• Picture of Prof. Yoram Shechter

    Prof. Yoram Shechter

    Share Email
    Mechanism of insulin action: Post-binding events in insulin action
    Post-receptor agents mimicking insulin.
    Effect of vanadium <I>in vivo</I> and <I>in vitro</I>.
    Role of protein tyrosine kinases and protein phosphotyrosine phosphatases in insulin effects.
    Inhibitors of tyrosine kinases.
    Chemical modifications of peptides and protein drugs.
    Novel technologies to prolong life time of peptide and protein drugs.

    Homepage
  • Picture of Prof. Yosef Shaul

    Prof. Yosef Shaul

    Share Email
    Transcription regulation of the hepatitis B virus. To understand how overlapping promoters are autonomously functional.
    The molecular basis of virus-host cell interaction. How HBV modifies cell behavior.
    The activation and the role of c-Abl-p73 signaling axis in response to DNA damage and cancer.
    modulation of Hippo signaling by c-Abl; the role of Yap1 and TAZ transcription coactivators in cell proliferation and in apoptosis
    proteasomes as a target in cancer therapy
    proteasome composition, dynamics, function and regulation and various conditions.
    proteasomal degradation of intrinsically disordered proteins (IUP or IDP). the concept of degradation by default

    Homepage
  • Picture of Prof. Michal Sharon

    Prof. Michal Sharon

    Share Email
    Studying large protein complexes involved in the protein degradation pathway using a novel mass spectrometry approach.
    Developing novel methodological approaches for structural mass spectrometry
    Structure-function relationship of the signalosome complex
    Investigation of the 20S ubiquitin-independent degradation pathway

    Homepage
  • Picture of Prof. Ehud Shapiro

    Prof. Ehud Shapiro

    Share Email
    Laying the Biological, Computational and Architectural Foundations for Human Cell Lineage Discovery
    Collaboration with:  E. Shapiro, V. Adalsteinsson, H. Brodi, M. Minden, R. Halaban, C. Klein, M. Meyerson, C. Wu, T. Zukerman, R. Shalom

    Homepage
  • Picture of Prof. Abraham Shanzer

    Prof. Abraham Shanzer

    Share Email
    Supramolecular chemistry
    Biomimetic ion binders, diagnostic tools in imaging technologies (fluorescent probes) and potential therapeutic agents. Synthesis, using classical and combinatorial chemistry methods and evaluation.
    Synthesis and properties of molecular based devices; molecular sensors, switches and logical gates for application in nanotechnology.
    Surface bound functional assemblies.

    Homepage
  • Picture of Dr. Ohad Shamir

    Dr. Ohad Shamir

    Share Email
    Machine Learning, statistical learning, online learning, learning theory, optimization

    Homepage
  • Picture of Prof. Adi Shamir

    Prof. Adi Shamir

    Share Email
    Cryptography, cryptanalysis, electronic money, smartcard security, internet security, complexity theory, the design and analysis of algorithms.
  • Picture of Prof. Zippora Shakked

    Prof. Zippora Shakked

    Share Email
    Crystal structure and solution studies of DNA oligomers.
    Collaboration with:  Donald Crothers (Yale University)
    DNA regulatory elements
    DNA bending by adenine-thymine tracts
    Structural and biochemical studies of proteins involved in transcriptional regulation.
    The tumor-suppressor protein p53 and its interaction with DNA and the basal transcription machinery
    The leukemia-related RUNX1(AML1) transcription regulator

    Homepage

  • Prof. Guy Shakhar

    Share Email
    Dendritic cell behavior:
    The dynamics of antigen sampling, chemokinesis, lymphatic migration
    Antigen presentation by dendritic cells as revealed by intravital imaging
  • Picture of Prof. Yechiel Shai

    Prof. Yechiel Shai

    Share Email
    Membrane-protein interaction and molecular recognition within the membrane milieu. Implication to the function and structure of membrane proteins.
    Assembly and organization of pore forming toxins and ion channels in membranes: Studies with isolated fragments and intact proteins.
    Molecular mechanism of membrane fusion and its inhibition: Studies with HIV and Sendai Virus.
    Molecular basis for cell selectivity by cytolytic antimicrobial peptides.

    Homepage

Pages