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March 17, 2016

  • Date:06TuesdayDecember 2016

    Subcellular Roles of mTOR in Sciatic Nerve Injury

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    Time
    10:30 - 11:00
    Location
    Wolfson Building for Biological Research
    LecturerDr. Maraco Terenzio
    Members - Dept. of Biomolecular Sciences
    Organizer
    Department of Biomolecular Sciences
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    AbstractShow full text abstract about mTOR is an atypical Ser/Thr kinase that belongs to the PI3K ...»
    mTOR is an atypical Ser/Thr kinase that belongs to the PI3K family and a key sensor of cellular nutritional state, which regulates a vast array of biological processes. Several lines of evidence have highlighted the importance of mTOR signalling in the regeneration of both the central nervous system (CNS) and the peripheral nervous system (PNS). Though localized changes in mTORC1 activity have been documented in axons and linked to synaptic plasticity, it is still unclear whether mTOR peripheral localization and local activation in the sciatic nerve (SN) plays an important role in retrograde survival signalling after injury. Here we show that mTOR mRNA is present in the sciatic nerve and that its protein levels increase after sciatic nerve crush (SNC) at the site of lesion within 3 hr after injury. Mass-spectrometry analyses of SN axoplasm showed that the axonal pool of mTOR is active and responsible for the local activation of two of its downstream kinases, p70S6K and S6, directly at the site of the lesion. Direct monitoring of protein translation revealed that mTOR activation is responsible for most of the early local translational response in the sciatic nerve after injury. Furthermore, local pharmacological inhibition of mTOR at the SNC site by Torin1 impaired the subsequent conditioning lesion response of dorsal root ganglia (DRG) sensory neurons, and caused a reduction of the survival of large proprioceptor DRG neurons after the injury.


    Lecture
  • Date:06TuesdayDecember 2016

    Spectral sum rules for conformal field theories in arbitrary dimensions

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    Time
    10:30 - 10:30
    Location
    Newe Shalom
    LecturerJustin David
    BANGLORE
    Organizer
    Department of Particle Physics and Astrophysics
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    AbstractShow full text abstract about We derive a spectral sum rule in the shear channel for confo...»
    We derive a spectral sum rule in the shear channel for conformal field theories in general d> 2 dimensions held at finite temperature. The sum rule result from the OPE of the stress tensor at high frequency as well as the hydrodynamic behaviour of the theory at low frequencies. The sum rule states that a weighted integral of the spectral density over frequencies is proportional to the energy density of the theory. We show that the proportionality constant can be written in terms the Maldacena-Hofman variables t_2, t_4 which rely on data which determines the three point function of the stress tensor of the CFT. For theories which admit a two derivative gravity dual this proportionality constant is given by d/2(d+1) . We then use causality constraints and obtain bounds on the sum rule which are valid for any conformal field theory. We illustrate the sum rule by applying it to well studied conformal field theories in d=3, 4, 6. dimensions
    Lecture
  • Date:06TuesdayDecember 2016

    “Visualizing nanoscale assembly and fabrication in solution using in situ TEM”

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    Time
    11:00 - 12:15
    Location
    Helen and Milton A. Kimmelman Building
    LecturerProf. Stephen Hashmi
    Department of Biological Sciences & Physics National University of Singapore
    Organizer
    Department of Molecular Chemistry and Materials Science , Department of Molecular Chemistry and Materials Science
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    Lecture
  • Date:06TuesdayDecember 2016

    The eco-hydrology of forest density reduction

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    Time
    11:15 - 11:15
    Location
    Ullmann Building of Life Sciences
    LecturerProf. Naomi (Christina) Tague
    Bren School of Environmental Science and Management University of California, Santa Barbara, USA
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    AbstractShow full text abstract about Ecosystem responses to climatic droughts range from increase...»
    Ecosystem responses to climatic droughts range from increased frequency of stomatal closure and declines in carbon assimilation to plant mortality and increased vulnerability to insects/pathogens and fire. Forest thinning is often posited as a management practice that can reduce mitigate these forest drought responses and may have implications for groundwater recharge and streamflow. There are still relatively few field-based studies of thinning impacts on forest water use. Most of these studies focus only on responses in the first 1-2 years following thinning and show substantial cross-site differences in responses. To extend and better understand field-based findings, we utilize a fully coupled model of ecosystem carbon cycling and hydrology to estimate forest water use, carbon sequestration, regrowth rates and indicators of water stress for different thinning densities. We compare results across climate, topography and soils. For the California Sierra, results emphasize the importance of plant accessible subsurface water storage capacity (PAWSC). We find that a first-order control on system response to thinning is the interactions between PAWSC and climate. We also show that a critical information gap is estimates of the degree to which neighboring trees share water. We conclude by suggesting model applications and new measurements that could be used to help guide decision-making with respect to thinning by accounting for how these multiple controls on thinning ecohydrology interact.
    Lecture
  • Date:06TuesdayDecember 2016

    5D N=1 GAUGE THEORIES VIA 5-BRANE WEB

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    Time
    12:00 - 12:00
    Location
    Newe Shalom
    LecturerFutoshi Yagi
    Technion
    Organizer
    Department of Particle Physics and Astrophysics
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    AbstractShow full text abstract about Due to the recent development of type IIB 5-brane web techni...»
    Due to the recent development of type IIB 5-brane web technique, we are able to study wider class of 5d N=1 gauge theories from the brane constructions. After reviewing this recent development, we focus on a new 5-brane web configuration for 5d N=1 gauge theories with 6d UV fixed points. We observe from brane web that Kaluza-Klein mode of the 6d N=(1,0) SCFT compactified on S^1 is realized as an instanton particle in the corresponding 5d N=1 gauge theory. We also observe that various 5d N=1 gauge theories have identical 6d UV fixed point. We check these observations by computing BPS partition functions for some examples.
    Lecture
  • Date:06TuesdayDecember 2016

    MCB - Students seminar

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    Time
    12:15 - 12:15
    Title
    TBA
    Location
    Wolfson Building for Biological Research
    Organizer
    Department of Molecular Cell Biology
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    Lecture
  • Date:06TuesdayDecember 2016

    Trans-generational epigenetic memory of environmental change in C. elegans

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    Time
    13:00 - 13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerProf. Ben Lehner
    EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation, Barcelona, Spain
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    Lecture
  • Date:06TuesdayDecember 2016

    AMOS journal club

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    Time
    13:15 - 14:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Organizer
    Department of Physics of Complex Systems
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    Lecture
  • Date:06TuesdayDecember 2016

    Sublimation of Love - Russian theater

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    Time
    20:00 - 20:00
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:07WednesdayDecember 2016

    Trust none of what you hear and less of what you see: Living with caspases and dying without them

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    Time
    10:00 - 10:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerProf. Eli Arama
    Dept. of Molecular Genetics, WIS
    Contact
    Lecture
  • Date:07WednesdayDecember 2016

    The airway transcriptome as a biomarker for lung cancer detection and prevention

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    Time
    12:00 - 13:00
    Location
    Camelia Botnar Building
    LecturerProf. Avrum Spira
    Director of the Boston Medical Center Cancer Center at Boston University On
    Contact
    Lecture
  • Date:08ThursdayDecember 2016

    Magnetic Resonance Seminar

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    Time
    09:30 - 09:30
    Title
    Functional Roles of Disordered Proteins:Revisiting the Structure:Function Paradigm
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf. Haribabu Arthanari
    Dept. Biological Chemistry & Molecular Pharmacology (BCMP,Harvard University
    Organizer
    Department of Chemical and Biological Physics
    Contact
    Lecture
  • Date:08ThursdayDecember 2016

    Paul Dirac – the theorists’ theorist

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    LecturerGraham Farmelo
    NA
    Organizer
    Faculty of Physics
    Contact
    AbstractShow full text abstract about Although Paul Dirac was one of the founders of quantum mecha...»
    Although Paul Dirac was one of the founders of quantum mechanics, his peers always perceived him as an outsider, with a unique approach to the subject that was often hard to understand. In this talk, I explain how he came to have such an unusual perspective and why it enabled him to be so productive. In particular, I want to describe the origins of his passion for the idea that mathematical beauty is crucially important to theoreticians who seek the fundamental laws of nature.

    Colloquia
  • Date:08ThursdayDecember 2016

    Spinal cord injuries and brain reorganisation

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    Time
    12:30 - 12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerProf Neeraj Jain
    National Brain Research Centre, Manesar, Haryana, India
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about Adult mammalian brains show remarkable plasticity in respons...»
    Adult mammalian brains show remarkable plasticity in response to deafferentations due to injuries. Lesions of dorsal columns of the spinal cord at cervical levels deafferent sensory inputs from parts of the body below the level of the lesion. Chronic dorsal column injuries in monkeys result in expansion of intact chin inputs into the deafferented hand regions of the primary and secondary somatosensory cortex (area 3 and area S2), ventroposterior lateral nucleus of the thalamus and cuneate nucleus of the brain stem. Our recent evidence suggests that the key plastic change takes place in the brain stem nuclei, perhaps due to axonal growth from the trigeminal nucleus into the cuneate nucleus. This reorganization is then propagated upstream resulting a brain-wide reorganization.

    Lecture
  • Date:08ThursdayDecember 2016

    The Israel Camerata Jerusalem

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    Time
    20:00 - 20:00
    Title
    Sing to the Lord a New Song
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:10SaturdayDecember 2016

    Meni Ozeri - Stand up

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    Time
    21:00 - 21:00
    Location
    Michael Sela Auditorium
    Contact
    Cultural Events
  • Date:11SundayDecember 2016

    A Metabolic Gene Cluster Determines β-Diketone Biosynthesis in Wheat and Barley

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    Time
    10:30 - 10:30
    Location
    Ullmann Building of Life Sciences
    LecturerShelly Hen Avivi
    Prof. Asaph Aharoni's lab., Dept. of Plant & Environmental Sciences
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:11SundayDecember 2016

    Characterization of proteome dynamics in oleate reveals a novel peroxisome targeting receptor

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    Time
    13:00 - 13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    LecturerEden Yifrach
    Maya Schuldiner's group, Dept. of Molecular Genetics,WIS
    Organizer
    Department of Molecular Genetics
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    Lecture
  • Date:12MondayDecember 2016

    Life Science Colloquium

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    Time
    11:00 - 12:00
    Title
    Regulatory T Cells and Control of Inflammation
    Location
    Dolfi and Lola Ebner Auditorium
    LecturerProf. Alexander Rudensky
    Memorial Sloan Kettering Cancer
    Contact
    Colloquia
  • Date:12MondayDecember 2016

    The Role of Philantropy in Science Education

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    Time
    14:30 - 15:45
    Title
    Departmental Seminar- Science Teaching
    Location
    Gerhard M.J. Schmidt Lecture Hall
    LecturerEli Hurvitz
    Organizer
    Department of Science Teaching
    Contact
    Lecture

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