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ינואר 12, 2015

  • Date:27רביעימרץ 2024

    Exploring Inorganic and Organic Biomass for generation of Fuels and Chemical Commodities

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    שעה
    11:00 - 12:00
    מיקום
    בניין פרלמן למדעי הכימיה
    מארגן
    המחלקה לכימיה מולקולרית ולמדע חומרים
    צרו קשר
    תקצירShow full text abstract about Biomass is characterized as "material of biological ori...»
    Biomass is characterized as "material of biological origin, excluding material embedded in
    geological formations or fossilized." It serves as a valuable resource for energy production and as
    a foundational material for the synthesis of various commodity and specialty materials. The
    composition of biomass is notably more diverse and intricate than that of crude oil, resulting in
    significant distinctions between a conventional petroleum refinery and a biomass refinery, often
    referred to as a biorefinery. Unlike crude oil, which is typically abundant in gaseous, liquid, and
    solid hydrocarbons featuring a high carbon-to-oxygen (C/O) ratio, biomass primarily consists of
    complex biomacromolecules with a considerably lower C/O ratio. The conversion of biomass into
    commodity chemicals presents a promising approach to diminish society's reliance on fossil fuel
    resources—the predominant challenge of the 21st century. This challenge necessitates the
    development of tools and technologies to facilitate the transition from a predominantly
    petroleum-based to an alternative bio-based chemical industry. The objective of this seminar is
    to showcase the recent advancements we have made in enhancing bio-based platform
    molecules for the production of commodity or specialty chemicals. We achieve this through the
    utilization of C2 to C6 bio-based platforms, exemplified by polyols (e.g., glycerol), furanoids (e.g.,
    furfural), and carboxylic acids (e.g., levulinic acid).
    הרצאה
  • Date:31ראשוןמרץ 2024

    Large scale circulation adjustments to aerosol-cloud interactions and its radiative effect

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    שעה
    11:00 - 11:00
    מיקום
    בניין משפחת זוסמן
    מרצהGuy Dagan
    Hebrew University of Jerusalem
    מארגן
    המחלקה למדעי כדור הארץ וכוכבי הלכת
    צרו קשר
    תקצירShow full text abstract about The impact of anthropogenic aerosols on clouds is a leading ...»
    The impact of anthropogenic aerosols on clouds is a leading source of uncertainty in estimating the effect of human activity on the climate system. The challenge lies in the scale difference between clouds (~1-10 km) and general circulation and climate (~1000 km). To address this, we utilize three different novel sets of simulations that allow to resolve convection while also including a epresentation of large-scale processes. Our findings demonstrate that aerosol-cloud interaction intensifies tropical overturning circulation. Employing a weak temperature gradient approximation, we attribute variations in circulation to clear-sky humidity changes driven by warm rain suppression by aerosols. In two sets of simulations accounting for sub-tropical-tropical coupling, we show that aerosol-driven sub-tropical rain suppression leads to increased advection of cold and moist air from the sub-tropics to the tropics, thus enhancing tropical cloudiness. The increased tropical cloudiness has a strong cooling effect by reflecting more of the incoming solar radiation. The classical “aerosol-cloud lifetime effect” is shown here to have a strong remote effect (sub-tropical aerosols increase cloudiness in the tropics), thus widening the concept of cloud adjustments to aerosol perturbation with important implications for marine cloud brightening.
    הרצאה
  • Date:31ראשוןמרץ 2024

    Science Literacy for All: Implications for Sustainability Education

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    שעה
    13:00 - 14:00
    כותרת
    IES/SAERI- Sustainability and Energy Research Initiative Seminar Series
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהProf. David Fortus
    Department of Science Teaching -WIS
    מארגן
    ממונה על היוזמה לחקר האנרגיה והקיימות
    צרו קשר
    הרצאה
  • Date:31ראשוןמרץ 2024

    Elucidating sites and mechanisms of GLP-1 action

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    שעה
    15:00 - 16:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהProf. Daniel J Drucker
    Mt. Sinai Hospital, Lunenfeld Tanenbaum Research Institute University of Toronto, Canada.
    צרו קשר
    הרצאה
  • Date:02שלישיאפריל 2024

    iSCAR Seminar

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    שעה
    09:00 - 10:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מארגן
    המחלקה לאימונולוגיה ורגנרציה ביולוגית
    צרו קשר
    הרצאה
  • Date:02שלישיאפריל 2024

    Studying Ageing and Neurodegenerative Brain with Quantitative MRI

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    שעה
    12:30 - 13:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Aviv Mezer
    ELSC for Brain Sciences The Hebrew University of Jerusalem
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    תקצירShow full text abstract about Aging and neurodegeneration are associated with changes in b...»
    Aging and neurodegeneration are associated with changes in brain tissue at the molecular level, affecting its organization, density, and composition. These changes can be detected using quantitative MRI (qMRI), which provides physical measures that are sensitive to structural alterations. However, a major challenge in brain research is to relate physical estimates to their underlying biological sources. In this talk, I will discuss the community's efforts to use qMRI to identify biological processes that underlie changes in brain tissue. Specifically, I will highlight approaches for differentiating between changes in the concentration and composition of myelin and iron during aging. By exploring the molecular landscape of the aging and neurodegenerative brain using qMRI, we aim to gain a better understanding of these processes and potentially provide new metrics for evaluating them.
    הרצאה
  • Date:03רביעיאפריל 2024

    LS Luncheon

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    שעה
    12:00 - 14:00
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהProf. Igor Ulitsky
    צרו קשר
    הרצאה
  • Date:04חמישיאפריל 2024

    A guide towards recombinant protein expression

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    שעה
    09:00 - 10:00
    כותרת
    Fluorescence Labeling of Cancer Cells Using Chemically Modified Bacteria
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    מרצהDr. Tamar Unger
    SPU, LSCF dept & CSB dept
    מארגן
    המחלקה לתשתיות מחקר מדעי החיים
    צרו קשר
    הרצאה
  • Date:04חמישיאפריל 2024

    M.Sc. Thesis Defense Seminar

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    שעה
    11:00 - 12:00
    כותרת
    Characterization of bacterial genomic phenomena using long-read sequencing
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהShai Tamari
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:04חמישיאפריל 2024

    Physics Colloquium

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    שעה
    11:15 - 12:30
    כותרת
    The Rolling Stones, All Down the Line
    מיקום
    בניין הפיזיקה ע"ש עדנה וק.ב. וייסמן
    מרצהProf. Tsvi Tlusti
    UNIST
    מארגן
    המחלקה לפיזיקה של מערכות מורכבות
    צרו קשר
    תקצירShow full text abstract about Draw an arbitrary open curve on the plane and copy it multip...»
    Draw an arbitrary open curve on the plane and copy it multiple times to form a translationally invariant infinite trajectory. Then, incline the plane slightly and ask yourself: can one chisel a stone that will roll exactly down this infinite trajectory?
    We will examine this question in practice and theory. Intriguing links to optics and quantum systems will be discussed. Bringing a tennis ball or a baseball is always recommended.

    Eckmann et al. Tumbling downhill along a given curve. Am Math Soc Notices - in press.
    Sobolev et al. Solid-body trajectoids shaped to roll along desired pathways. Nature 2023.

    סימפוזיונים
  • Date:04חמישיאפריל 2024

    M.Sc. Thesis Defense Seminar

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    שעה
    14:00 - 15:00
    כותרת
    Inference of environmental factors across biomes using community-wide DNA composition
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהTomer Antman
    מארגן
    המחלקה למדעי הצמח והסביבה
    צרו קשר
    הרצאה
  • Date:07ראשוןאפריל 2024

    Benthic side control on the chemical composition of the ocean

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    שעה
    11:00 - 11:00
    מיקום
    בניין משפחת זוסמן
    מרצהZvi Steiner
    GEOMAR Helmholtz Centre
    מארגן
    המחלקה למדעי כדור הארץ וכוכבי הלכת
    צרו קשר
    תקצירShow full text abstract about The sediment – bottom-water interface is suggested as a key ...»
    The sediment – bottom-water interface is suggested as a key control on
    the chemical composition of the ocean by studies of trace elements in the
    ocean water-column, yet data regarding trace element fluxes and
    interactions taking place in the top ten cm of abyssal sediments are
    scarce. To bridge this gap, I analysed the trace and major element
    composition of porewater and sediment of red-clay sediment from the
    abyssal North Pacific, and hydrothermally influenced sediment from the
    Mid-Atlantic Ridge. The top sediment at both study regions is aerobic,
    nevertheless, there is large variability in the porewater concentrations of
    many elements at the top five cm. The North Pacific red-clay sediment is
    a source of cobalt, nickel, copper, arsenic, vanadium and barium to the
    deep-ocean, the magnitude of these fluxes is consistent with fluxes
    calculated based on the water-column distribution of most elements, and
    are equivalent to the global supply of these elements by rivers. The
    hydrothermally influenced sediment is a strong source of copper, zinc
    and cobalt up to three km from the vent due to oxidation of sulfide
    minerals. Close to the vents, the sediment is high in iron oxyhydroxides
    that adsorb the oxyanions vanadate, arsenate and phosphate, acting as
    a sink for these elements. The results of this study highlight the
    importance of red-clay sediment in shaping the chemical composition of
    the ocean, and suggest an important role for hydrothermally influenced
    sediment in modulating the contributions of hydrothermal vents to ocean
    biogeochemistry.
    הרצאה
  • Date:07ראשוןאפריל 2024

    The Clore Center for Biological Physics

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    שעה
    13:15 - 14:30
    כותרת
    Odd Mechanical Screening: From Metamaterial to Continuum Mechanics of Disordered Solids
    מיקום
    המאיץ ע"ש קופלר במרכז קנדה לפיסיקה גרעינית
    מרצהProf. Michael Moshe
    Hebrew University in Jerusalem
    מארגן
    מרכז לפיזיקה ביולוגית עש קלור
    צרו קשר
    תקצירShow full text abstract about Holes in elastic metamaterials, defects in 2D curved crystal...»
    Holes in elastic metamaterials, defects in 2D curved crystals, localized plastic deformations in amorphous solids and T1 transitions in epithelial tissue, are typical realizations of stress-relaxation mechanisms in different solid-like structures, interpreted as mechanical screening.
    In this talk I will present a mechanical screening theory that generalizes classical theories of solids, and introduces new moduli that are missing from the classical theories. Contrary to its electrostatic analog, the screening theory in solids is richer even in the linear case, with multiple screening regimes, predicting qualitatively new mechanical responses.
    The theory is tested in different physical systems, including disordered granular solids that do not have a continuous mechanical description. These materials are shown to violate energy conservation and are best described by Odd-Screening: a screening model that does not derive from an energy function. Experiments reveal a mechanical response that is strictly different from classical solid theory and is completely consistent with our mechanical-screening theory. Finally, I will discuss the relevance of this theory to 3D solids and a new Hexatic-like state in 3D matter.
    הרצאה
  • Date:08שניאפריל 2024

    Midrasha on Groups Seminar

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    שעה
    11:00 - 12:30
    כותרת
    Pushforwards of fractal measures and Diophantine approximation on self-similar sets
    מיקום
    גולדסמית-מתמטיקה
    מרצהBarak Weiss
    TAU
    מארגן
    המחלקה למתמטיקה
    דף בית
    צרו קשר
    תקצירShow full text abstract about Let u be a Bernoulli measure on a fractal in R^d generated ...»
    Let
    u be a Bernoulli measure on a fractal in R^d generated by a finite collection of contracting similarities with no rotations and with rational coefficients
    הרצאה
  • Date:08שניאפריל 2024

    Special Guest Seminar with Dr. Mark Dombrovskiy

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    שעה
    13:30 - 14:30
    כותרת
    Circuit Mechanisms and Molecular Determinants of a Visuomotor Transformation
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהMark Dombrovskiy, Ph.D.
    University of California, Los Angeles; Howard Hughes Medical Institute
    מארגן
    המחלקה לנוירוביולוגיה מולקולרית
    צרו קשר
    הרצאה
  • Date:08שניאפריל 2024

    Midrasha on Groups Seminar

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    שעה
    14:30 - 16:00
    כותרת
    A tale of three problems
    מיקום
    בניין יעקב זיסקינד
    מרצהAlex Lubotzky
    Weizmann
    מארגן
    המחלקה למתמטיקה
    צרו קשר
    תקצירShow full text abstract about In this lecture three fairly elementary problems will be pre...»
    In this lecture three fairly elementary problems will be presented along with their history.

      a. Gromov topological overlapping problem  ( a.k.a. topological expanders).

      b. The existence of good locally testable error-correcting codes.

      c. Are all groups sofic?

    While the three problems appear to be unrelated, the following talks will show that they are! The solutions of the first two will be described and a plan of attack on the third.
    הרצאה
  • Date:09שלישיאפריל 2024

    PhD defense seminar by Yotam Harnik (Prof. Shalev Itzkovitz Lab)

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    שעה
    10:00 - 12:00
    כותרת
    Spatial omics of the murine and human small intestine
    מיקום
    בניין וולפסון למחקר ביולוגי
    מרצהYotam Harnik
    Prof. Shalev Itzkovitz Lab
    מארגן
    המחלקה לביולוגיה מולקולרית של התא
    צרו קשר
    הרצאה
  • Date:09שלישיאפריל 2024

    Inheritance of extrachromosomal DNA in cancer cells

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    שעה
    10:00 - 11:00
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    מרצהInbar Lifshits
    Dept. of Biomolecular Sciences - WIS
    מארגן
    המחלקה למדעים ביומולקולריים
    צרו קשר
    תקצירShow full text abstract about Gene amplification contributing to tumorigenesis and thera...»

    Gene amplification contributing to tumorigenesis and therapy resistance is frequently observed across many cancer types. Amplifications of up to 100’s of oncogene DNA copies can be found within chromosomes in homogenous staining regions (HSRs), or in extrachromosomal DNA (ecDNA) elements (also known as double-minutes or DMs). Amplified genes can be oncogenes such as MYCN but they can also be genes that contribute to therapy resistance. For example, amplification of dihydrofolate reductase (DHFR) can lead to methotrexate (MTX) resistance. DMs are acentric and therefore randomly segregate into daughter cells, thereby driving intra-tumor heterogeneity and increasing gene copy number under selection. Although DMs appear to tether to chromosomes during mitosis, the mechanism underlying their inheritance is not clear. Previous works described tethering based on a few observations and in a very limited manner. This work aimed to extensively examine DM tethering at specific mitosis stages. In addition, the effect of anti-cancer therapies, including DNA damaging agent and microtubule drugs was examined. Elucidating the mechanism of DM tethering could provide insight into the inheritance of other acentric DNA molecules, including DNA from viral sources.
    הרצאה
  • Date:09שלישיאפריל 2024

    Information processing in spiking networks: Converging assemblies

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    שעה
    12:30 - 13:30
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Eran Stark
    Sagol Department of Neurobiology Haifa University
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    תקצירShow full text abstract about How information is processed within the brain is a key quest...»
    How information is processed within the brain is a key question in systems neuroscience. We address the issue in spiking neuronal networks of freely moving mice. I will describe our recent findings and conclusions pertaining to three specific information processing steps: transmission, representation, and storage.
    First, using feedforward optogenetic injection of white noise input to a small group of adjacent neocortical excitatory cells, we find that spike transmission to a postsynaptic cell exhibits error correction, improved precision, and temporal coding. The results are consistent with a nonlinear coincidence detection model in the postsynaptic neuron.
    Second, by triggering input on animal kinematics, we create an artificial place field in an otherwise-silent pyramidal cell. In hippocampal region CA1 but not in the neocortex, artificial fields exhibit synthetic phase precession that persists for a full cycle. The local conversion of an induced rate code into an emerging phase code is compatible with a dual-oscillator interference model.
    Third, by triggering input on spontaneous spiking, we impose self-terminating spike patterns in a group of presynaptic excitatory neurons and a postsynaptic cell. The precise timing of all pre- and postsynaptic spikes has a more substantial impact on long-lasting effective connectivity than that of individual cell pairs, revealing an unexpected plasticity mechanism.
    We conclude that intrinsic properties of single neurons support millisecond-timescale operations, and that cortical networks are organized in functional modules which we refer to as “converging assemblies”.
    הרצאה
  • Date:09שלישיאפריל 2024

    Beyond Touch: Exploring Audible Aspects of Rodent Whisking

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    שעה
    14:00 - 15:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהBen Efron PhD Thesis Defense
    Advisor: Prof. Ilan Lampl
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    תקצירShow full text abstract about Sensory processing is fundamental for animal adaptation and ...»
    Sensory processing is fundamental for animal adaptation and survival, linking them to their environments. Understanding the nervous system's integration of sensory information is crucial for comprehending behavior and cognition. This process involves integrating external cues across modalities, along with internal states, cognitive processes, and motor control, leading to complex behaviors and a nuanced understanding of the world. To facilitate research on these processes, we aimed to identify natural behaviors that produce both auditory and somatosensory stimuli, steering clear of artificial stimulus sources. We discovered that whisking, previously considered a unimodal behavior associated solely with tactile sensations, also produces sounds with distinctive acoustic features within the auditory frequency range of mice. We explored the auditory neuronal representation of sounds generated by whisking and their implications for behavioral performance.  We demonstrate that sounds produced by whisking elicit diverse neuronal responses in the auditory cortex, encoding the object's identity and the mouse's whisking state, even in the absence of tactile sensations. Furthermore, we show that mice are capable of completing behavioral tasks relying solely on auditory cues generated by whisking against objects.
    הרצאה

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