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Prof. Michael Elbaum
Cellular Biophysics and Molecular Transport MachinesSingle-molecule manipulations using optical tweezers.Dynamics of DNA uptake into the cell nucleus.Structure and function of the nuclear pore complex (with Z. Reich): application of atomic force microscopy and advanced optical spectroscopies.Anomalous diffusion in polymer networks and living cells (with R. Granek).Organization of forces driving cell movements (with A. Bershadsky): optical force measurements and particle tracking studies; influence of cell biochemistry on biophysical forces.Novel surface-patterning lithographies.
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Prof. Lea Eisenbach
immunotherapy of cancerCollaboration with: yardena samuels, david bassan, adam solomon, esther tzehovaltumor antigens, engineered lymphocytes, lynch syndrome vaccinesCancer Stem Cells and immunotherapythe role of small interferon induced genes in tumorigenicity and apoptosiscryoimmunotherapytumor escape and toleranceT cell receptor evolution for immunotherapyCollaboration with: David BassanAntigen presentation by engineered MHC moleculesCollaboration with: Dr Gideon Gross
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Prof. Marvin Edelman
Duckweed biotechnologyCollaboration with: Barak Cohen, Ron VunshVolumetric growth of WolffiaPolyploidization of duckweeds for biomass increase and metabolic vigorMutagenesis from photoautotrpphy to photoheterotrophyTransgenic duckweed for veterinary productsGenomic analysis of calcium dependent protein kinases in duckweeds
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Prof. Eytan Domany
Computational Physics: equilibrium and non-equilibrium statistical mechanics of spin glassesCollaboration with: A. P. Young (UCSC)Development of tools and algorithms for large scale data analysis. Bioinformatics.Analysis of high-throughput biological data (in particular, gene expression data)Collaboration with: Several research groups at Weizmann, in the USA and in Europe; see below.Controlled experiments on cell lines and mice (with D. Givol, V. Rotter, Y. Groner, L. Sachs; D. Gazit (Hadassa))Development of antigen chips, applications for autoimmune diseases (with I. Cohen)Studies human cancer samples; leukemia (with E. Canaani; G. Rechavi S. Izraeli (Sheba))Colorectal cancer; (with D. Notterman (UMDNJ), F. Barany (Cornell), P. Paty (MSK), A. Levine (Princeton))Prostate cancer; (with Z. Eshhar, A. Orr (TA Sourasky));Glioblastoma; (with M. Hegi, R. Stupp (CHUV))Breast and cervical cancer (with J-P Thiery, F. Radvanyi, X. Sastre, C. Rosty (Inst Curie))
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