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Prof. Avri Ben-Ze'ev
Epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs) and Wnt target genes in colon cancer metastasisThe interplay between the role of GRbeta-catenin in cell adhesion and signaling during colon cancer development.The molecular basis and signaling roles of nerve cell adhesion receptors in colon cancer metastasisThe role of novel GRbeta-catenin target genes in tumor development and metastasis
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Prof. David Fortus
Enhancing Motivation to Learn SciencePolicy ImplementationSchool Culture & PhilosophyTeaching StyleCurriculumAssessmentParents & Peers InluenceIQWST - Investigating and Questioning our World through Science and TechnologyCollaboration with: J. Krajcik & L. Sutherland - University of Michigan, B. Reiser - Northwestern UniversityCoordinated curriculum materialsScientific PracticesLiteracyProject-Based ScienceLarge-Scale EvaluationProfessional DevelopmentWaldorf-Oriented Science EducationAnthroposophyLearning ReadinessHabits of Mind
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Prof. Israel Rubinstein
Functional NanomaterialsSelf-assembled supramolecular nanostructures on surfaces (with A. Vaskevich, H. Leader)Nanoparticle organization on surfaces using coordination layer-by-layer assembly (with A. Vaskevich, H. Leader)Plasmonic systems based on metal nano-island films prepared by evaporation/annealing (with A. Vaskevich)Application of metal nanoisland films in chemical and biological sensing using localized surface plasmon resonance spectroscopy (with A. Vaskevich)
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Prof. Giora Mikenberg
Trigger and data acquisition for LHC experiments.Collaboration with: E. Duchovni, E. Gross, L. Levinson, D. LellouchSearch for Higgs bosons and SUSY particles at LHC.Collaboration with: E. Duchovni, E. Gross, L. Levinson, D. LellouchSearch for Supersymmetry at LEP.Collaboration with: E. Duchovni, E. Gross, L. Levinson, D. LellouchDetector development and study of physics for LHC.Collaboration with: E. Duchovni, E. Gross, L. Levinson, D. LellouchSearch for the standard-model and SUSY Higgs-bosons at LEP.Collaboration with: E. Duchovni, E. Gross, L. Levinson, D. LellouchReconfigurable computing.Collaboration with: E. Duchovni, E. Gross, L. Levinson, D. Lellouch
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Prof. Moshe Oren
Histone ubiquitylation in regulation of gene expression and in cancer.Collaboration with: Prof. Yossi Shiloh, Tel Aviv University, Prof. Robert Roeder, Rockefeller University; Prof. Steven Johnsen, Goettingen University; Dr. Itay Ben-Porath, HUJIRole of p53 in tumor-host interactions.Collaboration with: Dr. Jair Bar, Sheba Medical CenterGain of function of mutant p53 in cancer.Collaboration with: Prof. Varda Rotter, Weizmann Institute; Prof. Vassilis Gorgoulis, Athens University Medical SchoolRegulation of the Mdm2 oncoprotein.Collaboration with: Prof. Yossi Shilo, Tel Aviv UniversityRelationship of p53 to programmed cell death.Molecular biology of p53.Regulation of proteins by covalent modifications.Role of microRNAs in cancer.
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Prof. Yair Reisner
Immature dendritic cells: investigating a novel granule mediated killing mechanism and the therapeutic potential for the prevention of Graft versus Host Disease.Crossing allogeneic and xenogeneic barriers by growing organs in-vivo from embryonic tissues : potential curative approaches for diabetes, hemophilia and lung diseases.Hematopoietic size control: A novel role for coagulation cascade factors in regulating the interplay between dynamic bone structure and long term survival and mobilization of hematopoietic stem cells.Developing a protocol for the production of human central memory CD8 T cells, to induce tolerance in allogeneic stem cell transplantation.Investigating the use of activated CD8 T cells as novel cell therapy for the treatment of autoimmune diseases.Role and mechanism of tolerance induction by activated CD8 T cells: A novel cell therapy for chimerism induction, stem cell transplant engraftment and enhanced Graft versus Lymphoma / Leukemia effect.
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Prof. Nir Friedman
Applications of TCR-seq: Autoimmunity, Neuroimmunology, Vaccination.Collaboration with: R. Arnon, M. Schwartz, B. Chain - UCLMapping T cell receptor repertoire using high-throughput sequencing (TCR-seq): developing methodologies and bioinformatic tools.Live cell imaging of T cell activation and differentiation using microfluidics devices.Studies of intercellular cytokine communication networks in T-cell development and differentiation.Studies of CD4 T cell differentiation combining experimental single cell approaches and mathematical modeling.
