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מרץ 17, 2016
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Date:25רביעימאי 2016הרצאה
TBA
More information שעה 13:30 - 13:30מיקום Technion (Aquarium Room)מרצה Alex Kagan
Cincinnatiמארגן המחלקה לפיזיקה של חלקיקים ואסטרופיזיקהדף בית צרו קשר -
Date:25רביעימאי 2016הרצאה
Sexually dimorphic neuronal connectivity established by sex-specific synapse pruning in C. elegans
More information שעה 14:00 - 15:00מיקום בניין תשתיות ושירותי מחקר על-שם ראול וגרציאלה דה פיצ'וטומרצה Prof. Meital Oren-Suissa
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NYמארגן המחלקה לאימונולוגיה ורגנרציה ביולוגיתצרו קשר -
Date:26חמישימאי 2016הרצאה
Magnetic Resonance Seminar
More information שעה 09:30 - 09:30כותרת Magnetic Molecular Beams - a non-conventional approach for hyper sensitive NMRמיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Gil Alexandrowicz
Schulich Faculty of Chemistry, Technionמארגן המחלקה לפיזיקה כימית וביולוגיתצרו קשר -
Date:26חמישימאי 2016סימפוזיונים
Exploring Flatland
More information שעה 11:15 - 12:30מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Andre Geim
Manchesterמארגן הפקולטה לפיזיקהצרו קשר תקציר Show full text abstract about Following the advent of graphene, many other one-atom or one...» Following the advent of graphene, many other one-atom or one-molecule thick crystals have been isolated and investigated. These two-dimensional crystals have become one of the hottest topics in materials science and condensed matter physics. Furthermore, isolated atomic planes can now be reassembled back into three-dimensional structures and crystals made layer by layer in a designer sequence. I will provide a brief, lowbrow introduction to graphene, trying to explain why this material has attracted so much attention, and then overview our progress in making new assemblies from available atomic planes in order to illustrate how rich in phenomena and application this research field is. -
Date:26חמישימאי 2016הרצאה
Single-molecule views of eukaryotic DNA mismatch repair
More information שעה 14:00 - 14:00מיקום בניין הלן ומילטון קימלמןמרצה Prof. Ilya Finkelstein
Department of Molecular Biosciences & ICMB University of Texas at Austinמארגן המחלקה לביולוגיה מבנית וכימיתצרו קשר -
Date:27שישימאי 2016אירועי תרבות
החברים של נתן - טנגו ארגנטינאי
More information שעה 20:00 - 20:00מיקום אודיטוריום מיכאל סלעצרו קשר -
Date:28שבתמאי 2016אירועי תרבות
סת אל חבייב אמא - מופע עירקי
More information שעה 20:30 - 22:00מיקום אודיטוריום מיכאל סלעצרו קשר -
Date:29ראשוןמאי 201610שישייוני 2016כנסים
Cosmological Probes of Fundamental Physics
More information שעה כל היוםמיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןיושב ראש Kfir Blumצרו קשר -
Date:29ראשוןמאי 2016הרצאה
G-INCPM-Special Seminar - Yael Malkinson Weiss, MD PhD, Executive Director Business Development, Ultragenyx Pharmaceutical, Novato CA - "Developing therapies for rare genetic diseases: weighing traditional versus novel therapeutic modalities"
More information שעה 11:00 - 12:30מיקום המרכז הישראלי הלאומי לרפואה מותאמת אישית על-שם ננסי וסטיבן גרנדמרצה Yael Malkinson Weiss, MD PhD
Executive Director Business Development, Ultragenyx Pharmaceutical, Novato CAמארגן המחלקה למדעים ביומולקולרייםצרו קשר תקציר Show full text abstract about Developing therapies for the treatment of rare genetic disea...» Developing therapies for the treatment of rare genetic disease is frequently perceived to be simpler and with a lower risk than that associated with larger indications. This perception stems from the fact that many of these are monogenic, with predictable genetic effects and clear mechanisms, thus it should be straightforward to replace the defective protein. Since the diseases are usually severe the benefit is large, and in many cases, the rarer the disease, the smaller the clinical trials that are required for registration are.
However, there are over 7,000 genetic diseases with an even larger number of genes affected. The initial approach of protein replacement therapies can be successful but is limited to a relatively small diseases in which the defective proteins are localized in a subset of cellular organelles to which therapeutic proteins will naturally target (lysosome for example). Most of the diseases treatable with traditional protein replacement are becoming very crowded for how small the treatable patient population is. Thus - other solutions need to be considered for the thousands of diseases for which direct proteins replacement is not a viable approach.
Ultragenyx is a biotech company focused on development of therapies for rare genetic diseases. The company’s approach to building its pipeline and deciding how and when to include traditional (protein replacement therapies, small molecules) or new (nucleic acid based therapies) therapeutic modalities will be presented and examples will be discussed.
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Date:29ראשוןמאי 2016הרצאה
The ins and outs of subaerial lithotrophic biofilm in arid and hyper-arid environments
More information שעה 11:00 - 11:00מיקום בניין משפחת זוסמןמרצה Nimrod Wieler
Department of Environmental Hydrology & Microbiology Ben-Gurion University of the Negevמארגן המחלקה למדעי כדור הארץ וכוכבי הלכתצרו קשר תקציר Show full text abstract about Rock surfaces support microbial communities that may be invo...» Rock surfaces support microbial communities that may be involved in weathering processes. In arid and hyper-arid environments microbes dominate rock surfaces and were linked to weathering because the scarcity of water excludes classical mechanisms that erode rocks. We studied subaerial biofilms coating arid rocks, focusing on sedimentary rocks that feature comparable weathering morphologies but different lithologies. We hypothesized that weathering is fashioned by salt erosion and mediated by biofilms that play dual roles: stabilizing the rock surfaces by coating, and enhancing salt crystallization by preventing rapid desiccation (thus mitigating and facilitating erosion processes, respectively). We used a combination of microbial and geological techniques to characterize the rocks morphologies and their subaerial biofilms. Deep sequencing and microscopy analyses suggest that bacterial diversity is low, dominated by Proteobacteria, Cyanobacteria and Actinobacteria. Together these phyla formed laminar biofilms that secrete extracellular polymeric substances to aggregate microfabrics and mitigate desiccation, reducing water loss by over 40%. The biofilm was detected only in rocks exposed to the atmosphere, present distinct architecture and burrowed up to 9 mm beneath the surface, protected by sedimentary deposits. A closer inspection revealed that the composition of the biofilm was tightly linked to dust bacterial communities but distinct from soil communities. Moreover, the biofilm composition changed according to the rock location rather than its’ lithology, suggesting that microclimate (dew, relative humidity and radiation) play an important role in arid weathering. Our results contradict common dogmas that considered biofilms as degrading agents and propose their role as mitigators of geomorphic processes.
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Date:29ראשוןמאי 2016הרצאה
A systematic view on Influenza induced host shut-off
More information שעה 13:00 - 13:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Julie Tai
Noam Stern-Ginossar's group, Dept. of Molecular Genetics, WISמארגן המחלקה לגנטיקה מולקולריתצרו קשר -
Date:29ראשוןמאי 2016הרצאה
The Simple Physics Behind Energy Use
More information שעה 13:00 - 13:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Peter Rez
Department of Physics, Arizona State University, USAמארגן בית הספר למחקר - מכון ויצמן למדעצרו קשר -
Date:29ראשוןמאי 2016הרצאה
Quantitative investigation of birdsong: from learning to performance
More information שעה 13:00 - 13:00מיקום מעבדה על-שם דני נ. היינמןמרצה Prof. Ofer Tchernichovski
Department of Psychology Hunter College, NYCמארגן מרכז לפיזיקה ביולוגית עש קלורצרו קשר תקציר Show full text abstract about • Music maintains a characteristic balance between repetitio...» • Music maintains a characteristic balance between repetition and novelty. I will present evidence for a similar balance in singing performances of free-living Australian pied butcherbirds.
• While acquiring motor skills, such as courtship songs and dances, animals must match their performance to a desired target. However, because both the structure and the temporal position of individual gestures are adjustable, the number of possible motor transformations increases exponentially with sequence length, and searching for the optimal transformation quickly becomes computationally intractable. We show how zebra finches cope with the computational complexity of song learning.
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Date:29ראשוןמאי 2016הרצאה
Antihydrogen - a tool to study matter-antimatter symmetry in the laboratory
More information שעה 14:00 - 14:00מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Eberhard Widmann
President of the Austrian Physical Society Director, Stefan Meyer Institute for Subatomic Physics, Austrian Academy of Sciencesמארגן המחלקה לפיזיקה של חלקיקים ואסטרופיזיקהצרו קשר תקציר Show full text abstract about Antihydrogen, the bound state of an antiproton and a positro...» Antihydrogen, the bound state of an antiproton and a positron, is the simplest atom consisting purely of antimatter. Its matter counterpart, hydrogen, is one of the best studied atomic systems in physics. Thus comparing the spectra of hydrogen and antihydrogen offers some of the most sensitive tests of matter-antimatter symmetry. Furthermore, the availability of neutral antimatter offers for the first time a precise measurement of its gravitational interaction that was so far not possible due to the dominance of the electro-magnetic interaction for charged antiparticles.
The formation and experimental investigation of antihydrogen is the main physics goal of several col-laborations at the Antiproton Decelerator of CERN. The ASACUSA collaboration is pursuing a meas-urement of the ground-state hyperfine structure of antihydrogen in an atomic beam, a quantity which was measured in hydrogen using a maser to a relative precision of 10^{-12}. The AEgIS collaboration aims at using an ultra-cold beam of antihydrogen atoms and a classical moiré deflectometer to determine the gravitational interaction between matter and antimatter in a first step to percent level precision.
After a first production of cold antihydrogen in 2002 and a first trapping in 2010 the experiments are still in the process of optimizing the antihydrogen production from trapped antiprotons and positrons. The status and prospect of these experiments will be reviewed.
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Date:29ראשוןמאי 2016הרצאה
Unraveling unconventional role for astroglial connexins in synaptic strength and memory
More information שעה 15:00 - 15:00מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Nathalie Rouach
CIRB, College de France, Parisמארגן המחלקה למדעי המוחצרו קשר תקציר Show full text abstract about Astrocytes play active roles in brain physiology by dynamic ...» Astrocytes play active roles in brain physiology by dynamic interactions with neurons. Connexin 30, one of the two main astroglial gap-junction subunits, is thought to be involved in behavioral and basic cognitive processes. However, the underlying cellular and molecular mechanisms were unknown. We will show here in mice that connexin 30 controls hippocampal excitatory synaptic transmission through modulation of astroglial glutamate transport, which directly alters synaptic glutamate levels. Unexpectedly, we found that connexin 30 regulated cell adhesion and migration and that connexin 30 modulation of glutamate transport, occurring independently of its channel function, was mediated by morphological changes controlling insertion of astroglial processes into synaptic clefts. By setting excitatory synaptic strength, connexin 30 plays an important role in long-term synaptic plasticity and in hippocampus-based contextual memory. Taken together, these results establish connexin 30 as a critical regulator of synaptic strength by controlling the synaptic location of astroglial processes.
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Date:29ראשוןמאי 2016הרצאה
Braginsky Center for the Interface between the Sciences and the Humanities
More information שעה 15:30 - 15:30כותרת Back to the Future: Recovering “The Age of Wonder”מיקום אולם ע"ש דולפי ולולה אבנרמרצה Prof. David K. Campbell
Boston Universityמארגן המחלקה לפיזיקה כימית וביולוגיתצרו קשר תקציר Show full text abstract about In his remarkable and inspiring book “The Age of Wonder,” Ri...» In his remarkable and inspiring book “The Age of Wonder,” Richard Holmes describes the synergistic links between the sciences and humanities among (in particular) the English intellectuals in the period 1770-1830. “Natural philosophers” like Sir Humphrey Davy had regular interactions with poets like Samuel Taylor Coleridge, and authors like Mary Shelly wrote of dystopias that could result from the misapplication of science and technology. Modern intellectuals, contemplating the current clearly apparent divide between the humanities and the sciences, tend to look at this “age of wonder” through rose-colored glasses and to long for its return. But is this yearning realistic? In our increasingly complex and specialized world, can we truly expect to recover the close bond between these distinct ways of knowing the world? Can we construct an interdisciplinary technological humanism that meaningfully links the sciences and the humanities?
In this talk I attempt to provide limited and subjective answers to these questions and to describe general developments and trends that I believe may give hope that we can indeed recover the “age of wonder.”
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Date:30שנימאי 2016הרצאה
Multi-level scalable proteomic interrogation of intact biological systems
More information שעה 10:00 - 10:00מיקום בניין ארתור ורושל בלפר למחקר ביורפואימרצה Prof. Kwanghun Chung
Department of Chemical Engineering Institute for Medical Engineering and Science (IMES)Picower Institute for Learning and Memory Massachusetts Institute of Technology http://www.chunglab.org/מארגן המחלקה למדעי המוחצרו קשר -
Date:30שנימאי 2016סימפוזיונים
"Chemical Publishing in the 21st Century:Perspectives of a JACS Editor"
More information שעה 11:00 - 12:15מיקום אולם הרצאות ע"ש גרהרד שמידטמרצה Prof. Peter Stang
Department of Chemistry, University of Utahמארגן הפקולטה לכימיהצרו קשר -
Date:30שנימאי 2016הרצאה
The diphoton excess at the LHC
More information שעה 11:00 - 11:00מיקום בניין הפיזיקה ע"ש עדנה וק.ב. וייסמןמרצה Liron Barak
CERNמארגן המחלקה לפיזיקה של חלקיקים ואסטרופיזיקהצרו קשר תקציר Show full text abstract about “Early results from the Run-II of the Large Hadron Collider ...» “Early results from the Run-II of the Large Hadron Collider were recently presented by the ATLAS and CMS experiments. They show hints of an excess in the diphoton mass spectrum near 750 GeV. While these hints might turn out to be statistical fluctuations, they could also be first indications of physics beyond the Standard Model. I will explain in detail the experimental procedures that led to these exciting results. I will further describe the strategy in which we intend to investigate this excess in the near future and either reject or confirm the discovery of new physics.” -
Date:30שנימאי 2016הרצאה
Active DNA Demethylation in Development and Cancer
More information שעה 12:00 - 13:30מיקום בניין קמיליה בוטנארמרצה Prof. Alfonso Bellacosa
Cancer Epigenetics and Cancer Biology Programs, Fox Chase Cancer Center, Philadelphia USAמארגן המחלקה למדעים ביומולקולרייםצרו קשר
