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Prof. Edit Yerushalmi
Development implementation and evaluation of a 2-year interdisciplinary program for high school chemistry and physics students onCollaboration with: A. Hofstein, S. Livne, Y. Roth, R. Blonder, A. Yarden, S. Safran, B. Eylon, B. GeigerInstructional strategies intended to develop reflective problem solving skills in high school physics studentsCollaboration with: C. Singh, E. Cohen, E. Bagno, B. EylonStudy of the effects of self-diagnosis tasks on learning from physics problem solving.Development, implementation and evaluation of web-based test preparation modules aimed at organizing students knowledge and developing awareness of common misconceptions (Mechanics, Electricity and Magnetism).Development, implementation and research of long-term professional development frameworks for physics high school teachersCollaboration with: R. Safadi, E. Bagno, A. RozenWorkshops for Arab high school physics teachers intended to develop reflective problem solving skills in their students through alternative assessment activities. Workshop approach: Collaborative inquiry into students' self diagnostic activities.Models for collaborative action research workshops for high school physics teachers.Long-term didactical courses introducing pre-service teachers to current research in physics education and its implications to the learning/teaching process.University physics faculty perceptions of learning and teaching problem solving.Collaboration with: C. Henderson, K. Heller, P. Heller, V. Quo, E. Cohen
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Prof. Alex Tsafriri
Molecular regulation of ovulatory changes in mammals.Collaboration with: Helena Ashkenazi, Shmulik Motola, Xiumei Cao, Malka Popliker, Seymour Pomerantz, Marco Conti, StanfordThe roles of gonadotropins and EGF-like factors in triggering ovulation.The resumption of meiosis and its regulation.Ovulation as a tissue remodeling process.The development and demise of ovarian follicles <I>in vivo</I> and <I>in vitro</I>: the role of apoptosis.Collaboration with: Atan Gross, KerenYacobi
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Prof. Yoram Shechter
Mechanism of insulin action: Post-binding events in insulin actionPost-receptor agents mimicking insulin.Effect of vanadium <I>in vivo</I> and <I>in vitro</I>.Role of protein tyrosine kinases and protein phosphotyrosine phosphatases in insulin effects.Inhibitors of tyrosine kinases.Chemical modifications of peptides and protein drugs.Novel technologies to prolong life time of peptide and protein drugs.
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Prof. Matityahu Fridkin
Chemical-Biological and Clinical studies on novel drugs, primarily of peptidic nature,related to therapy of infectious ,inflamatory and neoplastic diseases.Collaboration with: Y. Koch I. Gozes (TAU ) I. Offek (TAU ) R. Catane (TEL-HASHOMER )Anticancer, Antibacterial AntiinflammatoryNovel synthetic and analytical methdologies are being developed.Solid-phase synthesisClassical solution chemistryCombinatorial technologiesStudies include: drug design, pro-drugs, long-acting drugs and drug delivery.Collaboration with: Y. ShechterNovel iron chelatores as potential drugs for neurodegenarative diseasesCollaboration with: M. Youdim ( Technio9n )small-moleculesamino acids and peptides
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Prof. Eytan Domany
Computational Physics: equilibrium and non-equilibrium statistical mechanics of spin glassesCollaboration with: A. P. Young (UCSC)Development of tools and algorithms for large scale data analysis. Bioinformatics.Analysis of high-throughput biological data (in particular, gene expression data)Collaboration with: Several research groups at Weizmann, in the USA and in Europe; see below.Controlled experiments on cell lines and mice (with D. Givol, V. Rotter, Y. Groner, L. Sachs; D. Gazit (Hadassa))Development of antigen chips, applications for autoimmune diseases (with I. Cohen)Studies human cancer samples; leukemia (with E. Canaani; G. Rechavi S. Izraeli (Sheba))Colorectal cancer; (with D. Notterman (UMDNJ), F. Barany (Cornell), P. Paty (MSK), A. Levine (Princeton))Prostate cancer; (with Z. Eshhar, A. Orr (TA Sourasky));Glioblastoma; (with M. Hegi, R. Stupp (CHUV))Breast and cervical cancer (with J-P Thiery, F. Radvanyi, X. Sastre, C. Rosty (Inst Curie))
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