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February 21, 2016
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Date:25ThursdayJune 2020Lecture
High-dimensional geometry of visual cortex
More information Time 16:00 - 16:00Lecturer Dr. Carsen Stringer
Janelia Research CampusOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Interpreting high-dimensional datasets requires new computat...» Interpreting high-dimensional datasets requires new computational and analytical methods. We developed such methods to extract and analyze neural activity from 20,000 neurons recorded simultaneously in awake, behaving mice. The neural activity was not low-dimensional as commonly thought, but instead was high-dimensional and obeyed a power-law scaling across its eigenvalues. We developed a theory that proposes that neural responses to external stimuli maximize information capacity while maintaining a smooth neural code. We then observed power-law eigenvalue scaling in many real-world datasets, and therefore developed a nonlinear manifold embedding algorithm called Rastermap that can capture such high-dimensional structure. -
Date:28SundayJune 2020Lecture
Departmental seminar by Miri Shnayder
More information Time 13:00 - 13:45Title “HCMV Latent Infection- Lessons from Single Cell Analyses”Location Zoom: https://weizmann.zoom.us/j/99737816120Organizer Department of Molecular GeneticsContact -
Date:30TuesdayJune 2020Lecture
To be announced
More information Time 09:00 - 10:00Title Stem Cells, Regeneration and Aging Breakfast SeminarLocation Max and Lillian Candiotty BuildingOrganizer Department of Immunology and Regenerative BiologyContact -
Date:30TuesdayJune 2020Lecture
Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry
More information Time 10:30 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Shay Vimer
Members - Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about Ortholog protein complexes are responsible for equivalent fu...» Ortholog protein complexes are responsible for equivalent functions in different organisms. However, during evolution, each organism adapts to meet its physiological needs and the environmental challenges imposed by its niche. This selection pressure leads to structural diversity in protein complexes, which are often difficult to specify. Here, we describe a multilevel experimental approach based on native mass spectrometry (MS) tools for elucidating the structural preservation and variations among highly related protein complexes. The 20S proteasome, an essential protein degradation machinery, served as our model system. We compare between four different eukaryotic 20S proteasomes: yeast (Saccharomyces cerevisiae) and mammals (rat - Rattus norvegicus, rabbit - Oryctolagus cuniculus and human - HEK293 cells). Our study revealed that out of four different orthologs the yeast complex, and not those in mammals, was the largest in size and displayed the greatest degree of kinetic stability. Moreover, we also identified a new proteoform of the PSMA7 subunit that resides within the rat and rabbit complexes, which to our knowledge have not been previously described. Altogether, our strategy enables elucidation of the unique structural properties of protein complexes that are highly similar to one another, a framework that is valid not only to ortholog protein complexes, but also for other highly related protein assemblies. -
Date:02ThursdayJuly 2020Lecture
The power of ONE: Immunology in the age of single cell genomics
More information Time 14:00 - 15:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Ido Amit Organizer Dwek Institute for Cancer Therapy ResearchContact -
Date:05SundayJuly 2020Lecture
Departmental Seminar by Mira Rosenthal & Lia Yerushalmi
More information Time 13:00 - 14:00Location Zoom: https://weizmann.zoom.us/j/98416427113Organizer Department of Molecular GeneticsContact -
Date:06MondayJuly 202008WednesdayJuly 2020Conference
ECRICE 2020
More information Time 08:00 - 08:00Location Michael Sela AuditoriumChairperson Ron BlonderHomepage -
Date:06MondayJuly 2020Colloquia
Chemistry Colloquium
More information Time 11:00 - 12:15Title Hydronephrology: When Kidney Stones Encounter HydrologyLocation https://weizmann.zoom.us/j/92910931481Lecturer Prof. Brian Berkowitz
WIS Earth and Planetary SciencesOrganizer Faculty of ChemistryContact -
Date:09ThursdayJuly 2020Colloquia
Students' Colloquium
More information Time 11:15 - 12:30Location https://weizmann.zoom.us/j/98207059710?pwd=L21ZUndGUjY5ajBzckVOeDlPR0Q4dz09Lecturer Aviram Uri, Nirit Sukenik, Asaf Rozen, Or Katz, WIS Organizer Faculty of PhysicsContact -
Date:13MondayJuly 202016ThursdayJuly 2020Conference
Coherent Network Computing 2020 (CNC2020)
More information Time 08:00 - 08:00Location Michael Sela AuditoriumChairperson Nir DavidsonOrganizer Department of Resource Development , Construction Physical Plant Maintenance Division , Department of Chemical and Structural Biology -
Date:16ThursdayJuly 2020Lecture
ClearSight™: A portable system that uses diffusion NMR to probe the margins of excised tumors
More information Time 09:30 - 10:30Organizer Clore Institute for High-Field Magnetic Resonance Imaging and SpectroscopyContact Abstract Show full text abstract about Zoom link: https://weizmann.zoom.us/j/91154950215?pwd=ZkRsTW...» Zoom link: https://weizmann.zoom.us/j/91154950215?pwd=ZkRsTWJzL1AzMWpNbFVSVUF4d05zQT09
Password: 388848
Diffusion NMR weighted NMR and MRI are very powerful techniques for investigating microscopic details about tissue architecture, either normal or in a diseased state. In addition to its traditional use in diagnosing stroke and ischemic injury in the brain, in recent years DWI has been used to diagnose various kinds of cancer, including breast, prostate and lung cancers.
In this seminar we will present an overview of a novel portable system that uses DWI to check whether the margins of excised breast tumors are tumor-free. This is extremely important both for the patient and the hospital, since it obviates the need to perform additional surgery if the subsequent pathology indicates the presence of tumor on the margin of the excised tissue, something that occurs today in up to 25% of breast-conserving surgeries.
We shall provide an overview of diffusion MRI, the unique challenges of performing MRI in or near the operating theater, the architecture of ClearCut's system, computer simulations of its performance and an overview of the clinical results obtained to date.
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Date:16ThursdayJuly 2020Lecture
TP53 mutations playing Dr. Jekyll and Mr. Hyde in the mouse gut
More information Time 14:00 - 15:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Yinon Ben-Neriah Organizer Dwek Institute for Cancer Therapy ResearchContact -
Date:20MondayJuly 2020Colloquia
Chemistry Colloquium
More information Time 11:00 - 12:15Title Atomic Partial Charges in Molecules — Towards A Guide For The PerplexedLocation https://weizmann.zoom.us/j/97794064932?pwd=alJ0VHYxOHRNdlRJS2h1QUVwTjBiUT09Lecturer Prof. Prof. Gershom (Jan M.L.) Martin
Weizmann Institute of Science Department of Organic ChemistryOrganizer Faculty of ChemistryHomepage Contact -
Date:21TuesdayJuly 2020Academic Events
Scientific Council meeting
More information Time 14:00 - 16:00Contact -
Date:29WednesdayJuly 2020Lecture
Deciphering the immunogenomic landscape in melanoma
More information Time 14:00 - 15:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Yardena Samuels Organizer Dwek Institute for Cancer Therapy ResearchContact -
Date:30ThursdayJuly 2020Lecture
Establishing the first tree ring chronology of Amburana cearensis in Brazil and looking beyond population signals
More information Time 11:30 - 12:30Location via ZoomLecturer Milena de Godoy Veiga, Dr. Lior Regev
Group of Ecological Anatomy of Wood and Biology of Parasitic Plants, University of São Paulo, BrazilHomepage Contact -
Date:03MondayAugust 2020Colloquia
Virtual Chemistry Colloquium
More information Time 11:00 - 12:15Title Atmospheric CO2 Triggers Electro-freezing of Super Cooled Water on Pyro-electric SurfacesLocation https://weizmann.zoom.us/j/95804327558?pwd=SkdaWFp6VktRcFptRURLKzBqN093dz09Lecturer Prof. Meir Lahav
Weizmann Institute of Science, Department of Materials and InterfacesOrganizer Faculty of ChemistryHomepage Contact -
Date:10MondayAugust 2020Lecture
Protein Condensation as Cell Survival Strategy in Plant Immunity
More information Time 15:00 - 16:00Title GUEST SEMINAR VIA ZOOMLocation https://weizmann.zoom.us/j/98166822558 - password: 649869Lecturer Dr. Raul Zavaliev, NICOLE FRIESEM
Department of Biology & Howard Hughes Medical Institute, Duke University, USAOrganizer Department of Plant and Environmental SciencesHomepage Contact -
Date:12WednesdayAugust 2020Lecture
Algebraic Geometry and Representation Theory Seminar
More information Time 16:30 - 17:20Title On automorphic descent from GL(7) to G2Organizer Faculty of Mathematics and Computer ScienceContact -
Date:13ThursdayAugust 2020Colloquia
Physical Aspects of Language: Memory, Correlations and Structure in Text and Conversation
More information Time 11:15 - 12:30Location https://weizmann.zoom.us/j/92790893230?pwd=VlRjVzkvaGZ5YWRvcXFGWXVXZ3dXdz09Lecturer Prof. Elisha Moses
WISOrganizer Faculty of PhysicsContact Abstract Show full text abstract about The conversion of ideas and thoughts into a linear train of ...» The conversion of ideas and thoughts into a linear train of words that represents them constitutes a channel of communication that we call language. The capacity for language is a relatively recent evolutionary development in humans, and according to the theory of language established by Chomsky, humans are born with a universal “internal grammar” that enables verbal communication. Although this idea is still controversial, it has support from genetic research: Certain mutations in a gene called FOXP2 significantly impair the ability for grammar. As a natural phenomenon stemming from genes and the brain, language should thus be amenable to the tools of analysis that physics employs with other natural phenomena.
We present three studies on the role of memory and correlations in language. In the first, we investigate the correlation network of words in written texts to identify a hierarchy structures that harnesses memory to bind topics of interest (‘concepts’). In the second study, we see how concepts are established by the existence of loops in a network of words linked by their definitions in a dictionary. Finally, we discuss recent work on how the music, or prosody, adds information to the text. We show that as we convert words into verbal utterances, our short-term memory creates chunks that are then spoken by the vocal chords and muscles. Our approach applies feature-based recognition, which has been extremely successful in image processing, to spoken language. Application to computerized analysis of emphasis in conversation and to the construction of a ‘prosodic dictionary’ will be discussed.
