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Prof. Avi Ben-Nun
Neuroimmunology, pathogenic autoimmunity, myelin/neuronal repair, and treatment of autoimmune diseases in central nervous system (CNS):T-cell pathogenesis and regulation in autoimmune diseases of the CNS.Effects of functional epistasis between HLA class-II alleles on genetic predisposition to multiple sclerosis (MS) in humanized HLA-Tg mice and MS patients.Defining major pathogenic MS-related myelin/neuronal epitopes in HLA-transgenic (Tg) mice.Antigen-based immune-specific approaches to therapy (and mechanisms) of MS and other T-cell mediated autoimmune diseases.Myelin/neuronal repair by adult neural stem cells in mice with chronic MS-like disease.
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Dr. Haim Beidenkopf
Topological phases of matter:Collaboration with: Claudia Felser, Max Planck Institute, Dresden, Germany Joseph Checkelsky, MIT, USATopological insulatorsWeak topological insulatorsTopological superconductorsCrystalline topological InsulatorsHelical nanowiresScanning tunneling microscopySemiconducting nanowiresCollaboration with: Hadas Shtrikman, WIStopological superconductivityMajorana modeslow-dimensional systemstopological nanowiresNanowires grown of topological materialsmolecular beam epitaxy (MBE)
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Prof. Ed Bayer
Structural and functional aspects of the multi-enzyme cellulosome complex from cellulose-degrading bacteria.The cohesin-dockerin couple - Protein-protein interactions that mediate recognition and specificity in cellulosome assembly.Cellulose-binding domains as models for protein-sugar interactions.Bioinformatics of cellulases and cellulosome componentsComparative genomics of cellulosome components.Structure determination of cellulosome components.Enzymology of cellulosomes for conversion of biomass to biofuelsDesigner cellulosomes - Selective engineering of chimaeric cellulosome constructs for nanotechnology.Avidin-biotin system - Mutated avidins and streptavidins
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Prof. Ruth Arnon
Pathological mechanism in the CNS of various multiple sclerosis animal models.Neuroprotection, neurogenesis and remyelination consequences of Glatiramer Acetate treatment in EAE.Mechanism of action of Copolymer 1 (Copaxone®), a therapeutic vaccine against multiple sclerosis.Collaboration with: M. Sela
