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Prof. Michael Walker
Selective gene expression in pancreatic beta cells:Role of specific transcription factors in expression of the insulin gene in pancreatic beta cells and in control of pancreatic development.Novel beta cell specific genes: isolation, characterization and use as potential tools in diagnosis and therapy of diabetes.
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Prof. Doron Lancet
Genomic and evolutionary analyses of molecular recognition systems.Identification and molecular cloning of members of the olfactory receptor multigene family, including studies of their genome organization, evolution and polymorphisms in humans.Computer analyses of structural models of olfactory receptors and other transmembrane proteins and of receptor affinity distributions.Bioinformatics analysis of long-range DNA sequences and development of whole-genome databases.Computer simulations of selection and evolution in current living organisms and at the origin of life.
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Prof. Yechiel Shai
Membrane-protein interaction and molecular recognition within the membrane milieu. Implication to the function and structure of membrane proteins.Assembly and organization of pore forming toxins and ion channels in membranes: Studies with isolated fragments and intact proteins.Molecular mechanism of membrane fusion and its inhibition: Studies with HIV and Sendai Virus.Molecular basis for cell selectivity by cytolytic antimicrobial peptides.
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Prof. Yoram Salomon
Anti-cancer treatments :Development of novel bacteriochlorophyll-based drugs for photochemotherapy.Boron neutron capture therapy.Reactive oxygen species, their generation by bacteriochlorophyll and light, their role in signal transduction and mechanisms of cell and tumor destruction.Vascular biology and vascular destruction.
