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Dr. Yohai Kaspi
Geophysical fluid dynamicsAtmospheric dynamics on Earth and other planetsStorm track dynamicsGeostrophic turbulenceSuperrotationClimate dynamicsPlanetary interiorsGravitational signature of internal dynamics on giant planetsJets on giant planetsInternal tidesThe Juno mission to Jupiter
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Prof. Avi Ben-Nun
Neuroimmunology, pathogenic autoimmunity, myelin/neuronal repair, and treatment of autoimmune diseases in central nervous system (CNS):T-cell pathogenesis and regulation in autoimmune diseases of the CNS.Effects of functional epistasis between HLA class-II alleles on genetic predisposition to multiple sclerosis (MS) in humanized HLA-Tg mice and MS patients.Defining major pathogenic MS-related myelin/neuronal epitopes in HLA-transgenic (Tg) mice.Antigen-based immune-specific approaches to therapy (and mechanisms) of MS and other T-cell mediated autoimmune diseases.Myelin/neuronal repair by adult neural stem cells in mice with chronic MS-like disease.
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Dr. Sarel-Jacob Fleishman
Computational design of protein functionComputational design and experimental characterization via in vitro evolution of high affinity interactionsThe role of multispecificity in small signaling networksSpecificity and multispecificity in membrane-protein interactionsDesign of membrane-protein interactions
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Prof. Assaf Vardi
The ecological and evolutionary role of programmed cell death in single-celled marine photosynthetic microorganismsThe role of infochemicals and their regulation of cell fate and cell-cell interactions in marine photosynthetic microorganismsSensing Environmental Stress and Acclimation Strategies in Marine AlgaeCell Signaling Pathways and their role in the Chemical Arms Race during Algal Host-Virus and Predator-Prey interactions
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Prof. Itamar Procaccia
The glass transition and slow relaxation phenomenaCollaboration with: Jacques Zylberg, Yossi CohenMechanical properties of amorphus solids with theory of plasticityCollaboration with: Valery Ilyin, Ratul Dasgupta, Limei Xu, Smarajit KarmakarFailure in Amorphuos Media: fracture, shear bands and necking.Collaboration with: Ratul Dasgupta, Ashvin Joy, Eran BouchbinderFractals and scaling in nonequilibrium physics.Turbulence in classical and in quantum fluidsCollaboration with: Victor L'vov, Anna Pomyalov, Laurent Boue'
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Prof. Amnon Horovitz
Linear free energy relationships (LFER) analysis of allosteric transitions in proteins.Analysis of correlated mutations in proteinsCollaboration with: Ron Unger (Bar Ilan University)Allostery in the structure and function of GroEL and CCT chaperonins.Collaboration with: Keith Willison (Cancer Research Institute, London); Michal Sharon;Chaperonin-mediated protein folding.Collaboration with: Gilad Haran; Maya Schuldiner;
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Prof. Eitan Bibi
Structure/function studies of the <I>E. coli</I> multidrug transporter, MdfA.Collaboration with: N. Fluman and O. TiroshThe multidrug recognition pocket of MdfA (genetic and biochemical studies)3D crystallization of MdfAMechanism of MdfA-mediated multidrug transport (proton/drug antiport)Membrane protein biogenesis in E. coliCollaboration with: E.S. Bochkareva, A. Kinori, D. Ben-Halevy, I. NoachFtsY, the essential prokaryotic SRP-receptor: biogenesis and functionMembrane targeting and association of ribosomes in E. coli.Membrane targeting and association of mRNAs encoding membrane proteins
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