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Prof. Alex Tsafriri
Molecular regulation of ovulatory changes in mammals.Collaboration with: Helena Ashkenazi, Shmulik Motola, Xiumei Cao, Malka Popliker, Seymour Pomerantz, Marco Conti, StanfordThe roles of gonadotropins and EGF-like factors in triggering ovulation.The resumption of meiosis and its regulation.Ovulation as a tissue remodeling process.The development and demise of ovarian follicles <I>in vivo</I> and <I>in vitro</I>: the role of apoptosis.Collaboration with: Atan Gross, KerenYacobi
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Prof. Yoram Shechter
Mechanism of insulin action: Post-binding events in insulin actionPost-receptor agents mimicking insulin.Effect of vanadium <I>in vivo</I> and <I>in vitro</I>.Role of protein tyrosine kinases and protein phosphotyrosine phosphatases in insulin effects.Inhibitors of tyrosine kinases.Chemical modifications of peptides and protein drugs.Novel technologies to prolong life time of peptide and protein drugs.
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Prof. Jacob Anglister
The structure of the membrane proximal extra-cellular region of HIV-1 gp41 and its role in viral fusionCollaboration with: F. NaiderThe structure of the V3 loop of the HIV-1 envelope protein gp120 and its interactions with chemokines receptorsCollaboration with: F. NaiderNMR structure of alpha Interferon complex with its receptorCollaboration with: J. PiehlerThe interactions of scorpion toxins with sodium channels and the structures of the channels extra-cellular loopsCollaboration with: M. Gurevitz, D. Gordon
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