Pages
September 01, 2016
-
Date:25TuesdayJune 2019Lecture
Interactions and function of a protein during its own translation
More information Time 10:00 - 10:15Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Lulu Winer
Members - Dept. of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about The conserved signal recognition particle (SRP) system is es...» The conserved signal recognition particle (SRP) system is essential for the biogenesis of integral membrane proteins (IMPs). The E. coli membrane associated SRP-receptor FtsY is a key player in the SRP system, although very little is known about its targeting and association with the membrane. Previous work done in our lab showed that FtsY targeting to the membrane is of a co-translational nature; during its translation, a specific domain emerges out of the ribosome and serves as the signal for membrane localization. This domain was characterized both functionally and structurally, but the manner by which this entire ribosome-nascent chain complex targets the membrane remains mostly unclear. In order to shed light on this mechanism, we have developed a co-translational and in-vivo site-specific crosslinking system. Using ribosome stalling-sequence and amber suppression, we are trying to identify direct co-translational protein-protein interactions involved in the membrane docking event of FtsY. -
Date:25TuesdayJune 2019Lecture
To be announced
More information Time 10:15 - 10:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Yael Bar-On
Department of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact -
Date:25TuesdayJune 2019Lecture
To be announced
More information Time 10:30 - 11:00Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Anat Bahat
Department of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact -
Date:25TuesdayJune 2019Lecture
Geochemical Dynamics of Atmospheric Oxygen
More information Time 11:00 - 12:00Location Sussman Family Building for Environmental SciencesLecturer Dan Schrag
Harvard UniversityOrganizer Department of Earth and Planetary SciencesContact -
Date:25TuesdayJune 2019Lecture
Suberin - the hidden lipophilic barrier of plants
More information Time 11:30 - 12:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Dr. Hagai Cohen
at Prof. Asaph Aharoni's lab., Dept. of Plant and Environmental SciencesOrganizer Department of Plant and Environmental SciencesContact -
Date:25TuesdayJune 2019Lecture
Development of small-molecule inhibitors targeting bacterial replication and translations
More information Time 14:00 - 15:00Location Helen and Milton A. Kimmelman BuildingLecturer Prof. Barak Akabayov
Ben Gurion UniversityOrganizer Department of Chemical and Structural BiologyContact -
Date:25TuesdayJune 2019Lecture
The Role of DOC2B in Vesicle Fusion and Asynchronous Neurotransmitter Release
More information Time 14:00 - 14:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Uri Ashery
Sagol School of Neuroscience and School of Neurobiology, Biochemistry and Biophysics, Life Sciences Faculty, Tel Aviv UniversityOrganizer Department of Brain SciencesContact Abstract Show full text abstract about DOC2B is a high-affinity Ca2+ sensor, which translocates fro...» DOC2B is a high-affinity Ca2+ sensor, which translocates from the cytosol to the plasma membrane (PM) upon Ca2+ elevation and regulates exocytosis by promoting priming and fusion. Its interaction with the PM depends both on calcium and on its C2 domains binding to phosphoinositides (PI(4,5)P2) at the PM. In the lecture, I will move from the level of protein structure and its targeting to PI(4,5)P2 via its effect on vesicle fusion in chromaffin cells up to its involvement in asynchronous release in neurons and its effects on neuronal network activity. -
Date:26WednesdayJune 2019Lecture
Developmental Club Series 2018-2019
More information Time 10:00 - 10:00Title “Functional characterization and therapeutic targeting of gene regulatory elements”Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Nadav Ahituv Organizer Department of Molecular GeneticsContact -
Date:26WednesdayJune 2019Lecture
Chemical and Biological Physics Dept Seminar
More information Time 13:00 - 13:00Title Theory of Chiral Induced Spin SelectivityLocation Perlman Chemical Sciences BuildingLecturer Prof. Per Hedegaard
Niels Bohr Institute, CopenhagenOrganizer Department of Chemical and Biological PhysicsContact -
Date:27ThursdayJune 2019Lecture
Measuring nanometre distances in biomolecules using EPR Spectroscopy
More information Time 10:00 - 11:00Location Perlman Chemical Sciences BuildingLecturer Dr. Janet Lovett
School of Physics & Astronomy, University of St. AndrewsOrganizer Department of Molecular Chemistry and Materials ScienceContact Abstract Show full text abstract about EPR spectroscopy can be used to measure nanometre-scale dist...» EPR spectroscopy can be used to measure nanometre-scale distances within biomolecules and other soft matter, through determining the dipolar coupling between paramagnetic centres. These can be placed site-specifically within the molecules-of-interest as spin labels. Some experiments that measure the dipolar coupling will be introduced, and results including new spin labels and applications of the methodology will be discussed. -
Date:27ThursdayJune 2019Lecture
PhD Defense Seminar - “The role of neuronal activity and excitability in the coordinated remodeling of the ‘MB circuit’ in Drosophila”
More information Time 11:00 - 11:00Location Raoul and Graziella de Picciotto Building for Scientific and Technical SupportLecturer Oded Mayseless
Prof. Oren Schuldiner's LabOrganizer Department of Molecular Cell BiologyContact -
Date:27ThursdayJune 2019Lecture
special faculty seminar
More information Time 11:15 - 12:30Title “The 2019 redefinition of the SI units and prospects for future optical redefinition of the second”Location Edna and K.B. Weissman Building of Physical SciencesLecturer Prof. Roee Ozeri
WISOrganizer Faculty of PhysicsContact Abstract Show full text abstract about In this seminar I’ll review the rationale behind, and the es...» In this seminar I’ll review the rationale behind, and the essence of, the redefinition of the standard international systems of units that happened on May 20th 2019. I’ll review some of the possible experiments with which standard units can be realized for empirical references. .
-
Date:27ThursdayJune 2019Lecture
Prof. Huib Ovaa DUB-selective reagents
More information Time 14:00 - 15:30Title Dr. Barry Sherman Medical Chemistry and Chemical Biology Seminar SeriesLocation Nella and Leon Benoziyo Building for Biological SciencesLecturer Prof. Huib Ovaa
Leiden University The NetherlandsOrganizer Faculty of BiochemistryContact -
Date:27ThursdayJune 2019Lecture
Cytokines as neuromodulators: How immunity affects brain function
More information Time 14:00 - 14:00Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Prof. Jonathan Kipnis
Center for Brain Immunology and Glia (BIG), Dept of Neuroscience University of Virginia, Charlottesville, VAOrganizer Department of Brain SciencesContact Abstract Show full text abstract about Immune cells and their derived molecules have major impact o...» Immune cells and their derived molecules have major impact on brain function, but despite the robust influence on brain function, peripheral immune cells are not found within the brain parenchyma, a fact that only adds more mystery into these enigmatic interactions between immunity and the brain. Our results suggest that meningeal space, surrounding the brain, is the site where CNS-associated immune activity takes place and through which it impacts brain function. Unique sub-types of immune cells within meningeal spaces are producing certain sets of cytokines that impact specific behaviors. Three main cytokines and their neuromodulatory functions will be discussed in social, learning and risk-taking behaviors. -
Date:27ThursdayJune 2019Lecture
Is chemotherapy obsolete?
More information Time 14:00 - 15:00Location Max and Lillian Candiotty BuildingLecturer Prof. Daniel Hochhauser Organizer Department of Immunology and Regenerative BiologyContact -
Date:27ThursdayJune 2019Lecture
The Palace in Rehovot: Objects in the Weizmann House Tell Their Story
More information Time 19:30 - 21:00Location Weizmann House gardenLecturer The Palace in Rehovot: Objects in the Weizmann House Tell Their Story
Yad Chaim Weizmann cordially invites you to an evening of art and history The Palace in Rehovot: Objects in the Weizmann House Tell Their Story WILL BE GIVEN (IN HEBREW) BY Alec Mishory, historian, curator, art critic and Israeli art researcher Thursday, June 27, 2019 19:30 – Gathering 20:00 – Lecture Weizmann House garden Weizmann Institute of Science, Rehovot * The lecture is open to the public * for information regarding accessibility arrangements and further details: 08-9343230Organizer Yad Chaim WeizmannContact -
Date:30SundayJune 2019Lecture
Influence of terrestrial plants and phytoplankton on photochemical air-pollution
More information Time 11:00 - 11:00Location Sussman Family Building for Environmental SciencesLecturer Eran Tas
Hebrew University of JerusalemOrganizer Department of Earth and Planetary SciencesContact -
Date:30SundayJune 2019Lecture
Departmental Seminar
More information Time 13:00 - 14:00Title “Disease interpretation of non-coding RNA genes”Location Arthur and Rochelle Belfer Building for Biomedical ResearchLecturer Ruth Barshir Organizer Department of Molecular GeneticsContact -
Date:01MondayJuly 2019Academic Events
Scientific Council meeting
More information Time 14:00 - 16:00Location The David Lopatie Conference CentreContact -
Date:02TuesdayJuly 2019Lecture
Probing the conformational behavior of the multidrug transporter MdfA during drug binding and transport.
More information Time 10:00 - 10:30Location Nella and Leon Benoziyo Building for Biological SciencesLecturer Eliane Yardeni
Department of Biomolecular Sciences-WISOrganizer Department of Biomolecular SciencesContact Abstract Show full text abstract about The E. coli secondary multidrug transporter, MdfA from the m...» The E. coli secondary multidrug transporter, MdfA from the major facilitator superfamily (MFS), uses the electrochemical potential to extrude a vast variety of dissimilar drugs from the cytoplasm. It was proposed that MdfA follows the alternating access model, in which its N- and C-terminal domains rock one against the other, exposing the drug binding site either towards the cytoplasm or the periplasm. In our study we aim to analyze the functional states of MdfA to better understand its conformational behavior during drug binding and transport. For this we used double electron-electron resonance and cysteine-cysteine crosslinking to probe intramolecular distances under different conditions, both in detergent micelles and in nanodiscs.