Histone ubiquitylation in regulation of gene expression and in cancer.

Role of p53 in tumor-host interactions.

Gain of function of mutant p53 in cancer.

Regulation of the Mdm2 oncoprotein.

Relationship of p53 to programmed cell death.

Molecular biology of p53.

Regulation of proteins by covalent modifications.

Role of microRNAs in cancer.

Immature dendritic cells: investigating a novel granule mediated killing mechanism and the therapeutic potential for the prevention of Graft versus Host Disease.

Crossing allogeneic and xenogeneic barriers by growing organs in-vivo from embryonic tissues : potential curative approaches for diabetes, hemophilia and lung diseases.

Hematopoietic size control: A novel role for coagulation cascade factors in regulating the interplay between dynamic bone structure and long term survival and mobilization of hematopoietic stem cells.

Developing a protocol for the production of human central memory CD8 T cells, to induce tolerance in allogeneic stem cell transplantation.

Investigating the use of activated CD8 T cells as novel cell therapy for the treatment of autoimmune diseases.

Role and mechanism of tolerance induction by activated CD8 T cells: A novel cell therapy for chimerism induction, stem cell transplant engraftment and enhanced Graft versus Lymphoma / Leukemia effect.

Applications of TCR-seq: Autoimmunity, Neuroimmunology, Vaccination.

Mapping T cell receptor repertoire using high-throughput sequencing (TCR-seq): developing methodologies and bioinformatic tools.

Live cell imaging of T cell activation and differentiation using microfluidics devices.

Studies of intercellular cytokine communication networks in T-cell development and differentiation.

Studies of CD4 T cell differentiation combining experimental single cell approaches and mathematical modeling.

Decisions under uncertainty.

Ordinary differential equations, singular perturbations, averaging, nonautonomous systems.

Control and optimal control, singularly perturbed systems, variational analysis.

Molecular origins of biological lubrication Hydration lubrication: a new paradigm

Surface-forces-measurement techniques at angstrom surface separations; polymers as molecular lubricants

Polymers, Complex Fluids, and Interfaces - Experimental studies of the behavior of confined simple and polymeric fluids.

Transcription regulation of the hepatitis B virus. To understand how overlapping promoters are autonomously functional.

The molecular basis of virus-host cell interaction. How HBV modifies cell behavior.

The activation and the role of c-Abl-p73 signaling axis in response to DNA damage and cancer.

modulation of Hippo signaling by c-Abl; the role of Yap1 and TAZ transcription coactivators in cell proliferation and in apoptosis

proteasomes as a target in cancer therapy

proteasome composition, dynamics, function and regulation and various conditions.

proteasomal degradation of intrinsically disordered proteins (IUP or IDP). the concept of degradation by default

Geometric modeling, geometry processing, shape analysis, computer graphics, Discrete differential geometry

Particle Physics and Quantum Field Theory

Bio molecular and molecular (opto)electronics

Solar Energy: New materials and concepts, and understanding of Photovoltaics

Visual formalisms, software engineering, biological modeling, visualization.