated connection between Ricci curvature, optimal transport, and geometric inequalities such as the Brunn-Minkowski inequality, extends to the setting of general Lagrangians on weighted manifolds. As examples, we will consider classical (mechanical and electromagnetic) Lagrangians on Riemannian manifolds. In particular, we will state a generalization of the horocyclic Brunn-Minkowski inequality to complex hyperbolic space of arbitrary dimension, and a new Brunn-Minkowski inequality for contact magnetic geodesics on odd-dimensional spheres. -
Date:18ThursdaySeptember 2025Lecture
A Deep Dive into Immune Tolerance
More information Time 14:00 - 15:00Location Max and Lillian Candiotty Building
AuditoriumLecturer Dr. Ranit Kedmi Organizer Dwek Institute for Cancer Therapy Research -
Date:30TuesdaySeptember 2025Lecture
The Clore Center for Biological Physics
More information Time 10:15 - 11:15Title Comparative metagenomics using microbiome-wide sequence graphsLocation Nella and Leon Benoziyo Physics LibraryLecturer Dr. Tal Korem
refreshments will be served at 9:45Contact Abstract Show full text abstract about Identifying microbial genomic factors that underlie importan...» Identifying microbial genomic factors that underlie important phenotypes is a key goal of microbiological and microbiome research. Current approaches for this goal, however, cannot tap into the wealth of genomic information in a systematic manner, particularly in microbes that are not well-characterized. I will present a new conceptual and methodological approach for analyzing microbial communities using multi-sample sequence graphs. Our results demonstrate that this approach captures sequence and variant information more accurately than traditional approaches, provides graphs that are more suitable for comparative analyses, and is computationally tractable. I will end by demonstrating an application for predicting gut colonization trajectories of Vancomycin-resistant Enterococcus. Overall, our results underscore the value of graph-based frameworks for comparative metagenomic analyses. -
Date:01WednesdayOctober 2025Lecture
students seminar series- Azrieli
More information Time 10:30 - 12:30Location Camelia Botnar BuildingContact -
Date:15WednesdayOctober 2025Lecture
Foundations of Computer Science Seminar
More information Time 11:15 - 12:30Title ReLU networks and polytopesLocation Jacob Ziskind BuildingLecturer Amir Yehudayof
Technion and the University of CopenhagenOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about ReLU networks are a standard example of neural networks. We ...» ReLU networks are a standard example of neural networks. We will discuss the expressivity of neural networks, focusing on their depth. The plan is to start with a general introduction and a survey of basic results, including the duality between ReLU networks and a model for constructing polytopes. We will then discuss polytopes and discuss how their properties can help us understand the depth of neural networks.
Based on joint works with Bakaev, Brunck, Hertrich and Stade. -
Date:15WednesdayOctober 2025Lecture
Machine Learning and Statistics Seminar
More information Time 11:15 - 12:15Title ReLU networks and polytopesLocation Jacob Ziskind BuildingLecturer Amir Yehudayof
Technion and the University of CopenhagenOrganizer Department of Computer Science and Applied MathematicsContact Abstract Show full text abstract about ReLU networks are a standard example of neural networks. We ...» ReLU networks are a standard example of neural networks. We will discuss the expressivity of neural networks, focusing on their depth. The plan is to start with a general introduction and a survey of basic results, including the duality between ReLU networks and a model for constructing polytopes. We will then discuss polytopes and discuss how their properties can help us understand the depth of neural networks.
Based on joint works with Bakaev, Brunck, Hertrich and Stade. -
Date:16ThursdayOctober 2025Conference
Affinity and Biorecognition- Meir Wilchek 90th Birthday
More information Time 08:00 - 08:00Title Affinity and Biorecognition- Meir Wilchek 90th BirthdayLocation The David Lopatie Conference CentreChairperson Ronen AlonContact -
Date:19SundayOctober 2025Lecture
Special Guest Seminar
More information Time 11:00 - 12:00Title Dissecting Alzheimer’s Disease Risk Genes: Insights from Immune Genetic PerturbationsLocation Max and Lillian Candiotty Building
AuditoriumLecturer Dr. Neta Rosenzweig Organizer Department of Molecular Neuroscience , Department of Immunology and Regenerative BiologyContact -
Date:20MondayOctober 2025Lecture
The Clore Center for Biological Physics
More information Time 13:15 - 14:15Title Fluctuations and large deviations of the current in diffusive systemsLocation Nella and Leon Benoziyo Physics LibraryLecturer Professor Bernard Derrida
Refreshments at 12:45Contact Abstract Show full text abstract about For diffusive systems (i.e., systems which satisfy ...» For diffusive systems (i.e., systems which satisfy Fourier's law or Fick's law) maintained in a non-equiilibrium steady state by contact with two heat baths or two reservoirs, the macroscopic fluctuation theory developed over the last 25 years has become a major tool to calculate the fluctuations and the large deviation function of the heat or of the particle currents. After a review of the main achievements of the theory, I will try to list some open issues. In particular, although the theory predicts the same large deviationfunction of the current in all dimensions, numerical calculations exhibit some small discrepancy in space dimension d > 2.This talk will try to explain the origin of these discrepancies.work in collaboration with Thierry Bodineau -
Date:21TuesdayOctober 2025Lecture
Weizmann Ornithology monthly lecture
More information Time 14:10 - 15:30Location Benoziyo biochemistry
591C between eleevatorsLecturer Uri Moran
Bird club meetingContact -
Date:22WednesdayOctober 2025Lecture
Developmental Club Series 2025-26
More information Time 10:00 - 11:00Title Signaling Induced Plasticity in Mouse Naive ESCs Enables Direct and Transgene-Free Generation of Synthetic EmbryosLocation Botnar auditoriumLecturer Dr. Jacob Hanna -
Date:22WednesdayOctober 2025Lecture
2025-2026 Spotlight on Science Seminar Series - Dr. Xiao-Meng Sui (Department of Chemical Research Support)
More information Time 12:30 - 14:00Title Unveiling the Invisible: XRM/Micro-CT and its ApplicationsLocation Gerhard M.J. Schmidt Lecture HallLecturer Xiaomeng Sui Contact Abstract Show full text abstract about X-ray microscopy (XRM) or X-ray micro computed tomography (m...» X-ray microscopy (XRM) or X-ray micro computed tomography (micro-CT) is a non-destructive and noninvasive imaging technique that uses X-rays to characterize cross-sectional and three-dimensional internal structures. While CT was initially developed for medical imaging, the need for higher resolution and the advancement of technology led to the creation of micro-CT in the early 1980s, specifically for evaluating material structure and other applications requiring higher detail.In this talk, I will introduce XRM, its brief history and basic principles, along with some examples of applications. -
Date:23ThursdayOctober 2025Lecture
In vivo targeted and deterministic single cell cancer induction
More information Time 14:00 - 15:00Location Candiotty
AuditoriumLecturer Prof. David Bensimon Organizer Dwek Institute for Cancer Therapy Research -
Date:23ThursdayOctober 2025Lecture
Development of Fluorescence- and Bioluminescence-Based Methods to Monitor and Modulate Sphingolipid Metabolism in Living Cells
More information Time 14:00 - 15:00Location Perlman Chemical Sciences Building
404Lecturer Prof. Christoph Arenz Organizer Department of Chemical and Structural Biology