This lecture focuses on the challenging, understanding-based design, creation,and realization of new materials combinations for unconventional, flexible/bendable/stretchable electronic circuitry. Fabrication methodologies includehigh-throughput, large-area, high-resolution patterning techniques. Materialsdesign issues for next-generation electronics and sensors build upon the abovefindings and include: 1. Designing mechanical agility into semiconducting molecularand polymeric electronics, 2. Harmonizing electron/hole and ion conduction foriontronic circuitry, 3. Hybridizing organic and oxide electronics. In all areas, thesymbiosis of green materials synthesis, computational modeling and simulation,and materials characterization over multiple length and time scales are centralto progress.