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Prof. Hadassa Degani
Perfusion and angiogensis in lung cancer: The role of the bronchial and pulmonary vascular network using Fluorescence and magnetic resonance imaging methodsMolecular magnetic resonance imaging of the estrogen receptorCollaboration with: Professors David Milstein and Joel Sussman, Weizmann InstituteSynthesis of new, high affinity ligands of the estrogen receptor as probes for molecular imagingStructuaral studies (x-ray crystalography and NMR) of the estrogen receptor - targeted ligands complexFunctional activities and molecular imaging of the new targeted ligands in estrogen receptor positive huaman breast cancer cellsMechanisms of lymphatic metastasis in breast cancer; In vivo fluorescence and magnetic resonanc imagingAdvanced non invasive MRI methods for breast cancer detection and diagnosis ; clinical investigationsCollaboration with: Dr. Myra Shapiro, Meir medical Center3D Tracking of the mammary tree using diffusion tensor magnetic resonance imagingAdvanced methods for analysis of dynamic contrast enhanced MRI based on a combined model free and model based method.Hyperpolarized magnetic resonance spectroscopy and imaging of cancer metabolism; searching for novel metabolic markers of cancerCollaboration with: Professor Lucio Frydman, Weizmann InstituteRenal function through sodium grandients; Non-invasive, high resolution sodium MRI.Collaboration with: Dr. Edna Haran, Weizmann InstituteEstrogen regulation of angiogenesis and perfusion of breast cancer; from molecular mechanisms to functional MRI of the microvascular physiology
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Prof. Michael Elbaum
Cellular Biophysics and Molecular Transport MachinesSingle-molecule manipulations using optical tweezers.Dynamics of DNA uptake into the cell nucleus.Structure and function of the nuclear pore complex (with Z. Reich): application of atomic force microscopy and advanced optical spectroscopies.Anomalous diffusion in polymer networks and living cells (with R. Granek).Organization of forces driving cell movements (with A. Bershadsky): optical force measurements and particle tracking studies; influence of cell biochemistry on biophysical forces.Novel surface-patterning lithographies.
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Prof. David Wallach
Regulation of cell death and tissue damage:Proteins involved in the signaling for the cell-killing (apoptotic and necrotic), immunoregulatory, and inflammatory functions of cytokines of the tumor necrosis factor (TNF) family, and in the regulation of these functions.In vivo models for the functions of the signaling mechanisms activated by ligands of the TNF family and for their pathological aberrations.Natural antagonists to ligands of the TNF family, for protection against the deleterious effects of these cytokines in autoimmune and infectious diseases.Regulation of the activity of the NF kappa B transcription factors.The caspases, their functions and mechanisms of activation.Molecular mechanisms for chronic inflammatory skin diseases.Contributions of aberrations in the function of signaling proteins activated by ligands of the TNF family to cancercancer-cells' survival factors
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Prof. Ilan Koren
The twilight zone - convective clouds and their interaction with the free atmosphereCollaboration with: NOAA-ESRL Boulder CO.Anthropogenic Effects on Clouds and Precipitation and the Derived Climate ForcingCollaboration with: NASA-GSFC, UMBCCloud microphysics and dynamicsCloud classification and cloud textures and morphology
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Prof. Asaph Aharoni
Genetic Regulation of Metabolic Pathways and its Co-ordination with Developmental and Stress Response Programs in Plant BiologyThe Primary-Secondary Metabolism InterfaceRegulation of Plant Surface FormationRegulation of Secondary Metabolism Associated Metabolic PathwaysPlant and Yeast MetabolomicsRiboswitches in Plants: Post Transcriptional Regulators of Metabolic Pathways
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Prof. Adi Kimchi
Programmed Cell Death: from single genes and molecular pathways towards systems level studiesDeciphering the roles of the DAP genes in programmed cell deathSystems biology analysis of the programmed cell death networkFunctional annotations of a family of death-associated kinases: DAPk, DRP-1 and ZIPkProtein translation control during cell death: structure/function analysis of the DAP5 gene
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Prof. Nir Gov
Research of collective quantum effects in Super-fluid, solid and super-solid Helium. Including magnetic phase transitions in solid and liquid helium.The physics of large scale pattern formation of cells in cellular cultures, in morphogenesis and wound-healing.Theoretical problems in biological physics; active processes in cells involving molecular motors.Theoretical studies and modelling of the physics that determines the shapes and dynamics of cells.
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Dr. Michal Armoni
Teaching the foundations of computer science to young studentsTheoretical foundations of computer scienceBasic concepts in algorithm and program designFundamental ideas in computer science: Identifying the core ideas of the discipline, examining their teaching and learning processesReductive thinking: Reduction as a tool for problem solvingNondeterminism: a tool for abstractionReversingAbstraction
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