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April 01, 2015
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Date:21ThursdayJanuary 2016Lecture
Magnetic Resonance Seminar
More information Time 09:30 - 09:30Title High Sensitivity ESR with High Spatial Resolution: Methodologies and ApplicationsLocation Gerhard M.J. Schmidt Lecture HallLecturer Prof. Aharon Blank
Technion, Faculty of ChemistryOrganizer Department of Chemical and Biological PhysicsContact -
Date:21ThursdayJanuary 2016Lecture
How transcription and chromatin state affect DNA repair: A high-resolution genomic study.
More information Time 11:00 - 12:30Location Camelia Botnar BuildingLecturer Dr. Sheera Adar
Dept. of Biochemistry and Biophysics, The Univ.of North Carolina at Chapel HillOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Abstract Damages in DNA present a barrier to transcription ...» Abstract
Damages in DNA present a barrier to transcription and DNA replication. Nucleotide excision repair is the sole mechanism for removing bulky adducts from the human genome. Such adducts include damages formed by ultraviolet (UV) radiation and the chemotherapeutic drugs cisplatin and oxaliplatin. To understand how excision repair is orchestrated despite the packaging of DNA into chromatin, and how repair is coordinated with active transcription, we developed two novel genomic methods for mapping DNA damages and DNA repair at high resolution. These genome-wide maps reveal preferential repair of actively transcribed and open chromatin regions. This includes not only annotated genes but also regulatory regions in the genome. Conversely, repair at heterochromatic and repressed regions is relatively low and continues even two days following UV irradiation. Comparing repair kinetics with existing somatic mutation data from cancer cells shows late-repaired regions are associated with a higher level of cancer-linked mutations. The new genomic assays we’ve developed will be a powerful tool in identifying key components of genome stability, and understanding the genetic and epigenetic changes resulting from genotoxic stress.
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Date:21ThursdayJanuary 2016Colloquia
TBA
More information Time 11:15 - 12:30Location Edna and K.B. Weissman Building of Physical SciencesLecturer Marc Timme
GoettingenOrganizer Faculty of PhysicsContact Abstract Show full text abstract about TBA ...» TBA -
Date:21ThursdayJanuary 2016Lecture
THYMOSINS; FROM DISCOVERY TO CLINICAL APPLICATION
More information Time 14:00 - 15:00Title Guest SeminarLocation Wolfson Building for Biological ResearchLecturer Allan L. Goldstein
The George Washington University School of MedicineOrganizer Department of Systems ImmunologyContact -
Date:21ThursdayJanuary 2016Cultural Events
Folklore festival
More information Time 19:30 - 22:00Location Michael Sela AuditoriumContact -
Date:23SaturdayJanuary 2016Cultural Events
Hen Mizrahi - Stand Up
More information Time 21:30 - 22:45Location Michael Sela AuditoriumContact -
Date:24SundayJanuary 2016Lecture
Path selection in the growth of rivers
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Yossi Cohen
MITOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about The complex pattern of river networks has inspired decades o...» The complex pattern of river networks has inspired decades of studies. However, the evolution and the dynamics of a growing channel remain elusive. Here we show that the principle of local symmetry, a concept originating in fracture mechanics, explains the path followed by growing streams fed by groundwater. Although path selection does not by itself imply a rate of growth, we additionally show how local symmetry may be used to infer how rates of growth scale with water flux. Our methods are applicable to other problems of unstable pattern formation, such as the growth of hierarchical crack patterns and geologic fault networks, where dynamics is not well understood. -
Date:24SundayJanuary 2016Lecture
Agonizing minds: The Monod-Jacobs explorations of gene regulation
More information Time 13:00 - 13:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Dan Tawfik
Dept. of Biological Chemistry, WISOrganizer Department of Molecular GeneticsContact -
Date:25MondayJanuary 201602TuesdayFebruary 2016Conference
ISOTDAQ 2016
More information Time All dayLocation The David Lopatie Conference CentreChairperson Daniel LellouchHomepage Contact -
Date:25MondayJanuary 2016Lecture
Unbiased Reconstruction of Phenome Connections
More information Time 14:00 - 14:00Title Special Guest SeminarLocation Raoul and Graziella de Picciotto Building for Scientific and Technical SupportLecturer Dr. Irit Gat-Vicks Organizer Department of Immunology and Regenerative BiologyContact -
Date:25MondayJanuary 2016Lecture
Permanence and Time irreversibility for particles in turbulence
More information Time 14:15 - 14:15Location Edna and K.B. Weissman Building of Physical SciencesLecturer Ana Frishman
WISOrganizer Department of Physics of Complex SystemsContact Abstract Show full text abstract about Turbulent flows are ubiquitous in nature, present in the a...»
Turbulent flows are ubiquitous in nature, present in the atmosphere, the oceans, in industrial flows and also in one's own bathtub. From an abstract point of view, turbulence is an elemental problem in out-of-equilibrium statistical mechanics. The flow is driven out of equilibrium by forcing and dissipation acting on disparate scales, forming a chaotic motion that spans many interacting scales. Particles placed in a turbulent flow are therefore driven by an out-of-equilibrium fluctuating medium. I will discuss how the breaking of time reversibility of the flow manifests itself in the dynamics of such particles, focusing on tracers following the turbulent velocity field. I will present exact results for time irreversibility of pair dynamics in incompressible as well as compressible flows. For the latter there is an unexpected jump in the dynamics when time is reversed. For the former, I will describe the existence of an all time statistical conservation law for pair dispersion at small scales. In two dimensional or Hamiltonian flows, this conservation law is extended to an exact relation for the probability distribution function of the finite-time Lyapunov exponent. I will show that it can be interpreted as a fluctuation relation in phase space. Lastly, I will review how time irreversibility can be measured for a single particle and will discuss the application of this idea to a simple model of turbulence flow
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Date:26TuesdayJanuary 2016Lecture
I-core Meeting in Memory of Jacob Bekenstein and Zvi Lipkin
More information Time 10:00 - 17:00Location Edna and K.B. Weissman Building of Physical SciencesLecturer Various Speakers Organizer Faculty of PhysicsHomepage Contact -
Date:26TuesdayJanuary 2016Lecture
Inert Anticancer Ti(IV) Complexes of Chelating Phenolato Ligands
More information Time 11:00 - 12:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Edit Tshuva
Department of Chemistry The Hebrew University of JerusalemOrganizer Department of Molecular Chemistry and Materials ScienceContact -
Date:26TuesdayJanuary 2016Lecture
Quantitative Genetics of Metabolic Traits
More information Time 11:15 - 11:15Location Ullmann Building of Life SciencesLecturer Dr. Yariv Brotman
Life Sciences Dept., Faculty of Natural Sciences, Ben-Gurion University of the NegevOrganizer Department of Plant and Environmental SciencesContact -
Date:26TuesdayJanuary 2016Cultural Events
Afternoon Music :The Israel camerata Jerusalem - Free entrance
More information Time 16:30 - 18:30Location Michael Sela AuditoriumHomepage Contact -
Date:27WednesdayJanuary 2016Lecture
Novel insights into cardiac regeneration
More information Time 10:00 - 10:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Eldad Tzahor
Dept. of Biological Regulation, WISContact -
Date:27WednesdayJanuary 2016Lecture
TBD
More information Time 11:15 - 12:15Location Nella and Leon Benoziyo Physics BuildingLecturer Doron Gazit Organizer Nella and Leon Benoziyo Center for AstrophysicsContact -
Date:27WednesdayJanuary 2016Lecture
Emerging Contaminants - The Hidden Time Bombs of Modern Technology
More information Time 12:00 - 13:00Location Gerhard M.J. Schmidt Lecture HallLecturer Dr. Ishai Dror
Department of Earth and Planetary SciencesOrganizer Department of Life Sciences Core FacilitiesContact Abstract Show full text abstract about Many new technologies are based on new materials or novel co...» Many new technologies are based on new materials or novel combinations of elements. This is true for almost any field from pharmaceuticals and personal care products to nanomaterials, and from rare earth metals used in electronic devices to pesticides. Once these technologies become widespread, the release of these substances to the environment is inevitable. These newly introduced chemicals, termed “Emerging Contaminants”, have the potential to pose environmental or public health hazards. However, adequate data do not exist to determine their risk. During the talk, the vicious cycle of new technology that generates new risks which in turn call for improved technologies and potential ways to break this cycle will be discussed. -
Date:28ThursdayJanuary 2016Lecture
p53 and Li-Fraumeni syndrome: A 25 Year Marriage of Science and Medicine
More information Time All dayTitle Cancer Research ClubLocation Raoul and Graziella de Picciotto Building for Scientific and Technical SupportLecturer David Malkin
Hematology/Oncology Senior Scientist, Genetics & Genome Biology Program, The Hospital for Sick Children, CanadaOrganizer Department of Immunology and Regenerative BiologyContact -
Date:28ThursdayJanuary 2016Lecture
Dissecting striatal circuits in learning and decision making
More information Time 12:30 - 12:30Location Gerhard M.J. Schmidt Lecture HallLecturer Prof. Ilana Witten
Princeton Neuroscience Institute, NJOrganizer Department of Brain SciencesContact Abstract Show full text abstract about I will describe two lines of work in mice aimed at dissectin...» I will describe two lines of work in mice aimed at dissecting the role of neuromodulation in the striatum in regulating reward-related learning and decision making. The first story addresses the question of how dopaminergic neurons that innervate the striatum support both learning and action generation, with results suggesting that distinct subpopulations of dopamine neurons support each function. The second story identifies a role for cholinergic interneurons in the ventral striatum in the formation of reward-context associations, with results pointing to a potent ability of the cholinergic neurons in regulating behaviorally-relevant plasticity.
