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Prof. Dan Yakir
Developing the use of stable isotopes (in particular, 13C, 18O, 15N, 2H) as tracers of biogeochemical cycles on land.Environmental and climatic influence on the exchange of trace gases and energy between plants, soil and the atmosphere.Climatic influence on the natural abundance of carbon, oxygen and hydrogen isotopes in CO2, O2, H2O and organic matter.
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Prof. Meir Wilchek
Study and application of molecular biorecognitionCollaboration with: Ed Bayer, Talia MironAvidin-biotin system: Studies of the strong binding using chemical, physical and biological methods; new applications of the system.Affinity chromatography: Studies to improve purification of protein by developing new carriers, new activation methods and new principles.Affinity therapy: Development of methods to couple drugs and toxins to biological carriers, such as antibodies, and their delivery to target cells.Garlic-allicin mechanism or reaction
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Prof. Stephen Weiner
Structure - mechanical function relations in mineralized tissues (bones and teeth) using Optical Metrology.Collaboration with: Ron ShaharArchaeological science: revealing the microscopic archaeological recordCollaboration with: E. Boaretto, I Finkelstein, A. Maier, R. Shahack-GrossBiomineralization: mechanisms of mineral formation and growth in biology.Collaboration with: L. Addadi, Irit Sagi, Leeor Kronick
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Prof. David Wallach
Regulation of cell death and tissue damage:Proteins involved in the signaling for the cell-killing (apoptotic and necrotic), immunoregulatory, and inflammatory functions of cytokines of the tumor necrosis factor (TNF) family, and in the regulation of these functions.In vivo models for the functions of the signaling mechanisms activated by ligands of the TNF family and for their pathological aberrations.Natural antagonists to ligands of the TNF family, for protection against the deleterious effects of these cytokines in autoimmune and infectious diseases.Regulation of the activity of the NF kappa B transcription factors.The caspases, their functions and mechanisms of activation.Molecular mechanisms for chronic inflammatory skin diseases.Contributions of aberrations in the function of signaling proteins activated by ligands of the TNF family to cancercancer-cells' survival factors
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Prof. Michael Walker
Selective gene expression in pancreatic beta cells:Role of specific transcription factors in expression of the insulin gene in pancreatic beta cells and in control of pancreatic development.Novel beta cell specific genes: isolation, characterization and use as potential tools in diagnosis and therapy of diabetes.
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Prof. Zvi Vogel
Regulation of microglial activation by cannabinoids: their effects in neurodegenerative and neuroinflammatory diseasesThe antiinflammatory effects of cannabidiol, nonpsychoactive cannabinoid, in autoimmune neuroinflammationCollaboration with:New cannabinoid ligands and their role in neuroinflammatory diseases
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