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February 21, 2016

  • Date:25ThursdayJune 2020

    High-dimensional geometry of visual cortex

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    Time
    16:00 - 16:00
    LecturerDr. Carsen Stringer
    Janelia Research Campus
    Organizer
    Department of Brain Sciences
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    AbstractShow full text abstract about Interpreting high-dimensional datasets requires new computat...»
    Interpreting high-dimensional datasets requires new computational and analytical methods. We developed such methods to extract and analyze neural activity from 20,000 neurons recorded simultaneously in awake, behaving mice. The neural activity was not low-dimensional as commonly thought, but instead was high-dimensional and obeyed a power-law scaling across its eigenvalues. We developed a theory that proposes that neural responses to external stimuli maximize information capacity while maintaining a smooth neural code. We then observed power-law eigenvalue scaling in many real-world datasets, and therefore developed a nonlinear manifold embedding algorithm called Rastermap that can capture such high-dimensional structure.
    Lecture
  • Date:28SundayJune 2020

    Departmental seminar by Miri Shnayder

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    Time
    13:00 - 13:45
    Title
    “HCMV Latent Infection- Lessons from Single Cell Analyses”
    Location
    Zoom: https://weizmann.zoom.us/j/99737816120
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:30TuesdayJune 2020

    To be announced

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    Time
    09:00 - 10:00
    Title
    Stem Cells, Regeneration and Aging Breakfast Seminar
    Location
    Max and Lillian Candiotty Building
    Organizer
    Department of Immunology and Regenerative Biology
    Contact
    Lecture
  • Date:30TuesdayJune 2020

    Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry

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    Time
    10:30 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerShay Vimer
    Members - Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Ortholog protein complexes are responsible for equivalent fu...»
    Ortholog protein complexes are responsible for equivalent functions in different organisms. However, during evolution, each organism adapts to meet its physiological needs and the environmental challenges imposed by its niche. This selection pressure leads to structural diversity in protein complexes, which are often difficult to specify. Here, we describe a multilevel experimental approach based on native mass spectrometry (MS) tools for elucidating the structural preservation and variations among highly related protein complexes. The 20S proteasome, an essential protein degradation machinery, served as our model system. We compare between four different eukaryotic 20S proteasomes: yeast (Saccharomyces cerevisiae) and mammals (rat - Rattus norvegicus, rabbit - Oryctolagus cuniculus and human - HEK293 cells). Our study revealed that out of four different orthologs the yeast complex, and not those in mammals, was the largest in size and displayed the greatest degree of kinetic stability. Moreover, we also identified a new proteoform of the PSMA7 subunit that resides within the rat and rabbit complexes, which to our knowledge have not been previously described. Altogether, our strategy enables elucidation of the unique structural properties of protein complexes that are highly similar to one another, a framework that is valid not only to ortholog protein complexes, but also for other highly related protein assemblies.
    Lecture
  • Date:02ThursdayJuly 2020

    The power of ONE: Immunology in the age of single cell genomics

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    Time
    14:00 - 15:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerProf. Ido Amit
    Organizer
    Dwek Institute for Cancer Therapy Research
    Contact
    Lecture
  • Date:05SundayJuly 2020

    Departmental Seminar by Mira Rosenthal & Lia Yerushalmi

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    Time
    13:00 - 14:00
    Location
    Zoom: https://weizmann.zoom.us/j/98416427113
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:06MondayJuly 202008WednesdayJuly 2020

    ECRICE 2020

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    Time
    08:00 - 08:00
    Location
    Michael Sela Auditorium
    Chairperson
    Ron Blonder
    Homepage
    Conference
  • Date:06MondayJuly 2020

    Chemistry Colloquium

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    Time
    11:00 - 12:15
    Title
    Hydronephrology: When Kidney Stones Encounter Hydrology
    Location
    https://weizmann.zoom.us/j/92910931481
    LecturerProf. Brian Berkowitz
    WIS Earth and Planetary Sciences
    Organizer
    Faculty of Chemistry
    Contact
    Colloquia
  • Date:09ThursdayJuly 2020

    Students' Colloquium

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    Time
    11:15 - 12:30
    Location
    https://weizmann.zoom.us/j/98207059710?pwd=L21ZUndGUjY5ajBzckVOeDlPR0Q4dz09
    LecturerAviram Uri, Nirit Sukenik, Asaf Rozen, Or Katz, WIS
    Organizer
    Faculty of Physics
    Contact
    Colloquia
  • Date:13MondayJuly 202016ThursdayJuly 2020

    Coherent Network Computing 2020 (CNC2020)

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    Time
    08:00 - 08:00
    Location
    Michael Sela Auditorium
    Chairperson
    Nir Davidson
    Organizer
    Department of Resource Development , Construction Physical Plant Maintenance Division , Department of Chemical and Structural Biology
    Conference
  • Date:16ThursdayJuly 2020

    ClearSight™: A portable system that uses diffusion NMR to probe the margins of excised tumors

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    Time
    09:30 - 10:30
    Organizer
    Clore Institute for High-Field Magnetic Resonance Imaging and Spectroscopy
    Contact
    AbstractShow full text abstract about Zoom link: https://weizmann.zoom.us/j/91154950215?pwd=ZkRsTW...»
    Zoom link: https://weizmann.zoom.us/j/91154950215?pwd=ZkRsTWJzL1AzMWpNbFVSVUF4d05zQT09
    Password: 388848


    Diffusion NMR weighted NMR and MRI are very powerful techniques for investigating microscopic details about tissue architecture, either normal or in a diseased state. In addition to its traditional use in diagnosing stroke and ischemic injury in the brain, in recent years DWI has been used to diagnose various kinds of cancer, including breast, prostate and lung cancers.

    In this seminar we will present an overview of a novel portable system that uses DWI to check whether the margins of excised breast tumors are tumor-free. This is extremely important both for the patient and the hospital, since it obviates the need to perform additional surgery if the subsequent pathology indicates the presence of tumor on the margin of the excised tissue, something that occurs today in up to 25% of breast-conserving surgeries.

    We shall provide an overview of diffusion MRI, the unique challenges of performing MRI in or near the operating theater, the architecture of ClearCut's system, computer simulations of its performance and an overview of the clinical results obtained to date.


    Lecture
  • Date:16ThursdayJuly 2020

    TP53 mutations playing Dr. Jekyll and Mr. Hyde in the mouse gut

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    Time
    14:00 - 15:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerProf. Yinon Ben-Neriah
    Organizer
    Dwek Institute for Cancer Therapy Research
    Contact
    Lecture
  • Date:20MondayJuly 2020

    Chemistry Colloquium

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    Time
    11:00 - 12:15
    Title
    Atomic Partial Charges in Molecules — Towards A Guide For The Perplexed
    Location
    https://weizmann.zoom.us/j/97794064932?pwd=alJ0VHYxOHRNdlRJS2h1QUVwTjBiUT09
    LecturerProf. Prof. Gershom (Jan M.L.) Martin
    Weizmann Institute of Science Department of Organic Chemistry
    Organizer
    Faculty of Chemistry
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    Contact
    Colloquia
  • Date:21TuesdayJuly 2020

    Scientific Council meeting

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    Time
    14:00 - 16:00
    Contact
    Academic Events
  • Date:29WednesdayJuly 2020

    Deciphering the immunogenomic landscape in melanoma

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    Time
    14:00 - 15:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    LecturerProf. Yardena Samuels
    Organizer
    Dwek Institute for Cancer Therapy Research
    Contact
    Lecture
  • Date:30ThursdayJuly 2020

    Establishing the first tree ring chronology of Amburana cearensis in Brazil and looking beyond population signals

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    Time
    11:30 - 12:30
    Location
    via Zoom
    LecturerMilena de Godoy Veiga, Dr. Lior Regev
    Group of Ecological Anatomy of Wood and Biology of Parasitic Plants, University of São Paulo, Brazil
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    Lecture
  • Date:03MondayAugust 2020

    Virtual Chemistry Colloquium

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    Time
    11:00 - 12:15
    Title
    Atmospheric CO2 Triggers Electro-freezing of Super Cooled Water on Pyro-electric Surfaces
    Location
    https://weizmann.zoom.us/j/95804327558?pwd=SkdaWFp6VktRcFptRURLKzBqN093dz09
    LecturerProf. Meir Lahav
    Weizmann Institute of Science, Department of Materials and Interfaces
    Organizer
    Faculty of Chemistry
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    Contact
    Colloquia
  • Date:10MondayAugust 2020

    Protein Condensation as Cell Survival Strategy in Plant Immunity

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    Time
    15:00 - 16:00
    Title
    GUEST SEMINAR VIA ZOOM
    Location
    https://weizmann.zoom.us/j/98166822558 - password: 649869
    LecturerDr. Raul Zavaliev, NICOLE FRIESEM
    Department of Biology & Howard Hughes Medical Institute, Duke University, USA
    Organizer
    Department of Plant and Environmental Sciences
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    Contact
    Lecture
  • Date:12WednesdayAugust 2020

    Algebraic Geometry and Representation Theory Seminar

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    Time
    16:30 - 17:20
    Title
    On automorphic descent from GL(7) to G2
    Organizer
    Faculty of Mathematics and Computer Science
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    Lecture
  • Date:13ThursdayAugust 2020

    Physical Aspects of Language: Memory, Correlations and Structure in Text and Conversation

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    Time
    11:15 - 12:30
    Location
    https://weizmann.zoom.us/j/92790893230?pwd=VlRjVzkvaGZ5YWRvcXFGWXVXZ3dXdz09
    LecturerProf. Elisha Moses
    WIS
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about The conversion of ideas and thoughts into a linear train of ...»
    The conversion of ideas and thoughts into a linear train of words that represents them constitutes a channel of communication that we call language. The capacity for language is a relatively recent evolutionary development in humans, and according to the theory of language established by Chomsky, humans are born with a universal “internal grammar” that enables verbal communication. Although this idea is still controversial, it has support from genetic research: Certain mutations in a gene called FOXP2 significantly impair the ability for grammar. As a natural phenomenon stemming from genes and the brain, language should thus be amenable to the tools of analysis that physics employs with other natural phenomena.

    We present three studies on the role of memory and correlations in language. In the first, we investigate the correlation network of words in written texts to identify a hierarchy structures that harnesses memory to bind topics of interest (‘concepts’). In the second study, we see how concepts are established by the existence of loops in a network of words linked by their definitions in a dictionary. Finally, we discuss recent work on how the music, or prosody, adds information to the text. We show that as we convert words into verbal utterances, our short-term memory creates chunks that are then spoken by the vocal chords and muscles. Our approach applies feature-based recognition, which has been extremely successful in image processing, to spoken language. Application to computerized analysis of emphasis in conversation and to the construction of a ‘prosodic dictionary’ will be discussed.
    Colloquia

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