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January 01, 2016
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Date:02TuesdayMarch 2021Lecture
Quality Control of Misfolded Membrane Proteins
More information Time 10:00 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Nir Fluman
Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about A quarter of the proteome in every living cell is comprised ...» A quarter of the proteome in every living cell is comprised of helical membrane proteins. Our understanding of how they fold, assemble and undergo quality control remains poor, despite relevance to many diseases. I will describe our quest to illuminate the features of unfolded membrane proteins, and how these attributes drive the mechanisms of membrane protein folding and quality control. -
Date:02TuesdayMarch 2021Lecture
Building synthetic microstructural systems to better understand plant-environment interactions
More information Time 11:30 - 12:30Title Guest Seminar via zoomLocation https://weizmann.zoom.us/j/98991032733?pwd=SlJDTWtjQjRJR2FyZEFidXM1MEsvUT09Password187614Lecturer Dr. Maya Kleiman
Department of Vegetables and Field Crops, Institute of Plant Sciences, Agricultural Research Organization ARO-Volcani CenterOrganizer Department of Plant and Environmental SciencesContact -
Date:02TuesdayMarch 2021Lecture
How People Decide What They Want to Know: Information-Seeking and the Human Brain
More information Time 14:30 - 15:30Lecturer Prof. Tali Sharot
Cognitive Neuroscience, Max Planck UCL Centre for Computational Psychiatry and Ageing Research & Department of Experimental Psychology, University College LondonOrganizer Department of Brain SciencesContact Abstract Show full text abstract about The ability to use information to adaptively guide behavior ...» The ability to use information to adaptively guide behavior is central to intelligence. A vital research challenge is to establish how people decide what they want to know. In this talk I will present our recent research characterizing three key motives of information seeking. We find that participants automatically assess (i) how useful information is in directing action, (ii) how it will make them feel, and (iii) how it will influence their ability to predict and understand the world around them. They then integrate these assessments into a calculation of the value of information that guides information-seeking or its avoidance. These diverse influences are captured by separate brain regions along the dopamine reward pathway and are differentially modulated by pharmacological manipulation of dopamine function. The findings yield predictions about how information-seeking behavior will alter in disorders in which the reward system malfunctions. We test these predictions using a linguistic analysis of participants’ web searches ‘in the wild’ to quantify their motives for seeking information and relate those to reported psychiatric symptoms. Finally, using controlled behavioral experiments we show that the three motives for seeking information follow different developmental trajectories that are consistent with what would be predicted from our neuroimaging data.
Zoom link to join:
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
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Date:02TuesdayMarch 2021Lecture
TBA
More information Time 16:00 - 17:00Lecturer Kevin Uno
Lamont-Doherty Earth Observatory Columbia UniversityOrganizer Department of Earth and Planetary SciencesContact -
Date:03WednesdayMarch 2021Lecture
A quantitative perspective on the geo / bio / socio spheres interface
More information Time 09:00 - 10:00Title MSc Thesis Defense via ZoomLocation https://weizmann.zoom.us/j/94410804953?pwd=M1BmbmJ3Y29haDZ4a2xrSkhhVHE5dz09Password997244Lecturer Lior Greenspoon
Prof. Ron Milo's Lab., Department of Plant and Environmental SciencesOrganizer Department of Plant and Environmental SciencesContact -
Date:04ThursdayMarch 2021Lecture
Inflammation, Metabolism and Immunity in Liver Cancer: From Pathogenesis to Treatment
More information Time 09:00 - 10:00Lecturer Dr. Michael Karin
Departments of Pharmacology and Pathology, University of California San Diego, School of MedicineOrganizer Dwek Institute for Cancer Therapy ResearchContact -
Date:04ThursdayMarch 2021Lecture
Using Ultra-High Field MRI to Study the Human Brain
More information Time 09:00 - 10:00Location ZOOMLecturer Dr. Edna Furman-Haran
MRI UnitOrganizer Department of Life Sciences Core FacilitiesHomepage Contact -
Date:04ThursdayMarch 2021Lecture
“Beyond mapping: perturbation as the key to understanding function”
More information Time 09:30 - 10:30Lecturer Dr. Michal Ramot
Dept Neurobiology, WISOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Zoom link: https://weizmann.zoom.us/j/94322871667?pwd=NXkvO...» Zoom link:
https://weizmann.zoom.us/j/94322871667?pwd=NXkvODRXWVZlbW9hSEtScHN1M0F4dz09
passcode: 870711
Neuroimaging has allowed us to map the correlations between brain activation, and external stimuli or behaviour. Yet these correlations can only hint at the function of the brain regions involved. In order to more casually investigate these relationships between brain and behaviour, we must perturb the brain, and see what changes this brings about in behaviour. I will provide a framework for doing so through covert neurofeedback. This technique allows us to perturb brain networks by reinforcing desired network states directly, through a reward orthogonal to the networks being trained. Yet a prerequisite for such a test of function and causality, is a strong hypothesis regarding the purported link between a specific network and behaviour. We must therefore also develop better behavioural tools, in order to establish such links. -
Date:04ThursdayMarch 2021Lecture
Radiocarbon and geochemical investigation of corals from the northern Indian Ocean
More information Time 11:30 - 11:30Location https://weizmann.zoom.us/j/6168548886 Passcode: 976012Lecturer Dr. Harsh Raj
Geosciences Division, Physical Research Laboratory, Navrangpura, Ahmedabad, IndiaContact -
Date:07SundayMarch 202109TuesdayMarch 2021Conference
Biomolecular Phase Separartion: A Student Organzied Conference
More information Time 08:00 - 08:00Location The David Lopatie Conference CentreChairperson Yair Harel -
Date:07SundayMarch 2021Lecture
Department of Molecular Genetics department seminar
More information Time 13:00 - 13:30Title “Ambiguity resolution in the TGFb/ BMP pathways through combinatorial SMAD complex formation”Location https://weizmann.zoom.us/j/92440011671?pwd=Yk9kQUpqWkJnUmFMRUlnT0NaSlliUT09Lecturer Johannes Auth Organizer Department of Molecular GeneticsContact -
Date:08MondayMarch 2021Colloquia
Proteins mobility, affinity & stability for optimized function
More information Time 11:00 - 12:00Location https://weizmann.zoom.us/j/98063488104?pwd=N3VqTC9sU1A4RHVDZ1dhOGVxbU1iUT09Lecturer Prof. Koby Levy
Department of Structural BiologyOrganizer Faculty of ChemistryContact Abstract Show full text abstract about Proteins, which are at the heart of many biological processe...» Proteins, which are at the heart of many biological processes, are involved in a variety of self-assembly processes that are controlled by various chemical and physical interactions. Quantifying the driving forces that govern these processes and particularly the trade-offs between them is essential to obtaining a more complete understanding of protein dynamics and function. In my lecture, I will discuss the molecular determinants that govern linear diffusion of proteins along DNA or along microtubules. These and other cellular processes, such as protein folding, are subject to conflicting forces some of which are regulated by post-translational modifications. Understanding the trade-offs between the stability, affinity and mobility is not only essential to decipher transport processes in the cell but also for formulating concepts for their engineering. I will discuss the power of computational models in formulating fundamental biomolecular concepts and in predicting novel principles of cellular function or for its optimization. -
Date:08MondayMarch 2021Lecture
Women's Day 2021
More information Time 12:30 - 15:00Title Save the dateContact -
Date:09TuesdayMarch 2021Lecture
To be announced
More information Time 10:00 - 10:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Mattia Morandi
Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact -
Date:09TuesdayMarch 2021Lecture
Diatom modulation of associated bacteria
More information Time 11:30 - 12:30Title Guest Seminar via ZoomLocation https://weizmann.zoom.us/j/91943922657?pwd=QnF1eThwV0lWTk45ZWFBWnlHeGx2Zz09Password620591Lecturer Dr. Ahmed Shibl
Marine Microbial Ecology Lab - New York University Abu DhabiOrganizer Department of Plant and Environmental SciencesContact -
Date:09TuesdayMarch 2021Lecture
Dissecting the Alzheimer’s brain: from disease single cells to cellular communities
More information Time 12:30 - 13:30Lecturer Prof. Naomi Habib
Edmond & Lily Safra Center for Brain Sciences, The Hebrew University of JerusalemOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Alzheimer’s disease (AD) is one of the most pressing globa...»
Alzheimer’s disease (AD) is one of the most pressing global medical issues to date with no effective therapeutic strategies. Despite extensive research much remains unknown regarding the crosstalk between brain cells and the role of non-neuronal cells in the progression of Alzheimer’s disease (AD). We use single nucleus RNA-sequencing and machine learning algorithms to build detailed cellular maps of mice and human brain and to follow molecular changes in each cell type along disease progression. Our maps revealed new disease associated states in glia cells as well as unique multi-cellular communities linked to AD. Specifically, we found a link between populations of disease-associated astrocytes (DAAs), microglia, oligodendrocytes and GABAergic neurons to AD related traits in mouse models and in post-mortem human brains. Expanding the data analysis across multiple cell types, we found co-occurrences of cellular populations across individuals, which we define as multi-cellular communities. Among these communities we discovered a unique cellular community linked to cognitive decline and Alzheimer’s disease pathology. These new insights are shaping our understanding of the unique cellular environment of the Alzheimer’s disease brains.
Zoom link to join:
https://weizmann.zoom.us/j/96608033618?pwd=SEdJUkR2ZzRBZ3laUUdGbWR1VFJTdz09
Meeting ID: 966 0803 3618
Password: 564068
Host: Dr. Rita Schmidt rita.schmidt@weizmann.ac.il tel: 9070
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Date:14SundayMarch 2021Lecture
Nucleation fronts initiate frictional motion
More information Time 11:00 - 12:00Lecturer Prof. Jay Fineberg Organizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about Zoom LInk: https://weizmann.zoom.us/j/97917323609?pwd=OGpCV...» Zoom LInk: https://weizmann.zoom.us/j/97917323609?pwd=OGpCVzNKWGlCSS9lbTIyS0FtN1lHUT09
Recent experiments have demonstrated that rapid rupture fronts, akin to earthquakes, mediate the transition to frictional motion. Moreover, once these dynamic rupture fronts ("laboratory earthquakes" ) are created, their singular form, dynamics and arrest are well-described by fracture mechanics. Ruptures, however, need to be created within initially rough frictional interfaces, before they are able to propagate. This is the reason that ``static friction coefficients” are not well-defined; frictional ruptures can nucleate for a wide range of applied forces. A critical open question is, therefore, how the nucleation of rupture fronts actually takes place. We experimentally demonstrate that rupture front nucleation is prefaced by slow nucleation fronts. These nucleation fronts, which are self-similar, are not described by fracture mechanics. They emerge from initially rough frictional interfaces at a well-defined stress threshold, evolve at characteristic velocity and time scales governed by stress levels, and propagate within a frictional interface to form the initial rupture from which fracture mechanics take over. These results are of fundamental importance to questions ranging from earthquake nucleation and prediction to processes governing material failure. -
Date:14SundayMarch 2021Lecture
Department of Molecular Genetics departmental seminar
More information Time 13:00 - 13:30Title “Quantitative analysis by 3D MAPs reveals new cell morphogenetic behaviors which drive bone growth”Location https://weizmann.zoom.us/j/97246877306?pwd=R1FSemROR3hseTNWRDhQeVNBSExWZz09Lecturer Sarah Rubin Organizer Department of Molecular GeneticsContact -
Date:16TuesdayMarch 2021Lecture
Supported Nanocomposites for Water Decontamination
More information Time 10:00 - 11:00Location https://weizmann.zoom.us/j/7621438333?pwd=c0lpdlQzYSthellXWG9rZnM0ZDRFZz09Lecturer Ines Zucker
Tel Aviv UniversityOrganizer Department of Earth and Planetary SciencesContact Abstract Show full text abstract about Contamination of drinking water sources by a variety of orga...» Contamination of drinking water sources by a variety of organic and inorganic compounds demands more efficacious and reliable treatment technologies. However, conventional water treatment technologies remain chemically demanding, energy intensive, and ineffective in removing key trace contaminants. As such, nanotechnology-based approaches have been increasingly explored to enhance or replace traditional remediation methods because of the high reactivity and tunable-properties of nanomaterials. In her talk, Dr. Zucker will provide an overview on the current status of nano-enabled water decontamination, including promising opportunities and barriers for implementation. Specifically, the application of molybdenum disulfide (MoS2) for heavy metal removal will be extensively discussed as a case study, where material properties, removal mechanisms, and large-scale applications are optimized. -
Date:16TuesdayMarch 2021Lecture
Root plasma membrane aquaporins regulate root hydraulics, shoot gas exchange and plant growth
More information Time 11:30 - 12:30Title Guest Seminar via ZoomLocation https://weizmann.zoom.us/j/92082019125?pwd=eUdmSGZIVEc4d3lMWTNNZU02SUZpdz09 Password 879831Lecturer Dr. Nir Sade
School of Plant Sciences and Food Security, The Institute for Cereal Crops Improvement, Tel-Aviv UniversityOrganizer Department of Plant and Environmental SciencesContact
